BRPI0507386A - combinação de reagentes e método para medição direta em tira de teste do colesterol e lipoproteìnas de baixa densidade à temperatura ambiente - Google Patents

combinação de reagentes e método para medição direta em tira de teste do colesterol e lipoproteìnas de baixa densidade à temperatura ambiente

Info

Publication number
BRPI0507386A
BRPI0507386A BRPI0507386-3A BRPI0507386A BRPI0507386A BR PI0507386 A BRPI0507386 A BR PI0507386A BR PI0507386 A BRPI0507386 A BR PI0507386A BR PI0507386 A BRPI0507386 A BR PI0507386A
Authority
BR
Brazil
Prior art keywords
low density
room temperature
direct measurement
cholesterol
density lipoproteins
Prior art date
Application number
BRPI0507386-3A
Other languages
English (en)
Inventor
Gregory M Lawrence
John Pasqua
Original Assignee
Polymer Technology Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polymer Technology Systems Inc filed Critical Polymer Technology Systems Inc
Publication of BRPI0507386A publication Critical patent/BRPI0507386A/pt
Publication of BRPI0507386B1 publication Critical patent/BRPI0507386B1/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/525—Multi-layer analytical elements
    • G01N33/526—Multi-layer analytical elements the element being adapted for a specific analyte
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/044—Hyperlipemia or hypolipemia, e.g. dyslipidaemia, obesity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

COMBINAçãO DE REAGENTES E MéTODO PARA MEDIçãO DIRETA EM TIRA DE TESTE DO COLESTEROL DE LIPOPROTEìNAS DE BAIXA DENSIDADE à TEMPERATURA AMBIENTE. A presente invenção refere-se ao colesterol de Lipoproteínas de Baixa Densidade (LDL-C), que é medido diretamente com uma tira de teste à temperatura ambiente usando-se um reagente que se vale da densidade de carga superficial variável em LDLs e não-LDLs para seletivamente tornar LDLC disponível para teste.
BRPI0507386A 2004-02-03 2005-02-03 "tira de teste de fluxo vertical para uso na detecção direta de colesterol produzido por lipoproteinas de baixa densidade em uma amostra de sangue total, plasma ou soro" BRPI0507386B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54168104P 2004-02-03 2004-02-03
US10/962,272 US7435577B2 (en) 2004-02-03 2004-10-11 Direct measurement of chlolesterol from low density lipoprotein with test strip
PCT/US2005/003234 WO2005074609A2 (en) 2004-02-03 2005-02-03 Test strip composition and method to measure cholesterol from low density lipoproteins

Publications (2)

Publication Number Publication Date
BRPI0507386A true BRPI0507386A (pt) 2007-07-10
BRPI0507386B1 BRPI0507386B1 (pt) 2017-01-24

Family

ID=34811458

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0507386A BRPI0507386B1 (pt) 2004-02-03 2005-02-03 "tira de teste de fluxo vertical para uso na detecção direta de colesterol produzido por lipoproteinas de baixa densidade em uma amostra de sangue total, plasma ou soro"

Country Status (12)

Country Link
US (1) US7435577B2 (pt)
EP (1) EP1725650B1 (pt)
JP (1) JP4785753B2 (pt)
CN (1) CN104931712A (pt)
AU (1) AU2005209856B2 (pt)
BR (1) BRPI0507386B1 (pt)
CA (1) CA2554776C (pt)
EA (1) EA010414B1 (pt)
IL (1) IL177226A (pt)
PL (1) PL1725650T3 (pt)
WO (1) WO2005074609A2 (pt)
ZA (1) ZA200606561B (pt)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7435577B2 (en) 2004-02-03 2008-10-14 Polymer Technology Systems, Inc. Direct measurement of chlolesterol from low density lipoprotein with test strip
US8465696B2 (en) * 2004-02-03 2013-06-18 Polymer Technology Systems, Inc. Dry test strip with controlled flow and method of manufacturing same
US20060062688A1 (en) * 2004-02-03 2006-03-23 Polymer Technology Systems, Inc. Bodily fluid analysis system
US7625721B2 (en) 2004-02-03 2009-12-01 Polymer Technology Systems, Inc. Non-precipitating bodily fluid analysis system
US7491542B2 (en) * 2004-07-12 2009-02-17 Kim Scheuringer Test device for determining the concentration of LDL-cholesterol in a sample
WO2006023679A1 (en) * 2004-08-17 2006-03-02 Polymer Technology Systems, Inc. Apparatus and method for manufacturing bodily fluid test strip
EP1779119B1 (en) * 2004-08-17 2012-08-01 Polymer Technology Systems, Inc. Non-precipitating bodily fluid analysis method
JP5247158B2 (ja) 2008-01-16 2013-07-24 パナソニック株式会社 試料溶液分析方法および試料溶液分析装置
WO2009155339A1 (en) * 2008-06-17 2009-12-23 Polymer Technology Systems, Inc. System and method for packaging dry test strips
KR101671040B1 (ko) * 2008-11-14 2016-10-31 교와 메덱스 가부시키가이샤 저밀도 리포 단백 중의 콜레스테롤의 측정 방법, 측정용 시약 및 측정용 키트
KR101058743B1 (ko) * 2009-06-04 2011-08-24 주식회사 인포피아 콜레스테롤 측정 스트립 및 이를 이용한 콜레스테롤 검출 방법
KR101110561B1 (ko) * 2009-06-04 2012-02-15 주식회사 인포피아 바이오 센서
KR101203385B1 (ko) * 2009-06-04 2012-11-21 주식회사 인포피아 혈액의 퍼짐성이 향상된 측정 스트립
JP5460183B2 (ja) * 2009-08-28 2014-04-02 パナソニック株式会社 分析用試薬および分析用デバイス
EP2455760B1 (en) * 2009-07-15 2016-04-13 Panasonic Healthcare Holdings Co., Ltd. Analysis reagent and analysis device having the analysis reagent carried therein
US8012770B2 (en) 2009-07-31 2011-09-06 Invisible Sentinel, Inc. Device for detection of antigens and uses thereof
MX2012004105A (es) 2009-10-09 2012-09-07 Invisible Sentinel Inc Dispositivo para deteccion de antigenos y usos del mismo.
JP5285000B2 (ja) * 2010-02-23 2013-09-11 富士フイルム株式会社 低密度リポ蛋白コレステロールの測定方法
JP5832995B2 (ja) * 2010-04-30 2015-12-16 協和メデックス株式会社 低密度リポ蛋白中のコレステロールの測定方法、測定用試薬及び測定用キット
EP2668501B1 (en) 2011-01-27 2019-06-12 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
GB2503601A (en) * 2011-04-22 2014-01-01 Polymer Technology Systems Inc Blood Separation system and method for a dry test strip
CN104919055B (zh) 2012-03-09 2018-06-19 因威瑟堡善迪诺有限公司 用单一信号检测多种分析物的方法和组合物
CA2872525A1 (en) 2012-05-04 2013-11-07 Polymer Technology Systems, Inc. Systems and methods for non-fasting ldl cholesterol assays
SG11201607582RA (en) * 2014-03-07 2016-10-28 Univ California Devices for integrating analyte extraction, concentration and detection
JP6917889B2 (ja) * 2014-07-03 2021-08-11 アビオニック・ソシエテ・アノニム 全血などの流体サンプルの迅速分子定量化のためのカプセル
MA41883B1 (fr) * 2015-07-23 2019-03-29 Gentian Diagnostics As Procédé pour évaluer les récepteurs de surface cellulaire des cellules sanguines
CA3002020C (en) 2015-09-04 2024-02-27 The Regents Of The University Of California Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications
CN116083539A (zh) 2016-06-09 2023-05-09 加利福尼亚大学董事会 纯化和扩增核酸的方法
WO2018039139A1 (en) 2016-08-22 2018-03-01 The Regents Of The University Of California Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
WO2018138139A1 (en) * 2017-01-24 2018-08-02 Gentian As Method for assessing cell surface receptors of blood cells
US11209427B2 (en) 2017-03-27 2021-12-28 The Regents Of The University Of California Semi-quantitative lateral-flow immunoassay for the detection of CSF leaks
US11338294B2 (en) 2017-04-27 2022-05-24 Polybiomics, Inc. Orthogonal polybiosensing and imaging systems
US20200392558A1 (en) * 2017-09-01 2020-12-17 Hitachi Chemical Diagnostics Systems Co., Ltd. Method for measuring cholesterol in low-density lipoprotein, measurement reagent, and measurement kit
CN107402209B (zh) * 2017-09-15 2020-04-07 光景生物科技(苏州)有限公司 一种用于检测血清中低密度脂蛋白胆固醇的试纸条及其制备方法
JP6454950B1 (ja) * 2018-03-29 2019-01-23 株式会社明日香特殊検査研究所 粥状動脈硬化による心筋梗塞や脳梗塞のリスクが高いと判定する易酸化性ＶＬＤＬ（ＶＬＤＬ ｓｕｓｃｅｐｔｉｂｉｌｉｔｙ ｔｏ ｏｘｉｄａｔｉｏｎ）および易酸化性ＬＤＬ（ＬＤＬ ｓｕｓｃｅｐｔｉｂｉｌｉｔｙ ｔｏ ｏｘｉｄａｔｉｏｎ）の簡便な測定方法および測定装置

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809617A (en) 1972-11-15 1974-05-07 American Cyanamid Co Device for detecting anticholinesterase materials
US4178153A (en) 1977-11-21 1979-12-11 Damon Corporation Method and apparatus for chemical spot test analysis
DE3029579C2 (de) 1980-08-05 1985-12-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zur Abtrennung von Plasma oder Serum aus Vollblut
DE3217925A1 (de) 1982-05-13 1983-11-17 B. Braun Melsungen Ag, 3508 Melsungen Verfahren zur selektiven extrakorporalen praezipitation von low-density lipoproteinen aus vollserum oder plasma fuer diagnostische zwecke
DE3401932A1 (de) 1984-01-20 1985-08-01 Collmann GmbH & Co, Spezialmaschinenbau KG, 2400 Lübeck Verfahren und vorrichtung zum darbieten von verstaerkungseinlagen fuer schleifscheiben
DE3530993A1 (de) 1985-08-30 1987-03-05 Miles Lab Teststreifen mit festlegbarer probenaufnahmekapazitaet
TW203120B (pt) 1985-10-04 1993-04-01 Abbott Lab
DE3782597T3 (de) 1986-09-18 2002-09-05 Pacific Biotech Inc Immunodiagnostische Vorrichtung.
DE3787078T2 (de) 1986-11-24 1993-12-09 Abbott Lab Proberichtwirkung für analytisches Festphasengerät.
US4774192A (en) 1987-01-28 1988-09-27 Technimed Corporation A dry reagent delivery system with membrane having porosity gradient
JPH0264455A (ja) 1988-08-31 1990-03-05 Konica Corp 体液検査素子及びその製造方法
US5135716A (en) 1989-07-12 1992-08-04 Kingston Diagnostics, L.P. Direct measurement of HDL cholesterol via dry chemistry strips
DE3929032C2 (de) 1989-09-01 1998-09-03 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von HDL-Cholesterin mittels eines Schnelldiagnostikums mit integriertem Fraktionierschritt
AU634814B2 (en) 1989-09-14 1993-03-04 Terumo Kabushiki Kaisha Method for determination of ion concentration, specific gravity, or osmotic pressure of solution and apparatus therefor
JPH04324347A (ja) 1991-04-24 1992-11-13 Terumo Corp 試験具
GR1001410B (el) * 1991-08-02 1993-11-30 Ortho Pharma Corp Επινόημα & μέ?οδος διεξαγωγής βιολογικών δοκιμασιών περιέχοντας σύστημα μοριακής διαλογής.
US5286626A (en) * 1991-12-13 1994-02-15 Actimed Laboratories, Inc. Process and apparatus for direct determination of low density lipoprotein
US5460974A (en) 1992-10-13 1995-10-24 Miles Inc. Method of assaying whole blood for HDL cholesterol
US5401466A (en) * 1993-06-01 1995-03-28 Miles Inc. Device for the direct measurement of low density lipoprotein cholesterol
US5597532A (en) * 1994-10-20 1997-01-28 Connolly; James Apparatus for determining substances contained in a body fluid
JP2799835B2 (ja) 1995-01-31 1998-09-21 第一化学薬品株式会社 コレステロールの定量方法
EP0764848A4 (en) * 1995-03-20 2001-04-11 Kyowa Medex Co Ltd METHOD FOR QUANTIFYING CHOLESTEROL IN LOW DENSITY OR VERY LOW DENSITY LIPOPROTEIN
JPH10160724A (ja) * 1996-12-03 1998-06-19 Kdk Corp 試験片
CA2246308C (en) * 1996-12-09 2008-11-18 Denka Seiken Co., Ltd. Method for quantifying cholesterol in high-density lipoprotein
