BRPI0011449B8 - composição de antígeno compreendendo tetramiristoil cardiolipina e 1-palmitoil-2-oleil-sn-glicero-3-fosfocolina e método para detectar anticorpos anti-lipoidais em uma amostra humana biológica in vitro - Google Patents
composição de antígeno compreendendo tetramiristoil cardiolipina e 1-palmitoil-2-oleil-sn-glicero-3-fosfocolina e método para detectar anticorpos anti-lipoidais em uma amostra humana biológica in vitroInfo
- Publication number
- BRPI0011449B8 BRPI0011449B8 BRPI0011449A BR0011449A BRPI0011449B8 BR PI0011449 B8 BRPI0011449 B8 BR PI0011449B8 BR PI0011449 A BRPI0011449 A BR PI0011449A BR 0011449 A BR0011449 A BR 0011449A BR PI0011449 B8 BRPI0011449 B8 BR PI0011449B8
- Authority
- BR
- Brazil
- Prior art keywords
- antigen composition
- phosphocholine
- glycero
- palmitoyl
- oleyl
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/571—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses for venereal disease, e.g. syphilis, gonorrhoea
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/04—Phospholipids, i.e. phosphoglycerides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
patente de invenção: "método para detectar sífilis usando antígenos sintéticos". a presente invenção se refere a uma composição de antígeno e a um método para detecção de anticorpos ao treponema pallidum e também à diagnose de sífilis. a composição de antígeno contém cardiolipina sintética e lecitina sintética. a composição de antígeno pode adicionalmente conter colesterol e um álcool. a composição de antígeno é de utilidade como um imunoreagente em imunoensaios para a detecção de anticorpos associados à infecção causada por t. pallidum. os métodos são sensíveis e específicos para infecção causada pela t. pallidum.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13819299P | 1999-06-09 | 1999-06-09 | |
PCT/US2000/015828 WO2000075666A1 (en) | 1999-06-09 | 2000-06-08 | Method for detecting syphilis using synthetic antigens |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0011449A BR0011449A (pt) | 2002-03-19 |
BR0011449B1 BR0011449B1 (pt) | 2013-12-03 |
BRPI0011449B8 true BRPI0011449B8 (pt) | 2021-05-25 |
Family
ID=22480887
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0011449A BRPI0011449B8 (pt) | 1999-06-09 | 2000-06-08 | composição de antígeno compreendendo tetramiristoil cardiolipina e 1-palmitoil-2-oleil-sn-glicero-3-fosfocolina e método para detectar anticorpos anti-lipoidais em uma amostra humana biológica in vitro |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1185872B1 (pt) |
JP (1) | JP4531314B2 (pt) |
CN (1) | CN1195986C (pt) |
AT (1) | ATE316245T1 (pt) |
AU (1) | AU771548B2 (pt) |
BR (1) | BRPI0011449B8 (pt) |
CA (1) | CA2375448C (pt) |
DE (1) | DE60025605T2 (pt) |
RU (1) | RU2244933C2 (pt) |
WO (1) | WO2000075666A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10250368A1 (de) * | 2002-10-29 | 2004-05-19 | Viramed Biotech Ag | Mittel und Verfahren zur Diagnose einer Treponemainfektion |
US8148057B2 (en) | 2005-06-21 | 2012-04-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Methods, immunoassays and devices for detection of anti-lipoidal antibodies |
CN101243321A (zh) | 2005-06-21 | 2008-08-13 | 美国政府健康及人类服务部,疾病控制和预防中心 | 用于检测抗-类脂抗体的方法、免疫测定法和装置 |
US8778619B2 (en) | 2005-11-18 | 2014-07-15 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Oxidized cardiolipin and uses to detect cardiolipin antibodies |
BRPI0618713B8 (pt) | 2005-11-18 | 2021-07-27 | The Government Of The United State Of America Representado Por The Secretary Of The Dept Of Health A | cardiolipina modificada e seus usos |
JP4629563B2 (ja) * | 2005-12-07 | 2011-02-09 | 積水メディカル株式会社 | 抗リン脂質抗体測定試薬 |
WO2007066731A1 (ja) * | 2005-12-07 | 2007-06-14 | Sekisui Medical Co., Ltd. | 抗リン脂質抗体測定試薬及び抗トレポネーマ・パリダム抗体測定試薬 |
CN102095861A (zh) * | 2011-01-25 | 2011-06-15 | 厦门大学附属中山医院 | 梅毒特异性总抗体和心磷脂抗体免疫印迹试剂盒及其制备 |
RU2474820C2 (ru) * | 2011-04-11 | 2013-02-10 | Виктория Олеговна Пожарская | Способ контроля эффективности лечения сифилиса |
US8945827B2 (en) | 2013-03-13 | 2015-02-03 | Awareness Technology, Inc. | Serological methods and diagnostic tests for syphilis antibodies |
CN104049081B (zh) * | 2013-03-13 | 2016-03-09 | 意识科技股份有限公司 | 针对梅毒抗体的血清学方法和诊断测试 |
GB201400819D0 (en) | 2014-01-17 | 2014-03-05 | Sec Dep For Health The | Mycobacterial antigen composition |
WO2016144962A1 (en) | 2015-03-10 | 2016-09-15 | Bio-Rad Laboratories, Inc. | Combination treponemal and non-treponemal syphilis test |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1053504A (pt) * | 1964-03-17 | 1967-01-04 | ||
EP0009088A1 (de) * | 1978-09-18 | 1980-04-02 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Reagenz zur Bestimmung von Wassermann-Antikörpern, Verfahren zu dessen Herstellung, Anwendung und Verwendung dieses Reagenzes zur Bestimmung von Wassermann-Antikörpern sowie entsprechende Reagenziengarnitur |
-
2000
- 2000-06-08 CN CNB008085404A patent/CN1195986C/zh not_active Expired - Lifetime
- 2000-06-08 EP EP00939708A patent/EP1185872B1/en not_active Expired - Lifetime
- 2000-06-08 AU AU54756/00A patent/AU771548B2/en not_active Expired
- 2000-06-08 RU RU2001135795/15A patent/RU2244933C2/ru active
- 2000-06-08 DE DE60025605T patent/DE60025605T2/de not_active Expired - Lifetime
- 2000-06-08 WO PCT/US2000/015828 patent/WO2000075666A1/en active IP Right Grant
- 2000-06-08 BR BRPI0011449A patent/BRPI0011449B8/pt not_active IP Right Cessation
- 2000-06-08 CA CA002375448A patent/CA2375448C/en not_active Expired - Lifetime
- 2000-06-08 AT AT00939708T patent/ATE316245T1/de active
- 2000-06-08 JP JP2001501890A patent/JP4531314B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2003501662A (ja) | 2003-01-14 |
CN1353815A (zh) | 2002-06-12 |
CN1195986C (zh) | 2005-04-06 |
DE60025605T2 (de) | 2006-11-09 |
AU771548B2 (en) | 2004-03-25 |
DE60025605D1 (de) | 2006-04-06 |
ATE316245T1 (de) | 2006-02-15 |
BR0011449A (pt) | 2002-03-19 |
RU2244933C2 (ru) | 2005-01-20 |
CA2375448C (en) | 2009-04-07 |
JP4531314B2 (ja) | 2010-08-25 |
CA2375448A1 (en) | 2000-12-14 |
EP1185872B1 (en) | 2006-01-18 |
BR0011449B1 (pt) | 2013-12-03 |
AU5475600A (en) | 2000-12-28 |
WO2000075666A1 (en) | 2000-12-14 |
EP1185872A1 (en) | 2002-03-13 |
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