BRPI0810096A2 - Anticorpo anti-epcam e seus usos - Google Patents

Anticorpo anti-epcam e seus usos

Info

Publication number: BRPI0810096A2
Authority: BR; Brazil
Prior art keywords: epcam antibody; therapeutic; designated; high affinity; shows high
Prior art date: 2007-04-04

Application number

BRPI0810096-9A2A

Other languages

English (en)

Inventor

Anna Maria Anastasi

Fiorella Petronzelli

Rita De Santis

Saverio Alberti

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-04-04

Filing date

2008-04-02

Publication date

2014-10-21

2008-04-02 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

2014-10-21 Publication of BRPI0810096A2 publication Critical patent/BRPI0810096A2/pt

2017-12-26 Publication of BRPI0810096A8 publication Critical patent/BRPI0810096A8/pt

Links

206010028980 Neoplasm Diseases 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

BRPI0810096A 2007-04-04 2008-04-02 Anticorpo anti-epcam e seus usos BRPI0810096A8 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP07105628		2007-04-04
PCT/EP2008/053913 WO2008122551A2 (en)	2007-04-04	2008-04-02	Anti-epcam antibody and uses thereof

Publications (2)

Publication Number	Publication Date
BRPI0810096A2 true BRPI0810096A2 (pt)	2014-10-21
BRPI0810096A8 BRPI0810096A8 (pt)	2017-12-26

Family

ID=38458122

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0810096A BRPI0810096A8 (pt)	2007-04-04	2008-04-02	Anticorpo anti-epcam e seus usos

Country Status (21)

Country	Link
US (1)	US8318911B2 (pt)
EP (1)	EP2142570B1 (pt)
JP (1)	JP5631733B2 (pt)
KR (1)	KR101683884B1 (pt)
CN (1)	CN101970497B (pt)
AT (1)	ATE512988T1 (pt)
AU (1)	AU2008235566B2 (pt)
BR (1)	BRPI0810096A8 (pt)
CA (1)	CA2682296C (pt)
CY (1)	CY1111819T1 (pt)
DK (1)	DK2142570T3 (pt)
EA (1)	EA023679B1 (pt)
ES (1)	ES2367675T3 (pt)
HR (1)	HRP20110620T1 (pt)
IL (1)	IL201196A0 (pt)
MX (1)	MX2009010444A (pt)
PL (1)	PL2142570T3 (pt)
PT (1)	PT2142570E (pt)
RS (1)	RS52040B (pt)
SI (1)	SI2142570T1 (pt)
WO (1)	WO2008122551A2 (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1585974B1 (en)	2003-01-24	2013-02-27	University of Utah	Methods of predicting mortality risk by determining telomere length
AU2009329987B2 (en)	2008-12-22	2016-08-04	University Of Utah Research Foundation	Monochrome multiplex quantitative PCR
GB0909904D0 (en) *	2009-06-09	2009-07-22	Affitech As	Product
JP6130307B2 (ja)	2011-03-17	2017-05-17	ザユニバーシティオブバーミンガム	再指向性免疫療法
CN110763842A (zh) *	2011-06-29	2020-02-07	中央研究院	使用表面涂层对生物物质的捕获、纯化和释放
EP2819695B1 (en) *	2012-03-02	2018-06-27	Academia Sinica	ANTI-EPITHELIAL CELL ADHESION MOLECULE (EpCAM) ANTIBODIES AND METHODS OF USE THEREOF
US9494500B2 (en)	2012-10-29	2016-11-15	Academia Sinica	Collection and concentration system for biologic substance of interest and use thereof
CA2912216A1 (en)	2013-05-22	2014-11-27	Telomere Diagnostics, Inc.	Measures of short telomere abundance
TW201623605A (zh)	2014-04-01	2016-07-01	中央研究院	用於癌症診斷及預後之方法及系統
US10112198B2 (en)	2014-08-26	2018-10-30	Academia Sinica	Collector architecture layout design
BR112017014116A2 (pt)	2014-12-30	2018-03-06	Telomere Diagnostics Inc	pcr quantitativo multiplex
US11098131B2 (en)	2015-07-31	2021-08-24	Sutro Biopharma, Inc.	Anti-EpCAM antibodies, compositions comprising anti-EpCAM antibodies and methods of making and using anti-EpCAM antibodies
US10107726B2 (en)	2016-03-16	2018-10-23	Cellmax, Ltd.	Collection of suspended cells using a transferable membrane
US11046782B2 (en)	2016-03-30	2021-06-29	Musc Foundation For Research Development	Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination
WO2018019772A1 (en)	2016-07-26	2018-02-01	Tessa Therapeutics Pte. Ltd.	Chimeric antigen receptor
WO2020018964A1 (en)	2018-07-20	2020-01-23	Fred Hutchinson Cancer Research Center	Compositions and methods for controlled expression of antigen-specific receptors
WO2020131697A2 (en)	2018-12-17	2020-06-25	Revitope Limited	Twin immune cell engager
CN113597432B (zh) *	2019-04-22	2023-05-02	江苏恒瑞医药股份有限公司	抗EpCAM抗体及其应用
CN114026127A (zh)	2019-06-11	2022-02-08	生物蛋白有限公司	条件活性抗epcam抗体、抗体片段、其免疫缀合物以及其用途
CN110950959B (zh) *	2020-02-25	2020-07-03	和铂医药(上海)有限责任公司	靶向EpCAM的抗体及其制备和应用
CN112094350B (zh) *	2020-06-01	2024-01-05	普众发现医药科技(上海)有限公司	可应用于肿瘤细胞捕获的小鼠抗细胞表面糖蛋白cd326的单克隆抗体

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4675187A (en)	1983-05-16	1987-06-23	Bristol-Myers Company	BBM-1675, a new antibiotic complex
US5525338A (en)	1992-08-21	1996-06-11	Immunomedics, Inc.	Detection and therapy of lesions with biotin/avidin conjugates
IT1245748B (it)	1990-12-21	1994-10-14	Mini Ricerca Scient Tecnolog	Preparazione includente anticorpi monoclonali biotinilati, avidina e biotina, per la diagnosi di affezioni tumorali e suo impiego
US5578287A (en)	1992-06-09	1996-11-26	Neorx Corporation	Three-step pretargeting methods using improved biotin-active agent
JP3427871B2 (ja) *	1996-06-24	2003-07-22	戸田工業株式会社	コバルト被着型針状磁性酸化鉄粒子粉末
ITRM20010079A1 (it)	2001-02-16	2002-08-16	Sigma Tau Ind Farmaceuti	Amminoderivati della biotina e loro coniugati con chelanti macrociclici.
US20050180979A1 (en)	2004-02-13	2005-08-18	Micromet Ag	Anti-EpCAM immunoglobulins
US7435804B2 (en)	2004-10-19	2008-10-14	Phage Biotechnology, Inc.	Method for obtaining single chain antibodies to human interferon α2b

2008
- 2008-04-02 EP EP08759374A patent/EP2142570B1/en active Active
- 2008-04-02 JP JP2010501503A patent/JP5631733B2/ja not_active Expired - Fee Related
- 2008-04-02 CA CA2682296A patent/CA2682296C/en not_active Expired - Fee Related
- 2008-04-02 RS RS20110388A patent/RS52040B/en unknown
- 2008-04-02 BR BRPI0810096A patent/BRPI0810096A8/pt not_active Application Discontinuation
- 2008-04-02 WO PCT/EP2008/053913 patent/WO2008122551A2/en active Application Filing
- 2008-04-02 CN CN200880015767.4A patent/CN101970497B/zh not_active Expired - Fee Related
- 2008-04-02 AU AU2008235566A patent/AU2008235566B2/en not_active Ceased
- 2008-04-02 AT AT08759374T patent/ATE512988T1/de active
- 2008-04-02 PL PL08759374T patent/PL2142570T3/pl unknown
- 2008-04-02 MX MX2009010444A patent/MX2009010444A/es active IP Right Grant
- 2008-04-02 US US12/594,559 patent/US8318911B2/en active Active
- 2008-04-02 PT PT08759374T patent/PT2142570E/pt unknown
- 2008-04-02 SI SI200830364T patent/SI2142570T1/sl unknown
- 2008-04-02 EA EA200970923A patent/EA023679B1/ru not_active IP Right Cessation
- 2008-04-02 DK DK08759374.5T patent/DK2142570T3/da active
- 2008-04-02 KR KR1020097023099A patent/KR101683884B1/ko active IP Right Grant
- 2008-04-02 ES ES08759374T patent/ES2367675T3/es active Active
2009
- 2009-09-24 IL IL201196A patent/IL201196A0/en active IP Right Grant
2011
- 2011-08-24 HR HR20110620T patent/HRP20110620T1/hr unknown
- 2011-09-06 CY CY20111100854T patent/CY1111819T1/el unknown

Also Published As

Publication number	Publication date
EP2142570A2 (en)	2010-01-13
BRPI0810096A8 (pt)	2017-12-26
CA2682296A1 (en)	2008-10-16
MX2009010444A (es)	2009-10-20
CN101970497A (zh)	2011-02-09
KR101683884B1 (ko)	2016-12-07
WO2008122551A3 (en)	2008-12-04
JP2010523096A (ja)	2010-07-15
CA2682296C (en)	2017-02-28
DK2142570T3 (da)	2011-10-03
EP2142570B1 (en)	2011-06-15
CN101970497B (zh)	2017-05-10
US8318911B2 (en)	2012-11-27
HRP20110620T1 (hr)	2011-09-30
SI2142570T1 (sl)	2012-01-31
RS52040B (en)	2012-04-30
AU2008235566B2 (en)	2013-06-06
ES2367675T3 (es)	2011-11-07
PT2142570E (pt)	2011-09-13
EA200970923A1 (ru)	2010-04-30
WO2008122551A2 (en)	2008-10-16
ATE512988T1 (de)	2011-07-15
PL2142570T3 (pl)	2011-11-30
JP5631733B2 (ja)	2014-11-26
AU2008235566A1 (en)	2008-10-16
US20100092491A1 (en)	2010-04-15
IL201196A0 (en)	2010-05-17
EA023679B1 (ru)	2016-06-30
CY1111819T1 (el)	2015-10-07
KR20100016237A (ko)	2010-02-12
WO2008122551A9 (en)	2009-02-05

Legal Events

Date	Code	Title	Description
2015-10-13	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2017-12-26	B25A	Requested transfer of rights approved	Owner name: ALFASIGMA S.P.A. (IT)
2018-03-20	B07E	Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]	Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI
2018-04-17	B06F	Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
2018-11-06	B07A	Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
2019-08-13	B09B	Patent application refused [chapter 9.2 patent gazette]
2019-10-29	B09B	Patent application refused [chapter 9.2 patent gazette]	Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL
2022-07-12	B350	Update of information on the portal [chapter 15.35 patent gazette]

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