BR9207071A - 3-Fenilureído-azepin-2-onas e-benzazepin-2-onas úteis como antagonistas de colecistoquinina - Google Patents

3-Fenilureído-azepin-2-onas e-benzazepin-2-onas úteis como antagonistas de colecistoquinina

Info

Publication number
BR9207071A
BR9207071A BR9207071A BR9207071A BR9207071A BR 9207071 A BR9207071 A BR 9207071A BR 9207071 A BR9207071 A BR 9207071A BR 9207071 A BR9207071 A BR 9207071A BR 9207071 A BR9207071 A BR 9207071A
Authority
BR
Brazil
Prior art keywords
ones
benzazepin
phenylureido
azepin
useful
Prior art date
Application number
BR9207071A
Other languages
English (en)
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR9207071A publication Critical patent/BR9207071A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9207071A 1992-01-27 1992-12-16 3-Fenilureído-azepin-2-onas e-benzazepin-2-onas úteis como antagonistas de colecistoquinina BR9207071A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27
PCT/US1992/010720 WO1993015059A1 (en) 1992-01-27 1992-12-16 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Publications (1)

Publication Number Publication Date
BR9207071A true BR9207071A (pt) 1995-12-05

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9207071A BR9207071A (pt) 1992-01-27 1992-12-16 3-Fenilureído-azepin-2-onas e-benzazepin-2-onas úteis como antagonistas de colecistoquinina

Country Status (19)

Country Link
EP (1) EP0625145A1 (pt)
JP (1) JPH07503465A (pt)
KR (1) KR950700257A (pt)
CN (1) CN1074903A (pt)
AU (1) AU3276193A (pt)
BR (1) BR9207071A (pt)
CA (1) CA2117367A1 (pt)
CZ (1) CZ391092A3 (pt)
FI (1) FI943513A0 (pt)
HU (1) HUT70496A (pt)
IL (1) IL104472A0 (pt)
MX (1) MX9300409A (pt)
NO (1) NO942775L (pt)
NZ (1) NZ245759A (pt)
RU (1) RU94038063A (pt)
TW (1) TW213901B (pt)
WO (1) WO1993015059A1 (pt)
YU (1) YU4393A (pt)
ZA (1) ZA93582B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
DK0711283T3 (da) * 1993-07-26 1999-11-22 Pfizer Tetrahydro-1H-benzazepinoner og hexahydroazepinoner som selektive cholecystokinin-B-receptorantagonister
ATE206402T1 (de) * 1993-11-22 2001-10-15 Merck & Co Inc 3-acylaminobenzazepine
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
MX9702507A (es) * 1994-10-04 1997-07-31 Pfizer Nuevos intermedios y procedimientos para preparar antagonistas cck.
IL115589A0 (en) 1994-10-14 1996-01-19 Glaxo Spa Use of cck-b antagonists in pharmaceutical compositions
DE10153348A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
TW213901B (pt) 1993-10-01
HU9402195D0 (en) 1994-09-28
FI943513A (fi) 1994-07-26
YU4393A (sr) 1996-01-09
IL104472A0 (en) 1993-05-13
RU94038063A (ru) 1996-05-27
EP0625145A1 (en) 1994-11-23
CA2117367A1 (en) 1993-08-05
NO942775D0 (no) 1994-07-26
KR950700257A (ko) 1995-01-16
HUT70496A (en) 1995-10-30
WO1993015059A1 (en) 1993-08-05
JPH07503465A (ja) 1995-04-13
CZ391092A3 (en) 1994-01-19
CN1074903A (zh) 1993-08-04
FI943513A0 (fi) 1994-07-26
NO942775L (no) 1994-09-20
ZA93582B (en) 1994-07-27
MX9300409A (es) 1993-07-01
AU3276193A (en) 1993-09-01
NZ245759A (en) 1997-06-24

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Legal Events

Date Code Title Description
EE Request for examination
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal
FC Decision: refusal
HIFC Refusal cancelled
B15K Others concerning applications: alteration of classification

Ipc: C07K 5/078 (2006.01), A61K 38/00 (2006.0