BR112015026122A2 - métodos para usar interleucina-10 para tratar doenças e desordens - Google Patents
métodos para usar interleucina-10 para tratar doenças e desordensInfo
- Publication number
- BR112015026122A2 BR112015026122A2 BR112015026122A BR112015026122A BR112015026122A2 BR 112015026122 A2 BR112015026122 A2 BR 112015026122A2 BR 112015026122 A BR112015026122 A BR 112015026122A BR 112015026122 A BR112015026122 A BR 112015026122A BR 112015026122 A2 BR112015026122 A2 BR 112015026122A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- interleukin
- disorders
- treat diseases
- administration
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5428—IL-10
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Transplantation (AREA)
Abstract
abstract: methods of using interleukin-10 for treating diseases and disorders methods of treating subjects having a disease or disorder responsive to il-10, including methods of administration and dosing regimens associated therewith, are provided. _______________________________________________________________________ resumo métodos para usar interleucina-10 para tratar doenças e desordens métodos para tratar sujeitos tendo uma doença ou desordem responsiva a il-10, incluindo métodos de administração e regimes de dosagem associados aos mesmos, são providos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361813563P | 2013-04-18 | 2013-04-18 | |
PCT/US2014/034247 WO2014172392A1 (en) | 2013-04-18 | 2014-04-15 | Methods of using interleukin-10 for treating diseases and disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015026122A2 true BR112015026122A2 (pt) | 2017-07-25 |
BR112015026122A8 BR112015026122A8 (pt) | 2020-01-21 |
Family
ID=51731807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015026122A BR112015026122A8 (pt) | 2013-04-18 | 2014-04-15 | agente de polietileno glicol-il-10 (peg-il-10), seu uso, composição farmacêutica, contentor estéril e kit |
Country Status (11)
Country | Link |
---|---|
US (3) | US9943568B2 (pt) |
EP (1) | EP2986306A4 (pt) |
JP (2) | JP2016519108A (pt) |
CN (2) | CN105209054A (pt) |
AU (1) | AU2014254019B2 (pt) |
BR (1) | BR112015026122A8 (pt) |
CA (1) | CA2908198A1 (pt) |
HK (1) | HK1215681A1 (pt) |
MX (1) | MX2015014438A (pt) |
RU (1) | RU2679889C2 (pt) |
WO (1) | WO2014172392A1 (pt) |
Families Citing this family (20)
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JP5888980B2 (ja) * | 2008-12-17 | 2016-03-22 | メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. | モノ−およびジ−pegil10の製造および用途 |
CA2908198A1 (en) | 2013-04-18 | 2014-10-23 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
US9823255B2 (en) | 2013-06-17 | 2017-11-21 | Armo Biosciences, Inc. | Method for assessing protein identity and stability |
AU2014311432A1 (en) * | 2013-08-30 | 2016-03-03 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
MX2016005915A (es) | 2013-11-11 | 2016-12-16 | Armo Biosciences Inc | Metodos de uso de interleucina-10 para tratar enfermedades y trastornos. |
CN106573072A (zh) | 2014-06-02 | 2017-04-19 | 阿尔莫生物科技股份有限公司 | 降低血清胆固醇的方法 |
CN107001438A (zh) | 2014-10-14 | 2017-08-01 | 阿尔莫生物科技股份有限公司 | 白细胞介素‑15组合物及其用途 |
CN107106655A (zh) | 2014-10-22 | 2017-08-29 | 阿尔莫生物科技股份有限公司 | 使用白细胞介素‑10治疗疾病和病症的方法 |
US10618970B2 (en) | 2015-02-03 | 2020-04-14 | Armo Biosciences, Inc. | Method of treating cancer with IL-10 and antibodies that induce ADCC |
EP3302547A1 (en) | 2015-05-28 | 2018-04-11 | Armo Biosciences, Inc. | Pegylated interleukin-10 for use in treating cancer |
WO2016196211A1 (en) * | 2015-05-29 | 2016-12-08 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
WO2017035232A1 (en) * | 2015-08-25 | 2017-03-02 | Armo Biosciences, Inc. | Methods of using interleukin-10 for treating diseases and disorders |
KR20180100133A (ko) * | 2016-01-05 | 2018-09-07 | 아르모 바이오사이언시스 인코포레이티드 | 질환 및 장애를 치료하기 위한 인터류킨-10을 사용하는 방법 |
CN108697776A (zh) | 2016-01-11 | 2018-10-23 | 阿尔莫生物科技股份有限公司 | 在产生抗原特异性cd8+t细胞中的白介素-10及其使用方法 |
BR102019007044A2 (pt) | 2019-04-05 | 2021-12-28 | Universidade Federal de Uberlândia | Peptídeos sintéticos com afinidade ao receptor de interleucina-10, composição farmacêutica e uso dos mesmos como imunomuduladores no tratamento de doenças autoimunes, inflamatórias ou alérgicas |
CN110724204B (zh) * | 2019-11-18 | 2021-10-22 | 广东菲鹏制药股份有限公司 | Fc融合蛋白的纯化方法 |
CN115667290A (zh) | 2020-05-12 | 2023-01-31 | 再生元制药公司 | 新型il10激动剂及其使用方法 |
WO2023114958A1 (en) * | 2021-12-16 | 2023-06-22 | Xalud Therapeutics, Inc. | Dosing regimen for il-10 encoding expression construct |
WO2023137227A1 (en) * | 2022-01-14 | 2023-07-20 | Karma Biotechnologies | Multi-vesicular lipid nanoparticle tolerogenic vaccines for induction of systemic immune tolerance in vivo |
WO2024058196A1 (en) * | 2022-09-13 | 2024-03-21 | Okinawa Institute Of Science And Technology School Corporation | New synthetic drugs for treating alzheimer's disease |
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2014
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- 2014-04-15 AU AU2014254019A patent/AU2014254019B2/en active Active
- 2014-04-15 BR BR112015026122A patent/BR112015026122A8/pt not_active IP Right Cessation
- 2014-04-15 WO PCT/US2014/034247 patent/WO2014172392A1/en active Application Filing
- 2014-04-15 CN CN201480024021.5A patent/CN105209054A/zh active Pending
- 2014-04-15 US US14/779,929 patent/US9943568B2/en active Active
- 2014-04-15 EP EP14784959.0A patent/EP2986306A4/en not_active Withdrawn
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US10357545B2 (en) | 2019-07-23 |
RU2015149387A (ru) | 2017-05-19 |
US20190314456A1 (en) | 2019-10-17 |
US20160058838A1 (en) | 2016-03-03 |
BR112015026122A8 (pt) | 2020-01-21 |
MX2015014438A (es) | 2016-05-18 |
AU2014254019B2 (en) | 2018-09-27 |
JP2019123719A (ja) | 2019-07-25 |
EP2986306A1 (en) | 2016-02-24 |
WO2014172392A1 (en) | 2014-10-23 |
AU2014254019A1 (en) | 2015-10-29 |
CA2908198A1 (en) | 2014-10-23 |
CN106913865A (zh) | 2017-07-04 |
US9943568B2 (en) | 2018-04-17 |
HK1215681A1 (zh) | 2016-09-09 |
RU2679889C2 (ru) | 2019-02-14 |
JP2016519108A (ja) | 2016-06-30 |
CN105209054A (zh) | 2015-12-30 |
US20180250364A1 (en) | 2018-09-06 |
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