AU735659B2 (en) * 1997-04-14 2001-07-12 Denka Seiken Co., Ltd. Method for quantifying cholesterol present in low density lipoprotein
DE29715019U1 (de) 1997-08-21 1997-10-16 LRE Technology Partner GmbH, 80807 München Teststreifen für ein Meßgerät zur optischen Bestimmung der Konzentration einer Substanz in einer Körperflüssigkeit
DE69920937T2 (de) * 1998-09-18 2006-02-23 Kyowa Medex Co. Ltd. Verfahren zur quantifizierung von cholesterol in lipoproteinen und quantifizierungsreagenzien
JP2003501630A (ja) 1999-05-28 2003-01-14 ザ ガバメント オブ ザ ユナイテッド ステイツ オブ アメリカ， リプリゼンテッド バイ ザ セクレタリー オブ ザ デパートメント オブ ヘルス アンド ヒューマン サービシーズ リポタンパク質画分を連続的に測定するための同時試験
DE19942928C2 (de) 1999-09-08 2001-10-31 Ernst Markart Teststreifen
JP2001124780A (ja) * 1999-10-28 2001-05-11 Showa Denko Kk リポ蛋白質コレステロールの測定方法
DE60018039T2 (de) * 1999-11-22 2005-09-29 Matsushita Electric Industrial Co., Ltd., Kadoma Sensor und verfahren zum messen von cholesterin
US20030013649A1 (en) 2000-01-31 2003-01-16 Rosen Craig A. Nucleic acids, proteins, and antibodies
US6844149B2 (en) 2001-06-29 2005-01-18 International Business Machines Corporation Method, system, and apparatus for measurement and recording of blood chemistry and other physiological measurements
CA2460073A1 (en) 2001-09-17 2003-03-27 F. Hoffmann-La Roche Ag Embossed test strip system
EP1459064B1 (en) 2001-12-28 2008-02-13 Polymer Technology Systems, Inc. Test strip for determining concentration of triglycerides
DE10204606C1 (de) 2002-01-18 2003-10-16 Cholestech Corp Vorrichtung und Verfahren für Lipoproteine hoher Dichte
DE60207196T2 (de) * 2002-04-09 2006-07-20 Cholestech Corp., Hayward Verfahren und Vorrichtung zur Quantifizierung von Lipoprotein-Cholesterol hoher Dichte
US6759190B2 (en) 2002-06-15 2004-07-06 Acon Laboratories, Inc. Test strip for detection of analyte and methods of use
US20040126830A1 (en) * 2002-09-16 2004-07-01 Bruce Shull Test strip and method for determining LDL cholesterol concentration from whole blood
US7435577B2 (en) 2004-02-03 2008-10-14 Polymer Technology Systems, Inc. Direct measurement of chlolesterol from low density lipoprotein with test strip

Also Published As

Publication number Publication date
WO2005074609A2 (en) 2005-08-18
EP1725650B1 (en) 2014-11-26
CN104931712A (zh) 2015-09-23
PL1725650T3 (pl) 2015-07-31
IL177226A (en) 2011-09-27
JP2007523325A (ja) 2007-08-16
IL177226A0 (en) 2006-12-10
WO2005074609A3 (en) 2006-01-19
EA200601415A1 (ru) 2006-12-29
AU2005209856B2 (en) 2010-06-10
EA010414B1 (ru) 2008-08-29
BRPI0507386B1 (pt) 2017-01-24
JP4785753B2 (ja) 2011-10-05
ZA200606561B (en) 2008-01-08
US20050170447A1 (en) 2005-08-04
AU2005209856A1 (en) 2005-08-18
EP1725650A2 (en) 2006-11-29
CA2554776C (en) 2012-12-04
EP1725650A4 (en) 2012-03-21
CA2554776A1 (en) 2005-08-18
US7435577B2 (en) 2008-10-14

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