BR9605267A - Inibidor de angiogenese - Google Patents
Inibidor de angiogeneseInfo
- Publication number
- BR9605267A BR9605267A BR9605267A BR9605267A BR9605267A BR 9605267 A BR9605267 A BR 9605267A BR 9605267 A BR9605267 A BR 9605267A BR 9605267 A BR9605267 A BR 9605267A BR 9605267 A BR9605267 A BR 9605267A
- Authority
- BR
- Brazil
- Prior art keywords
- angiogenesis inhibitor
- angiogenesis
- inhibitor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27748595 | 1995-10-25 | ||
JP24804696 | 1996-09-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9605267A true BR9605267A (pt) | 1998-07-21 |
Family
ID=26538555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9605267A BR9605267A (pt) | 1995-10-25 | 1996-10-25 | Inibidor de angiogenese |
Country Status (13)
Country | Link |
---|---|
US (2) | US6057290A (pt) |
EP (2) | EP0927716B1 (pt) |
AR (1) | AR004694A1 (pt) |
AT (3) | ATE230275T1 (pt) |
AU (1) | AU716495B2 (pt) |
BR (1) | BR9605267A (pt) |
CA (1) | CA2188817C (pt) |
DE (3) | DE69625575T2 (pt) |
ES (2) | ES2190139T3 (pt) |
HU (1) | HUP9602943A3 (pt) |
MX (1) | MX9605156A (pt) |
NO (1) | NO964514L (pt) |
PL (1) | PL316669A1 (pt) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997003060A1 (fr) * | 1995-07-13 | 1997-01-30 | Senju Pharmaceutical Co., Ltd. | Derives de la piperazine et leurs utilisations |
US6214800B1 (en) * | 1995-10-25 | 2001-04-10 | Senju Pharmaceutical Co., Ltd. | Angiogenesis inhibitor |
DE19718826A1 (de) * | 1997-05-05 | 1998-11-12 | Marion S Dr Eckmiller | Verwendung biologisch aktiver Wirkstoffe zum Beeinflussen des Extrazellulär-Raumes von Sinneszellen und Verfahren zur Wirkstoff-Administrationssteuerung |
WO1999011640A1 (fr) * | 1997-09-04 | 1999-03-11 | Nippon Chemiphar Co., Ltd. | Derives d'epoxysuccinamide |
US6015787A (en) * | 1997-11-04 | 2000-01-18 | New England Medical Center Hospitals, Inc. | Cell-permeable protein inhibitors of calpain |
DE69925578T2 (de) | 1998-03-05 | 2006-04-27 | Senju Pharmaceutical Co., Ltd. | Pharmazeutische zusammenstellung zur vorbeugung und behandlung von mit zellkrankheiten des augenhintergrundes zusammenhängenden krankheiten |
KR20010041967A (ko) | 1998-03-20 | 2001-05-25 | 요시다 쇼지 | 뇌조직 장애를 예방 및 치료하기 위한 시스테인프로테아제 억제제 함유 약제학적 조성물 |
GB9819860D0 (en) * | 1998-09-12 | 1998-11-04 | Zeneca Ltd | Chemical compounds |
CN1398189A (zh) | 1998-12-23 | 2003-02-19 | G.D.西尔公司 | 用于***形成的放疗与cox-2抑制剂的联合治疗 |
WO2000058280A1 (fr) * | 1999-03-26 | 2000-10-05 | Shionogi & Co., Ltd. | Derives de sulfonamide carbocyclique |
KR20010001270A (ko) * | 1999-06-03 | 2001-01-05 | 복성해 | 혈관신생을 억제하는 새로운 이소쿠마린 유도체 |
WO2001026648A1 (fr) | 1999-10-13 | 2001-04-19 | Senju Pharmaceutical Co., Ltd. | Preparation d'adhesif a usage ophtalmique pour l'absorption par voie percutanee |
AU1735001A (en) * | 1999-12-10 | 2001-06-18 | Senju Pharmaceutical Co., Ltd. | Cyclodextrin-containing pharmaceutical composition |
JPWO2002034252A1 (ja) * | 2000-10-26 | 2004-03-04 | 千寿製薬株式会社 | ジペプチジルアルデヒド誘導体含有医薬組成物 |
WO2002048096A1 (fr) * | 2000-12-12 | 2002-06-20 | Senju Pharmaceutical Co., Ltd. | Derives d'hydrazone et utilisation de ceux-ci dans des medicaments |
NZ529098A (en) | 2001-06-06 | 2005-08-26 | Lilly Co Eli | Benzoylsulfonamides and sulfonylbenzamidines for use as antitumour agents |
US7115607B2 (en) * | 2001-07-25 | 2006-10-03 | Amgen Inc. | Substituted piperazinyl amides and methods of use |
