BRPI0817444A2 - Prímeres de poliunucleotídeo - Google Patents

Prímeres de poliunucleotídeo

Info

Publication number
BRPI0817444A2
BRPI0817444A2 BRPI0817444-0A BRPI0817444A BRPI0817444A2 BR PI0817444 A2 BRPI0817444 A2 BR PI0817444A2 BR PI0817444 A BRPI0817444 A BR PI0817444A BR PI0817444 A2 BRPI0817444 A2 BR PI0817444A2
Authority
BR
Brazil
Prior art keywords
polyunucleotide
primers
polyunucleotide primers
Prior art date
Application number
BRPI0817444-0A
Other languages
English (en)
Inventor
Ruth Board
Jennifer Ferguson
Paul Francis Ravetto
Nicola Jo Thelwell
David Whitcombe
Original Assignee
Dxs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dxs Ltd filed Critical Dxs Ltd
Publication of BRPI0817444A2 publication Critical patent/BRPI0817444A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0817444-0A 2007-09-28 2008-09-29 Prímeres de poliunucleotídeo BRPI0817444A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0719034A GB2453173A (en) 2007-09-28 2007-09-28 Polynucleotide primers
PCT/GB2008/003306 WO2009040557A2 (en) 2007-09-28 2008-09-29 Polynucleotide primers for detecting pik3ca mutations

Publications (1)

Publication Number Publication Date
BRPI0817444A2 true BRPI0817444A2 (pt) 2015-06-16

Family

ID=38701889

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0817444-0A BRPI0817444A2 (pt) 2007-09-28 2008-09-29 Prímeres de poliunucleotídeo

Country Status (13)

Country Link
US (4) US8901285B2 (pt)
EP (7) EP2505672B1 (pt)
JP (1) JP5719593B2 (pt)
KR (4) KR101543214B1 (pt)
CN (4) CN103834724B (pt)
AU (1) AU2008303400B2 (pt)
BR (1) BRPI0817444A2 (pt)
CA (2) CA3010064A1 (pt)
ES (6) ES2531055T3 (pt)
GB (1) GB2453173A (pt)
MX (1) MX2010003486A (pt)
RU (1) RU2491289C2 (pt)
WO (1) WO2009040557A2 (pt)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10190171B2 (en) 2007-09-28 2019-01-29 Qiagen Manchester Limited Polynucleotide primers for detecting PIK3CA mutations

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EP3246332B1 (en) 2010-01-12 2019-07-10 Siemens Healthcare Diagnostics Inc. Oligonucleotides and methods for detecting pik3ca mutations
JP2013081450A (ja) * 2011-09-27 2013-05-09 Arkray Inc 多型検出用プローブ、多型検出方法、薬効判定方法及び多型検出用試薬キット
CN102453765B (zh) * 2011-11-03 2013-07-24 厦门艾德生物医药科技有限公司 Pik3ca基因驱动突变的检测探针、引物及试剂盒
NZ628596A (en) 2012-03-29 2015-10-30 Novartis Ag Pharmaceutical diagnostics for treatment of cancer in subjects having pi3k mutation
CN102816839A (zh) * 2012-07-06 2012-12-12 杭州艾迪康医学检验中心有限公司 用于检测结直肠癌pik3ca基因热点突变位点的试剂盒
EP2711432A1 (en) * 2012-09-21 2014-03-26 Genomica S.A.U. Method for detection of BRAF and PI3K mutations
US20140272961A1 (en) * 2013-03-13 2014-09-18 Roche Molecular Systems, Inc. Methods and compositions for detecting mutations in the human pi3kca (pik3ca) gene
CN103773837A (zh) * 2013-06-25 2014-05-07 宁波有成生物医药科技有限公司 一种pik3ca基因突变荧光定量pcr检测试剂盒及检测方法
RU2549682C1 (ru) * 2013-10-21 2015-04-27 Общество с ограниченной ответственностью "БИОЧИП-ИМБ" Способ анализа соматических мутаций в гене pi3k с использованием lna-блокирующей мультиплексной пцр и последующей гибридизацией с олигонуклеотидным биологическим микрочипом (биочипом)
US20170044622A1 (en) 2014-04-18 2017-02-16 Blueprint Medicines Corporation Pik3ca fusions
CN105274188A (zh) * 2014-05-29 2016-01-27 北京雅康博生物科技有限公司 Pik3ca基因突变检测试剂盒
JP6770957B2 (ja) * 2014-08-07 2020-10-21 ファーマシスト リミテッドＰｈａｒｍａｓｓｉｓｔ Ｌｔｄ 試料中のｐｉｋ３ｃａ突然変異状態を決定する方法
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CN105441533B (zh) * 2014-11-29 2019-07-05 上海赛安生物医药科技有限公司 Pik3ca基因突变检测体系及其试剂盒
CN104531875A (zh) * 2014-12-30 2015-04-22 宁波有成生物医药科技有限公司 一种MyD88基因突变荧光定量PCR检测试剂盒及检测方法

