BRPI0512607A - dispositivo para a transferência de moléculas para células que utiliza uma força elétrica - Google Patents

dispositivo para a transferência de moléculas para células que utiliza uma força elétrica

Info

Publication number
BRPI0512607A
BRPI0512607A BRPI0512607-0A BRPI0512607A BRPI0512607A BR PI0512607 A BRPI0512607 A BR PI0512607A BR PI0512607 A BRPI0512607 A BR PI0512607A BR PI0512607 A BRPI0512607 A BR PI0512607A
Authority
BR
Brazil
Prior art keywords
cells
electric force
electric current
transferring molecules
molecules
Prior art date
Application number
BRPI0512607-0A
Other languages
English (en)
Inventor
Yves Scherman
Original Assignee
Sphergen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0406943A external-priority patent/FR2872055B1/fr
Priority claimed from FR0410172A external-priority patent/FR2872056B1/fr
Priority claimed from FR0500603A external-priority patent/FR2880808A1/fr
Application filed by Sphergen filed Critical Sphergen
Publication of BRPI0512607A publication Critical patent/BRPI0512607A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Electrotherapy Devices (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

DISPOSITIVO PARA A TRANSFERêNCIA DE MOLéCULAS PARA CéLULAS QUE UTILIZA UMA FORçA ELéTRICA. A invenção refere-se a um dispositivo e um método para uma aplicação ótima de um princípio ativo (36) em um tecido humano ou animal para quimioterapia ou terapia de genes, utilizando um campo ou corrente elétrica. O dispositivo consiste em eletrodos conectados em um gerador de corrente elétrica, que provê uma melhor eficiência, reprodutibilidade e segurança as quais são conseguidas através da utilização de dispositivos de eletrodo adaptados e a utilização de uma intensidade de corrente ótima.
BRPI0512607-0A 2004-06-24 2005-06-24 dispositivo para a transferência de moléculas para células que utiliza uma força elétrica BRPI0512607A (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
FR0406943A FR2872055B1 (fr) 2004-06-24 2004-06-24 Dispositif pour le transfert de molecules aux cellules utilisant une force d'origine physique et combinaison permettant la mise en oeuvre du procede
FR0410172A FR2872056B1 (fr) 2004-06-24 2004-09-27 Dispositif pour l'administration de principe actif aux cellules et tissus utilisant une ou deux forces physiques
FR0500603A FR2880808A1 (fr) 2005-01-20 2005-01-20 Dispositif pour l'administration de principe actif aux cellules et tissus a l'aide d'electrodes de surface non invasives
FR0502215 2005-03-04
PCT/FR2005/001611 WO2006010837A2 (fr) 2004-06-24 2005-06-24 Dispositif our le transfert de molecules aux cellules utilisant une force electrique

Publications (1)

Publication Number Publication Date
BRPI0512607A true BRPI0512607A (pt) 2008-03-25

Family

ID=35517221

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512607-0A BRPI0512607A (pt) 2004-06-24 2005-06-24 dispositivo para a transferência de moléculas para células que utiliza uma força elétrica

Country Status (6)

Country Link
US (1) US20070156082A1 (pt)
EP (1) EP1786514B1 (pt)
JP (3) JP5197006B2 (pt)
BR (1) BRPI0512607A (pt)
CA (1) CA2572122A1 (pt)
WO (1) WO2006010837A2 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2893256B1 (fr) * 2005-11-14 2008-08-15 Yves Scherman Generateur d'impulsions electriques unipolaires.
EP2594315A1 (en) 2007-07-10 2013-05-22 Sapiens Steering Brain Stimulation B.V. Neurostimulation system
SG154343A1 (en) * 2008-01-08 2009-08-28 Ting Choon Meng Method and apparatus for intra-articular injection or aspiration
FR2928536B1 (fr) * 2008-03-14 2012-04-27 Inst Nat Sante Rech Med Dispositif d'injection dans l'oeil
AU2015201289B2 (en) * 2008-03-14 2016-12-01 Institut National De La Sante Et De La Recherche Medicale Eye injection device
WO2010061376A1 (en) * 2008-11-03 2010-06-03 Ben-Gurion University Of The Negev Research And Development Authority Method and apparatus for thrombus dissolution/thrombectomy by an electrode catheter device
WO2011034939A1 (en) * 2009-09-15 2011-03-24 Rush University Medical Center Energy-releasing carbon nanotube transponder and method of using same
IT1395992B1 (it) * 2009-10-27 2012-11-09 Caccia Testa per elettroporazione
AU2011223768B2 (en) 2010-03-01 2014-10-30 Inovio Pharmaceuticals, Inc. Multiple tissue layer electroporation applicator and device
ITTO20110411A1 (it) * 2011-05-11 2012-11-12 Consiglio Nazionale Ricerche Dispositivo per elettroporazione
CA2839196A1 (en) 2011-06-15 2012-12-20 Chrontech Pharma Ab Injection needle and device
US11311332B2 (en) 2011-08-23 2022-04-26 Magneto Thrombectomy Solutions Ltd. Thrombectomy devices
CN115737104A (zh) * 2015-03-31 2023-03-07 昂科赛克医疗公司 用于改进的基于组织感测的电穿孔的***和方法
EP3421078B1 (en) * 2016-02-22 2023-04-05 Tokyo Metropolitan Institute of Medical Science Electrodes for electroporation
CA3018223A1 (en) * 2016-03-28 2017-10-05 Ichor Medical Systems, Inc. Method and apparatus for delivery of therapeutic agents
US12029475B2 (en) 2017-03-22 2024-07-09 Magneto Thrombectomy Solutions Ltd. Thrombectomy using both electrostatic and suction forces
JP6884037B2 (ja) * 2017-05-29 2021-06-09 株式会社ジェイメック パルス電圧治療装置
KR101889048B1 (ko) * 2017-08-11 2018-08-16 문창수 전기적 자극을 가하는 약물주입용 기구 세트
WO2019102307A1 (en) 2017-11-23 2019-05-31 Magneto Thrombectomy Solutions Ltd. Tubular thrombectomy devices
US11071860B2 (en) 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US5318514A (en) 1992-08-17 1994-06-07 Btx, Inc. Applicator for the electroporation of drugs and genes into surface cells
JPH06327777A (ja) * 1993-03-26 1994-11-29 Gijutsu Kenkyu Kumiai Iryo Fukushi Kiki Kenkyusho 電気的薬剤導入装置
US5993434A (en) * 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
JPH07299143A (ja) * 1994-05-09 1995-11-14 Kenji Tsubota 医科用注射針
AUPM982694A0 (en) * 1994-12-02 1995-01-05 University Of Queensland, The Iontophoresis method and apparatus
WO1999004850A1 (en) * 1997-07-22 1999-02-04 Emed Corporation Needle for iontophoretic delivery of agent
JP2002512552A (ja) * 1997-07-22 2002-04-23 イーメッド コーポレイション 心臓組織中への薬剤のイオン電気導入法による配送
US6055453A (en) * 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US6241701B1 (en) * 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
AU770092B2 (en) * 1998-07-13 2004-02-12 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
US6542780B1 (en) * 1999-12-01 2003-04-01 Vertis Neuroscience, Inc. Method and apparatus for electrically coupling a percutaneous probe
WO2001089455A2 (en) * 2000-05-22 2001-11-29 Merck & Company, Inc. System and method for assessing the performance of a pharmaceutical agent delivery system
US20040092860A1 (en) * 2000-07-26 2004-05-13 Dev Nagendu B. Skin and muscle-targeted gene therapy by pulsed electrical field
JP2002282371A (ja) * 2001-03-28 2002-10-02 Polytronics Ltd 低電圧駆動型イオントフォレシス素子
US20020198567A1 (en) 2001-06-07 2002-12-26 Yona Keisari Electro-endocytotic therapy as a treatment modality of cancer
FR2830767B1 (fr) * 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese ou electroporation introculaire
US7245963B2 (en) * 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
EP1480692A2 (en) * 2002-03-07 2004-12-01 Merck & Co., Inc. Clinical syringe with electrical stimulation aspects
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
ATE402732T1 (de) * 2002-04-16 2008-08-15 Cyto Pulse Sciences Inc Verfahren zur behandlung von biologischen materialien mit übersetzenden elektrischen feldern und elektroden-polaritäts-umkehr
US20050070841A1 (en) 2002-07-04 2005-03-31 Inovio As Electroporation device and injection apparatus
AU2003276857A1 (en) * 2002-09-04 2004-03-29 William F. Urmey Positioning system for a nerve stimulator needle
EE05601B2 (et) 2010-12-31 2015-06-15 As Myoton Seade ja meetod pehme bioloogilise koe mehaanilise pingeseisundi, elastsuse, dünaamilise jäikuse, roomavuse ja mehaanilise pinge relaksatsiooniaega iseloomustavate parameetrite samaaegseks mõõtmiseks reaalajas ning arvutiprogrammi produkt

Also Published As

Publication number Publication date
CA2572122A1 (fr) 2006-02-02
WO2006010837A2 (fr) 2006-02-02
EP1786514A2 (fr) 2007-05-23
JP2015163230A (ja) 2015-09-10
JP2012250044A (ja) 2012-12-20
WO2006010837A3 (fr) 2006-04-06
JP2008503292A (ja) 2008-02-07
EP1786514B1 (fr) 2015-01-07
US20070156082A1 (en) 2007-07-05
JP5197006B2 (ja) 2013-05-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A ANUIDADE.

B08G Application fees: restoration [chapter 8.7 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]