WO2003078415A1 (fr) * | 2002-03-15 | 2003-09-25 | Senju Pharmaceutical Co., Ltd. | Derive de l'hemiacetal cyclique et son utilisation |
ATE473216T1 (de) | 2002-03-29 | 2010-07-15 | Senju Pharma Co | Hydroxymorpholinonderivat und dessen medizinische verwendung |
EP1354586A1 (en) * | 2002-04-20 | 2003-10-22 | Aventis Pharma Deutschland GmbH | The use of hydroxpyridone-derivatives in wound healing |
ATE448198T1 (de) * | 2002-07-22 | 2009-11-15 | Senju Pharma Co | Neue alpha-ketoamidderivate und deren verwendung |
GB0314262D0 (en) | 2003-06-19 | 2003-07-23 | Univ Nottingham Trent | Novel compounds and methods of using the same |
US7615556B2 (en) * | 2006-01-27 | 2009-11-10 | Bristol-Myers Squibb Company | Piperazinyl derivatives as modulators of chemokine receptor activity |
US8236798B2 (en) | 2009-05-07 | 2012-08-07 | Abbott Gmbh & Co. Kg | Carboxamide compounds and their use as calpain inhibitors |
EP2541716A1 (en) | 2010-02-25 | 2013-01-02 | Panasonic Corporation | Demand and supply control apparatus, demand and supply control method, and program |
CN103052382B (zh) | 2010-07-14 | 2014-10-22 | 千寿制药株式会社 | α-酮酰胺衍生物的固体分散体 |
GB201218084D0 (en) | 2012-10-09 | 2012-11-21 | Univ Aston | Novel compounds and methods for use in medicine |
GB201220474D0 (en) * | 2012-11-14 | 2012-12-26 | Sagetis Biotech Sl | Polypeptides |
US20210145930A1 (en) * | 2018-05-07 | 2021-05-20 | NeuroTheranostics, Inc. | Multiple layer article with interactive reinforcements linear ribbon fiber reinforcement for composite forms |
WO2022187491A1 (en) * | 2021-03-03 | 2022-09-09 | The Texas A& M University System | Inhibitors of cysteine proteases |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS50137951A (pt) | 1974-04-27 | 1975-11-01 | ||
JPS5754157A (en) | 1980-09-19 | 1982-03-31 | Nippon Kayaku Co Ltd | L-argininal derivative and its preparation |
PT84170B (pt) * | 1986-01-24 | 1989-03-30 | Sanofi Sa | Processo para a preparacao de derivados n alfa-substituidos das n alfa-aril-sulfonilaminoacil d-amidinofenil-alaninamidas |
JP2536754B2 (ja) * | 1987-05-08 | 1996-09-18 | 日本ケミファ株式会社 | ピペラジン誘導体 |
JPH0832698B2 (ja) * | 1987-05-08 | 1996-03-29 | 日本ケミファ株式会社 | ピペラジン誘導体 |
JP2701932B2 (ja) * | 1989-04-10 | 1998-01-21 | サントリー株式会社 | タンパク質分解酵素阻害剤 |
US5510531A (en) | 1989-04-10 | 1996-04-23 | Suntory Limited | Proteinase inhibitor |
EP0395309B1 (en) * | 1989-04-28 | 1995-12-27 | Takara Shuzo Co. Ltd. | Human calpastatin-like polypeptide |
JPH06506921A (ja) | 1991-02-22 | 1994-08-04 | ザ・デュポン・メルク・ファーマシュウティカル・カンパニー | 置換α−アミノアルデヒドおよび誘導体 |
EP0504938A3 (en) * | 1991-03-22 | 1993-04-14 | Suntory Limited | Prophylactic and therapeutic agent for bone diseases comprising di- or tripeptide derivative as active ingredient |
CA2071621C (en) * | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
JP2848232B2 (ja) | 1993-02-19 | 1999-01-20 | 武田薬品工業株式会社 | アルデヒド誘導体 |
US5607831A (en) | 1993-03-25 | 1997-03-04 | The United States Of America As Represented By The Department Of Health And Human Services | In vitro methods for assessing the susceptibility of HIV-1-infected individuals to cysteine protease-mediated activation-induced programmed cell death |
US5658885A (en) | 1993-04-27 | 1997-08-19 | The Dupont Merck Pharmaceutical Company | Amidino and guanidino substituted boronic acid inhibitors of trypsin-like enzymes |
JP3599287B2 (ja) * | 1993-04-28 | 2004-12-08 | 三菱化学株式会社 | スルホンアミド誘導体 |
