BR112013024288A2 - método para a produção de ácido graxo ou derivado de ácido graxo, organismo geneticamente modificado e produto - Google Patents
método para a produção de ácido graxo ou derivado de ácido graxo, organismo geneticamente modificado e produtoInfo
- Publication number
- BR112013024288A2 BR112013024288A2 BR112013024288A BR112013024288A BR112013024288A2 BR 112013024288 A2 BR112013024288 A2 BR 112013024288A2 BR 112013024288 A BR112013024288 A BR 112013024288A BR 112013024288 A BR112013024288 A BR 112013024288A BR 112013024288 A2 BR112013024288 A2 BR 112013024288A2
- Authority
- BR
- Brazil
- Prior art keywords
- fatty acid
- production
- product
- genetically modified
- modified organism
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/126—Acids containing more than four carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/14—Glutamic acid; Glutamine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y203/00—Acyltransferases (2.3)
- C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
- C12Y203/01041—Beta-ketoacyl-acyl-carrier-protein synthase I (2.3.1.41)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161466433P | 2011-03-22 | 2011-03-22 | |
| US201161466363P | 2011-03-22 | 2011-03-22 | |
| US201161539378P | 2011-09-26 | 2011-09-26 | |
| US201161539162P | 2011-09-26 | 2011-09-26 | |
| PCT/US2012/030209 WO2012129450A1 (en) | 2011-03-22 | 2012-03-22 | Microbial production of chemical products and related compositions, methods and systems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013024288A2 true BR112013024288A2 (pt) | 2016-08-16 |
Family
ID=46879750
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013024288A BR112013024288A2 (pt) | 2011-03-22 | 2012-03-22 | método para a produção de ácido graxo ou derivado de ácido graxo, organismo geneticamente modificado e produto |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140330032A1 (pt) |
| EP (2) | EP3385388A1 (pt) |
| CN (1) | CN103562398A (pt) |
| BR (1) | BR112013024288A2 (pt) |
| CA (1) | CA2868113A1 (pt) |
| MX (1) | MX2013010481A (pt) |
| WO (1) | WO2012129450A1 (pt) |
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| US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
| EP2602329A1 (de) * | 2011-12-05 | 2013-06-12 | Evonik Degussa GmbH | Biotechnologische Herstellung von 3-Hydroxyisobuttersäure |
| WO2013192183A1 (en) * | 2012-06-18 | 2013-12-27 | Braskem S/A Ap 09 | Modified microorganisms and methods of co-producing butadiene with 1-propanol and/or 1,2-propanediol |
| MX2015001780A (es) * | 2012-08-10 | 2015-09-28 | Opx Biotechnologies Inc | Microorganismos y métodos para la producción de ácidos grasos y productos derivados de ácidos grasos. |
| CA2891130A1 (en) | 2012-11-30 | 2014-06-05 | Novozymes, Inc. | 3-hydroxypropionic acid production by recombinant yeasts |
| WO2014145343A1 (en) * | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
| CA2905602A1 (en) | 2013-03-15 | 2014-09-18 | Sarah M. Hoyt | Flash evaporation for product purification and recovery |
| WO2014146026A1 (en) | 2013-03-15 | 2014-09-18 | Opx Biotechnologies, Inc. | Bioproduction of chemicals |
| US11408013B2 (en) | 2013-07-19 | 2022-08-09 | Cargill, Incorporated | Microorganisms and methods for the production of fatty acids and fatty acid derived products |
| CN106795483A (zh) * | 2013-07-19 | 2017-05-31 | 嘉吉公司 | 用于生产脂肪酸和脂肪酸衍生产物的微生物及方法 |
| DE102014201384A1 (de) * | 2014-01-27 | 2015-07-30 | Evonik Industries Ag | Verfahren umfassend eine Kultivierung unter niedriger Gelöstsauerstoffkonzentration |
| JP6730199B2 (ja) | 2014-06-11 | 2020-07-29 | デューク ユニバーシティ | 合成代謝弁を用いた迅速かつ動的なフラックス制御のための組成物及び方法 |
| WO2016012607A1 (en) * | 2014-07-25 | 2016-01-28 | Delphi Genetics | Improved host cell for producing proteins |
| EP2993228B1 (en) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Production of fatty acid esters |
| FR3030575A1 (fr) * | 2014-12-22 | 2016-06-24 | Inst Nat Des Sciences Appliquees De Toulouse | Procede de synthese d'acides gras |
| EP3320088A1 (en) * | 2015-07-08 | 2018-05-16 | Rheinisch-Westfälische Technische Hochschule Aachen (RWTH) | Extracellular production of designer hydroxyalkanoyloxy alkanoic acids with recombinant bacteria |
| CN108698983A (zh) * | 2016-02-19 | 2018-10-23 | 可持续能源联合有限责任公司 | 用于产生腈的***和方法 |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| WO2018144701A2 (en) | 2017-02-02 | 2018-08-09 | Cargill Incorporated | Genetically modified cells that produce c6-c10 fatty acid derivatives |
