BRPI0413820A - derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio - Google Patents
derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênioInfo
- Publication number
- BRPI0413820A BRPI0413820A BRPI0413820-1A BRPI0413820A BRPI0413820A BR PI0413820 A BRPI0413820 A BR PI0413820A BR PI0413820 A BRPI0413820 A BR PI0413820A BR PI0413820 A BRPI0413820 A BR PI0413820A
- Authority
- BR
- Brazil
- Prior art keywords
- androgen receptor
- cycloamino
- modulating compounds
- receptor modulating
- quinolinone derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
Abstract
"DERIVADOS DE 6-CICLOAMINO-2-QUINOLINONA COMO COMPOSTOS MODULADORES DE RECEPTOR DE ANDROGêNIO". A presente invenção é dirigida a compostos, composições farmacêuticas e a métodos para modular processos mediados por AR. São também fornecidos métodos de preparar esses compostos e composições farmacêuticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49712503P | 2003-08-22 | 2003-08-22 | |
PCT/US2004/027483 WO2005018573A2 (en) | 2003-08-22 | 2004-08-23 | 6-cycloamino-2-quinolinone derivatives as androgen receptor modulator compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0413820A true BRPI0413820A (pt) | 2006-10-24 |
Family
ID=34216080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0413820-1A BRPI0413820A (pt) | 2003-08-22 | 2004-08-23 | derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio |
Country Status (9)
Country | Link |
---|---|
US (1) | US7816372B2 (pt) |
EP (1) | EP1656142A4 (pt) |
JP (2) | JP4709759B2 (pt) |
CN (1) | CN1838956A (pt) |
AU (1) | AU2004266160A1 (pt) |
BR (1) | BRPI0413820A (pt) |
CA (1) | CA2536349A1 (pt) |
MX (1) | MXPA06001751A (pt) |
WO (1) | WO2005018573A2 (pt) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7026484B2 (en) | 2001-02-23 | 2006-04-11 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
US7214690B2 (en) | 2001-02-23 | 2007-05-08 | Ligand Pharmaceuticals Incorporated | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods |
BRPI0413820A (pt) * | 2003-08-22 | 2006-10-24 | Ligand Pharm Inc | derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio |
WO2005090282A1 (en) | 2004-03-12 | 2005-09-29 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
EP1891067B1 (en) * | 2005-06-17 | 2016-01-13 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
AU2006282767A1 (en) | 2005-08-26 | 2007-03-01 | The Regents Of The University Of California | Non-steroidal antiandrogens |
WO2007123682A2 (en) * | 2006-04-03 | 2007-11-01 | Medexis S.A. | Detection of membrane androgen receptor (mar) agents |
JP2009079037A (ja) * | 2007-09-06 | 2009-04-16 | Sumitomo Chemical Co Ltd | アミロイドβタンパク質の蓄積を抑制するための医薬組成物 |
CA2709677C (en) * | 2007-12-21 | 2017-03-14 | Lin Zhi | Selective androgen receptor modulators (sarms) and uses thereof |
WO2012047617A1 (en) * | 2010-09-28 | 2012-04-12 | Radius Health, Inc. | Selective androgen receptor modulators |
AU2013353723B2 (en) | 2012-12-03 | 2018-02-22 | Pfizer Inc. | Novel selective androgen receptor modulators |
US10441567B2 (en) * | 2014-01-17 | 2019-10-15 | Ligand Pharmaceuticals Incorporated | Methods and compositions for modulating hormone levels |
EP3143019B1 (en) * | 2014-05-15 | 2020-12-16 | Pfizer Inc | Crystalline form of 6-[(4r)-4-methyl-1,2-dioxido-1,2,6-thiadiazinan-2-yl]isoquinoline-1-carbonitrile |
KR20160147007A (ko) * | 2014-05-30 | 2016-12-21 | 화이자 인코포레이티드 | 선택적인 안드로겐 수용체 조절제로서의 카보니트릴 유도체 |
CA2992698A1 (en) | 2015-07-17 | 2017-01-26 | Toyama Chemical Co., Ltd. | Nitrogen-containing heterocyclic compound |
AU2017385292B2 (en) * | 2016-12-27 | 2020-05-14 | Fujifilm Corporation | Antitumor agent and bromodomain inhibitor |
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FR2329276A1 (fr) | 1975-10-29 | 1977-05-27 | Roussel Uclaf | Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant |
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BRPI0413820A (pt) * | 2003-08-22 | 2006-10-24 | Ligand Pharm Inc | derivados de 6-cicloamino-2-quinolinona como compostos moduladores de receptor de androgênio |
WO2005090282A1 (en) | 2004-03-12 | 2005-09-29 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
CA2709677C (en) | 2007-12-21 | 2017-03-14 | Lin Zhi | Selective androgen receptor modulators (sarms) and uses thereof |
-
2004
- 2004-08-23 BR BRPI0413820-1A patent/BRPI0413820A/pt not_active Application Discontinuation
- 2004-08-23 JP JP2006524121A patent/JP4709759B2/ja not_active Expired - Fee Related
- 2004-08-23 MX MXPA06001751A patent/MXPA06001751A/es not_active Application Discontinuation
- 2004-08-23 CA CA002536349A patent/CA2536349A1/en not_active Abandoned
- 2004-08-23 WO PCT/US2004/027483 patent/WO2005018573A2/en active Application Filing
- 2004-08-23 US US10/566,569 patent/US7816372B2/en not_active Expired - Fee Related
- 2004-08-23 AU AU2004266160A patent/AU2004266160A1/en not_active Abandoned
- 2004-08-23 EP EP04782052A patent/EP1656142A4/en not_active Withdrawn
- 2004-08-23 CN CNA2004800241252A patent/CN1838956A/zh active Pending
-
2010
- 2010-03-31 JP JP2010080000A patent/JP2010195799A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1656142A4 (en) | 2011-06-22 |
US7816372B2 (en) | 2010-10-19 |
JP4709759B2 (ja) | 2011-06-22 |
CA2536349A1 (en) | 2005-03-03 |
US20080227810A9 (en) | 2008-09-18 |
WO2005018573A3 (en) | 2005-05-06 |
JP2007503398A (ja) | 2007-02-22 |
AU2004266160A1 (en) | 2005-03-03 |
EP1656142A2 (en) | 2006-05-17 |
WO2005018573A2 (en) | 2005-03-03 |
JP2010195799A (ja) | 2010-09-09 |
US20070066650A1 (en) | 2007-03-22 |
CN1838956A (zh) | 2006-09-27 |
MXPA06001751A (es) | 2006-05-12 |
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Legal Events
Date | Code | Title | Description |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |