BR112021018995A2 - Método para preparar monoidrato de l-glufosinato de amônio cristalino e enzimas d-aminoácido oxidase mutantes - Google Patents

Método para preparar monoidrato de l-glufosinato de amônio cristalino e enzimas d-aminoácido oxidase mutantes

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Publication number
BR112021018995A2
BR112021018995A2 BR112021018995A BR112021018995A BR112021018995A2 BR 112021018995 A2 BR112021018995 A2 BR 112021018995A2 BR 112021018995 A BR112021018995 A BR 112021018995A BR 112021018995 A BR112021018995 A BR 112021018995A BR 112021018995 A2 BR112021018995 A2 BR 112021018995A2
Authority
BR
Brazil
Prior art keywords
glufosinate
monohydrate
ammonium
mutant
amino acid
Prior art date
Application number
BR112021018995A
Other languages
English (en)
Inventor
Michael Green Brian
Richard Oberholzer Matthew
Nadejda Pavlova
Melissa Witek Rachel
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Publication of BR112021018995A2 publication Critical patent/BR112021018995A2/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y104/00—Oxidoreductases acting on the CH-NH2 group of donors (1.4)
    • C12Y104/03—Oxidoreductases acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12Y104/03003—D-Amino-acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

são divulgados métodos para a preparação de monoidrato de l-glufosinato de amônio cristalino. os métodos incluem formar uma mistura compreendendo água, um solvente orgânico miscível em água, hidróxido de amônio e um material de partida de glufosinato contendo l-glufosinato de amônio e d-glufosinato de amônio. o monoidrato de l-glufosinato de amônio é cristalizado e separado da mistura, proporcionando a forma b de monoidrato de l-glufosinato de amônio. também são descritas composições e métodos empregando o monoidrato de l-glufosinato de amônio cristalino.
BR112021018995A 2019-04-16 2020-04-15 Método para preparar monoidrato de l-glufosinato de amônio cristalino e enzimas d-aminoácido oxidase mutantes BR112021018995A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962834675P 2019-04-16 2019-04-16
US202062978005P 2020-02-18 2020-02-18
PCT/US2020/028191 WO2020214631A1 (en) 2019-04-16 2020-04-15 Methods for producing crystalline l-glufosinate ammonium monohydrate

Publications (1)

Publication Number Publication Date
BR112021018995A2 true BR112021018995A2 (pt) 2021-11-30

Family

ID=70554206

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021018995A BR112021018995A2 (pt) 2019-04-16 2020-04-15 Método para preparar monoidrato de l-glufosinato de amônio cristalino e enzimas d-aminoácido oxidase mutantes

Country Status (10)

Country Link
US (1) US20220177499A1 (pt)
EP (1) EP3956336A1 (pt)
JP (1) JP2022529428A (pt)
KR (1) KR20210151952A (pt)
CN (1) CN113767107A (pt)
BR (1) BR112021018995A2 (pt)
CA (1) CA3133296A1 (pt)
IL (1) IL287204A (pt)
MX (1) MX2021012680A (pt)
WO (1) WO2020214631A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3148902A1 (en) 2017-07-18 2019-01-24 Basf Se Solid form of l-glufosinate hydrochloride
US11555046B2 (en) 2020-07-31 2023-01-17 Upl Ltd Crystalline form of L-glufosinate ammonium salt and process for production thereof
NZ797161A (en) * 2020-07-31 2023-12-22 Upl Ltd Crystalline form of l-glufosinate ammonium salt and process for production thereof
CN112760353A (zh) * 2021-03-16 2021-05-07 北京鑫佰利科技发展有限公司 一种l-草铵膦的生产方法
CN113234767B (zh) * 2021-05-13 2022-05-17 永农生物科学有限公司 制备不含结晶水的l-草铵膦铵盐的固体粉末的方法
CN113480573B (zh) * 2021-06-21 2023-08-15 上海七洲紫岳生物科技有限公司 L-草铵膦的晶型及其制备方法和应用

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CA2067060C (en) 1991-04-27 2002-11-26 Jean Kocur Liquid herbicidal compositions
JP3294647B2 (ja) 1991-12-13 2002-06-24 ヘキスト・アクチェンゲゼルシャフト Ｌ−ホスフィノトリシンおよびその誘導体の製造方法
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EP2060578B1 (en) 2006-09-04 2014-04-09 Meiji Seika Pharma Co., Ltd. Process for production of optically active aminophosphinylbutanoic acid
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CA3148902A1 (en) * 2017-07-18 2019-01-24 Basf Se Solid form of l-glufosinate hydrochloride

Also Published As

Publication number Publication date
EP3956336A1 (en) 2022-02-23
JP2022529428A (ja) 2022-06-22
IL287204A (en) 2021-12-01
CN113767107A (zh) 2021-12-07
MX2021012680A (es) 2021-11-12
KR20210151952A (ko) 2021-12-14
WO2020214631A1 (en) 2020-10-22
US20220177499A1 (en) 2022-06-09
CA3133296A1 (en) 2020-10-22

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