BR9806822A - Método para a produção de ácidos dicarboxìlicos. - Google Patents

Método para a produção de ácidos dicarboxìlicos.

Info

Publication number
BR9806822A
BR9806822A BR9806822-9A BR9806822A BR9806822A BR 9806822 A BR9806822 A BR 9806822A BR 9806822 A BR9806822 A BR 9806822A BR 9806822 A BR9806822 A BR 9806822A
Authority
BR
Brazil
Prior art keywords
organism
carbon source
atmosphere
production
maintain
Prior art date
Application number
BR9806822-9A
Other languages
English (en)
Other versions
BR9806822B1 (pt
Inventor
Nhuan Phu Nghiem
Mark Donnelly
Cynthia S Millard
Lucy Stols
Original Assignee
Lockheed Martin Energy Res Cor
Univ Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lockheed Martin Energy Res Cor, Univ Chicago filed Critical Lockheed Martin Energy Res Cor
Publication of BR9806822A publication Critical patent/BR9806822A/pt
Publication of BR9806822B1 publication Critical patent/BR9806822B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/46Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/848Escherichia
    • Y10S435/849Escherichia coli
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/853Lactobacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"MéTODO PARA A PRODUçãO DE áCIDOS DICARBOXìLICOS". A presente invenção é um método de fermentação económico, para a produção de ácidos carboxílicos, compreendendo as etapas de : a) inocular um meio tendo uma fonte de carbono com um organismo produtor de ácido carboxílico; b) incubar o organismo produtor de ácido carboxílico em uma atmosfera aeróbica, para promover o rápido desenvolvimento do organismo, desse modo aumentando a biomassa do organismo; c) liberar de forma controlável o oxigênio, para manter a atmosfera aeróbica; d) alimentar de forma controlável o organismo tendo biomassa aumentada com uma solução contendo a fotne de carbono, para manter a concentração da fonte de carbono dentro do meio de cerca de 0,5 g/l até cerca de 1 g/l e) excluir a atmosfera aeróbica de oxigênio para produzir uma atmosfera anaeróbica, para fazer com que o organismo sofra metabolismo anaeróbico; f) alimentar de forma controlável o organismo tendo biomassa aumentada com uma solução contendo a fonte de carbono, para manter a concentração da fonte de carbono dentro do meio ( 1 g/l; e g) converter a fonte de carbono em ácidos carboxílicos, usando o metabolismo anaeróbico do organismo.
BRPI9806822-9A 1997-01-31 1998-01-30 método para a produção de ácidos dicarboxìlicos. BR9806822B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/792,655 US5869301A (en) 1995-11-02 1997-01-31 Method for the production of dicarboxylic acids
PCT/US1998/001877 WO1998033930A1 (en) 1997-01-31 1998-01-30 A method for the production of dicarboxylic acids

Publications (2)

Publication Number Publication Date
BR9806822A true BR9806822A (pt) 2000-05-09
BR9806822B1 BR9806822B1 (pt) 2009-05-05

Family

ID=25157624

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9806822-9A BR9806822B1 (pt) 1997-01-31 1998-01-30 método para a produção de ácidos dicarboxìlicos.

Country Status (14)

