BRPI0817792A2 - Uso de uma sequência codificadora do domínio carbóxi-terminal da subunidade pesada da toxina tetânica como medicamento - Google Patents
Uso de uma sequência codificadora do domínio carbóxi-terminal da subunidade pesada da toxina tetânica como medicamentoInfo
- Publication number
- BRPI0817792A2 BRPI0817792A2 BRPI0817792A BRPI0817792A2 BR PI0817792 A2 BRPI0817792 A2 BR PI0817792A2 BR PI0817792 A BRPI0817792 A BR PI0817792A BR PI0817792 A2 BRPI0817792 A2 BR PI0817792A2
- Authority
- BR
- Brazil
- Prior art keywords
- medicament
- coding sequence
- terminal domain
- tetanus toxin
- domain coding
- Prior art date
Links
- 108091026890 Coding region Proteins 0.000 title 1
- 108010055044 Tetanus Toxin Proteins 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940118376 tetanus toxin Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10041—Use of virus, viral particle or viral elements as a vector
- C12N2710/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10071—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16141—Use of virus, viral particle or viral elements as a vector
- C12N2710/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16171—Demonstrated in vivo effect
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/00041—Use of virus, viral particle or viral elements as a vector
- C12N2740/00043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/00071—Demonstrated in vivo effect
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200702621A ES2332628B1 (es) | 2007-10-05 | 2007-10-05 | Uso de la secuencia codificante del dominio carboxilo terminal de la cadena pesada de la toxina tetanica como medicamento. |
PCT/ES2008/070186 WO2009043963A1 (es) | 2007-10-05 | 2008-10-03 | Uso de la secuencia codificante del dominio carboxilo terminal de la cadena pesada de la toxina tetánica como medicamento |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0817792A2 true BRPI0817792A2 (pt) | 2015-03-24 |
Family
ID=40525852
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0817792 BRPI0817792A2 (pt) | 2007-10-05 | 2008-10-03 | Uso de uma sequência codificadora do domínio carbóxi-terminal da subunidade pesada da toxina tetânica como medicamento |
Country Status (10)
Country | Link |
---|---|
US (2) | US8945586B2 (pt) |
EP (1) | EP2210611B1 (pt) |
JP (1) | JP5325224B2 (pt) |
CN (1) | CN101873865B (pt) |
BR (1) | BRPI0817792A2 (pt) |
CA (1) | CA2701521C (pt) |
ES (2) | ES2332628B1 (pt) |
MX (1) | MX2010003695A (pt) |
RU (1) | RU2495676C2 (pt) |
WO (1) | WO2009043963A1 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2332628B1 (es) | 2007-10-05 | 2011-01-24 | Universidad De Zaragoza | Uso de la secuencia codificante del dominio carboxilo terminal de la cadena pesada de la toxina tetanica como medicamento. |
JP2017521408A (ja) * | 2014-07-02 | 2017-08-03 | スフェリウム バイオメッド エス.エル. | 無毒性破傷風毒素cフラグメント(ttc)を使用して筋量を増加させる方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2498192A2 (fr) | 1981-01-22 | 1982-07-23 | Pasteur Institut | Nouveau compose polypeptidique thiole provenant d'un fragment de la toxine tetanique, son procede d'obtention et ses applications |
US7923216B2 (en) * | 1997-08-14 | 2011-04-12 | Institut Pasteur | In vivo modulation of neuronal transport |
PT1049712E (pt) * | 1997-08-14 | 2007-04-30 | Pasteur Institut | Proteínas híbridas da toxina do tétano que migram retrogradamente e trans - sinapticamente para o snc |
US7494661B2 (en) * | 2000-06-28 | 2009-02-24 | Ira Sanders | Methods for using tetanus toxin for beneficial purposes in animals (mammals) |
AU2003268484A1 (en) * | 2002-09-06 | 2004-03-29 | The General Hospital Corporation | Delivery of therapeutics to the brain and spinal cord |
ES2281278B1 (es) * | 2006-01-20 | 2008-10-16 | Universidad Autonoma De Barcelona | Empleo de un polipeptido que comprende el dominio c-terminal de la cadena pesada de la toxina tetanica en el tratamiento del parkinsonismo. |
WO2008094583A2 (en) * | 2007-01-30 | 2008-08-07 | The General Hospital Corporation | Methods and devices for mri-based measurement of axonal transport in vivo and delivery of therapeutic substances to the cns |
ES2332628B1 (es) | 2007-10-05 | 2011-01-24 | Universidad De Zaragoza | Uso de la secuencia codificante del dominio carboxilo terminal de la cadena pesada de la toxina tetanica como medicamento. |
-
2007
- 2007-10-05 ES ES200702621A patent/ES2332628B1/es active Active
-
2008
- 2008-10-03 WO PCT/ES2008/070186 patent/WO2009043963A1/es active Application Filing
- 2008-10-03 BR BRPI0817792 patent/BRPI0817792A2/pt not_active IP Right Cessation
- 2008-10-03 JP JP2010527478A patent/JP5325224B2/ja not_active Expired - Fee Related
- 2008-10-03 EP EP08836703.2A patent/EP2210611B1/en active Active
- 2008-10-03 CN CN2008801173975A patent/CN101873865B/zh not_active Expired - Fee Related
- 2008-10-03 ES ES08836703.2T patent/ES2463770T3/es active Active
- 2008-10-03 CA CA2701521A patent/CA2701521C/en not_active Expired - Fee Related
- 2008-10-03 MX MX2010003695A patent/MX2010003695A/es active IP Right Grant
- 2008-10-03 RU RU2010115135/15A patent/RU2495676C2/ru not_active IP Right Cessation
-
2010
- 2010-04-05 US US12/754,552 patent/US8945586B2/en not_active Expired - Fee Related
-
2014
- 2014-12-15 US US14/570,976 patent/US20160017008A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO2009043963A1 (es) | 2009-04-09 |
US20160017008A1 (en) | 2016-01-21 |
CA2701521C (en) | 2015-12-01 |
EP2210611A1 (en) | 2010-07-28 |
US20100261656A1 (en) | 2010-10-14 |
CN101873865A (zh) | 2010-10-27 |
RU2010115135A (ru) | 2011-11-10 |
JP5325224B2 (ja) | 2013-10-23 |
CN101873865B (zh) | 2013-06-05 |
CA2701521A1 (en) | 2009-04-09 |
JP2010540599A (ja) | 2010-12-24 |
ES2332628B1 (es) | 2011-01-24 |
EP2210611A4 (en) | 2010-12-15 |
ES2463770T3 (es) | 2014-05-29 |
US8945586B2 (en) | 2015-02-03 |
ES2332628A1 (es) | 2010-02-09 |
MX2010003695A (es) | 2010-09-14 |
EP2210611B1 (en) | 2014-02-26 |
RU2495676C2 (ru) | 2013-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |