BR112022012514A2 - Formas de dosagem sólidas que contêm bactérias e vesículas extracelulares microbianas - Google Patents
Formas de dosagem sólidas que contêm bactérias e vesículas extracelulares microbianasInfo
- Publication number
- BR112022012514A2 BR112022012514A2 BR112022012514A BR112022012514A BR112022012514A2 BR 112022012514 A2 BR112022012514 A2 BR 112022012514A2 BR 112022012514 A BR112022012514 A BR 112022012514A BR 112022012514 A BR112022012514 A BR 112022012514A BR 112022012514 A2 BR112022012514 A2 BR 112022012514A2
- Authority
- BR
- Brazil
- Prior art keywords
- dosage forms
- solid dosage
- extracellular vesicles
- forms containing
- containing bacteria
- Prior art date
Links
- 239000007909 solid dosage form Substances 0.000 title abstract 4
- 241000894006 Bacteria Species 0.000 title abstract 3
- 230000000813 microbial effect Effects 0.000 title abstract 3
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2813—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/282—Organic compounds, e.g. fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4883—Capsule finishing, e.g. dyeing, aromatising, polishing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
FORMAS DE DOSAGEM SÓLIDAS QUE CONTÊM BACTÉRIAS E VESÍCULAS EXTRACELULARES MICROBIANAS. A presente invenção refere-se a formas de dosagem sólidas entericamente revestidas que contêm um agente farmacêutico que inclui bactérias e/ou vesículas extracelulares microbianas (mEVs). A invenção também se refere a métodos para tratamento com o uso de tais formas de dosagem sólidas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201962954153P | 2019-12-27 | 2019-12-27 | |
PCT/US2020/066828 WO2021133904A1 (en) | 2019-12-27 | 2020-12-23 | Solid dosage forms containing bacteria and microbial extracellular vesicles |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112022012514A2 true BR112022012514A2 (pt) | 2022-09-06 |
Family
ID=74626080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112022012514A BR112022012514A2 (pt) | 2019-12-27 | 2020-12-23 | Formas de dosagem sólidas que contêm bactérias e vesículas extracelulares microbianas |
Country Status (13)
Country | Link |
---|---|
US (1) | US20230355689A1 (pt) |
EP (1) | EP4081195A1 (pt) |
JP (1) | JP2023510158A (pt) |
KR (1) | KR20220128362A (pt) |
CN (1) | CN114945357A (pt) |
AR (1) | AR122353A1 (pt) |
AU (1) | AU2020413225A1 (pt) |
BR (1) | BR112022012514A2 (pt) |
CA (1) | CA3165418A1 (pt) |
CO (1) | CO2022010242A2 (pt) |
MX (1) | MX2022007943A (pt) |
TW (1) | TW202135783A (pt) |
WO (1) | WO2021133904A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021252861A1 (en) * | 2020-06-11 | 2021-12-16 | Evelo Biosciences, Inc. | Compositions and methods for treating diseases and disorders using megasphaera sp |
EP4185307A1 (en) * | 2020-07-21 | 2023-05-31 | Evelo Biosciences, Inc. | Veillonella parvula strain as an oral therapy for neuroinflammatory diseases |
WO2023049268A1 (en) * | 2021-09-24 | 2023-03-30 | Evelo Biosciences, Inc. | Solid dosage forms containing bacteria and microbial extracellular vesicles |
WO2023113541A1 (en) * | 2021-12-16 | 2023-06-22 | Enterobiome Inc. | Pharmaceutical composition for preventing or treating cancer or inflammatory disease |
CN115252651B (zh) * | 2022-06-08 | 2024-06-07 | 广州知易生物科技有限公司 | 嗜粘蛋白阿克曼菌在制备防治高血压的组合物中的应用和含有其的组合物 |
WO2024050289A1 (en) * | 2022-08-29 | 2024-03-07 | Eli Lilly And Company | Compositions for oral delivery |
CN116509900B (zh) * | 2022-12-01 | 2023-11-10 | 佛山科学技术学院 | 益生菌或其细胞外囊泡在制备防治胃溃疡产品中的应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4775536A (en) | 1986-02-24 | 1988-10-04 | Bristol-Myers Company | Enteric coated tablet and process for making |
US5292522A (en) | 1989-06-20 | 1994-03-08 | Rohm Gmbh | Aqueous film coating agent for solid medicaments |
US5047258A (en) | 1989-07-14 | 1991-09-10 | Sterling Drug Inc. | Aqueous spray-coating process |
US6623759B2 (en) | 1996-06-28 | 2003-09-23 | Astrazeneca Ab | Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof |
DE19631084A1 (de) | 1996-08-01 | 1998-02-05 | Basf Ag | Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut |
US6312728B1 (en) | 1998-07-07 | 2001-11-06 | Cascade Development, Inc. | Sustained release pharmaceutical preparation |
KR100501022B1 (ko) | 1998-07-28 | 2005-07-18 | 다나베 세이야꾸 가부시키가이샤 | 장내 적소 방출형 제제 |
DE19937361A1 (de) * | 1999-08-12 | 2001-02-22 | Merck Patent Gmbh | Orale Darreichungsform |
US20040028737A1 (en) | 2002-08-12 | 2004-02-12 | Kopran Research Laboratories Limited | Enteric coated stable oral pharmaceutical composition of acid unstable drug and process for preparing the same |
DE10260919A1 (de) | 2002-12-20 | 2004-07-01 | Röhm GmbH & Co. KG | Verfahren zur Herstellung von überzogenen Arzneiformen und Nahrungsergänzungsmitteln mit Konzentrationsgradienten im Überzug |
US20070065513A1 (en) | 2003-10-31 | 2007-03-22 | Avi Avramoff | Stable lansoprazole formulation |
US9149439B2 (en) | 2005-03-21 | 2015-10-06 | Sandoz Ag | Multi-particulate, modified-release composition |
DE102005032806A1 (de) | 2005-07-12 | 2007-01-18 | Röhm Gmbh | Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten |
CN101209247B (zh) * | 2006-12-27 | 2011-12-14 | 天津中新药业集团股份有限公司 | 一种结肠靶向制剂的制备方法 |
CN101757042A (zh) * | 2009-05-25 | 2010-06-30 | 北京诚创康韵医药科技有限公司 | 一种益生菌微丸制剂及其制备 |
US8906668B2 (en) * | 2012-11-23 | 2014-12-09 | Seres Health, Inc. | Synergistic bacterial compositions and methods of production and use thereof |
CN105142616B (zh) | 2013-03-01 | 2018-02-13 | Bpsi控股有限责任公司 | 含有硅酸钙的延迟释放薄膜包衣及其包被的底物 |
JP6464142B2 (ja) * | 2013-03-14 | 2019-02-06 | セラバイオーム,エルエルシー | プロバイオティクス生物及び/又は治療剤の標的化胃腸管デリバリー |
-
2020
- 2020-12-23 BR BR112022012514A patent/BR112022012514A2/pt not_active Application Discontinuation
- 2020-12-23 AU AU2020413225A patent/AU2020413225A1/en active Pending
- 2020-12-23 MX MX2022007943A patent/MX2022007943A/es unknown
- 2020-12-23 KR KR1020227025604A patent/KR20220128362A/ko unknown
- 2020-12-23 CN CN202080090020.6A patent/CN114945357A/zh active Pending
- 2020-12-23 EP EP20853582.3A patent/EP4081195A1/en active Pending
- 2020-12-23 US US17/789,427 patent/US20230355689A1/en active Pending
- 2020-12-23 JP JP2022539136A patent/JP2023510158A/ja active Pending
- 2020-12-23 AR ARP200103650A patent/AR122353A1/es unknown
- 2020-12-23 WO PCT/US2020/066828 patent/WO2021133904A1/en active Application Filing
- 2020-12-23 CA CA3165418A patent/CA3165418A1/en active Pending
- 2020-12-25 TW TW109146331A patent/TW202135783A/zh unknown
-
2022
- 2022-07-19 CO CONC2022/0010242A patent/CO2022010242A2/es unknown
Also Published As
Publication number | Publication date |
---|---|
TW202135783A (zh) | 2021-10-01 |
AU2020413225A1 (en) | 2022-06-23 |
CO2022010242A2 (es) | 2022-10-21 |
KR20220128362A (ko) | 2022-09-20 |
MX2022007943A (es) | 2022-07-27 |
WO2021133904A1 (en) | 2021-07-01 |
JP2023510158A (ja) | 2023-03-13 |
CN114945357A (zh) | 2022-08-26 |
EP4081195A1 (en) | 2022-11-02 |
AR122353A1 (es) | 2022-09-07 |
US20230355689A1 (en) | 2023-11-09 |
CA3165418A1 (en) | 2021-07-01 |
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Legal Events
Date | Code | Title | Description |
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B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |