BR112017017719A2 - imunoensaio homogêneo com compensação para sinal antecedente - Google Patents
imunoensaio homogêneo com compensação para sinal antecedenteInfo
- Publication number
- BR112017017719A2 BR112017017719A2 BR112017017719A BR112017017719A BR112017017719A2 BR 112017017719 A2 BR112017017719 A2 BR 112017017719A2 BR 112017017719 A BR112017017719 A BR 112017017719A BR 112017017719 A BR112017017719 A BR 112017017719A BR 112017017719 A2 BR112017017719 A2 BR 112017017719A2
- Authority
- BR
- Brazil
- Prior art keywords
- signal compensation
- homogeneous immunoassay
- antecedent
- antecedent signal
- reagents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01049—Glucose-6-phosphate dehydrogenase (1.1.1.49)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6812—Assays for specific amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Abstract
imunoensaios homogêneos que permitem a compensação de sinais antecedentes inerentes em amostras e reagentes. o uso de imunoensaios homogêneos para a detecção da presença ou quantidade de arginina de dimetil simétrica (sdma) em amostras biológicas. reagentes e kits para conduzir os ensaios.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562118832P | 2015-02-20 | 2015-02-20 | |
PCT/US2016/018667 WO2016134251A1 (en) | 2015-02-20 | 2016-02-19 | Homogenous immunoassay with compensation for background signal |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112017017719A2 true BR112017017719A2 (pt) | 2018-04-10 |
Family
ID=56689082
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017017719A BR112017017719A2 (pt) | 2015-02-20 | 2016-02-19 | imunoensaio homogêneo com compensação para sinal antecedente |
Country Status (16)
Country | Link |
---|---|
US (3) | US10775365B2 (pt) |
EP (2) | EP4170346A1 (pt) |
JP (2) | JP6896637B2 (pt) |
KR (2) | KR20230018536A (pt) |
CN (2) | CN107250795B (pt) |
AR (1) | AR103745A1 (pt) |
AU (2) | AU2016219847B2 (pt) |
BR (1) | BR112017017719A2 (pt) |
CA (1) | CA2977062A1 (pt) |
ES (1) | ES2936294T3 (pt) |
FI (1) | FI3259593T3 (pt) |
HU (1) | HUE060884T2 (pt) |
MX (1) | MX2017010505A (pt) |
PL (1) | PL3259593T3 (pt) |
TW (1) | TWI721966B (pt) |
WO (1) | WO2016134251A1 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2977062A1 (en) | 2015-02-20 | 2016-08-25 | Idexx Laboratories, Inc. | Homogenous immunoassay with compensation for background signal |
TWI831753B (zh) * | 2017-10-19 | 2024-02-11 | 美商英代斯實驗公司 | 對稱性二甲基精胺酸之檢測 |
US10745492B1 (en) * | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
Family Cites Families (70)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3875011A (en) | 1972-11-06 | 1975-04-01 | Syva Co | Enzyme immunoassays with glucose-6-phosphate dehydrogenase |
US4341866A (en) * | 1980-06-02 | 1982-07-27 | Syva Company | Antienzyme termination in enzyme immunoassays |
DE3134787A1 (de) | 1981-09-02 | 1983-03-10 | Boehringer Mannheim Gmbh, 6800 Mannheim | Creatinin-antikoerper |
IT1199088B (it) * | 1984-03-09 | 1988-12-30 | Miles Italiana | Saggio di legame specifico mediante impiego di anti-g6pdh come marcante |
US4818703A (en) | 1985-10-23 | 1989-04-04 | Pizzolante John M | Stabilized alkaline picrate reagent for jaffe creatinine determination |
