BR112012015693A8 - métodos para diagnosticar uma doença renal em um canino, para tratar melhorar ou atrasar a progressão de uma doença renal, sonda de ácido nucléico, e, uso de uma sonda - Google Patents
métodos para diagnosticar uma doença renal em um canino, para tratar melhorar ou atrasar a progressão de uma doença renal, sonda de ácido nucléico, e, uso de uma sondaInfo
- Publication number
- BR112012015693A8 BR112012015693A8 BR112012015693A BR112012015693A BR112012015693A8 BR 112012015693 A8 BR112012015693 A8 BR 112012015693A8 BR 112012015693 A BR112012015693 A BR 112012015693A BR 112012015693 A BR112012015693 A BR 112012015693A BR 112012015693 A8 BR112012015693 A8 BR 112012015693A8
- Authority
- BR
- Brazil
- Prior art keywords
- kidney disease
- canine
- diagnosing
- methods
- probe
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
composições e métodos para diagnosticar e tratar doença renal em um canico a presente invenção fornece métodos para: diagnosticar, elaborar e monitorar um plano de tratamento para, e monitorar o estado de uma doença renal caracterizada por uma perda anormal da função renal, falha renal, taxa de filtração glomerular reduzido ou glomerulonefrite, em um canino, em que a doença renal é detectável usando pelo menos um biomarcador relevante isolado e medido de uma amostra de teste biológico tirada de tal canino. a invenção adicionalmente relaciona a composições, reagentes e kits para realizar os métodos específicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28977309P | 2009-12-23 | 2009-12-23 | |
PCT/US2010/062031 WO2011079280A2 (en) | 2009-12-23 | 2010-12-23 | Compositions and methods for diagnosing and treating kidney disorders in a canine |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112012015693A2 BR112012015693A2 (pt) | 2018-05-29 |
BR112012015693A8 true BR112012015693A8 (pt) | 2018-06-26 |
Family
ID=43927763
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012015693A BR112012015693A8 (pt) | 2009-12-23 | 2010-12-23 | métodos para diagnosticar uma doença renal em um canino, para tratar melhorar ou atrasar a progressão de uma doença renal, sonda de ácido nucléico, e, uso de uma sonda |
Country Status (10)
Country | Link |
---|---|
US (1) | US9476868B2 (pt) |
EP (1) | EP2517020B1 (pt) |
JP (2) | JP6199558B2 (pt) |
CN (1) | CN102713632B (pt) |
AU (1) | AU2010336392B2 (pt) |
BR (1) | BR112012015693A8 (pt) |
CA (1) | CA2785406A1 (pt) |
RU (1) | RU2546016C2 (pt) |
WO (1) | WO2011079280A2 (pt) |
ZA (2) | ZA201204531B (pt) |
Families Citing this family (11)
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EP3054301A1 (en) * | 2010-06-03 | 2016-08-10 | Idexx Laboratories, Inc. | Markers for renal disease |
US9255296B2 (en) | 2011-02-24 | 2016-02-09 | Hill's Pet Nutrition, Inc. | Compositions and methods for diagnosing and treating kidney disorders in a feline |
US20140309167A1 (en) * | 2011-11-09 | 2014-10-16 | Universita ; Degli Studi Bari | Combination of active ingredients for the treatment of acute kidney injury |
KR101609113B1 (ko) * | 2013-11-20 | 2016-04-05 | 영동제약 주식회사 | 신부전증 진단용 키트 및 그 방법 |
CN106164089B (zh) * | 2014-04-02 | 2020-11-03 | 日东电工株式会社 | 靶向分子及其用途 |
AR107786A1 (es) | 2016-03-02 | 2018-06-06 | Idexx Lab Inc | Métodos y composiciones para la detección y el diagnóstico de enfermedad renal y enfermedad periodontal |
WO2018094221A1 (en) * | 2016-11-18 | 2018-05-24 | Mayo Foundation For Medical Education And Research | Assessing and treating fibrillary glomerulonephritis |
JP2018096710A (ja) * | 2016-12-08 | 2018-06-21 | 国立大学法人金沢大学 | 血中タンパク質を測定することにより、ネフローゼ症候群の疾患活動性を判定する方法 |
CN109293763B (zh) * | 2018-10-26 | 2021-10-26 | 中国农业科学院特产研究所 | 水貂激活素b蛋白及其制备与应用 |
KR102167792B1 (ko) * | 2019-10-01 | 2020-10-19 | 대한민국 | 개의 고칼슘혈증 조기 예측 또는 진단용 조성물 |
CN111733140B (zh) * | 2020-04-04 | 2022-07-01 | 华中农业大学 | 一种抗犬基质金属蛋白酶的杂交瘤细胞株及其制备方法和一种单克隆抗体及其应用 |
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-
2010
- 2010-12-23 RU RU2012131367/15A patent/RU2546016C2/ru not_active IP Right Cessation
- 2010-12-23 US US13/519,048 patent/US9476868B2/en active Active
- 2010-12-23 CA CA2785406A patent/CA2785406A1/en not_active Abandoned
- 2010-12-23 AU AU2010336392A patent/AU2010336392B2/en active Active
- 2010-12-23 EP EP10807768.6A patent/EP2517020B1/en active Active
- 2010-12-23 WO PCT/US2010/062031 patent/WO2011079280A2/en active Application Filing
- 2010-12-23 JP JP2012546238A patent/JP6199558B2/ja active Active
- 2010-12-23 BR BR112012015693A patent/BR112012015693A8/pt not_active IP Right Cessation
- 2010-12-23 CN CN201080059274.8A patent/CN102713632B/zh not_active Expired - Fee Related
-
2012
- 2012-06-19 ZA ZA2012/04531A patent/ZA201204531B/en unknown
-
2014
- 2014-10-28 ZA ZA2014/07857A patent/ZA201407857B/en unknown
-
2016
- 2016-12-13 JP JP2016241219A patent/JP6174777B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP6199558B2 (ja) | 2017-09-20 |
US9476868B2 (en) | 2016-10-25 |
EP2517020B1 (en) | 2015-10-21 |
CN102713632A (zh) | 2012-10-03 |
JP2013515489A (ja) | 2013-05-09 |
RU2546016C2 (ru) | 2015-04-10 |
EP2517020A2 (en) | 2012-10-31 |
WO2011079280A3 (en) | 2011-11-17 |
ZA201407857B (en) | 2015-04-29 |
WO2011079280A2 (en) | 2011-06-30 |
RU2012131367A (ru) | 2014-01-27 |
US20120283129A1 (en) | 2012-11-08 |
JP6174777B2 (ja) | 2017-08-02 |
AU2010336392B2 (en) | 2014-01-23 |
JP2017079763A (ja) | 2017-05-18 |
ZA201204531B (en) | 2015-08-26 |
CA2785406A1 (en) | 2011-06-30 |
CN102713632B (zh) | 2015-10-07 |
BR112012015693A2 (pt) | 2018-05-29 |
AU2010336392A1 (en) | 2012-06-21 |
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