BR112012008128B8 - processos para a preparação de um composto da fórmula | e processo para a alquilação regiosseletiva de um composto da fórmula || - Google Patents

processos para a preparação de um composto da fórmula | e processo para a alquilação regiosseletiva de um composto da fórmula ||

Info

Publication number
BR112012008128B8
BR112012008128B8 BR112012008128A BR112012008128A BR112012008128B8 BR 112012008128 B8 BR112012008128 B8 BR 112012008128B8 BR 112012008128 A BR112012008128 A BR 112012008128A BR 112012008128 A BR112012008128 A BR 112012008128A BR 112012008128 B8 BR112012008128 B8 BR 112012008128B8
Authority
BR
Brazil
Prior art keywords
compound
formula
preparation
processes
regioselective alkylation
Prior art date
Application number
BR112012008128A
Other languages
English (en)
Other versions
BR112012008128A2 (pt
BR112012008128B1 (pt
Inventor
Thomas Ebert Jefferson
Wang Lihua
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Publication of BR112012008128A2 publication Critical patent/BR112012008128A2/pt
Publication of BR112012008128B1 publication Critical patent/BR112012008128B1/pt
Publication of BR112012008128B8 publication Critical patent/BR112012008128B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)

Abstract

processo para a preparação de um composto da fórmula i e processo para a alquilação regiosseletiva de um composto da fórmula ii a presente invenção refere-se a um processo para a preparação de um composto da fórmula i: em particular, em que um composto da fórmula ii: é reagido com um dialquilsulfato. r1 é c1-c4haloalquila; r2 é alquila opcionalmente substituída, arila opcionalmente substituída ou heteroarila opcionalmente substituída; e r3 é metila ou etila.
BR112012008128A 2009-07-31 2010-07-27 processos para a preparação de um composto da fórmula | e processo para a alquilação regiosseletiva de um composto da fórmula || BR112012008128B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23013409P 2009-07-31 2009-07-31
US61/230,134 2009-07-31
US36157010P 2010-07-06 2010-07-06
PCT/EP2010/060884 WO2011012620A2 (en) 2009-07-31 2010-07-27 Processes for the alkylation of pyrazoles

Publications (3)

Publication Number Publication Date
BR112012008128A2 BR112012008128A2 (pt) 2015-09-22
BR112012008128B1 BR112012008128B1 (pt) 2017-10-31
BR112012008128B8 true BR112012008128B8 (pt) 2019-07-16

Family

ID=42782270

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012008128A BR112012008128B8 (pt) 2009-07-31 2010-07-27 processos para a preparação de um composto da fórmula | e processo para a alquilação regiosseletiva de um composto da fórmula ||

Country Status (12)

Country Link
US (1) US8563747B2 (pt)
EP (1) EP2459538B1 (pt)
JP (1) JP5956334B2 (pt)
CN (1) CN102471279A (pt)
AR (1) AR077332A1 (pt)
BR (1) BR112012008128B8 (pt)
DK (1) DK2459538T3 (pt)
ES (1) ES2525489T3 (pt)
IL (1) IL217387A (pt)
MX (1) MX2012001067A (pt)
TW (1) TW201107296A (pt)
WO (1) WO2011012620A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2459539B1 (en) * 2009-07-28 2016-08-31 Syngenta Participations AG Processes relating to the alkylation of pyrazoles
BR112013004066A2 (pt) * 2010-08-10 2017-11-14 Syngenta Particpations Ag processo para a preparação de 3-haloalquilapirazóis.
JP5140776B1 (ja) * 2012-09-05 2013-02-13 タマ化学工業株式会社 １−置換−３−フルオロアルキルピラゾール−４−カルボン酸エステルの製造方法
ES2750353T3 (es) 2014-08-19 2020-03-25 Bayer Animal Health Gmbh Procedimiento de preparación de 5-fluoro-1H-pirazoles partiendo de hexafluoropropeno

