BRPI0913843A2 - processo de granulação por fusão - Google Patents
processo de granulação por fusãoInfo
- Publication number
- BRPI0913843A2 BRPI0913843A2 BRPI0913843A BRPI0913843A BRPI0913843A2 BR PI0913843 A2 BRPI0913843 A2 BR PI0913843A2 BR PI0913843 A BRPI0913843 A BR PI0913843A BR PI0913843 A BRPI0913843 A BR PI0913843A BR PI0913843 A2 BRPI0913843 A2 BR PI0913843A2
- Authority
- BR
- Brazil
- Prior art keywords
- granulation process
- melt granulation
- melt
- granulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13385108P | 2008-07-03 | 2008-07-03 | |
PCT/US2009/049548 WO2010003078A2 (en) | 2008-07-03 | 2009-07-02 | Melt granulation process |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0913843A2 true BRPI0913843A2 (pt) | 2015-10-20 |
Family
ID=41328880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0913843A BRPI0913843A2 (pt) | 2008-07-03 | 2009-07-02 | processo de granulação por fusão |
Country Status (14)
Country | Link |
---|---|
US (1) | US20110092515A1 (pt) |
EP (1) | EP2309987B1 (pt) |
JP (1) | JP2011526928A (pt) |
KR (1) | KR20110031485A (pt) |
CN (1) | CN102076329B (pt) |
AU (1) | AU2009266833B2 (pt) |
BR (1) | BRPI0913843A2 (pt) |
CA (1) | CA2729596A1 (pt) |
ES (1) | ES2393949T3 (pt) |
MX (1) | MX2010014566A (pt) |
PL (1) | PL2309987T3 (pt) |
PT (1) | PT2309987E (pt) |
RU (1) | RU2491918C2 (pt) |
WO (1) | WO2010003078A2 (pt) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102005005449A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
BRPI0906467C1 (pt) | 2008-01-25 | 2021-05-25 | Gruenenthal Gmbh | forma de dosagem farmacêutica com formato exterior modificado resistente à ruptura e com liberação controlada |
CA2723438C (en) | 2008-05-09 | 2016-10-11 | Gruenenthal Gmbh | Process for the preparation of an intermediate powder formulation and a final solid dosage form under usage of a spray congealing step |
JP5667183B2 (ja) | 2009-07-22 | 2015-02-12 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 加熱溶融押出成型した制御放出性投与剤型 |
CN102639118B (zh) | 2009-07-22 | 2015-07-29 | 格吕伦塔尔有限公司 | 氧化稳定的抗干扰剂型 |
WO2011095314A2 (en) * | 2010-02-03 | 2011-08-11 | Grünenthal GmbH | Preparation of a powdery pharmaceutical composition by means of an extruder |
TWI516286B (zh) | 2010-09-02 | 2016-01-11 | 歌林達股份有限公司 | 含陰離子聚合物之抗破碎劑型 |
CN103269688A (zh) | 2010-09-02 | 2013-08-28 | 格吕伦塔尔有限公司 | 包含无机盐的抗破碎剂型 |
NO2736495T3 (pt) | 2011-07-29 | 2018-01-20 | ||
WO2013017242A1 (en) | 2011-07-29 | 2013-02-07 | Grünenthal GmbH | Tamper-resistant tablet providing immediate drug release |
BR112014019988A8 (pt) | 2012-02-28 | 2017-07-11 | Gruenenthal Gmbh | Forma de dosagem resistente a socamento compreendendo um composto farmacologicamente ativo e um polímero aniônico |
AR090695A1 (es) | 2012-04-18 | 2014-12-03 | Gruenenthal Gmbh | Forma de dosificacion farmaceutica resistente a la adulteracion y resistente a la liberacion inmediata de la dosis |
US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
GB2502080A (en) * | 2012-05-15 | 2013-11-20 | Univ Bradford | Preparation of metastable polymorphs of active pharmaceutical ingredients |
