BR112014016804A2 - composições, métodos de uso e métodos de tratamento - Google Patents

composições, métodos de uso e métodos de tratamento

Info

Publication number
BR112014016804A2
BR112014016804A2 BR112014016804A BR112014016804A BR112014016804A2 BR 112014016804 A2 BR112014016804 A2 BR 112014016804A2 BR 112014016804 A BR112014016804 A BR 112014016804A BR 112014016804 A BR112014016804 A BR 112014016804A BR 112014016804 A2 BR112014016804 A2 BR 112014016804A2
Authority
BR
Brazil
Prior art keywords
methods
treatment
compositions
beta
pharmaceutical compositions
Prior art date
Application number
BR112014016804A
Other languages
English (en)
Other versions
BR112014016804A8 (pt
Inventor
R Renslo Adam
nichols Derek
M W Lauterwasser Erica
Jaishankar Priyadarshini
Chen Yu
Original Assignee
Univ California
Univ South Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California, Univ South Florida filed Critical Univ California
Publication of BR112014016804A2 publication Critical patent/BR112014016804A2/pt
Publication of BR112014016804A8 publication Critical patent/BR112014016804A8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

resumo “composições, métodos de uso e métodos de tratamento” formas de realização da presente descrição, em um aspecto, referem-se a um inibidor de beta-lactamase, a composições farmacêuticas, incluindo um inibidor de beta-lactamase, os métodos de tratamento de um estado (por exemplo, infecção) ou doença, os métodos de tratamento utilizando as composições ou formulações farmacêuticas, e semelhantes.
BR112014016804A 2012-01-06 2013-01-04 composições, métodos de uso e métodos de tratamento BR112014016804A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261583679P 2012-01-06 2012-01-06
PCT/US2013/020212 WO2013103760A1 (en) 2012-01-06 2013-01-04 Compositions, methods of use, and methods of treatment

Publications (2)

Publication Number Publication Date
BR112014016804A2 true BR112014016804A2 (pt) 2017-06-13
BR112014016804A8 BR112014016804A8 (pt) 2017-07-04

Family

ID=48745416

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014016804A BR112014016804A8 (pt) 2012-01-06 2013-01-04 composições, métodos de uso e métodos de tratamento

Country Status (9)

Country Link
US (2) US9556131B2 (pt)
EP (1) EP2800568A4 (pt)
JP (1) JP2015506360A (pt)
CN (1) CN104159587A (pt)
AU (1) AU2013207510A1 (pt)
BR (1) BR112014016804A8 (pt)
CA (1) CA2860672A1 (pt)
MX (1) MX2014008278A (pt)
WO (1) WO2013103760A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015112441A1 (en) * 2014-01-22 2015-07-30 Merck Sharp & Dohme Corp. Metallo-beta-lactamase inhibitors
WO2016206101A1 (en) 2015-06-26 2016-12-29 Merck Sharp & Dohme Corp. Metallo-beta-lactamase inhibitors
WO2017152033A1 (en) * 2016-03-03 2017-09-08 University Of South Florida Compositions, methods of use, and methods of treatment
EP3740482A1 (en) * 2018-01-17 2020-11-25 Migal Galilee Research Institute Ltd. New methionine metabolic pathway inhibitors

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS591706B2 (ja) 1980-09-05 1984-01-13 わかもと製薬株式会社 アミノフエニルテトラゾ−ル誘導体及びその塩
US5049572A (en) 1987-04-06 1991-09-17 Riker Laboratories, Inc. Substituted di-t-butylphenols and anti-allergic use thereof
ZA882251B (en) * 1987-04-06 1989-11-29 Riker Laboratories Inc Substituted di-t-butylphenols
IT1232252B (it) 1989-02-22 1992-01-28 Rotta Research Lab Derivati della n fenil benzamide ad attivita' antiulcera ed antiallerica e procedimento per la loro preparazione
IT1256870B (it) 1992-02-13 1995-12-27 Rotta Research Lab Derivati bis-tetrazolici ad attivita' antiallergica e citoprotettiva
DE69631423T2 (de) * 1995-08-02 2004-12-02 Darwin Discovery Ltd., Slough Chinolone und deren therapeutische verwendung
DE19624155A1 (de) 1996-06-18 1998-01-08 Hoechst Ag Substituierte Benzoesäurederivate, Verfahren zu ihrer Herstellung und die Anwendung der Verbindungen zur Behandlung von Krankheiten
ES2178302T3 (es) * 1997-12-24 2002-12-16 Methylgene Inc Inhibidores de beta-lactamasa a base de fosf(on)ato de acilo.
GB0015095D0 (en) * 2000-06-20 2000-08-09 Celltech Chiroscience Ltd Chemical compounds
GB0218625D0 (en) * 2002-08-10 2002-09-18 Astex Technology Ltd Pharmaceutical compounds
PA8579701A1 (es) * 2002-08-23 2005-05-24 Pfizer Prod Inc Profarmaco inhibidor de beta-lactamasa
WO2005108370A1 (ja) 2004-04-16 2005-11-17 Ajinomoto Co., Inc. ベンゼン化合物
PE20110118A1 (es) 2005-10-04 2011-03-08 Aventis Pharma Inc Compuestos de pirimidina amida como inhibidores de pgds
MX2008012482A (es) * 2006-03-31 2008-10-10 Abbott Lab Compuestos de indazol.
AR063311A1 (es) * 2006-10-18 2009-01-21 Novartis Ag Compuestos organicos
US8003692B2 (en) * 2007-06-15 2011-08-23 Board Of Regents, The University Of Texas System Methods and compositions to inhibit edema factor and adenylyl cyclase
JP2011504468A (ja) * 2007-11-13 2011-02-10 プロテズ・ファーマシューティカルズ・インコーポレイテッド β−ラクタマーゼ阻害剤
RU2445314C9 (ru) * 2008-01-18 2013-04-10 Мерк Шарп Энд Домэ Корп. Ингибиторы бета-лактамаз
WO2011026107A1 (en) 2009-08-31 2011-03-03 University Of Notre Dame Du Lac Phthalanilate compounds and methods of use

Also Published As

Publication number Publication date
MX2014008278A (es) 2014-11-10
CA2860672A1 (en) 2013-07-11
CN104159587A (zh) 2014-11-19
EP2800568A4 (en) 2015-06-10
EP2800568A1 (en) 2014-11-12
BR112014016804A8 (pt) 2017-07-04
US10604493B2 (en) 2020-03-31
US9556131B2 (en) 2017-01-31
JP2015506360A (ja) 2015-03-02
US20140378516A1 (en) 2014-12-25
US20170088524A1 (en) 2017-03-30
WO2013103760A1 (en) 2013-07-11
AU2013207510A1 (en) 2014-07-31

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]