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0759560B2 (ja) * 1987-10-19 1995-06-28 三井東圧化学株式会社 １，３−ジアルキルピラゾール−４−カルボン酸エステルの製造法
GB9405229D0 (en) 1994-03-17 1994-04-27 Rhone Poulenc Agriculture Compositions of matter
US5498624A (en) * 1995-05-03 1996-03-12 Monsanto Company Selected pyrazolyl derivatives
JP2000044541A (ja) * 1998-08-03 2000-02-15 Mitsui Chemicals Inc １，３−ジアルキルピラゾール−４−カルボン酸エステルの製造法
JP4568404B2 (ja) 2000-05-17 2010-10-27 三井化学アグロ株式会社 ピラゾールカルボン酸エステル誘導体の製造法
CA2477931C (en) 2002-03-05 2011-02-01 Josef Ehrenfreund O-cyclopropyl-carboxanilides and their use as fungicides
GB0224316D0 (en) 2002-10-18 2002-11-27 Syngenta Participations Ag Chemical compounds
WO2005123690A1 (de) 2004-06-18 2005-12-29 Basf Aktiengesellschaft 1-methyl-3-difluormethyl-pyrazol-4-carbonsäure-(ortho-phenyl)-anilide und ihre verwendung als fungizid
CN101044119B (zh) * 2004-10-21 2012-03-14 辛根塔参与股份公司 制备吡唑类化合物的方法
EP1854788B8 (en) * 2005-02-25 2012-12-26 Sagami Chemical Research Institute Method for producing 1-substituted-3-fluoroalkyl pyrazole-4-carboxylate
PL1940813T3 (pl) * 2005-10-25 2011-04-29 Syngenta Participations Ag Pochodne amidowe heterocykli użyteczne jako środki mikrobiobójcze
GB0526044D0 (en) * 2005-12-21 2006-02-01 Syngenta Ltd Novel herbicides
WO2008053044A2 (de) * 2006-11-03 2008-05-08 Basf Se Hetarylcarbonsäure-n-(biphen-2-yl)amid-verbindungen
UA97267C2 (ru) 2007-03-16 2012-01-25 Сингента Партисипейшнс Аг Кристаллические модификации с, i и моногидрат в форме а (9-изопропил-1,2,3,4-тетрагидро-1,4-метанонафталин-5-ил)-амида 3-дифторметил-1-метил-1н-пиразол-4-карбоновой кислоты, бактерицидная композиция, композиция для борьбы с болезнями полезных растений, способ борьбы с болезнями полезных растений и способ получения композиции
PT2155717E (pt) * 2007-05-11 2012-12-21 Lilly Co Eli 2-[4-(pirazol-4-ilalquil)piperazin-1-il]-3-fenil-pirazinas e -piridinas e 3-[4-(pirazol-4-ilalquil)piperazin-1-il]-2- fenil-piridinas como antagonistas do recetor 5-ht7
WO2008145257A1 (en) * 2007-05-31 2008-12-04 Syngenta Participations Ag Process for the production of pyrazoles
MX317270B (es) 2008-05-08 2014-01-20 Basf Se Procedimiento para la obtencion de arilcarboxamidas.
GB0812028D0 (en) 2008-07-01 2008-08-06 Syngenta Participations Ag Fungicidal compositions

Also Published As

Publication number Publication date
US8563747B2 (en) 2013-10-22
EP2459538A2 (en) 2012-06-06
MX2012001067A (es) 2012-03-16
WO2011012620A3 (en) 2011-06-09
DK2459538T3 (en) 2015-01-05
BR112012008128A2 (pt) 2015-09-22
EP2459538B1 (en) 2014-10-15
ES2525489T3 (es) 2014-12-23
TW201107296A (en) 2011-03-01
US20120130085A1 (en) 2012-05-24
BR112012008128B1 (pt) 2017-10-31
IL217387A (en) 2016-02-29
JP5956334B2 (ja) 2016-07-27
WO2011012620A2 (en) 2011-02-03
CN102471279A (zh) 2012-05-23
IL217387A0 (en) 2012-02-29
JP2013500945A (ja) 2013-01-10
AR077332A1 (es) 2011-08-17

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/07/2010, OBSERVADAS AS CONDICOES LEGAIS. (CO) REF. 2443 DE 31/10/2017 QUANTO AO ITEM (30) PRIORIDADE UNIONISTA.