BR9504132A - Derivados de quinoxalina úteis em terapia - Google Patents
Derivados de quinoxalina úteis em terapiaInfo
- Publication number
- BR9504132A BR9504132A BR9504132A BR9504132A BR9504132A BR 9504132 A BR9504132 A BR 9504132A BR 9504132 A BR9504132 A BR 9504132A BR 9504132 A BR9504132 A BR 9504132A BR 9504132 A BR9504132 A BR 9504132A
- Authority
- BR
- Brazil
- Prior art keywords
- pct
- alkyl
- therapy
- derivatives useful
- quinoxaline derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Luminescent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9419318A GB9419318D0 (en) | 1994-09-24 | 1994-09-24 | Therapeutic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9504132A true BR9504132A (pt) | 1996-08-06 |
Family
ID=10761869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9504132A BR9504132A (pt) | 1994-09-24 | 1995-09-22 | Derivados de quinoxalina úteis em terapia |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5852016A (pt) |
| EP (1) | EP0783495B1 (pt) |
| JP (1) | JP2986920B2 (pt) |
| KR (1) | KR970706261A (pt) |
| CN (1) | CN1158610A (pt) |
| AT (1) | ATE213731T1 (pt) |
| AU (1) | AU688591B2 (pt) |
| BR (1) | BR9504132A (pt) |
| CA (1) | CA2200742C (pt) |
| CO (1) | CO4410336A1 (pt) |
| CZ (1) | CZ85797A3 (pt) |
| DE (1) | DE69525633T2 (pt) |
| DK (1) | DK0783495T3 (pt) |
| ES (1) | ES2171553T3 (pt) |
| FI (1) | FI971193A (pt) |
| GB (1) | GB9419318D0 (pt) |
| HU (1) | HUT77734A (pt) |
| IL (2) | IL115334A0 (pt) |
| MX (1) | MX9702259A (pt) |
| NO (1) | NO971261L (pt) |
| NZ (1) | NZ292922A (pt) |
| PE (1) | PE47596A1 (pt) |
| PL (1) | PL319405A1 (pt) |
| PT (1) | PT783495E (pt) |
| RU (1) | RU2135484C1 (pt) |
| TR (1) | TR199501158A2 (pt) |
| WO (1) | WO1996009295A1 (pt) |
| ZA (1) | ZA958023B (pt) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY132385A (en) * | 1995-08-31 | 2007-10-31 | Novartis Ag | 2,3-dioxo-1,2,3,4-tetrahydro-quinoxalinyl derivatives |
| PT784973E (pt) * | 1995-10-10 | 2002-06-28 | Pfizer | Derivados de quinoxalina para o tratamento de zumbido nos ouvidos |
| GB9604400D0 (en) | 1996-03-01 | 1996-05-01 | Pfizer Ltd | Compounds useful in therapy |
| WO1997046539A1 (en) | 1996-06-05 | 1997-12-11 | Warner-Lambert Company | Amide derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists |
| US5721256A (en) * | 1997-02-12 | 1998-02-24 | Gpi Nil Holdings, Inc. | Method of using neurotrophic sulfonamide compounds |
| US5922715A (en) * | 1997-02-18 | 1999-07-13 | American Home Products Corporation | 5-aminoalkoxy-1, 4-dihydroquinoxaline-2, 3-diones |
| JP2001511805A (ja) * | 1997-02-18 | 2001-08-14 | アメリカン・ホーム・プロダクツ・コーポレイション | ドパミン作動薬である５−アミノアルコキシ−１，４−ジヒドロキノキサリン−２，３−ジオン |
| TW526195B (en) | 1997-06-10 | 2003-04-01 | Novartis Ag | Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use |
| GB0310881D0 (en) * | 2003-05-12 | 2003-06-18 | Merck Sharp & Dohme | Pharmaceutical formulation |
| US10208000B2 (en) | 2015-12-16 | 2019-02-19 | University Of Kentucky Research Foundation | Eis inhibitors |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE572852C (de) * | 1931-03-08 | 1933-03-24 | Willy Messerschmitt Dipl Ing | Verfahren zur Herstellung von Flugzeugtragfluegeln mit trapezfoermigem Grundriss |
| DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
| DK715888D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Quinoxalinforbindelser, deres fremstilling og anvendelse |
| DE69132340T2 (de) * | 1990-11-06 | 2001-02-08 | Yamanouchi Pharma Co Ltd | Kondensiertes pyrazinderivat |
| DE4123106A1 (de) * | 1991-07-09 | 1993-01-14 | Schering Ag | Arzneimittel zur behandlung von entzugssymptomen |
| PT101004B (pt) * | 1991-10-26 | 1999-10-29 | Schering Ag | Derivados da quinoxalina, processo para a sua preparacao e composicoes farmaceuticas que os contem |
| DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
| PT647137E (pt) * | 1992-06-22 | 2008-11-24 | Univ California | Antagonistas dos receptores da glicina e a sua utilização |
| IL109397A0 (en) * | 1993-04-28 | 1994-07-31 | Schering Ag | Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same |
| DE4439493A1 (de) * | 1994-10-25 | 1996-05-02 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| DE4439492A1 (de) * | 1994-10-25 | 1996-05-02 | Schering Ag | Neue Chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
| US5614508A (en) * | 1995-06-07 | 1997-03-25 | Warner-Lambert Company | Amino acid derivatives of substituted quinoxaline 2,3-dione derivatives as glutamate receptor antagonists |
-
1994
- 1994-09-24 GB GB9419318A patent/GB9419318D0/en active Pending
-
1995
- 1995-09-08 KR KR1019970701887A patent/KR970706261A/ko active IP Right Grant
- 1995-09-08 CA CA002200742A patent/CA2200742C/en not_active Expired - Fee Related
- 1995-09-08 CZ CZ97857A patent/CZ85797A3/cs unknown
- 1995-09-08 WO PCT/EP1995/003559 patent/WO1996009295A1/en active IP Right Grant
- 1995-09-08 AT AT95932021T patent/ATE213731T1/de not_active IP Right Cessation
- 1995-09-08 RU RU97107018A patent/RU2135484C1/ru active
- 1995-09-08 US US08/809,337 patent/US5852016A/en not_active Expired - Fee Related
- 1995-09-08 HU HU9800754A patent/HUT77734A/hu unknown
- 1995-09-08 AU AU35232/95A patent/AU688591B2/en not_active Ceased
- 1995-09-08 PT PT95932021T patent/PT783495E/pt unknown
- 1995-09-08 EP EP95932021A patent/EP0783495B1/en not_active Expired - Lifetime
- 1995-09-08 MX MX9702259A patent/MX9702259A/es not_active IP Right Cessation
- 1995-09-08 NZ NZ292922A patent/NZ292922A/en unknown
- 1995-09-08 JP JP8510561A patent/JP2986920B2/ja not_active Expired - Fee Related
- 1995-09-08 CN CN95195253A patent/CN1158610A/zh active Pending
- 1995-09-08 PL PL95319405A patent/PL319405A1/xx unknown
- 1995-09-08 DK DK95932021T patent/DK0783495T3/da active
- 1995-09-08 DE DE69525633T patent/DE69525633T2/de not_active Expired - Fee Related
- 1995-09-08 ES ES95932021T patent/ES2171553T3/es not_active Expired - Lifetime
- 1995-09-18 IL IL11533495A patent/IL115334A0/xx unknown
- 1995-09-20 PE PE1995279512A patent/PE47596A1/es not_active Application Discontinuation
- 1995-09-22 CO CO95043930A patent/CO4410336A1/es unknown
- 1995-09-22 ZA ZA958023A patent/ZA958023B/xx unknown
- 1995-09-22 BR BR9504132A patent/BR9504132A/pt not_active IP Right Cessation
- 1995-09-22 TR TR95/01158A patent/TR199501158A2/xx unknown
-
1997
- 1997-03-19 NO NO971261A patent/NO971261L/no unknown
- 1997-03-21 FI FI971193A patent/FI971193A/fi unknown
-
1998
- 1998-09-07 IL IL12610498A patent/IL126104A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PE47596A1 (es) | 1996-11-12 |
| US5852016A (en) | 1998-12-22 |
| CA2200742A1 (en) | 1996-03-28 |
| ATE213731T1 (de) | 2002-03-15 |
| KR970706261A (ko) | 1997-11-03 |
| FI971193A0 (fi) | 1997-03-21 |
| DK0783495T3 (da) | 2002-04-22 |
| FI971193A (fi) | 1997-05-21 |
| DE69525633T2 (de) | 2002-08-08 |
| MX9702259A (es) | 1997-06-28 |
| PL319405A1 (en) | 1997-08-04 |
| NO971261D0 (no) | 1997-03-19 |
| CO4410336A1 (es) | 1997-01-09 |
| IL126104A0 (en) | 1999-05-09 |
| JP2986920B2 (ja) | 1999-12-06 |
| GB9419318D0 (en) | 1994-11-09 |
| HUT77734A (hu) | 1998-07-28 |
| ES2171553T3 (es) | 2002-09-16 |
| AU688591B2 (en) | 1998-03-12 |
| WO1996009295A1 (en) | 1996-03-28 |
| EP0783495B1 (en) | 2002-02-27 |
| PT783495E (pt) | 2002-07-31 |
| TR199501158A2 (tr) | 1997-02-21 |
| JPH09511526A (ja) | 1997-11-18 |
| ZA958023B (en) | 1997-03-24 |
| DE69525633D1 (de) | 2002-04-04 |
| EP0783495A1 (en) | 1997-07-16 |
| NZ292922A (en) | 1998-07-28 |
| RU2135484C1 (ru) | 1999-08-27 |
| CA2200742C (en) | 2001-09-11 |
| CN1158610A (zh) | 1997-09-03 |
| IL115334A0 (en) | 1995-12-31 |
| CZ85797A3 (cs) | 1998-09-16 |
| NO971261L (no) | 1997-05-05 |
| AU3523295A (en) | 1996-04-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] | ||
| B24C | Patent annual fee: request for for restoration |
Free format text: REFERENTE 13A., E 14A. ANUIDADES. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AO DESPACHO 24.3 NA RPI 2050 DE 20/04/2010, E COMPROVAR O RECOLHIMENTO DA 15A,16A,17A E 18A ANUIDADES. |