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10190171B2 (en) 2007-09-28 2019-01-29 Qiagen Manchester Limited Polynucleotide primers for detecting PIK3CA mutations
US10196692B2 (en) 2007-09-28 2019-02-05 Qiagen Manchester Limited Polynucleotide primers for detecting PIK3CA mutations

Also Published As

Publication number Publication date
US20110027779A1 (en) 2011-02-03
KR101543216B1 (ko) 2015-08-07
WO2009040557A3 (en) 2009-05-14
US20160032408A1 (en) 2016-02-04
US20140141425A1 (en) 2014-05-22
ES2532141T3 (es) 2015-03-24
EP2205760A2 (en) 2010-07-14
CA2700710A1 (en) 2009-04-02
AU2008303400B2 (en) 2013-09-26
EP2505672B1 (en) 2015-01-14
AU2008303400A1 (en) 2009-04-02
EP2236627B1 (en) 2015-01-14
EP2508624B1 (en) 2015-01-14
KR101543215B1 (ko) 2015-08-07
US10196692B2 (en) 2019-02-05
EP2505672A1 (en) 2012-10-03
EP2239341B1 (en) 2015-01-14
US10190171B2 (en) 2019-01-29
CN103834724B (zh) 2016-05-25
GB2453173A (en) 2009-04-01
CN103834724A (zh) 2014-06-04
CN103695558B (zh) 2016-01-20
US20160040255A1 (en) 2016-02-11
CN102119222B (zh) 2015-11-25
MX2010003486A (es) 2010-08-09
US8901285B2 (en) 2014-12-02
EP2505671B1 (en) 2017-02-01
EP2505673B1 (en) 2017-02-01
JP2010539920A (ja) 2010-12-24
CN102119222A (zh) 2011-07-06
JP5719593B2 (ja) 2015-05-20
ES2532225T3 (es) 2015-03-25
ES2620289T3 (es) 2017-06-28
ES2531055T3 (es) 2015-03-10
EP2239341A1 (en) 2010-10-13
RU2010116772A (ru) 2011-11-10
US9863003B2 (en) 2018-01-09
ES2622885T3 (es) 2017-07-07
EP2239341A8 (en) 2010-12-01
RU2491289C2 (ru) 2013-08-27
EP2236627A1 (en) 2010-10-06
CN103952466B (zh) 2016-07-06
EP2505673A1 (en) 2012-10-03
WO2009040557A2 (en) 2009-04-02
KR20150038661A (ko) 2015-04-08
KR20150038659A (ko) 2015-04-08
CA2700710C (en) 2018-08-21
EP2505671A1 (en) 2012-10-03
EP2205760B1 (en) 2012-06-27
KR101548758B1 (ko) 2015-09-01
KR20100101070A (ko) 2010-09-16
EP2236627A8 (en) 2010-12-01
KR101543214B1 (ko) 2015-08-07
CN103952466A (zh) 2014-07-30
KR20150038660A (ko) 2015-04-08
GB0719034D0 (en) 2007-11-07
CN103695558A (zh) 2014-04-02
EP2508624A1 (en) 2012-10-10
CA3010064A1 (en) 2009-04-02
ES2531994T3 (es) 2015-03-23

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