| US11078502B2 (en) | 2017-02-17 | 2021-08-03 | Hyasynth Biologicals Inc. | Method and cell line for production of polyketides in yeast |
| SG11201907685TA (en) | 2017-02-21 | 2019-09-27 | Univ Duke | Compositions and methods for robust dynamic metabolic control |
| CN108728471B (zh) * | 2017-04-14 | 2020-01-31 | 中国科学院微生物研究所 | 产3-羟基丙酸的重组菌及其制备方法与应用 |
| US11311027B2 (en) * | 2017-10-31 | 2022-04-26 | Inv Nylon Chemicals Americas, Llc | Nutritive compositions and methods related thereto |
| CN109722405B (zh) * | 2017-10-31 | 2023-06-23 | 创享(天津)生物科技发展有限公司 | 利用葡萄糖生产异丙基吡喃酮的重组大肠杆菌及用途 |
| CA3083563A1 (en) * | 2017-11-30 | 2019-06-06 | Toray Industries, Inc. | Gene-modified microorganism for producing 3-hydroxyadipic acid, .alpha.-hydromuconic acid, and/or adipic acid, and production method for said chemical products |
| US11732385B2 (en) | 2018-04-30 | 2023-08-22 | Alliance For Sustainable Energy, Llc | Emulsion polymerization of nitriles and other compounds |
| KR102187682B1 (ko) * | 2018-06-08 | 2020-12-07 | 한국과학기술원 | 타입 iii 폴리케타이드 합성 효소 기반 신규 말로닐-코에이 바이오센서 및 그 용도 |
| US11203744B2 (en) | 2018-06-21 | 2021-12-21 | Duke University | Compositions and methods for the production of pyruvic acid and related products using dynamic metabolic control |
| CN110438056B (zh) * | 2019-08-12 | 2021-05-28 | 江南大学 | 一株产正丁酸的大肠杆菌工程菌的构建及应用 |
| CN112410389B (zh) * | 2019-08-23 | 2023-07-18 | 中国科学院微生物研究所 | 支链α-酮酸脱氢酶复合体在制备丙二酸单酰辅酶A中的应用 |
| CN110713962B (zh) * | 2019-09-06 | 2022-06-21 | 南京农业大学 | 一株高产丙二酰辅酶a的基因工程菌及其构建方法和应用 |
| CN110564660B (zh) * | 2019-09-18 | 2023-03-21 | 苏州华赛生物工程技术有限公司 | 生产乳清酸的重组微生物及方法 |
| CN113249281B (zh) * | 2020-02-07 | 2022-11-11 | 中国科学院青岛生物能源与过程研究所 | 一种利用乙醇生产间苯三酚的重组菌及其构建方法与应用 |
| US20210381012A1 (en) * | 2020-06-03 | 2021-12-09 | School of Biotechnology, Rajiv Gandhi Proudyogiki Vishwavidyalay | Biopolymer film and method of preparing the same |
| CN113122563B (zh) * | 2021-04-22 | 2023-12-08 | 洛阳华荣生物技术有限公司 | 构建r-3-氨基丁酸生产菌的方法 |
| WO2023122649A1 (en) * | 2021-12-21 | 2023-06-29 | Mozhdehi Davoud | Temperature-responsive nano-biomaterials from genetically encoded farnesylated proteins |
| CN114774338B (zh) * | 2022-03-29 | 2023-08-08 | 北京航空航天大学 | 一种产丁酸的益生菌及其构建方法和应用 |
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| DE102006025821A1 (de) | 2006-06-02 | 2007-12-06 | Degussa Gmbh | Ein Enzym zur Herstellung von Mehylmalonatsemialdehyd oder Malonatsemialdehyd |
| MX2009002835A (es) * | 2006-09-18 | 2009-08-07 | Univ Arizona | Ácidos grasos e hidrocarburos de longitud de cadena media de algas. |
| MY154388A (en) * | 2007-06-06 | 2015-06-15 | Kao Corp | Transparent solid soap |
| WO2009006430A1 (en) * | 2007-06-29 | 2009-01-08 | The Regents Of The University Of California | Host cells and methods for producing fatty acid derived compounds |
| JP2009067775A (ja) | 2007-09-17 | 2009-04-02 | Rohm & Haas Co | ヒドロキシカルボン酸、またはその塩を、不飽和カルボン酸および／またはそのエステルに変換する方法 |
| BRPI0909839A2 (pt) | 2008-03-28 | 2017-06-13 | Univ California | produção de ácidos dicarboxílicos usando policetídeo sintases |
| DE102008002715A1 (de) | 2008-06-27 | 2009-12-31 | Evonik Röhm Gmbh | 2-Hydroxyisobuttersäure produzierende rekombinante Zelle |
| AU2009273953B2 (en) | 2008-07-23 | 2013-08-29 | Opx Biotechnologies, Inc | Methods, systems and compositions for increased microorganism tolerance to and production of 3-hydroxypropionic acid (3-HP) |
| BR112012006801A2 (pt) * | 2009-09-27 | 2018-04-10 | Opx Biotechnologies Inc | método para produção de ácido 3-hidroxipropiônico e outros produtos |
-
2012
- 2012-03-22 BR BR112013024288A patent/BR112013024288A2/pt not_active Application Discontinuation
- 2012-03-22 CN CN201280024996.9A patent/CN103562398A/zh active Pending
- 2012-03-22 EP EP18172179.6A patent/EP3385388A1/en not_active Withdrawn
- 2012-03-22 WO PCT/US2012/030209 patent/WO2012129450A1/en active Application Filing
- 2012-03-22 EP EP12759932.2A patent/EP2689020B1/en active Active
- 2012-03-22 MX MX2013010481A patent/MX2013010481A/es not_active Application Discontinuation
- 2012-03-22 CA CA2868113A patent/CA2868113A1/en not_active Abandoned
- 2012-03-22 US US14/006,014 patent/US20140330032A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20140330032A1 (en) | 2014-11-06 |
| EP2689020A4 (en) | 2014-12-31 |
| CN103562398A (zh) | 2014-02-05 |
| MX2013010481A (es) | 2014-03-05 |
| WO2012129450A1 (en) | 2012-09-27 |
| EP2689020A1 (en) | 2014-01-29 |
| EP3385388A1 (en) | 2018-10-10 |
| EP2689020B1 (en) | 2018-05-16 |
| CA2868113A1 (en) | 2012-09-27 |
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