US9395468B2 (en) | 2012-08-27 | 2016-07-19 | Ocular Dynamics, Llc | Contact lens with a hydrophilic layer |
IN2013CH02295A (pt) * | 2013-05-27 | 2015-10-02 | Steer Engineering Private Ltd | |
AU2014273227B2 (en) | 2013-05-29 | 2019-08-15 | Grunenthal Gmbh | Tamper-resistant dosage form containing one or more particles |
MX2015016254A (es) | 2013-05-29 | 2016-04-20 | Gruenenthal Gmbh | Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal. |
KR20160031526A (ko) | 2013-07-12 | 2016-03-22 | 그뤼넨탈 게엠베하 | 에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형 |
AU2014348502B2 (en) | 2013-11-15 | 2019-08-15 | Tangible Science, Inc. | Contact lens with a hydrophilic layer |
JP6480936B2 (ja) | 2013-11-26 | 2019-03-13 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | クライオミリングによる粉末状医薬組成物の調製 |
MX2016014738A (es) | 2014-05-12 | 2017-03-06 | Gruenenthal Gmbh | Formulacion en capsula de liberacion inmediata resistente a alteraciones que comprende tapentadol. |
EA201692388A1 (ru) | 2014-05-26 | 2017-05-31 | Грюненталь Гмбх | Лекарственная форма в виде множества частиц, защищенная от вызываемого этанолом сброса дозы |
CA2970010A1 (en) | 2014-12-09 | 2016-06-16 | Karen Havenstrite | Medical device coating with a biocompatible layer |
EA035434B1 (ru) | 2015-04-24 | 2020-06-15 | Грюненталь Гмбх | Защищенная от применения не по назначению лекарственная форма с немедленным высвобождением и устойчивостью к экстракции растворителями |
CA2998259A1 (en) | 2015-09-10 | 2017-03-16 | Grunenthal Gmbh | Protecting oral overdose with abuse deterrent immediate release formulations |
US10342886B2 (en) | 2016-01-26 | 2019-07-09 | S.C. Johnson & Son, Inc. | Extruded wax melt and method of producing same |
US10010638B2 (en) | 2016-06-14 | 2018-07-03 | S. C. Johnson & Son, Inc. | Wax melt with filler |
KR102530612B1 (ko) * | 2020-08-21 | 2023-05-09 | 한국휴텍스제약 주식회사 | 자가과립화 기법을 이용한 딜티아젬 서방정 조성물의 제조방법 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
DE19504832A1 (de) * | 1995-02-14 | 1996-08-22 | Basf Ag | Feste Wirkstoff-Zubereitungen |
HN1998000115A (es) * | 1997-08-21 | 1999-06-02 | Warner Lambert Co | Formas de dosificación farmacéuticas sólidas |
BRPI0507891A (pt) * | 2004-02-20 | 2007-07-24 | Chiron Corp | modulação dos processos inflamatório e metastático |
CN101166517B (zh) * | 2005-05-10 | 2012-01-04 | 诺瓦提斯公司 | 制备含有可压性差的治疗性化合物的组合物的挤压方法 |
JP5400377B2 (ja) * | 2005-05-10 | 2014-01-29 | ノバルティス アーゲー | 圧縮性に乏しい治療用化合物を有する組成物の製造法 |
CN102070614B (zh) * | 2005-05-23 | 2014-01-15 | 诺华股份有限公司 | 4-氨基-5-氟-3-[6-(4-甲基哌嗪-1-基)-1h-苯并咪唑-2-基]-1h-喹啉-2-酮乳酸盐的结晶和其它形式 |
CN101316593B (zh) * | 2005-11-29 | 2012-05-02 | 诺瓦提斯公司 | 喹啉酮类的制剂 |
MY148529A (en) * | 2005-11-29 | 2013-04-30 | Novartis Ag | Formulations of quinolinones |
-
2009
- 2009-07-02 PT PT97745277T patent/PT2309987E/pt unknown
- 2009-07-02 KR KR1020117002593A patent/KR20110031485A/ko not_active Application Discontinuation
- 2009-07-02 JP JP2011516879A patent/JP2011526928A/ja active Pending
- 2009-07-02 ES ES09774527T patent/ES2393949T3/es active Active
- 2009-07-02 CA CA2729596A patent/CA2729596A1/en not_active Abandoned
- 2009-07-02 US US13/000,044 patent/US20110092515A1/en not_active Abandoned
- 2009-07-02 RU RU2011103651/15A patent/RU2491918C2/ru not_active IP Right Cessation
- 2009-07-02 PL PL09774527T patent/PL2309987T3/pl unknown
- 2009-07-02 CN CN200980125276XA patent/CN102076329B/zh not_active Expired - Fee Related
- 2009-07-02 AU AU2009266833A patent/AU2009266833B2/en not_active Ceased
- 2009-07-02 BR BRPI0913843A patent/BRPI0913843A2/pt not_active IP Right Cessation
- 2009-07-02 MX MX2010014566A patent/MX2010014566A/es active IP Right Grant
- 2009-07-02 EP EP09774527A patent/EP2309987B1/en not_active Not-in-force
- 2009-07-02 WO PCT/US2009/049548 patent/WO2010003078A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
EP2309987A2 (en) | 2011-04-20 |
WO2010003078A2 (en) | 2010-01-07 |
CA2729596A1 (en) | 2010-01-07 |
PL2309987T3 (pl) | 2013-01-31 |
PT2309987E (pt) | 2012-12-13 |
RU2491918C2 (ru) | 2013-09-10 |
CN102076329A (zh) | 2011-05-25 |
AU2009266833A1 (en) | 2010-01-07 |
KR20110031485A (ko) | 2011-03-28 |
AU2009266833B2 (en) | 2013-01-31 |
US20110092515A1 (en) | 2011-04-21 |
JP2011526928A (ja) | 2011-10-20 |
EP2309987B1 (en) | 2012-08-29 |
CN102076329B (zh) | 2013-03-06 |
WO2010003078A3 (en) | 2010-05-27 |
ES2393949T3 (es) | 2013-01-02 |
RU2011103651A (ru) | 2012-08-10 |
MX2010014566A (es) | 2011-02-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BRPI0913843A2 (pt) | processo de granulação por fusão | |
BRPI0821944A2 (pt) | Processo | |
BRPI0919868A2 (pt) | processo | |
SMT201400100B (it) | Processo migliorato | |
BRPI1011689A2 (pt) | processo de autofocalização e conjunto de autofocalização | |
BRPI0910689A2 (pt) | processo de síntese de rna por via química | |
BR112012000821A2 (pt) | "processo" | |
BRPI1007829A2 (pt) | processo de separação | |
BRPI0914675A2 (pt) | processo de secagem por atomização | |
BRPI0914670A2 (pt) | processo de secagem por atomização | |
BR112012000822A2 (pt) | processo | |
BR112012012338A2 (pt) | processo | |
BRPI0815412A2 (pt) | Processo de sedimentação por coagulação | |
BRPI0921374A2 (pt) | processo | |
BRPI0718075A2 (pt) | Processo de hidrogenação | |
BRPI1010093A2 (pt) | processo de polimerização em solução | |
BRPI0806503A2 (pt) | Processo aperfeiçoado de secagem por pulverização | |
BRPI1008300A2 (pt) | processo de purificação de daptomicina | |
BRPI0806679A2 (pt) | Processo aperfeiçoado de produção de alquilaromático | |
BR112012014943A2 (pt) | processo de secagem por atomização | |
BRPI1012134A2 (pt) | processo de carbolinação | |
BRPI1009095A2 (pt) | processo de secagem por atomização | |
BRPI0922821A2 (pt) | processo de fabricação de micropartículas de liberação sustentada | |
BRPI0913962A2 (pt) | processo de secagem por atomização | |
BRPI1010553A2 (pt) | processo de carbonilação. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application fees: application dismissed [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |