BRPI0812942A2 - Composto, composição farmacêutica e uso de um composto - Google Patents

Composto, composição farmacêutica e uso de um composto

Info

Publication number
BRPI0812942A2
BRPI0812942A2 BRPI0812942-8A2A BRPI0812942A BRPI0812942A2 BR PI0812942 A2 BRPI0812942 A2 BR PI0812942A2 BR PI0812942 A BRPI0812942 A BR PI0812942A BR PI0812942 A2 BRPI0812942 A2 BR PI0812942A2
Authority
BR
Brazil
Prior art keywords
compound
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
BRPI0812942-8A2A
Other languages
English (en)
Inventor
Christian Hubschwerlen
Georg Rueedi
Jean-Philippe Surivet
Cornelia Zumbrunn-Acklin
Original Assignee
Actelion Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd
Publication of BRPI0812942A2 publication Critical patent/BRPI0812942A2/pt
Publication of BRPI0812942A8 publication Critical patent/BRPI0812942A8/pt
Publication of BRPI0812942B1 publication Critical patent/BRPI0812942B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
BRPI0812942A 2007-06-15 2008-06-13 composto derivado de 3-amino-6 - (1-amino-etil) - tetra-hidropirano, composição farmacêutica e uso de referido composto. BRPI0812942B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IB2007052301 2007-06-15
PCT/IB2008/052333 WO2008152603A1 (en) 2007-06-15 2008-06-13 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives

Publications (3)

Publication Number Publication Date
BRPI0812942A2 true BRPI0812942A2 (pt) 2014-12-16
BRPI0812942A8 BRPI0812942A8 (pt) 2018-05-02
BRPI0812942B1 BRPI0812942B1 (pt) 2018-11-21

Family

ID=39772866

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0812942A BRPI0812942B1 (pt) 2007-06-15 2008-06-13 composto derivado de 3-amino-6 - (1-amino-etil) - tetra-hidropirano, composição farmacêutica e uso de referido composto.

Country Status (15)

Country Link
US (1) US8193179B2 (pt)
EP (1) EP2167494B1 (pt)
JP (1) JP5274553B2 (pt)
KR (1) KR101538814B1 (pt)
CN (1) CN101711243B (pt)
AR (1) AR067008A1 (pt)
AT (1) ATE520687T1 (pt)
AU (1) AU2008263397B2 (pt)
BR (1) BRPI0812942B1 (pt)
CA (1) CA2689102C (pt)
ES (1) ES2370123T3 (pt)
MX (1) MX2009013254A (pt)
PL (1) PL2167494T3 (pt)
TW (1) TWI414290B (pt)
WO (1) WO2008152603A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009215327A1 (en) 2008-02-20 2009-08-27 Actelion Pharmaceuticals Ltd Azatricyclic antibiotic compounds
CN102046603B (zh) * 2008-06-03 2014-08-13 埃科特莱茵药品有限公司 作为抗细菌剂的[4-(1-氨基-乙基)-环己基]-甲基-胺及[6-(1-氨基-乙基)-四氢-吡喃-3-基]-甲基-胺衍生物
CN104151316B (zh) 2008-10-07 2016-06-15 埃科特莱茵药品有限公司 三环噁唑烷酮抗生素化合物
SG172088A1 (en) * 2008-12-12 2011-07-28 Actelion Pharmaceuticals Ltd 5-amino-2-(1-hydroxy-ethyl)-tetrahydropyran derivatives
EP2748163B1 (en) 2011-05-31 2016-04-20 Actelion Pharmaceuticals Ltd. Process for preparing synthetic intermediates which can be used for manufacturing antibiotics
AU2012275499A1 (en) * 2011-06-27 2013-12-19 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
CN106083787B (zh) * 2016-06-21 2018-05-04 济南川成医药科技开发有限公司 一种4-(2-氨乙基)四氢吡喃的合成方法
WO2018026877A1 (en) 2016-08-05 2018-02-08 Calitor Sciences, Llc Process for preparing substituted quinolin-4-ol compounds
TW201833120A (zh) 2017-02-17 2018-09-16 瑞士商愛杜西亞製藥有限公司 芳基噁唑啶酮抗生素化合物
EP3665156A4 (en) 2017-08-09 2021-04-28 Denali Therapeutics Inc. COMPOUNDS, COMPOSITIONS, AND PROCEDURES
PL3676297T3 (pl) * 2017-09-01 2023-12-11 Denali Therapeutics Inc. Związki, kompozycje i sposoby
CN113518618A (zh) 2019-02-13 2021-10-19 戴纳立制药公司 化合物、组合物及方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816618B1 (fr) 2000-11-15 2002-12-27 Aventis Pharma Sa Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
EP2239260A1 (de) * 2002-10-10 2010-10-13 Morphochem Aktiengesellschaft Für Kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
EP1778688A1 (en) * 2004-07-22 2007-05-02 Glaxo Group Limited Antibacterial agents
DE102004041163A1 (de) * 2004-08-25 2006-03-02 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen mit antibakterieller Aktivität
JP4887297B2 (ja) * 2004-09-24 2012-02-29 アクテリオン ファーマシューティカルズ リミテッド 新規二環式抗生物質
JP5314244B2 (ja) 2004-10-27 2013-10-16 富山化学工業株式会社 新規な含窒素複素環化合物およびその塩
CN101258157A (zh) 2005-05-24 2008-09-03 阿斯利康(瑞典)有限公司 具有抗菌活性的氨基哌啶喹啉及其氮杂等构类似物
EP1981881B1 (en) * 2006-01-26 2011-12-07 Actelion Pharmaceuticals Ltd. Tetrahydropyrane antibiotics
WO2007105154A2 (en) * 2006-03-10 2007-09-20 Actelion Pharmaceuticals Ltd Antibiotic compounds

Also Published As

Publication number Publication date
BRPI0812942B1 (pt) 2018-11-21
PL2167494T3 (pl) 2012-01-31
JP5274553B2 (ja) 2013-08-28
EP2167494B1 (en) 2011-08-17
JP2010529983A (ja) 2010-09-02
MX2009013254A (es) 2010-01-25
TWI414290B (zh) 2013-11-11
ATE520687T1 (de) 2011-09-15
US20100179135A1 (en) 2010-07-15
RU2010101003A (ru) 2011-07-20
BRPI0812942A8 (pt) 2018-05-02
KR20100023031A (ko) 2010-03-03
CN101711243B (zh) 2013-01-09
US8193179B2 (en) 2012-06-05
CN101711243A (zh) 2010-05-19
CA2689102A1 (en) 2008-12-18
AU2008263397A1 (en) 2008-12-18
EP2167494A1 (en) 2010-03-31
ES2370123T3 (es) 2011-12-12
CA2689102C (en) 2016-07-26
TW200906416A (en) 2009-02-16
AR067008A1 (es) 2009-09-30
AU2008263397B2 (en) 2013-12-05
KR101538814B1 (ko) 2015-07-22
WO2008152603A1 (en) 2008-12-18

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B25L Entry of change of name and/or headquarter and transfer of application, patent and certificate of addition of invention: publication cancelled

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B25C Requirement related to requested transfer of rights

Owner name: ACTELION PHARMACEUTICALS LTD (CH)

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B25A Requested transfer of rights approved

Owner name: IDORSIA PHARMACEUTICALS LTD (CH)

B06I Publication of requirement cancelled [chapter 6.9 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 21/11/2018, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2594 DE 24-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.