Country Link
US (1) US5869301A (pt)
EP (1) EP1012323B1 (pt)
JP (1) JP3681404B2 (pt)
CN (1) CN1121500C (pt)
AT (1) ATE360084T1 (pt)
AU (1) AU724274B2 (pt)
BR (1) BR9806822B1 (pt)
CA (1) CA2278892C (pt)
DE (1) DE69837607T2 (pt)
DK (1) DK1012323T3 (pt)
ES (1) ES2285757T3 (pt)
HU (1) HU227509B1 (pt)
PT (1) PT1012323E (pt)
WO (1) WO1998033930A1 (pt)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10129711B4 (de) * 2001-06-22 2007-08-23 Forschungszentrum Jülich GmbH Verfahren zur fermentativen Herstellung von Pyruvat
US8183350B2 (en) 2002-05-04 2012-05-22 Acorda Therapeutics, Inc. Compositions and methods for promoting neuronal outgrowth
DE10220234B4 (de) * 2002-05-06 2013-05-23 Forschungszentrum Jülich GmbH Verfahren sowie Mikroorganismen zur mikrobiellen Herstellung von Pyruvat aus Kohlenhydraten sowie Alkoholen
WO2004017044A2 (en) * 2002-08-15 2004-02-26 Acorda Therapeutics, Inc. Chimeric protein
US7959914B2 (en) 2003-05-16 2011-06-14 Acorda Therapeutics, Inc. Methods of reducing extravasation of inflammatory cells
CA2525804C (en) * 2003-05-16 2017-04-25 Acorda Therapeutics, Inc. Use of chondroitinase abc enzyme for the treatment of cns injuries
AU2004247026B2 (en) * 2003-05-16 2009-09-24 Acorda Therapeutics, Inc. Proteoglycan degrading mutants for treatment of CNS
JP4469568B2 (ja) * 2003-07-09 2010-05-26 三菱化学株式会社 有機酸の製造方法
WO2005010182A1 (ja) * 2003-07-29 2005-02-03 Research Institute Of Innovative Technology For The Earth コリネ型細菌形質転換体及びそれを用いるジカルボン酸の製造方法
EP1672077B1 (en) * 2003-08-28 2015-01-21 Mitsubishi Chemical Corporation Process for producing succinic acid
EP1672067B1 (en) * 2003-09-17 2015-11-11 Mitsubishi Chemical Corporation Process for producing non-amino organic acid
JP4631706B2 (ja) * 2003-09-30 2011-02-16 味の素株式会社 発酵液からのコハク酸の精製方法
WO2005045049A1 (ja) * 2003-11-07 2005-05-19 Mitsubishi Chemical Corporation 有機酸アンモニウム溶液の製造方法
JP2005295998A (ja) * 2003-11-07 2005-10-27 Mitsubishi Chemicals Corp 有機酸アンモニウム溶液の製造方法
WO2005112986A2 (en) * 2004-05-18 2005-12-01 Acorda Therapeutics, Inc. Purifying chondroitinase and stable formulations thereof
CN1989239B (zh) * 2004-05-20 2013-07-10 味之素株式会社 生产琥珀酸的细菌和生产琥珀酸的方法
BRPI0510919A (pt) * 2004-05-20 2008-05-20 Ajinomoto Kk bactéria produtora de ácido succìnico e processo para produzir ácido succìnico
EP3130676A1 (en) 2004-08-27 2017-02-15 Rice University Mutant e. coli strain with increased succinic acid production
WO2006034156A2 (en) * 2004-09-17 2006-03-30 Rice University High succinate producing bacteria
JP4537862B2 (ja) * 2005-01-18 2010-09-08 財団法人地球環境産業技術研究機構 好気性細菌による高効率な有機酸の製造方法
EP3925996A3 (en) 2005-04-22 2022-04-20 Mitsubishi Chemical Corporation Biomass-resource-derived polyester and production process thereof
JP4380654B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
JP4380653B2 (ja) * 2005-04-22 2009-12-09 三菱化学株式会社 ポリエステル及びその製造方法
US20070111294A1 (en) * 2005-09-09 2007-05-17 Genomatica, Inc. Methods and organisms for the growth-coupled production of succinate
ES2393748T3 (es) 2005-09-26 2012-12-27 Acorda Therapeutics, Inc. Composiciones y métodos de uso de condroitinasa ABCI mutantes
BRPI0617491B1 (pt) * 2005-10-18 2021-04-27 Ajinomoto Co., Inc Processo para produção de ácido succínico
US7335066B2 (en) * 2005-12-16 2008-02-26 James A. Carroll Network connector and connection system
US7993888B2 (en) * 2006-02-24 2011-08-09 Mitsubishi Chemical Corporation Bacterium having enhanced 2-oxoglutarate dehydrogenase activity
EP1842843A1 (de) * 2006-04-04 2007-10-10 Basf Aktiengesellschaft Verfahren zur Herstellung eines Carbonsäurealkylesters
CN104962586A (zh) 2006-07-21 2015-10-07 希乐克公司 生物质转化***
CA3009034C (en) 2006-10-10 2020-08-18 Acorda Therapeutics, Inc. Compositions and methods of using chondroitinase abci mutants
WO2008091627A2 (en) * 2007-01-22 2008-07-31 Genomatica, Inc. Methods and organisms for growth-coupled production of 3-hydroxypropionic acid
LT2821494T (lt) 2007-03-16 2017-04-25 Genomatica, Inc. 1,4-butandiolio ir jo pirmtakų biosintezės būdai ir kompozicijos
KR101631719B1 (ko) * 2007-03-20 2016-06-24 유니버시티 오브 플로리다 리서치 파운데이션, 인크. 유효한 숙시네이트 및 말레이트 제조를 위한 물질 및 방법
DE102007019184A1 (de) 2007-04-20 2008-10-23 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
DK2164975T3 (da) 2007-07-06 2012-05-29 Basf Se Fremgangsmåde til fremstilling af en koncentreret vandig glukoseopløsning af majs
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
WO2009045637A2 (en) * 2007-08-10 2009-04-09 Genomatica, Inc. Methods for the synthesis of acrylic acid and derivatives from fumaric acid
US8735112B2 (en) * 2007-11-20 2014-05-27 Dsm Ip Assets B.V. Dicarboxylic acid production in a recombinant yeast
FR2925068B1 (fr) * 2007-12-13 2010-01-08 Roquette Freres Procedes de production d'acide succinique
BRPI0722315A2 (pt) * 2007-12-28 2014-06-10 Roquette Freres Método de cultura microbiana em larga escala
JP2011509691A (ja) 2008-01-22 2011-03-31 ジェノマティカ, インコーポレイテッド 合成ガスまたは他のガス状炭素源およびメタノールを利用するための方法および生物体
EP2262901B1 (en) 2008-03-05 2018-11-21 Genomatica, Inc. Primary alcohol producing organisms
CN102066551B (zh) 2008-03-27 2013-10-09 基因组股份公司 用于产生己二酸和其他化合物的微生物
JP2011519561A (ja) 2008-05-01 2011-07-14 ジェノマティカ, インコーポレイテッド メタクリル酸の産生のための微生物
EP2304039B1 (en) * 2008-06-17 2019-08-21 Genomatica, Inc. Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate
CN107267562A (zh) 2008-07-08 2017-10-20 帝斯曼知识产权资产管理有限公司 通过在低pH下发酵生产二羧酸
US20100021978A1 (en) * 2008-07-23 2010-01-28 Genomatica, Inc. Methods and organisms for production of 3-hydroxypropionic acid
WO2010030711A2 (en) 2008-09-10 2010-03-18 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
DE102008051727A1 (de) 2008-10-17 2010-04-22 Organo Balance Gmbh Mikroorganismus zur Herstellung von Bernsteinsäure
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
AU2009327490A1 (en) * 2008-12-16 2011-07-28 Genomatica, Inc. Microorganisms and methods for conversion of syngas and other carbon sources to useful products
FR2941959B1 (fr) * 2009-02-12 2013-06-07 Roquette Freres Procedes de production d'acide succinique
JP2012522515A (ja) 2009-04-02 2012-09-27 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド コハク酸生産経路の工学処理
JP2012525156A (ja) 2009-04-30 2012-10-22 ゲノマチカ, インク. イソプロパノール、n−ブタノール、及びイソブタノールの産生のための微生物
US9017983B2 (en) * 2009-04-30 2015-04-28 Genomatica, Inc. Organisms for the production of 1,3-butanediol
JP5773990B2 (ja) 2009-05-07 2015-09-02 ゲノマチカ, インク. アジペート、ヘキサメチレンジアミン、及び6−アミノカプロン酸の生合成のための微生物及び方法
WO2010132845A1 (en) * 2009-05-15 2010-11-18 Genomatica, Inc. Organisms for the production of cyclohexanone
CN107384846B (zh) 2009-06-04 2021-08-10 基因组股份公司 生产1,4-丁二醇的微生物和相关方法
CA2764368C (en) * 2009-06-04 2017-08-01 Genomatica, Inc. Process of separating components of a fermentation broth
EP2440669A4 (en) * 2009-06-10 2013-08-28 Genomatica Inc MICROOGANISMS AND PROCEDURES FOR THE CARBON EFFECTIVE BIOSYNTHESIS MEK AND 2-BUTANOL
WO2011017560A1 (en) 2009-08-05 2011-02-10 Genomatica, Inc. Semi-synthetic terephthalic acid via microorganisms that produce muconic acid
EA026438B1 (ru) * 2009-08-27 2017-04-28 ДСМ АйПи АССЕТС Б.В. Способ ферментативного получения дикарбоновых кислот
JP2013504326A (ja) 2009-09-09 2013-02-07 ジェノマティカ・インコーポレイテッド イソプロパノールならびに第一級アルコール、ジオールおよび酸の共生成のための微生物ならびに方法
CN105441374A (zh) * 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
KR20180014240A (ko) 2009-10-23 2018-02-07 게노마티카 인코포레이티드 아닐린의 제조를 위한 미생물
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
WO2011071682A1 (en) 2009-12-10 2011-06-16 Genomatica, Inc. Methods and organisms for converting synthesis gas or other gaseous carbon sources and methanol to 1,3-butanediol
MX2012008738A (es) * 2010-01-29 2012-08-31 Genomatica Inc Microorganismos y metodos para la biosintesis de p-toluato y tereftalato.
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8637286B2 (en) * 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
US9023636B2 (en) 2010-04-30 2015-05-05 Genomatica, Inc. Microorganisms and methods for the biosynthesis of propylene
WO2011140171A2 (en) 2010-05-05 2011-11-10 Genomatica, Inc. Microorganisms and methods for the biosynthesis of butadiene
US20110306734A1 (en) 2010-06-02 2011-12-15 Bayer Materialscience Ag Thermoplastically processable polyurethanes based on succinic acid propionates
