BR9909105A - Terapia de distúrbios associados ao estrogênio descrição - Google Patents
Terapia de distúrbios associados ao estrogênio descriçãoInfo
- Publication number
- BR9909105A BR9909105A BR9909105-4A BR9909105A BR9909105A BR 9909105 A BR9909105 A BR 9909105A BR 9909105 A BR9909105 A BR 9909105A BR 9909105 A BR9909105 A BR 9909105A
- Authority
- BR
- Brazil
- Prior art keywords
- estrogen
- therapy
- associated disorders
- description
- isoflavone
- Prior art date
Links
- 229940011871 estrogen Drugs 0.000 title abstract 3
- 239000000262 estrogen Substances 0.000 title abstract 3
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 239000000284 extract Substances 0.000 abstract 3
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 abstract 3
- 235000008696 isoflavones Nutrition 0.000 abstract 3
- ZQSIJRDFPHDXIC-UHFFFAOYSA-N daidzein Chemical compound C1=CC(O)=CC=C1C1=COC2=CC(O)=CC=C2C1=O ZQSIJRDFPHDXIC-UHFFFAOYSA-N 0.000 abstract 2
- HKQYGTCOTHHOMP-UHFFFAOYSA-N formononetin Chemical compound C1=CC(OC)=CC=C1C1=COC2=CC(O)=CC=C2C1=O HKQYGTCOTHHOMP-UHFFFAOYSA-N 0.000 abstract 2
- GOMNOOKGLZYEJT-UHFFFAOYSA-N isoflavone Chemical compound C=1OC2=CC=CC=C2C(=O)C=1C1=CC=CC=C1 GOMNOOKGLZYEJT-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229930191576 Biochanin Natural products 0.000 abstract 1
- 235000010523 Cicer arietinum Nutrition 0.000 abstract 1
- 244000045195 Cicer arietinum Species 0.000 abstract 1
- 241000219793 Trifolium Species 0.000 abstract 1
- WUADCCWRTIWANL-UHFFFAOYSA-N biochanin A Chemical compound C1=CC(OC)=CC=C1C1=COC2=CC(O)=CC(O)=C2C1=O WUADCCWRTIWANL-UHFFFAOYSA-N 0.000 abstract 1
- 235000007240 daidzein Nutrition 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- RIKPNWPEMPODJD-UHFFFAOYSA-N formononetin Natural products C1=CC(OC)=CC=C1C1=COC2=CC=CC=C2C1=O RIKPNWPEMPODJD-UHFFFAOYSA-N 0.000 abstract 1
- ZCOLJUOHXJRHDI-CMWLGVBASA-N genistein 7-O-beta-D-glucoside Chemical group O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 ZCOLJUOHXJRHDI-CMWLGVBASA-N 0.000 abstract 1
- 150000002515 isoflavone derivatives Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000003637 steroidlike Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Alternative & Traditional Medicine (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
<B>TERAPIA DE DISTúRBIOS ASSOCIADOS AO ESTROGêNIO DESCRIçãO<D> é descrito um método para o tratamento, profilaxia, alívio ou prevenção de distúrbios associados com atividade anormalmente alta de estrogênios esteroidais, o qual inclui a administração a um indivíduo humano de uma composição compreendendo um extrato contendo isoflavona de trevo ou grão-de-bico, o referido extrato compreendendo primariamente biochanina, ou uma proporção de biochanina em relação a uma ou mais das isoflavonas do grupo formononetina, daidzeína e genisteína variando de cerca de 2:1 a cerca de 5:1, opcionalmente em associação com um ou mais transportadores, excipientes, auxiliares e/ou diluentes farmaceuticamente aceitáveis. Também são descritas composições e uso compreendendo os extratos que contêm isoflavona.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPP2607A AUPP260798A0 (en) | 1998-03-26 | 1998-03-26 | Treatment of medical related conditions with isoflavone containing extracts of clover |
PCT/AU1999/000222 WO1999048496A1 (en) | 1998-03-26 | 1999-03-26 | Therapy of estrogen-associated disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9909105A true BR9909105A (pt) | 2000-12-05 |
Family
ID=3806868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9909105-4A BR9909105A (pt) | 1998-03-26 | 1999-03-26 | Terapia de distúrbios associados ao estrogênio descrição |
Country Status (16)
Country | Link |
---|---|
US (3) | US6599536B1 (pt) |
EP (1) | EP1063990B1 (pt) |
JP (1) | JP2002507568A (pt) |
AU (1) | AUPP260798A0 (pt) |
BR (1) | BR9909105A (pt) |
CA (1) | CA2325631A1 (pt) |
DE (1) | DE69934877T2 (pt) |
DK (1) | DK1063990T3 (pt) |
ES (1) | ES2281169T3 (pt) |
IL (1) | IL138129A (pt) |
NO (1) | NO325456B1 (pt) |
NZ (1) | NZ506701A (pt) |
PT (1) | PT1063990E (pt) |
TR (1) | TR200002770T2 (pt) |
WO (1) | WO1999048496A1 (pt) |
ZA (1) | ZA200005070B (pt) |
Families Citing this family (33)
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---|---|---|---|---|
US5830887A (en) * | 1992-05-19 | 1998-11-03 | Novogen Research Pty. Ltd. | Health supplements containing phyto-oestrogens, analogues or metabolites thereof |
AUPO203996A0 (en) | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
US6146668A (en) | 1997-04-28 | 2000-11-14 | Novogen, Inc. | Preparation of isoflavones from legumes |
US6340703B1 (en) * | 1997-05-01 | 2002-01-22 | Novogen, Inc. | Treatment or prevention of osteoporosis |
AUPP112497A0 (en) * | 1997-12-24 | 1998-01-22 | Novogen Research Pty Ltd | Compositions and method for protecting skin from UV induced immunosupression and skin damage |
AUPP260798A0 (en) * | 1998-03-26 | 1998-04-23 | Novogen Research Pty Ltd | Treatment of medical related conditions with isoflavone containing extracts of clover |
AUPQ008399A0 (en) * | 1999-04-28 | 1999-05-27 | Novogen Research Pty Ltd | Cariovascular applications |
AU761047B2 (en) * | 1999-04-28 | 2003-05-29 | Novogen Research Pty Ltd | Cardiovascular and bone treatment using isoflavones |
AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
US20090233999A1 (en) * | 1999-09-06 | 2009-09-17 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
US20040213859A1 (en) * | 1999-09-17 | 2004-10-28 | Zelickson Brian D. | Organic nutrient for hair loss treatment |
AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
EP1174144A1 (en) * | 2000-07-20 | 2002-01-23 | Linnea S.A. | Dry extract rich in isoflavones and process of preparation |
AUPR255401A0 (en) * | 2001-01-16 | 2001-02-08 | Novogen Research Pty Ltd | Regulation of lipids and/or bone density and compositions therefor |
AUPR363301A0 (en) * | 2001-03-08 | 2001-04-05 | Novogen Research Pty Ltd | Dimeric isoflavones |
DE10114305A1 (de) * | 2001-03-23 | 2002-09-26 | Beiersdorf Ag | Kosmetische und dermatologische Zubereitungen mit einem Gehalt an Isoflavonen und Verwendung von Isoflavonen zur Herstellung kosmetischer und dermatologischer Zubereitungen zur Reduktion des Sebumgehaltes der Haut |
DE50211883D1 (de) * | 2002-04-30 | 2008-04-24 | Cognis Ip Man Gmbh | Verwendung von Wirkstoffmischungen mit Azelainsäure und Glycyrrhetinsäure als Anti-Aknemittel |
US8668914B2 (en) * | 2002-07-24 | 2014-03-11 | Brigham Young University | Use of equol for treating skin diseases |
WO2004039327A2 (en) * | 2002-10-29 | 2004-05-13 | Colorado State University Research Foundation | Use of equol for treating androgen mediated diseases |
US20050245492A1 (en) * | 2004-04-28 | 2005-11-03 | Lephart Edwin D | Use of equol for treating skin diseases |
CN1681386B (zh) | 2002-07-24 | 2010-05-26 | 儿童医院医疗中心 | 含有对映体牛尿酚的组合物和产物及其制备方法 |
AU2003255232A1 (en) * | 2002-08-07 | 2004-02-25 | University Of Mississippi | Antigiardial agents and use thereof |
US8580846B2 (en) | 2002-10-29 | 2013-11-12 | Brigham Young University | Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders |
US20060039971A1 (en) * | 2004-08-19 | 2006-02-23 | Lee Robert E | Effervescent composition including alternative hormone replacement therapy agent |
EP1842541A1 (en) | 2006-03-29 | 2007-10-10 | G.I.M.-Gesellschaft Für Innovative Medizin Gmbh Nfg Ohg | Plant components and extracts and uses thereof |
US20110091435A1 (en) * | 2008-10-24 | 2011-04-21 | University Of Southern California | Phytoestrogenic formulations for alleviation or prevention of hair loss |
US10307451B2 (en) * | 2010-02-15 | 2019-06-04 | Sinoveda Canada Inc. | Phytoestrogen product of red clover and pharmaceutical uses thereof |
JP2014169286A (ja) * | 2013-02-07 | 2014-09-18 | Shiga Univ Of Medical Science | 子宮筋腫に伴う子宮出血抑制用医薬 |
JP6985656B2 (ja) * | 2017-02-28 | 2021-12-22 | ニチモウ株式会社 | 子宮内膜症改善用組成物およびその製造方法 |
JP7281156B2 (ja) * | 2018-05-16 | 2023-05-25 | 共栄化学工業株式会社 | 皮膚外用剤 |
CN111838198B (zh) * | 2020-08-17 | 2021-07-02 | 南通大学 | 鹰嘴豆提取物在防治农作物病原细菌中的应用 |
WO2022250488A1 (ko) * | 2021-05-28 | 2022-12-01 | 연세대학교 산학협력단 | 난소내막종의 예방 또는 치료용 조성물 |
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AUPP260798A0 (en) * | 1998-03-26 | 1998-04-23 | Novogen Research Pty Ltd | Treatment of medical related conditions with isoflavone containing extracts of clover |
FR2781154B1 (fr) | 1998-07-15 | 2001-09-07 | Lafon Labor | Composition therapeutique a base d'isoflavonoides destinee a etre utilisee dans le traitement des tumeurs par des agents cytotoxiques |
AUPP868599A0 (en) * | 1999-02-15 | 1999-03-11 | Novogen Research Pty Ltd | Production of isoflavone derivatives |
US20040072765A1 (en) * | 1999-04-28 | 2004-04-15 | Novogen Research Pty Ltd. | Cardiovascular and bone treatment using isoflavones |
AUPQ266199A0 (en) * | 1999-09-06 | 1999-09-30 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
AUPQ520300A0 (en) * | 2000-01-21 | 2000-02-17 | Novogen Research Pty Ltd | Food product and process |
AUPR255401A0 (en) * | 2001-01-16 | 2001-02-08 | Novogen Research Pty Ltd | Regulation of lipids and/or bone density and compositions therefor |
AUPR846401A0 (en) * | 2001-10-25 | 2001-11-15 | Novogen Research Pty Ltd | 6-Hydroxy isoflavones, derivatives and medicaments involving same |
-
1998
- 1998-03-26 AU AUPP2607A patent/AUPP260798A0/en not_active Abandoned
-
1999
- 1999-03-26 NZ NZ506701A patent/NZ506701A/en unknown
- 1999-03-26 IL IL13812999A patent/IL138129A/xx not_active IP Right Cessation
- 1999-03-26 DK DK99912976T patent/DK1063990T3/da active
- 1999-03-26 EP EP99912976A patent/EP1063990B1/en not_active Expired - Lifetime
- 1999-03-26 TR TR2000/02770T patent/TR200002770T2/xx unknown
- 1999-03-26 US US09/647,092 patent/US6599536B1/en not_active Expired - Fee Related
- 1999-03-26 PT PT99912976T patent/PT1063990E/pt unknown
- 1999-03-26 WO PCT/AU1999/000222 patent/WO1999048496A1/en active IP Right Grant
- 1999-03-26 JP JP2000537544A patent/JP2002507568A/ja active Pending
- 1999-03-26 BR BR9909105-4A patent/BR9909105A/pt not_active Application Discontinuation
- 1999-03-26 DE DE69934877T patent/DE69934877T2/de not_active Expired - Fee Related
- 1999-03-26 CA CA002325631A patent/CA2325631A1/en not_active Abandoned
- 1999-03-26 ES ES99912976T patent/ES2281169T3/es not_active Expired - Lifetime
-
2000
- 2000-09-19 NO NO20004688A patent/NO325456B1/no not_active IP Right Cessation
- 2000-09-21 ZA ZA200005070A patent/ZA200005070B/en unknown
-
2003
- 2003-06-12 US US10/459,537 patent/US20030219499A1/en not_active Abandoned
-
2007
- 2007-04-17 US US11/785,298 patent/US20080038387A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69934877D1 (de) | 2007-03-08 |
ZA200005070B (en) | 2001-12-21 |
US20030219499A1 (en) | 2003-11-27 |
JP2002507568A (ja) | 2002-03-12 |
NZ506701A (en) | 2003-07-25 |
EP1063990B1 (en) | 2007-01-17 |
EP1063990A4 (en) | 2003-01-02 |
NO325456B1 (no) | 2008-05-05 |
IL138129A (en) | 2005-06-19 |
PT1063990E (pt) | 2007-04-30 |
AUPP260798A0 (en) | 1998-04-23 |
NO20004688D0 (no) | 2000-09-19 |
TR200002770T2 (tr) | 2000-11-21 |
WO1999048496A1 (en) | 1999-09-30 |
EP1063990A1 (en) | 2001-01-03 |
NO20004688L (no) | 2000-09-19 |
DK1063990T3 (da) | 2007-05-21 |
US6599536B1 (en) | 2003-07-29 |
CA2325631A1 (en) | 1999-09-30 |
IL138129A0 (en) | 2001-10-31 |
ES2281169T3 (es) | 2007-09-16 |
US20080038387A1 (en) | 2008-02-14 |
DE69934877T2 (de) | 2007-11-08 |
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Legal Events
Date | Code | Title | Description |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE DE ACORDO COM ART. 8O DA LPI |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/35 (2006.01), A61K 36/48 (2006.0 |