BRPI0915761A2 - composto de heterociclila para tratamento de doença cardiovascular - Google Patents
composto de heterociclila para tratamento de doença cardiovascularInfo
- Publication number
- BRPI0915761A2 BRPI0915761A2 BRPI0915761A BRPI0915761A BRPI0915761A2 BR PI0915761 A2 BRPI0915761 A2 BR PI0915761A2 BR PI0915761 A BRPI0915761 A BR PI0915761A BR PI0915761 A BRPI0915761 A BR PI0915761A BR PI0915761 A2 BRPI0915761 A2 BR PI0915761A2
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- cardiovascular disease
- heterocyclyl compound
- heterocyclyl
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/08—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/36—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08160534 | 2008-07-16 | ||
PCT/EP2009/058467 WO2010006938A1 (en) | 2008-07-16 | 2009-07-06 | Novel heterocyclyl compounds for treatment of cardiovascular disease |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0915761A2 true BRPI0915761A2 (pt) | 2015-11-03 |
Family
ID=41056920
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0915761A BRPI0915761A2 (pt) | 2008-07-16 | 2009-07-06 | composto de heterociclila para tratamento de doença cardiovascular |
Country Status (14)
Country | Link |
---|---|
US (1) | US8071586B2 (pt) |
EP (1) | EP2307387B1 (pt) |
JP (1) | JP5368556B2 (pt) |
KR (1) | KR101268630B1 (pt) |
CN (1) | CN102089289A (pt) |
AR (1) | AR072747A1 (pt) |
AU (1) | AU2009272893A1 (pt) |
BR (1) | BRPI0915761A2 (pt) |
CA (1) | CA2730056A1 (pt) |
ES (1) | ES2439969T3 (pt) |
IL (1) | IL209819A0 (pt) |
MX (1) | MX2011000404A (pt) |
TW (1) | TW201004937A (pt) |
WO (1) | WO2010006938A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012078777A1 (en) | 2010-12-09 | 2012-06-14 | Amgen Inc. | Bicyclic compounds as pim inhibitors |
US9221821B2 (en) * | 2012-06-05 | 2015-12-29 | Forest Laboratories Holdings, Limited | Methods for the synthesis of 1,3-substituted aminouracils and other xanthine-related compounds |
NO2721710T3 (pt) | 2014-08-21 | 2018-03-31 | ||
EP3523280A1 (en) * | 2016-10-06 | 2019-08-14 | Janssen Pharmaceutica NV | Processes and intermediates for preparing a btk inhibitor |
EP3336371B1 (en) | 2016-12-13 | 2019-10-30 | Internordic Bearings AB | Bearing seal |
CN111423454B (zh) * | 2020-04-24 | 2021-06-22 | 苏州大学 | 哌嗪类化合物及其在制备趋化因子受体ccr2拮抗剂中的应用 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003529531A (ja) * | 1998-11-25 | 2003-10-07 | アヴェンティス ファーマシューティカルズ インコーポレイテッド | 置換オキソアザへテロシクリルXa因子阻害剤 |
CZ20024199A3 (cs) * | 2000-05-25 | 2004-01-14 | F. Hoffmann-La Roche Ag | Substituované 1-aminoalkyllaktamy a jejich použití jako antagonisty muskarinového receptoru |
EP1326867A2 (en) * | 2000-10-19 | 2003-07-16 | Pfizer Products Inc. | Bridged piperazine derivatives |
EP1627876A1 (en) | 2004-08-20 | 2006-02-22 | Ferring B.V. | Heterocyclic condensed compounds useful as antidiuretic agents |
EP1831164A1 (en) * | 2004-12-24 | 2007-09-12 | AstraZeneca AB | Heterocyclic compounds as ccr2b antagonists |
BRPI0710512A2 (pt) * | 2006-04-20 | 2012-06-05 | Hoffmann La Roche | moduladores derivados de diazepan de receptores de quimiocinas |
WO2008136754A1 (en) | 2007-05-07 | 2008-11-13 | Astrazeneca Ab | Novel benzyl - 2 -oxo-piperazinyl/ 7-oxo/5-oxa- [1,4] diazepanyl/ 2 -oxo- tetrahydropyrimidinyl derivatives |
AU2008277796A1 (en) | 2007-07-19 | 2009-01-22 | F. Hoffmann-La Roche Ag | Novel heterocyclyl compounds and their use as chemokine antagonists |
-
2009
- 2009-07-06 ES ES09780158.3T patent/ES2439969T3/es active Active
- 2009-07-06 WO PCT/EP2009/058467 patent/WO2010006938A1/en active Application Filing
- 2009-07-06 BR BRPI0915761A patent/BRPI0915761A2/pt not_active IP Right Cessation
- 2009-07-06 KR KR1020117001029A patent/KR101268630B1/ko not_active IP Right Cessation
- 2009-07-06 MX MX2011000404A patent/MX2011000404A/es active IP Right Grant
- 2009-07-06 CN CN2009801273982A patent/CN102089289A/zh active Pending
- 2009-07-06 CA CA2730056A patent/CA2730056A1/en not_active Abandoned
- 2009-07-06 AU AU2009272893A patent/AU2009272893A1/en not_active Abandoned
- 2009-07-06 EP EP09780158.3A patent/EP2307387B1/en not_active Not-in-force
- 2009-07-06 JP JP2011517852A patent/JP5368556B2/ja not_active Expired - Fee Related
- 2009-07-08 US US12/499,120 patent/US8071586B2/en not_active Expired - Fee Related
- 2009-07-13 TW TW098123633A patent/TW201004937A/zh unknown
- 2009-07-15 AR ARP090102672A patent/AR072747A1/es unknown
-
2010
- 2010-12-07 IL IL209819A patent/IL209819A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
KR20110022671A (ko) | 2011-03-07 |
AR072747A1 (es) | 2010-09-15 |
US20100016282A1 (en) | 2010-01-21 |
WO2010006938A1 (en) | 2010-01-21 |
EP2307387B1 (en) | 2013-11-20 |
KR101268630B1 (ko) | 2013-05-29 |
US8071586B2 (en) | 2011-12-06 |
JP5368556B2 (ja) | 2013-12-18 |
TW201004937A (en) | 2010-02-01 |
AU2009272893A1 (en) | 2010-01-21 |
EP2307387A1 (en) | 2011-04-13 |
CN102089289A (zh) | 2011-06-08 |
JP2011528001A (ja) | 2011-11-10 |
ES2439969T3 (es) | 2014-01-27 |
IL209819A0 (en) | 2011-02-28 |
CA2730056A1 (en) | 2010-01-21 |
MX2011000404A (es) | 2011-03-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0910282A2 (pt) | Composto oxadiazo-antraceno para o tratamento de diabetes | |
BRPI0908026A2 (pt) | Métodos para o tratamento de doenças do intestino | |
BRPI0906746A2 (pt) | Aparelho para tratamento de doença de refluxo gastresofágico | |
BRPI1012116A2 (pt) | composição farmacêutica para o tratamento de doenças cardíacas | |
BRPI0917575A2 (pt) | métodos de tratamento de talassemia | |
BRPI0910854A2 (pt) | métodos de tratamento | |
DK2222272T3 (da) | Behandling af luftvejssygdom | |
BRPI0923433A2 (pt) | Síntese de compostos fucosilados | |
BRPI0911923A2 (pt) | dispositivos filamentosos para o tratamento de defeitos vasculares | |
SMT201700090B (it) | Donatori di nitrossile per il trattamento di ipertensione polmonare | |
BRPI0915032A2 (pt) | hidrogenação de alcanos multi-bromados | |
BRPI1007600A2 (pt) | composições e métodos para tratamento de doenças cardiovasculares | |
BRPI1009783A2 (pt) | compostos para o tratamento de distúrbios metabólicos. | |
BRPI0908715A2 (pt) | métodos para tratamento da psoríase | |
BRPI0922884A2 (pt) | compostos para tratamento de câncer | |
FI20085693A0 (fi) | Biosignaalin prosessointi | |
DK2271618T3 (da) | Farmaceutiske forbindelser | |
SMT201600156B (it) | Trattamento dell’osteoartrite | |
DK2501381T3 (da) | Behandling af atrieflimmer | |
BRPI0912043A2 (pt) | métodos de tratamento de doença associada à cinesina meiótica | |
BRPI0915761A2 (pt) | composto de heterociclila para tratamento de doença cardiovascular | |
BRPI0920728A2 (pt) | Composição estabilizada para tratamento de psoríase | |
DK2173197T3 (da) | Fremgangsmåde | |
CU23884B1 (es) | Derivados de dibenzotiazepina | |
BRPI0908497A2 (pt) | métodos e composições para um rendimento aumentado |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2376 DE 19-07-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |