BRPI0917661A2 - produto que contém macitentan, composição farmacêutica que o contém e uso de macitentan - Google Patents

produto que contém macitentan, composição farmacêutica que o contém e uso de macitentan

Info

Publication number: BRPI0917661A2
Authority: BR; Brazil
Prior art keywords: macitentan; pharmaceutical composition; composition containing; product containing; product
Prior art date: 2008-08-13

Application number

BRPI0917661A

Other languages

English (en)

Inventor

Martine Clozel

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-13

Filing date

2009-08-12

Publication date

2015-12-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41346591&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0917661(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2009-08-12 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2015-12-01 Publication of BRPI0917661A2 publication Critical patent/BRPI0917661A2/pt

2019-12-17 Publication of BRPI0917661B1 publication Critical patent/BRPI0917661B1/pt

2021-05-25 Publication of BRPI0917661B8 publication Critical patent/BRPI0917661B8/pt

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4965—Non-condensed pyrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5578—Eicosanoids, e.g. leukotrienes or prostaglandins having a pentalene ring system, e.g. carbacyclin, iloprost
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

BRPI0917661A 2008-08-13 2009-08-12 produto, composição farmacêutica e uso da combinação de macitentan com um composto que é dotado de propriedades agonistas do receptor de prostaciclina BRPI0917661B8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IB2008053252		2008-08-13
PCT/IB2009/053553 WO2010018549A2 (en)	2008-08-13	2009-08-12	Therapeutic compositions containing macitentan

Publications (3)

Publication Number	Publication Date
BRPI0917661A2 true BRPI0917661A2 (pt)	2015-12-01
BRPI0917661B1 BRPI0917661B1 (pt)	2019-12-17
BRPI0917661B8 BRPI0917661B8 (pt)	2021-05-25

Family

ID=41346591

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0917661A BRPI0917661B8 (pt)	2008-08-13	2009-08-12	produto, composição farmacêutica e uso da combinação de macitentan com um composto que é dotado de propriedades agonistas do receptor de prostaciclina

Country Status (29)

Country	Link
US (3)	US8809334B2 (pt)
EP (2)	EP3300729B1 (pt)
JP (3)	JP5764061B2 (pt)
KR (1)	KR101678699B1 (pt)
CN (1)	CN102099026B (pt)
AR (1)	AR073031A1 (pt)
AU (1)	AU2009280843B2 (pt)
BR (1)	BRPI0917661B8 (pt)
CA (1)	CA2731370C (pt)
CY (2)	CY1119826T1 (pt)
DK (2)	DK3300729T3 (pt)
ES (2)	ES2652590T3 (pt)
HK (1)	HK1253355B (pt)
HR (2)	HRP20171917T1 (pt)
HU (2)	HUE047767T2 (pt)
IL (1)	IL211143A0 (pt)
LT (2)	LT3300729T (pt)
MA (1)	MA32614B1 (pt)
MX (1)	MX350011B (pt)
MY (1)	MY178894A (pt)
NO (1)	NO2315587T3 (pt)
NZ (1)	NZ591601A (pt)
PL (2)	PL3300729T3 (pt)
PT (2)	PT3300729T (pt)
RU (1)	RU2519161C2 (pt)
SI (2)	SI2315587T1 (pt)
TW (1)	TWI446911B (pt)
WO (1)	WO2010018549A2 (pt)
ZA (1)	ZA201101900B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY151003A (en)	2005-09-12	2014-03-31	Actelion Pharmaceuticals Ltd	Stable pharmaceutical composition comprising a pyrimidine-sulfamide
MX2010001837A (es)	2007-08-17	2010-03-10	Actelion Pharmaceuticals Ltd	Derivados de 4-pirimidinasulfamida.
CN104761509A (zh) *	2008-02-28	2015-07-08	日本新药株式会社	纤维化抑制剂
NZ591601A (en)	2008-08-13	2012-12-21	Actelion Pharmaceuticals Ltd	Therapeutic compositions containing macitentan and a prostacyclin receptor agonist
EP3712142B1 (en)	2013-01-11	2022-07-06	Corsair Pharma, Inc.	Prodrugs of treprostinil
US9505737B2 (en)	2013-01-11	2016-11-29	Corsair Pharma, Inc.	Treprostinil derivative compounds and methods of using same
US9643911B2 (en)	2015-06-17	2017-05-09	Corsair Pharma, Inc.	Treprostinil derivatives and compositions and uses thereof
US9394227B1 (en)	2015-06-17	2016-07-19	Corsair Pharma, Inc.	Treprostinil derivatives and compositions and uses thereof
US9794795B1 (en)	2016-04-29	2017-10-17	Corning Optical Communications Wireless Ltd	Implementing a live distributed antenna system (DAS) configuration from a virtual DAS design using an original equipment manufacturer (OEM) specific software system in a DAS
MX2019006938A (es)	2016-12-14	2019-09-06	Respira Therapeutics Inc	Metodos y composiciones para trataminto de hipertension pulmonar y otros trastornos del pulmon.
SG11202105098VA (en) *	2018-12-21	2021-06-29	Actelion Pharmaceuticals Ltd	Pharmaceutical composition for the treatment of pulmonary arterial hypertension
TW202042818A (zh)	2019-01-25	2020-12-01	瑞士商艾克泰聯製藥有限公司	用於治療慢性血栓性肺高血壓之醫藥組成物
CA3161960A1 (en)	2019-12-16	2021-06-24	Tenax Therapeutics, Inc.	Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (ph-hfpef)

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4539333A (en)	1976-05-11	1985-09-03	Burroughs Wellcome Co.	Prostacyclin, methods of using and method of making
DE2845770A1 (de)	1978-10-19	1980-04-30	Schering Ag	Neue prostacyclin-derivate und verfahren zu ihrer herstellung
JPS58124778A (ja)	1982-01-20	1983-07-25	Toray Ind Inc	５，６，７−トリノル−４，８−インタ−ｍ−フエニレンＰＧＩ↓２誘導体
US4683330A (en)	1984-03-08	1987-07-28	The Upjohn Company	Interphenylene carbacyclin derivatives
IL155805A0 (en) *	2000-12-18	2003-12-23	Actelion Pharmaceuticals Ltd	Novel sulfamides and their use as endothelin receptor antagonists
JP2004516270A (ja) *	2000-12-19	2004-06-03	メルクパテントゲゼルシャフトミットベシュレンクテルハフトング	ピラゾロ〔４，３−ｄ〕ピリミジンおよび抗血栓剤、カルシウム拮抗剤、プロスタグランジンまたはプロスタグランジン誘導体を含む医薬製剤
DE10100426B4 (de)	2001-01-08	2006-04-06	Steag Hamatech Ag	Verfahren und Vorrichtung zum Zusammenfügen von Substraten
TWI316055B (pt) *	2001-04-26	2009-10-21	Nippon Shinyaku Co Ltd
WO2004017993A1 (en) *	2002-08-12	2004-03-04	Actelion Pharmaceuticals Ltd	Combination of prostacyclin or prostacyclin analogues and endothelin receptor antagonists for the treatment of pulmonary arterial hypertension
ATE423103T1 (de)	2002-12-02	2009-03-15	Actelion Pharmaceuticals Ltd	Pyrimidin-sulfonamide und ihre verwendung als endothelin-rezeptor-antagonisten
US20050101608A1 (en) *	2003-09-24	2005-05-12	Santel Donald J.	Iloprost in combination therapies for the treatment of pulmonary arterial hypertension
TW200628467A (en) *	2004-11-11	2006-08-16	Actelion Pharmaceuticals Ltd	Novel sulfamides
MY151003A (en)	2005-09-12	2014-03-31	Actelion Pharmaceuticals Ltd	Stable pharmaceutical composition comprising a pyrimidine-sulfamide
AR062501A1 (es)	2006-08-29	2008-11-12	Actelion Pharmaceuticals Ltd	Composiciones terapeuticas
RU2494736C2 (ru)	2008-02-20	2013-10-10	Актелион Фармасьютиклз Лтд	Комбинация, включающая паклитаксел, для лечения рака яичников
NZ591601A (en)	2008-08-13	2012-12-21	Actelion Pharmaceuticals Ltd	Therapeutic compositions containing macitentan and a prostacyclin receptor agonist

2009
- 2009-08-12 NZ NZ591601A patent/NZ591601A/xx unknown
- 2009-08-12 EP EP17191033.4A patent/EP3300729B1/en active Active
- 2009-08-12 SI SI200931770T patent/SI2315587T1/en unknown
- 2009-08-12 TW TW098127151A patent/TWI446911B/zh active
- 2009-08-12 RU RU2011109084/15A patent/RU2519161C2/ru active
- 2009-08-12 DK DK17191033.4T patent/DK3300729T3/da active
- 2009-08-12 LT LTEP17191033.4T patent/LT3300729T/lt unknown
- 2009-08-12 DK DK09786912.7T patent/DK2315587T3/en active
- 2009-08-12 BR BRPI0917661A patent/BRPI0917661B8/pt active IP Right Grant
- 2009-08-12 PT PT171910334T patent/PT3300729T/pt unknown
- 2009-08-12 HU HUE17191033A patent/HUE047767T2/hu unknown
- 2009-08-12 CN CN2009801279936A patent/CN102099026B/zh active Active
- 2009-08-12 NO NO09786912A patent/NO2315587T3/no unknown
- 2009-08-12 MX MX2011001625A patent/MX350011B/es active IP Right Grant
- 2009-08-12 PL PL17191033T patent/PL3300729T3/pl unknown
- 2009-08-12 PT PT97869127T patent/PT2315587T/pt unknown
- 2009-08-12 ES ES09786912.7T patent/ES2652590T3/es active Active
- 2009-08-12 HU HUE09786912A patent/HUE036071T2/hu unknown
- 2009-08-12 CA CA2731370A patent/CA2731370C/en active Active
- 2009-08-12 US US13/058,639 patent/US8809334B2/en active Active
- 2009-08-12 PL PL09786912T patent/PL2315587T3/pl unknown
- 2009-08-12 EP EP09786912.7A patent/EP2315587B1/en active Active
- 2009-08-12 MY MYPI2011000637A patent/MY178894A/en unknown
- 2009-08-12 ES ES17191033T patent/ES2763176T3/es active Active
- 2009-08-12 LT LTEP09786912.7T patent/LT2315587T/lt unknown
- 2009-08-12 WO PCT/IB2009/053553 patent/WO2010018549A2/en active Application Filing
- 2009-08-12 SI SI200932016T patent/SI3300729T1/sl unknown
- 2009-08-12 JP JP2011522608A patent/JP5764061B2/ja active Active
- 2009-08-12 AR ARP090103113A patent/AR073031A1/es not_active Application Discontinuation
- 2009-08-12 KR KR1020117003547A patent/KR101678699B1/ko active IP Right Grant
- 2009-08-12 AU AU2009280843A patent/AU2009280843B2/en active Active
2011
- 2011-02-10 IL IL211143A patent/IL211143A0/en active IP Right Grant
- 2011-03-07 MA MA33675A patent/MA32614B1/fr unknown
- 2011-03-11 ZA ZA2011/01900A patent/ZA201101900B/en unknown
2014
- 2014-07-18 US US14/335,657 patent/US9173881B2/en active Active
2015
- 2015-06-12 JP JP2015119021A patent/JP5956026B2/ja active Active
- 2015-06-12 JP JP2015119020A patent/JP5956025B2/ja active Active
- 2015-10-02 US US14/873,787 patent/US9597331B2/en active Active
2017
- 2017-12-11 HR HRP20171917TT patent/HRP20171917T1/hr unknown
2018
- 2018-01-19 CY CY20181100074T patent/CY1119826T1/el unknown
- 2018-10-03 HK HK18112650.6A patent/HK1253355B/zh unknown
2019
- 2019-12-06 HR HRP20192204TT patent/HRP20192204T1/hr unknown
2020
- 2020-01-08 CY CY20201100016T patent/CY1122641T1/el unknown

Also Published As

Publication number	Publication date
KR101678699B1 (ko)	2016-11-23
RU2519161C2 (ru)	2014-06-10
MY178894A (en)	2020-10-21
JP5956025B2 (ja)	2016-07-20
MA32614B1 (fr)	2011-09-01
JP5956026B2 (ja)	2016-07-20
KR20110045006A (ko)	2011-05-03
EP3300729A1 (en)	2018-04-04
DK3300729T3 (da)	2020-01-20
CY1119826T1 (el)	2018-06-27
AU2009280843A1 (en)	2010-02-18
JP2015187148A (ja)	2015-10-29
ZA201101900B (en)	2012-08-29
PT3300729T (pt)	2020-01-20
HRP20192204T1 (hr)	2020-03-06
CA2731370C (en)	2017-03-14
CY1122641T1 (el)	2021-03-12
AU2009280843B2 (en)	2015-03-05
MX350011B (es)	2017-08-22
ES2652590T3 (es)	2018-02-05
EP2315587A2 (en)	2011-05-04
HK1253355A1 (zh)	2019-06-14
HRP20171917T1 (hr)	2018-02-09
DK2315587T3 (en)	2018-01-02
BRPI0917661B1 (pt)	2019-12-17
WO2010018549A2 (en)	2010-02-18
HK1253355B (zh)	2020-06-19
CN102099026A (zh)	2011-06-15
WO2010018549A3 (en)	2010-07-29
PL3300729T3 (pl)	2020-04-30
US9173881B2 (en)	2015-11-03
SI2315587T1 (en)	2018-04-30
TW201010985A (en)	2010-03-16
AR073031A1 (es)	2010-10-06
JP5764061B2 (ja)	2015-08-12
CN102099026B (zh)	2012-08-29
JP2011530581A (ja)	2011-12-22
IL211143A0 (en)	2011-04-28
RU2011109084A (ru)	2012-09-20
US20110136818A1 (en)	2011-06-09
NZ591601A (en)	2012-12-21
SI3300729T1 (sl)	2020-02-28
HUE036071T2 (hu)	2018-06-28
LT3300729T (lt)	2020-01-10
EP3300729B1 (en)	2019-10-09
PT2315587T (pt)	2018-01-31
LT2315587T (lt)	2018-01-10
US8809334B2 (en)	2014-08-19
ES2763176T3 (es)	2020-05-27
CA2731370A1 (en)	2010-02-18
TWI446911B (zh)	2014-08-01
JP2015180683A (ja)	2015-10-15
EP2315587B1 (en)	2017-10-25
US20160022678A1 (en)	2016-01-28
NO2315587T3 (pt)	2018-03-24
BRPI0917661B8 (pt)	2021-05-25
PL2315587T3 (pl)	2018-03-30
US9597331B2 (en)	2017-03-21
MX2011001625A (es)	2011-03-29
US20140329824A1 (en)	2014-11-06
HUE047767T2 (hu)	2020-05-28

Legal Events

Date	Code	Title	Description
2017-10-10	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-04-24	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
2018-08-28	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-02-05	B06A	Patent application procedure suspended [chapter 6.1 patent gazette]
2019-10-15	B09A	Decision: intention to grant [chapter 9.1 patent gazette]
2019-12-17	B16A	Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]	Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/12/2019, OBSERVADAS AS CONDICOES LEGAIS.
2021-05-25	B16C	Correction of notification of the grant [chapter 16.3 patent gazette]	Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 12/08/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

Publication	Publication Date	Title
BRPI0917661A2 (pt)	2015-12-01	produto que contém macitentan, composição farmacêutica que o contém e uso de macitentan
BRPI0809667A2 (pt)	2014-10-07	Composto, medicamento e composição farmacêutica que o contém e uso do composto
BRPI0912717A2 (pt)	2014-12-23	Composição farmacêutica, e, uso de 5-azacitidina
BRPI0921699A2 (pt)	2016-02-16	complexo antioxidante, composicoes cosmeticas e farmaceutica contendo o referido complexo e uso deste complexo
BRPI0917315A2 (pt)	2015-11-17	anticorpo, composicao farmaceutico, e, uso de uma composicao farmaceutica
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BRPI0914343A2 (pt)	2016-07-26	composição, produto, uso da composição e método
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BRPI0908859A2 (pt)	2017-06-06	composição farmacêutica estabilizada de líquído único contedo docetaxel
BRPI0821327A2 (pt)	2015-06-16	Derivado de catecol, composição farmacêutica contendo o mesmo, uso do derivado de catecol, e uso da composição farmacêutica
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