CN103038302B (zh) 2010-06-08 2014-07-09 由俄勒冈州高等教育管理委员会代表的俄勒冈州立大学 植物油基压敏粘合剂
MX2013001071A (es) 2010-07-26 2013-06-28 Genomatica Inc Microorganismos y metodos para la biosintesis de aromaticos, 2, 4-pentadienoato y 1, 3-butadieno.
EP2686293A1 (en) 2011-03-14 2014-01-22 Dow Global Technologies LLC Processes for producing terephthalic acid and terephthalic esters
CN102242074B (zh) * 2011-04-12 2014-08-06 叶春 一种兼性厌氧菌的筛选方法
US8580096B2 (en) 2011-09-29 2013-11-12 Uchicago Argonne, Llc Bioprocess utilizing carbon dioxide and electrodeionization
WO2013045546A1 (de) 2011-09-30 2013-04-04 Bayer Intellectual Property Gmbh Homogene extrudierte artikel aus thermoplastisch verarbeitbaren polyurethanen auf basis von polyesterdiolen aus bernsteinsäure und 1,3 -propandiol
AU2012376541B2 (en) 2012-04-09 2016-05-12 Avery Dennison Corporation Pressure sensitive adhesives based on renewable resources, UV curing and related methods
WO2013166075A1 (en) 2012-04-30 2013-11-07 Woods Hole Oceanographic Institution Cobalamin acquisition protein and use thereof
WO2013184602A2 (en) 2012-06-04 2013-12-12 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
WO2017192925A1 (en) * 2016-05-05 2017-11-09 William Marsh Rice University Improved microbial production of fats
CN110951660B (zh) * 2019-12-19 2021-12-03 江南大学 一株固定co2产苹果酸的大肠杆菌工程菌的构建及应用
CN114350718B (zh) * 2021-12-31 2024-06-07 安徽丰原发酵技术工程研究有限公司 一种发酵生产苹果酸的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5543759B2 (pt) * 1972-06-28 1980-11-07
US4190495A (en) * 1976-09-27 1980-02-26 Research Corporation Modified microorganisms and method of preparing and using same
JPS60114197A (ja) * 1983-11-25 1985-06-20 Agency Of Ind Science & Technol 微生物によるジカルボン酸の製造法
US4871667A (en) * 1984-11-26 1989-10-03 Agency Of Industrial Science & Technology Process for preparing muconic acid
US5143834A (en) * 1986-06-11 1992-09-01 Glassner David A Process for the production and purification of succinic acid
US5168055A (en) * 1986-06-11 1992-12-01 Rathin Datta Fermentation and purification process for succinic acid
EP0249773B1 (en) * 1986-06-11 1992-12-16 Michigan Biotechnology Institute A process for the production of succinic acid by anaerobic fermentation
US5182199A (en) * 1987-05-27 1993-01-26 Hartley Brian S Thermophilic ethanol production in a two-stage closed system
WO1990012888A1 (en) * 1989-04-27 1990-11-01 Biocontrol Systems, Incorporated Precipitate test for microorganisms
US5416020A (en) * 1992-09-29 1995-05-16 Bio-Technical Resources Lactobacillus delbrueckii ssp. bulgaricus strain and fermentation process for producing L-(+)-lactic acid
FR2702492B1 (fr) * 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
NZ267894A (en) * 1993-06-25 1997-10-24 Du Pont Enzymatic preparation of pyruvic acid
WO1995001449A1 (en) * 1993-07-01 1995-01-12 E.I. Du Pont De Nemours And Company An improved method of preparing glyoxylic acid/aminomethylphosphonic acid mixtures using a microbial double-transformant
US5521075A (en) * 1994-12-19 1996-05-28 Michigan Biotechnology Institute Method for making succinic acid, anaerobiospirillum succiniciproducens variants for use in process and methods for obtaining variants
US5504004A (en) * 1994-12-20 1996-04-02 Michigan Biotechnology Institute Process for making succinic acid, microorganisms for use in the process and methods of obtaining the microorganisms

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JP2000515389A (ja) 2000-11-21
EP1012323A4 (en) 2002-01-16
AU724274B2 (en) 2000-09-14
EP1012323A1 (en) 2000-06-28
DE69837607D1 (de) 2007-05-31
DE69837607T2 (de) 2007-12-27
HUP0001997A2 (hu) 2000-10-28
BR9806822B1 (pt) 2009-05-05
DK1012323T3 (da) 2007-06-18
CN1121500C (zh) 2003-09-17
ATE360084T1 (de) 2007-05-15
CA2278892C (en) 2009-02-24
US5869301A (en) 1999-02-09
PT1012323E (pt) 2007-05-31
CN1246155A (zh) 2000-03-01
AU6052398A (en) 1998-08-25
WO1998033930A1 (en) 1998-08-06
HU227509B1 (en) 2011-07-28
EP1012323B1 (en) 2007-04-18
CA2278892A1 (en) 1998-08-06
JP3681404B2 (ja) 2005-08-10
ES2285757T3 (es) 2007-11-16
HUP0001997A3 (en) 2002-01-28

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