US6461825B1 (en) * | 1987-09-30 | 2002-10-08 | Sanofi (Societe Anonyme) | Immunometric assay kit and method applicable to whole cells |
EP0356160A3 (en) | 1988-08-24 | 1991-09-11 | The Board Of Trustees Of The Leland Stanford Junior University | Capillary device |
EP0399127A1 (en) * | 1989-05-23 | 1990-11-28 | Pharmacia ENI Diagnostics Inc. | Homogeneous immunochemical method for determining haptens by means of ion selective electrodes |
US5726010A (en) | 1991-07-31 | 1998-03-10 | Idexx Laboratories, Inc. | Reversible flow chromatographic binding assay |
US6455288B1 (en) | 1993-04-08 | 2002-09-24 | Dade Behring Marburg Gmbh | Homogeneous immunoassays using mutant glucose-6-phosphate dehydrogenases |
US5972703A (en) * | 1994-08-12 | 1999-10-26 | The Regents Of The University Of Michigan | Bone precursor cells: compositions and methods |
US5804452A (en) | 1995-04-27 | 1998-09-08 | Quidel Corporation | One step urine creatinine assays |
AU7269098A (en) | 1997-05-01 | 1998-11-24 | Cooke Pharma, Inc. | Cardiovascular disease risk assessment |
US6736957B1 (en) | 1997-10-16 | 2004-05-18 | Abbott Laboratories | Biosensor electrode mediators for regeneration of cofactors and process for using |
US6358699B1 (en) | 1999-02-05 | 2002-03-19 | Cooke Pharma | Assay for asymmetrical NG, NG dimethyl-l-arginine |
WO2001046221A1 (en) | 1999-12-22 | 2001-06-28 | The Research Foundation Of State University Of New York | Protein methylarginine-specific antibodies |
JP2004502948A (ja) | 2000-07-06 | 2004-01-29 | ファル ダイアグノスティクス | アルギニン化合物の検出のための方法及びキット |
EP1301790B1 (en) | 2000-07-12 | 2008-04-09 | Naser, Werner, Dr. | Direct assessment of analyte to reference molecule ratios |
DE10040904A1 (de) | 2000-08-18 | 2002-02-28 | Boeger Rainer H | Verfahren und Mittel zum Nachweis einer Wahrscheinlichkeit zukünftigen Fortschreitens von Gefässerkrankungen |
US6601006B2 (en) * | 2000-12-22 | 2003-07-29 | Idexx Laboratories, Inc. | Methods for the calibration of analyte assays |
US7241856B2 (en) | 2003-06-02 | 2007-07-10 | Pentron Clinical Technologies Llc | Dental resins, dental composite materials, and method of manufacture thereof |
FR2824825B1 (fr) * | 2001-05-15 | 2005-05-06 | Servier Lab | Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
JP4214271B2 (ja) | 2002-10-15 | 2009-01-28 | アークレイ株式会社 | クレアチニン測定用試験片 |
US7501053B2 (en) | 2002-10-23 | 2009-03-10 | Abbott Laboratories | Biosensor having improved hematocrit and oxygen biases |
WO2004046314A2 (en) | 2002-11-15 | 2004-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for detecting asymmetric dimethylarginine in a biological sample |
US20050148029A1 (en) | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
US6991911B2 (en) | 2003-12-15 | 2006-01-31 | Dade Behring Inc. | Assay for entactogens |
US7813880B2 (en) | 2004-03-25 | 2010-10-12 | University Of Maryland, Baltimore | Apparatus and method for providing optimal concentrations for medication infusions |
JP4980884B2 (ja) | 2004-03-30 | 2012-07-18 | ジーイー・ヘルスケア・バイオサイエンス・コーポレイション | 側方流動方式、材料、及び方法 |
US7220842B2 (en) | 2004-04-05 | 2007-05-22 | Dade Behring Inc. | Immunoassays for buprenorphine and norbuprenorphine |
US20060046273A1 (en) * | 2004-08-27 | 2006-03-02 | Lin-Zhi International Inc. | Homogeneous enzyme immunoassay for oral fluid |
