BR112018075462A2 - método para detectar a presença de material micobacteriano em uma amostra com o uso de um antígeno de manosil fosfocetídeo imobilizado, substrato sólido e biossensor - Google Patents

método para detectar a presença de material micobacteriano em uma amostra com o uso de um antígeno de manosil fosfocetídeo imobilizado, substrato sólido e biossensor

Info

Publication number
BR112018075462A2
BR112018075462A2 BR112018075462-5A BR112018075462A BR112018075462A2 BR 112018075462 A2 BR112018075462 A2 BR 112018075462A2 BR 112018075462 A BR112018075462 A BR 112018075462A BR 112018075462 A2 BR112018075462 A2 BR 112018075462A2
Authority
BR
Brazil
Prior art keywords
antigen
solid substrate
immobilized
biosensor
detecting
Prior art date
Application number
BR112018075462-5A
Other languages
English (en)
Inventor
Theodorus Castrop Johannes
Original Assignee
Kei International Limited
Tomorrows Ip Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from NL2016913A external-priority patent/NL2016913B1/en
Priority claimed from NL2016914A external-priority patent/NL2016914B1/en
Application filed by Kei International Limited, Tomorrows Ip Limited filed Critical Kei International Limited
Priority claimed from PCT/CN2017/087542 external-priority patent/WO2017211314A1/en
Publication of BR112018075462A2 publication Critical patent/BR112018075462A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/5695—Mycobacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C07H11/04—Phosphates; Phosphites; Polyphosphates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/20—Detection of antibodies in sample from host which are directed against antigens from microorganisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

a presente invenção refere-se a um substrato sólido que compreende um antígeno imobilizado no dito substrato cujo antígeno tem capacidade de se ligar a um anticorpo que é indicativo para a presença de material micobacteriano em um ser humano ou animal, e um método de detecção da presença de anticorpos contra material micobacteriano em uma amostra que aplica o dito substrato sólido que compreende o dito antígeno imobilizado. também é fornecido no presente documento um biossensor que compreende o dito substrato sólido.
BR112018075462-5A 2016-06-08 2017-06-08 método para detectar a presença de material micobacteriano em uma amostra com o uso de um antígeno de manosil fosfocetídeo imobilizado, substrato sólido e biossensor BR112018075462A2 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
NL2016913 2016-06-08
NL2016913A NL2016913B1 (en) 2016-06-08 2016-06-08 Solid substrate comprising antigens immobilised thereto and use thereof in a method for detecting the presence of mycobacterial material in a sample
NL2016914 2016-06-08
NL2016914A NL2016914B1 (en) 2016-06-08 2016-06-08 Solid substrate comprising antigens immobilised thereto and use thereof in a method for detecting the presence of mycobacterial material in a sample
NL2017204 2016-07-21
NL2017204A NL2017204B1 (en) 2016-06-08 2016-07-21 Solid substrate comprising antigens immobilised thereto, biosensor comprising said solid substrate and method for detecting the presence of mycobacterial material in a sample
PCT/CN2017/087542 WO2017211314A1 (en) 2016-06-08 2017-06-08 Method for detecting presence of mycobacterial material in sample using immobilised mannosyl phosphoketide antigen

Publications (1)

Publication Number Publication Date
BR112018075462A2 true BR112018075462A2 (pt) 2019-03-19

Family

ID=61023285

Family Applications (2)

Application Number Title Priority Date Filing Date
BR112018075462-5A BR112018075462A2 (pt) 2016-06-08 2017-06-08 método para detectar a presença de material micobacteriano em uma amostra com o uso de um antígeno de manosil fosfocetídeo imobilizado, substrato sólido e biossensor
BR112018075414-5A BR112018075414A2 (pt) 2016-06-08 2017-06-08 método para detectar a presença de material micobacteriano em uma amostra com o uso de pelo menos dois antígenos, substrato sólido e biossensor

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR112018075414-5A BR112018075414A2 (pt) 2016-06-08 2017-06-08 método para detectar a presença de material micobacteriano em uma amostra com o uso de pelo menos dois antígenos, substrato sólido e biossensor

Country Status (6)

Country Link
US (2) US11243204B2 (pt)
EP (2) EP3469366A4 (pt)
CN (2) CN109690313A (pt)
BR (2) BR112018075462A2 (pt)
NL (1) NL2017204B1 (pt)
RU (2) RU2018146528A (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL2017204B1 (en) 2016-06-08 2017-12-18 Kei International Ltd Solid substrate comprising antigens immobilised thereto, biosensor comprising said solid substrate and method for detecting the presence of mycobacterial material in a sample
NL2021443B1 (en) * 2018-08-08 2020-02-20 Kei International Ltd Synthetic antigens for tuberculosis detection
NL2022166B1 (en) * 2018-12-10 2020-07-02 Kei International Ltd Nitrocellulose sheet comprising immobilized immunoglobulins and lipid based antigens and use thereof
WO2022015917A1 (en) * 2020-07-15 2022-01-20 The Regents Of The University Of California Methods for detecting biomolecules of interest by biolayer interferometry

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Also Published As

Publication number Publication date
EP3469364A4 (en) 2019-11-13
NL2017204B1 (en) 2017-12-18
RU2018146447A (ru) 2020-07-10
CN109690313A (zh) 2019-04-26
EP3469366A1 (en) 2019-04-17
EP3469364A1 (en) 2019-04-17
EP3469366A4 (en) 2020-04-01
CN109791145A (zh) 2019-05-21
RU2018146528A (ru) 2020-07-09
US20190219574A1 (en) 2019-07-18
US11243204B2 (en) 2022-02-08
US20190302114A1 (en) 2019-10-03
RU2018146528A3 (pt) 2020-10-08
RU2018146447A3 (pt) 2020-10-08
BR112018075414A2 (pt) 2019-03-12

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Legal Events

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B350 Update of information on the portal [chapter 15.35 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2726 DE 04-04-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.