BRPI0509135A - composição farmacêutica de liberação controlada e método para produzir a mesma - Google Patents

composição farmacêutica de liberação controlada e método para produzir a mesma

Info

Publication number
BRPI0509135A
BRPI0509135A BRPI0509135-7A BRPI0509135A BRPI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A BR PI0509135 A BRPI0509135 A BR PI0509135A
Authority
BR
Brazil
Prior art keywords
pharmaceutical composition
controlled release
release pharmaceutical
producing
same
Prior art date
Application number
BRPI0509135-7A
Other languages
English (en)
Inventor
Takashi Yoshitake
Mitsuru Mizuno
Kenji Moroshima
Shigeru Aoki
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of BRPI0509135A publication Critical patent/BRPI0509135A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

COMPOSIçãO FARMACêTICA DE LIBERAçãO CONTROLADA E MéTODO PARA PRODUZIRA MESMA. é um objeto da presente invenção, no caso uma composição farmacêutica de liberação controlada, particularmente uma composição farmacêutica de liberação por pulso, contendo uma substância ativa fisiologicamente instável em ácido, para prover uma composição farmacêutica que tem pequena variação em tempo de latência de dissolução e alta confiabilidade de características de dissolução. A presente invenção descreve uma composição farmacêutica de liberação controlada compreendendo: a) um núcleo que contém uma substância ativa fisiologicamente instável em ácido e um desintegrante; b) um revestimento de controle de liberação que reveste o núcleo, e que contém um polímero insolúvel em água, um polímero entérico e uma cera hidrofóbica.
BRPI0509135-7A 2004-03-26 2005-03-23 composição farmacêutica de liberação controlada e método para produzir a mesma BRPI0509135A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004093506 2004-03-26
PCT/JP2005/005217 WO2005092336A1 (ja) 2004-03-26 2005-03-23 溶出制御製剤とその製造方法

Publications (1)

Publication Number Publication Date
BRPI0509135A true BRPI0509135A (pt) 2007-08-28

Family

ID=35055974

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509135-7A BRPI0509135A (pt) 2004-03-26 2005-03-23 composição farmacêutica de liberação controlada e método para produzir a mesma

Country Status (17)

Country Link
US (2) US20080095839A1 (pt)
EP (1) EP1728512A1 (pt)
JP (1) JPWO2005092336A1 (pt)
KR (1) KR100794078B1 (pt)
CN (1) CN1938026A (pt)
AU (1) AU2005225283B2 (pt)
BR (1) BRPI0509135A (pt)
CA (1) CA2557791C (pt)
IL (1) IL177087A (pt)
MX (1) MXPA06010785A (pt)
MY (1) MY139427A (pt)
NO (1) NO20064874L (pt)
NZ (1) NZ549838A (pt)
RU (1) RU2337687C2 (pt)
TW (1) TW200602085A (pt)
WO (1) WO2005092336A1 (pt)
ZA (1) ZA200607603B (pt)

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RU2401125C2 (ru) 2004-12-27 2010-10-10 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Способ стабилизации лекарственного средства против деменции
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JP2014122328A (ja) * 2012-11-22 2014-07-03 Shin Etsu Chem Co Ltd 押出成形機又は射出成形機洗浄用組成物及び押出成形機又は射出成形機の洗浄方法
US20140275038A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
CN103976972B (zh) * 2014-05-26 2017-09-12 中国药科大学 酒石酸唑吡坦口服脉冲控释给药***及其制备方法
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
US20190008787A1 (en) 2015-07-17 2019-01-10 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
EP3117824A1 (en) 2015-07-17 2017-01-18 BE Pharbel Manufacturing Multilayered pharmaceutically active compound-releasing microparticles in a liquid dosage form
CN105796532B (zh) * 2016-03-28 2018-12-21 中国医药集团总公司四川抗菌素工业研究所 一种雷贝拉唑钠缓释胶囊及其制备方法
MX2021005691A (es) * 2018-11-19 2021-07-07 Jazz Pharmaceuticals Ireland Ltd Formulaciones de farmacos resistentes al alcohol.
KR20210071242A (ko) * 2019-12-06 2021-06-16 진양제약주식회사 제약 조성물
CN113069428B (zh) * 2021-04-02 2023-02-10 珠海润都制药股份有限公司 一种雷贝拉唑钠肠溶片的制备方法
KR102647279B1 (ko) 2021-04-08 2024-03-18 대한뉴팜(주) 라베프라졸의 우수한 방출 특성을 갖는 라베프라졸 나트륨 및 산화마그네슘을 포함하는 제제 및 이의 제조방법

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Also Published As

Publication number Publication date
KR20060134124A (ko) 2006-12-27
IL177087A0 (en) 2006-12-10
JPWO2005092336A1 (ja) 2008-02-07
KR100794078B1 (ko) 2008-01-10
NZ549838A (en) 2010-04-30
AU2005225283B2 (en) 2008-09-18
IL177087A (en) 2011-11-30
CA2557791C (en) 2011-03-08
US20070110806A1 (en) 2007-05-17
NO20064874L (no) 2006-12-19
US20120003311A9 (en) 2012-01-05
CA2557791A1 (en) 2005-10-06
RU2006134052A (ru) 2008-04-10
RU2337687C2 (ru) 2008-11-10
AU2005225283A1 (en) 2005-10-06
EP1728512A1 (en) 2006-12-06
WO2005092336A1 (ja) 2005-10-06
MY139427A (en) 2009-09-30
CN1938026A (zh) 2007-03-28
ZA200607603B (en) 2007-05-30
TW200602085A (en) 2006-01-16
MXPA06010785A (es) 2007-03-28
US20080095839A1 (en) 2008-04-24

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2204 DE 02/04/2013.