BRPI0806531A2 - Composto, composição farmacêutica, agente terapêutico, e, uso do composto. - Google Patents

Composto, composição farmacêutica, agente terapêutico, e, uso do composto.

Info

Publication number: BRPI0806531A2
Authority: BR; Brazil
Prior art keywords: compound; pharmaceutical composition; therapeutic agent; therapeutic; agent
Prior art date: 2007-01-12

Application number

BRPI0806531-4A2A

Other languages

English (en)

Inventor

Tomoharu Iino

Hideki Jona

Jun Shibata

Tadashi Shimamura

Takeru Yamakawa

Lihu Yang

Original Assignee

Merck & Co Inc

Banyu Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-12

Filing date

2008-01-08

Publication date

2014-04-22

2008-01-08 Application filed by Merck & Co Inc, Banyu Pharma Co Ltd filed Critical Merck & Co Inc

2014-04-22 Publication of BRPI0806531A2 publication Critical patent/BRPI0806531A2/pt

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems

BRPI0806531-4A2A 2007-01-12 2008-01-08 Composto, composição farmacêutica, agente terapêutico, e, uso do composto. BRPI0806531A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US88030207P	2007-01-12	2007-01-12
PCT/US2008/000221 WO2008088688A1 (en)	2007-01-12	2008-01-08	Substituted spirochromanone derivatives as acc inhibitors

Publications (1)

Publication Number	Publication Date
BRPI0806531A2 true BRPI0806531A2 (pt)	2014-04-22

Family

ID=39297859

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0806531-4A2A BRPI0806531A2 (pt)	2007-01-12	2008-01-08	Composto, composição farmacêutica, agente terapêutico, e, uso do composto.

Country Status (28)

Country	Link
US (1)	US8093389B2 (pt)
EP (1)	EP2111406B1 (pt)
JP (1)	JP5319550B2 (pt)
KR (1)	KR20090108022A (pt)
CN (1)	CN101631791B (pt)
AR (1)	AR064824A1 (pt)
AU (1)	AU2008205638B2 (pt)
BR (1)	BRPI0806531A2 (pt)
CA (1)	CA2674573C (pt)
CL (1)	CL2008000067A1 (pt)
CO (1)	CO6190611A2 (pt)
CR (1)	CR10944A (pt)
DO (1)	DOP2009000176A (pt)
EC (1)	ECSP099503A (pt)
GT (1)	GT200900194A (pt)
HK (1)	HK1131136A1 (pt)
HN (1)	HN2009001276A (pt)
MA (1)	MA31108B1 (pt)
MX (1)	MX2009007502A (pt)
NI (1)	NI200900139A (pt)
NZ (1)	NZ577825A (pt)
PE (1)	PE20081559A1 (pt)
RU (1)	RU2009130736A (pt)
SG (1)	SG177977A1 (pt)
TW (1)	TW200836727A (pt)
UA (1)	UA103990C2 (pt)
WO (2)	WO2008088688A1 (pt)
ZA (1)	ZA200904138B (pt)

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NZ564591A (en) *	2005-07-19	2010-01-29	Merck & Co Inc	Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
JP5271917B2 (ja) *	2007-01-12	2013-08-21	メルク・シャープ・アンド・ドーム・コーポレーション	スピロクロマノン誘導体
EP2242745A1 (de) *	2008-02-07	2010-10-27	Sanofi-Aventis	Neue phenyl-substituierte imidazolidine, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8318762B2 (en)	2008-05-28	2012-11-27	Pfizer Inc.	Pyrazolospiroketone acetyl-CoA carboxylase inhibitors
WO2010002010A1 (en)	2008-07-04	2010-01-07	Banyu Pharmaceutical Co.,Ltd.	Novel spirochromanone carboxylic acids
CA2730493A1 (en) *	2008-07-14	2010-01-21	Cropsolution, Inc.	Modulators of acetyl-coenzyme a carboxylase and methods of use thereof
US8653098B2 (en)	2008-11-20	2014-02-18	Genentech, Inc.	Pyrazolopyridine PI3K inhibitor compounds and methods of use
AP3283A (en) *	2009-11-10	2015-05-31	Pfizer	N1-pyrazolospiroketone acetyl-coa carboxylase inhibitors
CA3017128C (en) *	2009-12-31	2021-08-31	Deka Products Limited Partnership	Infusion pump assembly
WO2011140425A1 (en)	2010-05-06	2011-11-10	Vertex Pharmaceuticals Incorporated	Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
US8933024B2 (en)	2010-06-18	2015-01-13	Sanofi	Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
CN101851237B (zh) *	2010-06-18	2012-10-17	南方医科大学	一种螺环化合物及其制备方法和应用
RS55224B1 (sr)	2010-09-30	2017-02-28	Pfizer	N1-pirazolospiroketon acetil-coa karboksilaza inhibitori
BR112013010310A2 (pt)	2010-10-29	2016-11-29	Pfizer	inibidores de acetil-coa carboxilase de lactama n1/n2
WO2012077655A1 (ja) *	2010-12-07	2012-06-14	塩野義製薬株式会社	Ｇｐｒ１１９アゴニスト活性を有するスピロ誘導体
RU2634900C2 (ru)	2011-02-02	2017-11-08	Вертекс Фармасьютикалз Инкорпорейтед	Спироциклические пирролопиразин(пиперидин)амиды в качестве модуляторов ионных каналов
AU2012217616B2 (en)	2011-02-18	2017-03-02	Vertex Pharmaceuticals Incorporated	Chroman - spirocyclic piperidine amides as modulators of ion channels
EP2686325B1 (en)	2011-03-14	2016-12-14	Vertex Pharmaceuticals Incorporated	Morpholine-spirocyclic piperidine amides as modulators of ion channels
PE20141187A1 (es)	2011-04-22	2014-09-18	Pfizer	Inhibidores sustituidos de aeitl-coa carboxilasa
TW201300393A (zh) *	2011-05-20	2013-01-01	Kowa Co	新穎之螺哌啶衍生物及含有其之醫藥
WO2013113776A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
WO2013113788A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
WO2013113716A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
WO2013113720A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
WO2013113773A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
WO2013113715A1 (en)	2012-02-03	2013-08-08	Basf Se	Fungicidal pyrimidine compounds
AU2013214137A1 (en)	2012-02-03	2014-08-21	Basf Se	Fungicidal pyrimidine compounds
US8889730B2 (en)	2012-04-10	2014-11-18	Pfizer Inc.	Indole and indazole compounds that activate AMPK
US9394285B2 (en)	2013-03-15	2016-07-19	Pfizer Inc.	Indole and indazole compounds that activate AMPK
KR20160006762A (ko)	2013-05-10	2016-01-19	님버스 아폴로, 인코포레이티드	Acc 억제제 및 이의 용도
US10208044B2 (en)	2013-05-10	2019-02-19	Gilead Apollo, Llc	ACC inhibitors and uses thereof
SG11201600711PA (en)	2013-09-12	2016-03-30	Pfizer	Use of acetyl-coa carboxylase inhibitors for treating acne vulgaris
WO2018112204A1 (en)	2016-12-14	2018-06-21	Cephalon, Inc.	Spiropiperidine derivatives
WO2019006324A1 (en) *	2017-06-30	2019-01-03	Quixgen, Inc.	NEW SPIROLACTONE COMPOUNDS

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JP2005162612A (ja)	2002-01-09	2005-06-23	Ajinomoto Co Inc	アシルスルホンアミド誘導体
JP2005170790A (ja)	2002-01-09	2005-06-30	Ajinomoto Co Inc	Ｎ−アルキルスルフォニル置換アミド誘導体
NZ534582A (en)	2002-02-27	2006-03-31	Pfizer Prod Inc	ACC inhibitors
JP2005320250A (ja)	2002-05-09	2005-11-17	Ajinomoto Co Inc	ビスラクトン誘導体及びその医薬組成物としての使用
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WO2004092179A1 (ja)	2003-04-14	2004-10-28	Nippon Soda Co. Ltd.	スピロ誘導体、製造法および抗酸化薬
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JP2005119987A (ja) *	2003-10-15	2005-05-12	Ajinomoto Co Inc	アシルスルホンアミド誘導体
EP1802623A1 (en)	2004-10-12	2007-07-04	Novo Nordisk A/S	11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds
US20060122210A1 (en)	2004-11-18	2006-06-08	Wenqing Yao	Inhibitors of 11-beta hydroxyl steroid dehydrogenase type I and methods of using the same
CA2605985A1 (en)	2005-05-03	2006-11-09	Pfizer Inc.	Amide resorcinol compounds
NZ564591A (en) *	2005-07-19	2010-01-29	Merck & Co Inc	Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
WO2008065508A1 (en)	2006-11-29	2008-06-05	Pfizer Products Inc.	Spiroketone acetyl-coa carboxylase inhibitors
JP5271917B2 (ja) *	2007-01-12	2013-08-21	メルク・シャープ・アンド・ドーム・コーポレーション	スピロクロマノン誘導体

