BRPI0617412B8 - anticorpo antiglipicano-3, agente anticâncer compreendendo o mesmo, bem como seu uso e seu processo de produção - Google Patents
anticorpo antiglipicano-3, agente anticâncer compreendendo o mesmo, bem como seu uso e seu processo de produçãoInfo
- Publication number
- BRPI0617412B8 BRPI0617412B8 BRPI0617412A BRPI0617412A BRPI0617412B8 BR PI0617412 B8 BRPI0617412 B8 BR PI0617412B8 BR PI0617412 A BRPI0617412 A BR PI0617412A BR PI0617412 A BRPI0617412 A BR PI0617412A BR PI0617412 B8 BRPI0617412 B8 BR PI0617412B8
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- antiglypican
- well
- production process
- amino acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/303—Liver or Pancreas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/524—CH2 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
- C07K2317/526—CH3 domain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/72—Increased effector function due to an Fc-modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/251,561 US20070087005A1 (en) | 2005-10-14 | 2005-10-14 | Anti-glypican-3 antibody |
US11/251,561 | 2005-10-14 | ||
PCT/US2006/039682 WO2007047291A2 (en) | 2005-10-14 | 2006-10-11 | Anti-glypican-3 antibody |
Publications (3)
Publication Number | Publication Date |
---|---|
BRPI0617412A2 BRPI0617412A2 (pt) | 2011-07-26 |
BRPI0617412B1 BRPI0617412B1 (pt) | 2020-11-17 |
BRPI0617412B8 true BRPI0617412B8 (pt) | 2022-08-30 |
Family
ID=37890328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0617412A BRPI0617412B8 (pt) | 2005-10-14 | 2006-10-11 | anticorpo antiglipicano-3, agente anticâncer compreendendo o mesmo, bem como seu uso e seu processo de produção |
Country Status (12)
Country | Link |
---|---|
US (3) | US20070087005A1 (pt) |
EP (1) | EP1933872B1 (pt) |
JP (1) | JP5303274B2 (pt) |
KR (1) | KR101397858B1 (pt) |
CN (2) | CN101287492B (pt) |
AU (1) | AU2006304100C1 (pt) |
BR (1) | BRPI0617412B8 (pt) |
CA (1) | CA2624894C (pt) |
ES (1) | ES2470374T3 (pt) |
HK (2) | HK1120427A1 (pt) |
IL (1) | IL190472A (pt) |
WO (1) | WO2007047291A2 (pt) |
Families Citing this family (70)
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WO2004022597A1 (ja) * | 2002-09-04 | 2004-03-18 | Chugai Seiyaku Kabushiki Kaisha | Gpc3の血中可溶化n端ペプチドに対する抗体 |
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US20090010920A1 (en) * | 2003-03-03 | 2009-01-08 | Xencor, Inc. | Fc Variants Having Decreased Affinity for FcyRIIb |
US9051373B2 (en) | 2003-05-02 | 2015-06-09 | Xencor, Inc. | Optimized Fc variants |
US9714282B2 (en) | 2003-09-26 | 2017-07-25 | Xencor, Inc. | Optimized Fc variants and methods for their generation |
US8101720B2 (en) * | 2004-10-21 | 2012-01-24 | Xencor, Inc. | Immunoglobulin insertions, deletions and substitutions |
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UA93488C2 (uk) * | 2004-10-26 | 2011-02-25 | Чугаі Сейяку Кабусікі Кайся | Композиція анти-гліпікан 3-антитіл, що мають модифікований цукровий ланцюг |
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EP2325206B1 (en) | 2004-11-12 | 2014-03-19 | Xencor, Inc. | Fc variants with altered binding to fcrn |
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2005
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- 2006-10-11 CA CA2624894A patent/CA2624894C/en not_active Expired - Fee Related
- 2006-10-11 ES ES06825738.5T patent/ES2470374T3/es active Active
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- 2006-10-11 WO PCT/US2006/039682 patent/WO2007047291A2/en active Application Filing
- 2006-10-11 CN CN201210178007.3A patent/CN102850455B/zh not_active Expired - Fee Related
- 2006-10-11 KR KR1020087009364A patent/KR101397858B1/ko active IP Right Grant
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JP2009511587A (ja) | 2009-03-19 |
WO2007047291A3 (en) | 2007-06-21 |
CA2624894C (en) | 2016-11-08 |
US20150098941A1 (en) | 2015-04-09 |
US10118959B2 (en) | 2018-11-06 |
HK1120427A1 (en) | 2009-04-03 |
CN102850455A (zh) | 2013-01-02 |
CA2624894A1 (en) | 2007-04-26 |
EP1933872B1 (en) | 2014-03-19 |
BRPI0617412B1 (pt) | 2020-11-17 |
CN101287492A (zh) | 2008-10-15 |
IL190472A (en) | 2017-01-31 |
US9102739B2 (en) | 2015-08-11 |
CN101287492B (zh) | 2013-06-12 |
AU2006304100B2 (en) | 2013-03-07 |
US20070087005A1 (en) | 2007-04-19 |
HK1176076A1 (en) | 2013-07-19 |
IL190472A0 (en) | 2008-11-03 |
JP5303274B2 (ja) | 2013-10-02 |
EP1933872A2 (en) | 2008-06-25 |
AU2006304100A1 (en) | 2007-04-26 |
KR101397858B1 (ko) | 2014-05-20 |
CN102850455B (zh) | 2015-02-18 |
ES2470374T3 (es) | 2014-06-23 |
KR20080068023A (ko) | 2008-07-22 |
US20080267979A1 (en) | 2008-10-30 |
AU2006304100C1 (en) | 2013-08-29 |
BRPI0617412A2 (pt) | 2011-07-26 |
WO2007047291A2 (en) | 2007-04-26 |
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