ES2332218T3 (es) | 2004-11-04 | 2010-01-29 | Germediq Forschungs- Und Entwicklungsgesellschaft Mbh | Metodo para la determinacion de arginina, argininas metiladas y sus derivados. |
CA2495138C (en) * | 2005-01-20 | 2012-10-23 | Alison Jane Basile | Multiplexed analysis for determining a serodiagnosis of viral infection |
WO2006078813A2 (en) | 2005-01-21 | 2006-07-27 | Biosite Incorporated | Arginine analogs, and methods for their synthesis and use |
US7723127B2 (en) | 2005-03-03 | 2010-05-25 | Novx Systems Inc. | Immunoassay with extended dynamic range |
DE112006000731T5 (de) * | 2005-03-30 | 2008-06-26 | Ucl Biomedica P.L.C. | Assay zur Messung von asymmetrischem Methylarginin in einer biologischen Probe |
EP1877101B1 (en) | 2005-04-28 | 2016-11-16 | Ventana Medical Systems, Inc. | Enzymes conjugated to antibodies via a peg heterobifuctional linker |
EP1946121A2 (en) | 2005-10-27 | 2008-07-23 | Yale University, Inc. | Urinary proteomic biomarker patterns in preeclampsia |
DE102005060057A1 (de) | 2005-12-15 | 2007-06-28 | Kellner, Karl-Heinz, Dr. | Sandwich-Immunoassay für kleine Haptenmoleküle |
JP2007176872A (ja) | 2005-12-28 | 2007-07-12 | Sentan Seimei Kagaku Kenkyusho:Kk | アシンメトリックジメチルアルギニンを認識する抗体及びその製造方法並びに翻訳後修飾アミノ酸含有タンパク質の検出方法 |
CA2644499A1 (en) * | 2006-03-02 | 2007-09-13 | Perkinelmer Las, Inc. | Methods for distinguishing isomers using mass spectrometry |
WO2008154457A1 (en) | 2007-06-08 | 2008-12-18 | Ark Diagnosties, Inc. | Topiramate immunoassays |
FR2919063B1 (fr) | 2007-07-19 | 2009-10-02 | Biomerieux Sa | Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal. |
US8628936B2 (en) | 2007-12-05 | 2014-01-14 | King's College London | Methods and compositions for multiplexed screening of disease |
ES2828097T3 (es) | 2008-08-07 | 2021-05-25 | Idexx Lab Inc | Métodos para detectar dimetilarginina simétrica |
EP2349335B1 (en) | 2008-10-24 | 2013-08-07 | ARK Diagnostics, Inc. | Levetiracetam immunoassays |
AU2009347448B2 (en) | 2009-06-02 | 2015-07-02 | Biocrates Life Sciences Ag | New biomarkers for assessing kidney diseases |
CN101587118B (zh) | 2009-07-03 | 2012-09-12 | 长春迪瑞医疗科技股份有限公司 | 肌酐尿液分析试纸及制备方法 |
CN101598727B (zh) | 2009-07-09 | 2012-10-10 | 上海科华生物工程股份有限公司 | 定量测定人体血液尿素含量的干化学试纸 |
CN101865911A (zh) | 2010-03-16 | 2010-10-20 | 苏州市玮琪生物科技有限公司 | 一种尿肌酐定量检测卡 |
US8329424B2 (en) * | 2010-06-25 | 2012-12-11 | Siemens Healthcare Diagnostics | Reduction in false results in assay measurements |
DE102011055265A1 (de) | 2010-11-17 | 2012-05-24 | Karl-Heinz Kellner | Automatenfähiger Immunoassay für biogene Amine |
JP2012112785A (ja) | 2010-11-24 | 2012-06-14 | Tohoku Univ | 透析膜の評価方法 |
CN102154444B (zh) * | 2010-12-30 | 2013-09-25 | 北京九强生物技术股份有限公司 | 测定不对称二甲基精氨酸浓度的方法及诊断试剂盒 |
US8394647B2 (en) | 2011-02-17 | 2013-03-12 | Siemens Healthcare Diagnostics Inc. | Reducing non-covalently bound polysaccharide on supports |
CN102628868B (zh) | 2011-12-30 | 2014-09-17 | 北京九强生物技术股份有限公司 | 检测非对称二甲基精氨酸含量的胶乳增强免疫比浊法试剂盒 |
US9933428B2 (en) | 2012-01-10 | 2018-04-03 | Idexx Laboratories, Inc. | Immunoassay test slide |
WO2013124478A1 (en) * | 2012-02-24 | 2013-08-29 | Universität des Saarlandes | Symmetric dimethylarginine (sdma) modifies high density lipoprotein (hdl) to induce endothelial dysfunction |
US9074482B2 (en) * | 2012-04-24 | 2015-07-07 | United Technologies Corporation | Airfoil support method and apparatus |
US20140038203A1 (en) | 2012-07-09 | 2014-02-06 | Musc Foundation For Research Development | Methods for detecting or predicting kidney disease |
JP6131415B2 (ja) * | 2012-08-21 | 2017-05-24 | ヤンセン ファーマシューティカ エヌ.ベー. | イムノアッセイに使用するためのクエチアピンのハプテン |
EP2945942B1 (en) | 2013-01-18 | 2018-05-09 | ARK Diagnostics, Inc. | Voriconazole immunoassays |
WO2014126861A1 (en) | 2013-02-13 | 2014-08-21 | Ark Diagnostics, Inc. | Posaconazole immunoassays |
WO2015035155A1 (en) | 2013-09-05 | 2015-03-12 | Idexx Laboratories, Inc. | Methods for detecting renal disease |
ES2911268T3 (es) | 2013-12-17 | 2022-05-18 | Siemens Healthcare Diagnostics Inc | Preparación de conjugados de G6PDH mutante de múltiples haptenos y su uso para la detección de múltiples analitos |
CA2977062A1 (en) * | 2015-02-20 | 2016-08-25 | Idexx Laboratories, Inc. | Homogenous immunoassay with compensation for background signal |
CN105753969A (zh) * | 2016-04-06 | 2016-07-13 | 苏州博源医疗科技有限公司 | 非对称二甲基精氨酸免疫原、抗体和检测试剂及制备方法 |
TWI831753B (zh) * | 2017-10-19 | 2024-02-11 | 美商英代斯實驗公司 | 對稱性二甲基精胺酸之檢測 |
US10745492B1 (en) * | 2019-04-03 | 2020-08-18 | Ark Diagnostics, Inc. | Antibodies to symmetrically dimethylated arginine analytes and use thereof |
WO2023147417A2 (en) * | 2022-01-26 | 2023-08-03 | Idexx Laboratories, Inc. | Methods and compositions for differentiating progressive chronic kidney disease from stable chronic kidney disease |
-
2016
- 2016-02-19 CA CA2977062A patent/CA2977062A1/en active Pending
- 2016-02-19 KR KR1020237002450A patent/KR20230018536A/ko not_active Application Discontinuation
- 2016-02-19 WO PCT/US2016/018667 patent/WO2016134251A1/en active Application Filing
- 2016-02-19 ES ES16753142T patent/ES2936294T3/es active Active
- 2016-02-19 EP EP22199062.5A patent/EP4170346A1/en active Pending
- 2016-02-19 BR BR112017017719A patent/BR112017017719A2/pt unknown
- 2016-02-19 US US15/048,209 patent/US10775365B2/en active Active
- 2016-02-19 CN CN201680011235.8A patent/CN107250795B/zh active Active
- 2016-02-19 AU AU2016219847A patent/AU2016219847B2/en active Active
- 2016-02-19 FI FIEP16753142.5T patent/FI3259593T3/fi active
- 2016-02-19 KR KR1020177026206A patent/KR102492243B1/ko active IP Right Grant
- 2016-02-19 HU HUE16753142A patent/HUE060884T2/hu unknown
- 2016-02-19 MX MX2017010505A patent/MX2017010505A/es unknown
- 2016-02-19 CN CN202110789639.2A patent/CN113699125A/zh active Pending
- 2016-02-19 JP JP2017543909A patent/JP6896637B2/ja active Active
- 2016-02-19 PL PL16753142.5T patent/PL3259593T3/pl unknown
- 2016-02-19 EP EP16753142.5A patent/EP3259593B1/en active Active
- 2016-02-22 TW TW105105218A patent/TWI721966B/zh active
- 2016-02-23 AR ARP160100454A patent/AR103745A1/es unknown
-
2020
- 2020-07-08 US US16/924,081 patent/US11913942B2/en active Active
-
2021
- 2021-06-09 JP JP2021096446A patent/JP7459018B2/ja active Active
-
2022
- 2022-06-09 AU AU2022204015A patent/AU2022204015A1/en active Pending
-
2023
- 2023-12-20 US US18/390,909 patent/US20240248081A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
TWI721966B (zh) | 2021-03-21 |
PL3259593T3 (pl) | 2023-02-20 |
EP3259593A4 (en) | 2018-08-08 |
CN107250795A (zh) | 2017-10-13 |
JP6896637B2 (ja) | 2021-06-30 |
WO2016134251A1 (en) | 2016-08-25 |