2008
- 2008-01-04 PE PE2008000089A patent/PE20081559A1/es not_active Application Discontinuation
- 2008-01-07 TW TW097100608A patent/TW200836727A/zh unknown
- 2008-01-08 WO PCT/US2008/000221 patent/WO2008088688A1/en active Application Filing
- 2008-01-08 JP JP2009545577A patent/JP5319550B2/ja not_active Expired - Fee Related
- 2008-01-08 RU RU2009130736/04A patent/RU2009130736A/ru not_active Application Discontinuation
- 2008-01-08 CN CN2008800021443A patent/CN101631791B/zh not_active Expired - Fee Related
- 2008-01-08 MX MX2009007502A patent/MX2009007502A/es unknown
- 2008-01-08 US US12/007,000 patent/US8093389B2/en active Active
- 2008-01-08 UA UAA200908468A patent/UA103990C2/ru unknown
- 2008-01-08 NZ NZ577825A patent/NZ577825A/en not_active IP Right Cessation
- 2008-01-08 WO PCT/US2008/000223 patent/WO2008088689A1/en active Application Filing
- 2008-01-08 CA CA2674573A patent/CA2674573C/en not_active Expired - Fee Related
- 2008-01-08 BR BRPI0806531-4A2A patent/BRPI0806531A2/pt not_active IP Right Cessation
- 2008-01-08 AU AU2008205638A patent/AU2008205638B2/en not_active Ceased
- 2008-01-08 EP EP08713050A patent/EP2111406B1/en active Active
- 2008-01-08 KR KR1020097014377A patent/KR20090108022A/ko not_active Application Discontinuation
- 2008-01-08 SG SG2012002739A patent/SG177977A1/en unknown
- 2008-01-09 AR ARP080100081A patent/AR064824A1/es not_active Application Discontinuation
- 2008-01-10 CL CL200800067A patent/CL2008000067A1/es unknown
2009
- 2009-06-12 ZA ZA200904138A patent/ZA200904138B/xx unknown
- 2009-07-06 GT GT200900194A patent/GT200900194A/es unknown
- 2009-07-06 HN HN2009001276A patent/HN2009001276A/es unknown
- 2009-07-08 NI NI200900139A patent/NI200900139A/es unknown
- 2009-07-09 DO DO2009000176A patent/DOP2009000176A/es unknown
- 2009-07-09 EC EC2009009503A patent/ECSP099503A/es unknown
- 2009-07-13 CO CO09072490A patent/CO6190611A2/es active IP Right Grant
- 2009-07-20 CR CR10944A patent/CR10944A/es unknown
- 2009-07-23 MA MA32114A patent/MA31108B1/fr unknown
- 2009-11-13 HK HK09110661.8A patent/HK1131136A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
HK1131136A1 (en)	2010-01-15
MX2009007502A (es)	2009-07-17
SG177977A1 (en)	2012-02-28
JP2010515733A (ja)	2010-05-13
KR20090108022A (ko)	2009-10-14
NI200900139A (es)	2010-02-24
EP2111406B1 (en)	2012-10-24
RU2009130736A (ru)	2011-02-20
GT200900194A (es)	2015-03-09
US20080171761A1 (en)	2008-07-17
CA2674573C (en)	2015-04-14
WO2008088688A1 (en)	2008-07-24
AR064824A1 (es)	2009-04-29
CL2008000067A1 (es)	2008-05-16
CR10944A (es)	2009-08-12
MA31108B1 (fr)	2010-01-04
CN101631791B (zh)	2012-12-12
ZA200904138B (en)	2010-04-28
CN101631791A (zh)	2010-01-20
EP2111406A1 (en)	2009-10-28
HN2009001276A (es)	2012-01-17
WO2008088689A1 (en)	2008-07-24
CA2674573A1 (en)	2008-07-24
CO6190611A2 (es)	2010-08-19
UA103990C2 (en)	2013-12-25
NZ577825A (en)	2012-04-27
JP5319550B2 (ja)	2013-10-16
ECSP099503A (es)	2009-08-28
TW200836727A (en)	2008-09-16
DOP2009000176A (es)	2009-08-31
US8093389B2 (en)	2012-01-10
PE20081559A1 (es)	2008-11-20
AU2008205638B2 (en)	2012-08-16
AU2008205638A1 (en)	2008-07-24

Legal Events

Date	Code	Title	Description
2014-06-10	B25D	Requested change of name of applicant approved	Owner name: BANYU PHARMACEUTICAL CO., LTD. (JP) , MERCK SHARP
2017-10-24	B07D	Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
2017-11-21	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
2018-03-13	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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