EP0783489A1 (en) * | 1994-09-27 | 1997-07-16 | Takeda Chemical Industries, Ltd. | Aldehyde derivatives as upsteine protease inhibitors |
US5614649A (en) | 1994-11-14 | 1997-03-25 | Cephalon, Inc. | Multicatalytic protease inhibitors |
EP0731107A1 (en) * | 1995-02-13 | 1996-09-11 | Takeda Chemical Industries, Ltd. | Production of aldehyde derivatives |
WO1996035711A1 (en) | 1995-05-10 | 1996-11-14 | Chiroscience Limited | Peptide compounds which inhibit metalloproteinase and tnf liberation, and their therapeutic use |
WO1997003060A1 (fr) * | 1995-07-13 | 1997-01-30 | Senju Pharmaceutical Co., Ltd. | Derives de la piperazine et leurs utilisations |
WO1997021690A1 (en) | 1995-11-28 | 1997-06-19 | Cephalon, Inc. | D-amino acid derived inhibitors of cysteine and serine proteases |
-
1996
- 1996-10-23 AT AT96116994T patent/ATE230275T1/de not_active IP Right Cessation
- 1996-10-23 DE DE69625575T patent/DE69625575T2/de not_active Expired - Lifetime
- 1996-10-23 DE DE69628050T patent/DE69628050T2/de not_active Expired - Lifetime
- 1996-10-23 AT AT99106760T patent/ATE239698T1/de not_active IP Right Cessation
- 1996-10-23 ES ES99102501T patent/ES2190139T3/es not_active Expired - Lifetime
- 1996-10-23 ES ES99106760T patent/ES2193615T3/es not_active Expired - Lifetime
- 1996-10-23 AT AT99102501T patent/ATE230389T1/de not_active IP Right Cessation
- 1996-10-23 EP EP99106760A patent/EP0927716B1/en not_active Expired - Lifetime
- 1996-10-23 EP EP96116994A patent/EP0771565B1/en not_active Expired - Lifetime
- 1996-10-23 DE DE69625622T patent/DE69625622T2/de not_active Expired - Lifetime
- 1996-10-24 PL PL96316669A patent/PL316669A1/xx unknown
- 1996-10-24 US US08/740,069 patent/US6057290A/en not_active Expired - Lifetime
- 1996-10-24 AU AU70384/96A patent/AU716495B2/en not_active Ceased
- 1996-10-24 MX MX9605156A patent/MX9605156A/es unknown
- 1996-10-24 CA CA2188817A patent/CA2188817C/en not_active Expired - Fee Related
- 1996-10-24 HU HU9602943A patent/HUP9602943A3/hu unknown
- 1996-10-24 NO NO964514A patent/NO964514L/no not_active Application Discontinuation
- 1996-10-25 BR BR9605267A patent/BR9605267A/pt not_active Application Discontinuation
- 1996-10-25 AR ARP960104906A patent/AR004694A1/es unknown
-
1999
- 1999-02-03 US US09/243,822 patent/US6551999B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69625575D1 (de) | 2003-02-06 |
ES2190139T3 (es) | 2003-07-16 |
ATE230275T1 (de) | 2003-01-15 |
AR004694A1 (es) | 1999-03-10 |
NO964514L (no) | 1997-04-28 |
DE69628050T2 (de) | 2004-04-01 |
CA2188817A1 (en) | 1997-04-26 |
DE69625575T2 (de) | 2003-09-25 |
EP0927716B1 (en) | 2003-05-07 |
DE69628050D1 (de) | 2003-06-12 |
DE69625622D1 (de) | 2003-02-06 |
HUP9602943A3 (en) | 1998-03-02 |
DE69625622T2 (de) | 2003-08-14 |
PL316669A1 (en) | 1997-04-28 |
US6551999B1 (en) | 2003-04-22 |
AU716495B2 (en) | 2000-02-24 |
US6057290A (en) | 2000-05-02 |
EP0771565A2 (en) | 1997-05-07 |
NO964514D0 (no) | 1996-10-24 |
MX9605156A (es) | 1998-05-31 |
ATE239698T1 (de) | 2003-05-15 |
ATE230389T1 (de) | 2003-01-15 |
CA2188817C (en) | 2010-01-26 |
EP0771565A3 (en) | 1998-11-04 |
AU7038496A (en) | 1997-05-01 |
EP0927716A1 (en) | 1999-07-07 |
ES2193615T3 (es) | 2003-11-01 |
EP0771565B1 (en) | 2003-01-02 |
HUP9602943A2 (en) | 1997-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA10 | Dismissal: dismissal - article 33 of industrial property law |