BR112015011693A2 - composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos - Google Patents

composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos

Info

Publication number
BR112015011693A2
BR112015011693A2 BR112015011693A BR112015011693A BR112015011693A2 BR 112015011693 A2 BR112015011693 A2 BR 112015011693A2 BR 112015011693 A BR112015011693 A BR 112015011693A BR 112015011693 A BR112015011693 A BR 112015011693A BR 112015011693 A2 BR112015011693 A2 BR 112015011693A2
Authority
BR
Brazil
Prior art keywords
nattokinase
bromelain
phlebotrombotic
prevention
treatment
Prior art date
Application number
BR112015011693A
Other languages
English (en)
Inventor
Di Pierro Francesco
Original Assignee
Gnosis Spa
Velleja Res S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gnosis Spa, Velleja Res S R L filed Critical Gnosis Spa
Publication of BR112015011693A2 publication Critical patent/BR112015011693A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/22—Cysteine endopeptidases (3.4.22)
    • C12Y304/22032—Stem bromelain (3.4.22.32)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)

Abstract

resumo patente de invenção: "composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos". a presente invenção refere-se às composições compreendendo bromelina e nattokinase como seus únicos ingredientes ativos.
BR112015011693A 2012-11-23 2013-11-06 composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos BR112015011693A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001997A ITMI20121997A1 (it) 2012-11-23 2012-11-23 Composizioni fibrinolitiche per la prevenzione e il trattamento degli stati flebotrombotici
PCT/EP2013/073160 WO2014079689A1 (en) 2012-11-23 2013-11-06 Fibrinolytic compositions comprising bromelain and nattokinase for the prevention and treatment of phlebothrombotic states

Publications (1)

Publication Number Publication Date
BR112015011693A2 true BR112015011693A2 (pt) 2017-07-11

Family

ID=47633139

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015011693A BR112015011693A2 (pt) 2012-11-23 2013-11-06 composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos

Country Status (25)

Country Link
US (1) US20150297685A1 (pt)
EP (1) EP2922567B1 (pt)
JP (1) JP6319592B2 (pt)
KR (1) KR20150100641A (pt)
CN (1) CN104955474B (pt)
AU (1) AU2013349898B2 (pt)
BR (1) BR112015011693A2 (pt)
CA (1) CA2892426A1 (pt)
CY (1) CY1119064T1 (pt)
DK (1) DK2922567T3 (pt)
EA (1) EA027753B1 (pt)
ES (1) ES2637847T3 (pt)
GE (1) GEP201706717B (pt)
HR (1) HRP20170987T1 (pt)
HU (1) HUE034096T2 (pt)
IL (1) IL238937A0 (pt)
IT (1) ITMI20121997A1 (pt)
LT (1) LT2922567T (pt)
MX (1) MX2015006454A (pt)
PH (1) PH12015501131B1 (pt)
PL (1) PL2922567T3 (pt)
PT (1) PT2922567T (pt)
SI (1) SI2922567T1 (pt)
WO (1) WO2014079689A1 (pt)
ZA (1) ZA201503604B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11065310B2 (en) 2016-05-27 2021-07-20 Nattocat, LLC Compositions and methods for thromboembolism dissolution
CN105944091A (zh) * 2016-06-24 2016-09-21 方捷 抗血栓的纳豆激酶组合物及其制备方法
IT201600109433A1 (it) * 2016-10-28 2018-04-28 Difass Int S R L Composizioni gastroresistenti comprendenti bromelina associata a un estratto secco di ananas comosus (l.)
WO2020214033A1 (en) * 2019-04-17 2020-10-22 Erasmus University Medical Center Rotterdam Papain-like cysteine peptidase medicaments and uses thereof
JP2021017423A (ja) 2019-07-23 2021-02-15 株式会社Ｓｃｒｅｅｎホールディングス 灌流液および灌流方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005526719A (ja) * 2002-02-15 2005-09-08 ディーエスエム アイピー アセッツ ビー．ブイ． 血管新生関連病状の治療および予防のための、リコペンを含む組成物
JP2005220025A (ja) * 2004-02-03 2005-08-18 Kenko Tsusho Kk 経口摂取組成物
RU2318466C1 (ru) 2006-06-23 2008-03-10 Давид Георгиевич Кочиев Лазерная установка для абляции тканей и литотрипсии
WO2008021987A2 (en) * 2006-08-10 2008-02-21 Jon Barron Proteolytic enzyme formulations
AT504159A1 (de) * 2006-08-16 2008-03-15 Marlyn Nutraceuticals Inc Verwendung von proteasen
WO2008146178A2 (en) * 2007-05-30 2008-12-04 Wockhardt Research Centre A novel tablet dosage form
AT506095A1 (de) * 2007-12-03 2009-06-15 Volopharm Gmbh Verwendung von proteasen
EP3037102A1 (en) * 2009-11-23 2016-06-29 Stephen F. Olmstead Compositions and methods comprising serratia peptidase for inhibition and treatment of biofilms related to certain conditions

Also Published As

Publication number Publication date
PH12015501131A1 (en) 2015-08-03
EP2922567B1 (en) 2017-05-24
HUE034096T2 (en) 2018-01-29
SI2922567T1 (sl) 2017-07-31
HRP20170987T1 (hr) 2017-09-22
JP6319592B2 (ja) 2018-05-09
PT2922567T (pt) 2017-08-28
ES2637847T3 (es) 2017-10-17
PH12015501131B1 (en) 2015-08-03
AU2013349898A1 (en) 2015-06-11
CN104955474A (zh) 2015-09-30
KR20150100641A (ko) 2015-09-02
LT2922567T (lt) 2017-07-25
MX2015006454A (es) 2015-12-03
CA2892426A1 (en) 2014-05-30
EA201590796A1 (ru) 2015-09-30
CN104955474B (zh) 2017-09-19
JP2016504287A (ja) 2016-02-12
DK2922567T3 (en) 2017-07-24
PL2922567T3 (pl) 2017-10-31
EA027753B1 (ru) 2017-08-31
ITMI20121997A1 (it) 2014-05-24
ZA201503604B (en) 2016-08-31
CY1119064T1 (el) 2018-01-10
US20150297685A1 (en) 2015-10-22
GEP201706717B (en) 2017-08-10
WO2014079689A1 (en) 2014-05-30
IL238937A0 (en) 2015-07-30
EP2922567A1 (en) 2015-09-30
AU2013349898B2 (en) 2018-05-10

Similar Documents

Publication Publication Date Title
AR081681A1 (es) METODOS Y COMPOSICIONES PARA LA ADMINISTRACION INTRATECAL DE b-GALACTOCEREBROSIDASA
BR112015021999A2 (pt) inibidores de indoleamina 2,3-dioxigenase (ido)
CR20130487A (es) 1,3-oxazinas como inhibidores de BACE1 y/o BACE2
BR112015010663A2 (pt) formas de dosagem de ruxolitinib de liberação sustentada
PH12014501967B1 (en) Benzodioxanes in combination with other actives for inhibiting leukotriene production
NZ630805A (en) Pharmaceutical combinations comprising a thionucleotide analog
CO6821938A2 (es) Un compuesto de guanidina o una sal del mismo para el tratamiento de enfermedades relacionadas con vap -1
MY185139A (en) Substituted imidazopyridazines
MY168413A (en) Amino-substituted imidazopyridazines
ECSP14033371A (es) Composiciones farmacéuticas y tratamiento de mastitis
BR112014015568A8 (pt) compostos carbamato de fenila para uso em prevenção ou tratamento de epilepsia
MX2013012661A (es) Compuestos de piridazina biciclicos como inhibidores pim.
BR112015011693A2 (pt) composições fibrinolíticas compreendendo bromelina e nattokinase para a prevenção e tratamento de estados flebotrombóticos
PH12014502623B1 (en) Difluoro-hexahydro-cyclopentaoxazinyls and difluoro-hexahydro-benzooxazinyls as bace1 inhibitors
BR112014024033A8 (pt) Formulação vesicular, método para o tratamento da rosácea e uso de um ou mais fosfo, sulfolipídios e surfactantes
MX2019012375A (es) Formulaciones del inhibidor del antigeno-1 asociado a la funcion de linfocitos (lfa-1).
MX2014011218A (es) Uso de agentes tensoactivos anfotericos para la prevencion y tratamiento de biopeliculas vaginales patogenas en infecciones vaginales.
IN2014CN04222A (pt)
GB201115977D0 (en) Neurodevelopmental disorders
BR112014015193A8 (pt) composição enriquecida com glicoproteína como um aditivo para alimento e/ou ração e/ou como um agente terapêutico
TN2014000091A1 (en) Amino-substituted imidazopyridazines
TR201200212A2 (tr) Risedronat içeren geliştirilmiş formülasyonlar.

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2539 DE 03-09-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.