KR20170117574A (ko) | 2017-10-23 |
EP4170346A1 (en) | 2023-04-26 |
US20160245801A1 (en) | 2016-08-25 |
US20240248081A1 (en) | 2024-07-25 |
US10775365B2 (en) | 2020-09-15 |
CN107250795B (zh) | 2021-07-30 |
EP3259593A1 (en) | 2017-12-27 |
FI3259593T3 (fi) | 2023-01-13 |
HUE060884T2 (hu) | 2023-04-28 |
EP3259593B1 (en) | 2022-10-05 |
JP2021156896A (ja) | 2021-10-07 |
AU2022204015A1 (en) | 2022-06-30 |
ES2936294T3 (es) | 2023-03-15 |
US11913942B2 (en) | 2024-02-27 |
AU2016219847B2 (en) | 2022-03-10 |
JP2018507408A (ja) | 2018-03-15 |
CN113699125A (zh) | 2021-11-26 |
KR102492243B1 (ko) | 2023-01-25 |
TW201643428A (zh) | 2016-12-16 |
US20210018496A1 (en) | 2021-01-21 |
KR20230018536A (ko) | 2023-02-07 |
AR103745A1 (es) | 2017-05-31 |
JP7459018B2 (ja) | 2024-04-01 |
MX2017010505A (es) | 2017-11-13 |
CA2977062A1 (en) | 2016-08-25 |
AU2016219847A1 (en) | 2017-08-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112016010106A2 (pt) | ensaios para igfbp7 com melhor desempenho em amostras biológicas | |
BR112016002685A2 (pt) | ensaios para timp2 que apresentam melhor desempenho em amostras biológicas | |
BRPI0618713B8 (pt) | cardiolipina modificada e seus usos | |
BR112013003391A2 (pt) | biomarcadores de câncer pancreático e usos dos mesmos | |
MX2020009021A (es) | Ensayos para detectar la presencia o la cantidad de un anticuerpo antifarmaco. | |
BR112017025051A2 (pt) | ensaio celular para detecção de homodímeros anti-cd3 | |
BR112017021256A2 (pt) | dispositivos e métodos para a análise de amostras | |
BR112015023239A2 (pt) | ensaio de combinação antígeno-anticorpo e métodos e composições para uso do mesmo | |
AU2018337650A1 (en) | High dynamic range assays in hazardous contaminant testing | |
BR112016023418A8 (pt) | método e kit para a quantificação de ovos de parasitas nas fezes | |
BR112014006432A2 (pt) | biomarcadores do câncer de pulmão e seus usos | |
MY198081A (en) | Urinalysis device and dry reagent for quantitative urinalysis | |
BR112012009291A2 (pt) | sistema de reconhecimento de subenchimento para um biossensor | |
BR112018005812A2 (pt) | ?método de imunoensaio para a detecção de um analito, kit de reagentes para detectar um analito por um imunoensaio e uso de um parceiro de ligação marcador-específico? | |
BR112016007037A2 (pt) | método para detectar câncer pancreático, anticorpo monoclonal e kit | |
BR112014020513A2 (pt) | Métodos e sistemas para amplificação de sinal de bioensaios | |
BR112017017719A2 (pt) | imunoensaio homogêneo com compensação para sinal antecedente | |
WO2015023503A3 (en) | Compositions and methods for multimodal analysis of cmet nucleic acids | |
WO2014151290A3 (en) | Assay for predictive biomarkers | |
BR112016017901A2 (pt) | ensaio inovador para detectar periostina humana | |
BR112018013381A2 (pt) | anticorpo especificamente ligante a antígenos derivados de miobacteria ou fragmento ligante a antígeno do mesmo | |
MY184286A (en) | Immunochromatographic device reduced in background noise and method for reducing background noise | |
GB201119585D0 (en) | Assay | |
GB2572102A (en) | A method, a kit and application thereof | |
WO2014126487A3 (en) | Diagnosis and detection of dengue virus infection using chicken egg antibodies |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] |