BR0311952A - Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do snc - Google Patents
Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do sncInfo
- Publication number
- BR0311952A BR0311952A BR0311952-1A BR0311952A BR0311952A BR 0311952 A BR0311952 A BR 0311952A BR 0311952 A BR0311952 A BR 0311952A BR 0311952 A BR0311952 A BR 0311952A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetes
- type
- compounds useful
- new compounds
- treating obesity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201925A SE0201925D0 (sv) | 2002-06-20 | 2002-06-20 | New compounds |
SE0202181A SE0202181D0 (sv) | 2002-07-11 | 2002-07-11 | New compounds |
US40612002P | 2002-08-26 | 2002-08-26 | |
SE0202908A SE0202908D0 (sv) | 2002-10-01 | 2002-10-01 | New compounds |
US43401002P | 2002-12-17 | 2002-12-17 | |
SE0300357A SE0300357D0 (sv) | 2003-02-10 | 2003-02-10 | New compounds |
US46470103P | 2003-04-23 | 2003-04-23 | |
PCT/SE2003/001061 WO2004000828A1 (en) | 2002-06-20 | 2003-06-19 | New compounds useful for the treatment of obesity, type ii diabetes and cns disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0311952A true BR0311952A (pt) | 2005-04-19 |
Family
ID=30004107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0311952-1A BR0311952A (pt) | 2002-06-20 | 2003-06-19 | Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do snc |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1513828A1 (pt) |
CN (1) | CN1662521A (pt) |
AU (1) | AU2003243091A1 (pt) |
BR (1) | BR0311952A (pt) |
CA (1) | CA2486989A1 (pt) |
EA (2) | EA011581B1 (pt) |
IL (1) | IL165051A0 (pt) |
MX (1) | MXPA04012914A (pt) |
NO (1) | NO20050294L (pt) |
NZ (3) | NZ536600A (pt) |
RS (1) | RS111204A (pt) |
SG (1) | SG156524A1 (pt) |
WO (1) | WO2004000828A1 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4455064B2 (ja) | 2002-03-27 | 2010-04-21 | グラクソ グループ リミテッド | キノリン誘導体および5−ht6リガンドとしてのその使用 |
SE0301446D0 (sv) | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
ATE313532T1 (de) | 2003-07-22 | 2006-01-15 | Arena Pharm Inc | Diaryl- und arylheteroarylharnstoffderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich zur prophylaxe und behandlung von damit im zusammenhang stehenden erkrankungen eignen |
SE0302760D0 (sv) * | 2003-10-20 | 2003-10-20 | Biovitrum Ab | New compounds |
SE0303480D0 (sv) | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
KR20060127886A (ko) * | 2003-12-19 | 2006-12-13 | 바이오비트럼 에이비 | 5-ht6 수용체-관련 장애의 예방 및 치료에 사용될 수있는, 신규한 벤조퓨란 유도체 |
GB0407025D0 (en) * | 2004-03-29 | 2004-04-28 | Glaxo Group Ltd | Novel compounds |
US7745436B2 (en) * | 2004-04-13 | 2010-06-29 | Synta Pharmaceuticals Corporation | Disalt inhibitors of IL-12 production |
WO2006062481A1 (en) * | 2004-12-09 | 2006-06-15 | Biovitrum Ab | New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders . |
AR054044A1 (es) * | 2005-05-23 | 2007-05-30 | Astrazeneca Ab | Derivados de cromano y tetrahidronaftaleno como moduladores del receptor 5 - ht6; intermediarios en su preparacion; composiciones farmaceuticas que los contienen y su empelo en la fabricacion de medicamentos para el tratamiento de enfermedades del snc y de la obesidad. |
US7582767B2 (en) * | 2005-06-17 | 2009-09-01 | Biovitrum Ab (Publ.) | Substituted sulphonamide compound and uses thereof |
US20090221644A1 (en) * | 2005-06-30 | 2009-09-03 | Stuart Edward Bradley | Gpcr Agonists |
AU2006302179C1 (en) | 2005-10-07 | 2013-06-20 | Exelixis, Inc. | N- (3-amino-quinoxalin-2-yl) -sulfonamide derivatives and their use as phosphatidylinositol 3-kinase inhibitors |
BRPI0618206A2 (pt) | 2005-11-03 | 2011-08-23 | Hoffmann La Roche | arilsulfonil cromanos como inibidores de 5-ht6, bem como composição farmacêutica, uso e processo para produção dos mesmos |
AR058705A1 (es) | 2005-12-23 | 2008-02-20 | Astrazeneca Ab | Compuestos de bencimidazol como inhibidores del receptor vaniloide 1 (vr1) |
AU2007263084A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
CA2654822A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
EP2076489A1 (en) | 2006-06-20 | 2009-07-08 | F. Hoffmann-Roche AG | Arylsulfonamidyl tetralin derivatives and uses thereof |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
WO2009074607A1 (en) | 2007-12-12 | 2009-06-18 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
US7888662B2 (en) | 2008-06-20 | 2011-02-15 | Varian Semiconductor Equipment Associates, Inc. | Ion source cleaning method and apparatus |
WO2010062321A1 (en) | 2008-10-28 | 2010-06-03 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto |
AR082889A1 (es) * | 2011-05-09 | 2013-01-16 | Forma Therapeutics Inc | Compuestos y composiciones para la inhibicion de nampt |
WO2015090233A1 (en) | 2013-12-20 | 2015-06-25 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
WO2016201373A1 (en) | 2015-06-12 | 2016-12-15 | Axovant Sciences Ltd. | Diaryl and arylheteroaryl urea derivatives useful for the prophylaxis and treatment of rem sleep behavior disorder |
CN108472285A (zh) | 2015-07-15 | 2018-08-31 | 阿速万科学有限责任公司 | 用于预防和治疗与神经退行性疾病相关联的幻觉的二芳基和芳基杂芳基脲衍生物 |
US20190119236A1 (en) | 2016-02-23 | 2019-04-25 | Portola Pharmaceuticals, Inc. | Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9) |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB947606A (en) * | 1961-04-10 | 1964-01-22 | Ici Ltd | N-substituted piperazines |
US4808595A (en) * | 1986-12-24 | 1989-02-28 | Merck & Co., Inc. | Furopyridine sulfonamides and their opthalmological compositions |
DK0689536T3 (da) * | 1993-03-16 | 2001-07-30 | Pfizer | Naphthalenderivater |
US5597826A (en) * | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
DZ2376A1 (fr) * | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
GB9818916D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
GB9904995D0 (en) * | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Substituted aza-oxindole derivatives |
AU1542201A (en) * | 1999-11-05 | 2001-05-14 | Nps Allelix Corp. | Compounds having 5-HT6 receptor antagonist activity |
GB9926302D0 (en) * | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
AU2001264566A1 (en) * | 2000-05-05 | 2001-11-20 | Cor Therapeutics, Inc. | Heterobicyclic sulfonamides and their use as platelet adp receptor inhibitors |
WO2001096336A2 (en) * | 2000-06-14 | 2001-12-20 | Warner-Lambert Company | 6,5-fused bicyclic heterocycles |
EA006132B1 (ru) * | 2000-10-20 | 2005-10-27 | Биовитрум Аб | 2-, 3-, 4- или 5-замещенные n-(1-(арил-, гетероарил- или арилалкил)сульфонил)индолы и их применение в терапии |
NZ528450A (en) * | 2001-05-11 | 2006-02-24 | Biovitrum Ab | Novel, arylsulfonamide compounds for the treatment of obesity, type II diabetes and CNS-disorders |
JP4187642B2 (ja) * | 2001-06-07 | 2008-11-26 | エフ.ホフマン−ラ ロシュ アーゲー | 5−ht6受容体親和性を有する新規インドール誘導体 |
EA008476B1 (ru) * | 2001-06-11 | 2007-06-29 | Биовитрум Аб | Замещенные сульфонамиды, способ их получения и их применение в качестве лечебного средства для лечения расстройств цнс, ожирения и диабета типа ii |
-
2003
- 2003-06-19 MX MXPA04012914A patent/MXPA04012914A/es not_active Application Discontinuation
- 2003-06-19 AU AU2003243091A patent/AU2003243091A1/en not_active Abandoned
- 2003-06-19 EP EP03760999A patent/EP1513828A1/en not_active Ceased
- 2003-06-19 CN CN038144328A patent/CN1662521A/zh active Pending
- 2003-06-19 CA CA002486989A patent/CA2486989A1/en not_active Abandoned
- 2003-06-19 NZ NZ536600A patent/NZ536600A/en unknown
- 2003-06-19 RS YU111204A patent/RS111204A/sr unknown
- 2003-06-19 NZ NZ552282A patent/NZ552282A/en unknown
- 2003-06-19 NZ NZ552283A patent/NZ552283A/en unknown
- 2003-06-19 SG SG200604188-3A patent/SG156524A1/en unknown
- 2003-06-19 EA EA200600975A patent/EA011581B1/ru not_active IP Right Cessation
- 2003-06-19 WO PCT/SE2003/001061 patent/WO2004000828A1/en active Application Filing
- 2003-06-19 BR BR0311952-1A patent/BR0311952A/pt not_active IP Right Cessation
- 2003-06-19 EA EA200500054A patent/EA008835B1/ru not_active IP Right Cessation
-
2004
- 2004-11-04 IL IL16505104A patent/IL165051A0/xx unknown
-
2005
- 2005-01-19 NO NO20050294A patent/NO20050294L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL165051A0 (en) | 2005-12-18 |
CN1662521A (zh) | 2005-08-31 |
EP1513828A1 (en) | 2005-03-16 |
EA008835B1 (ru) | 2007-08-31 |
EA011581B1 (ru) | 2009-04-28 |
MXPA04012914A (es) | 2005-03-31 |
SG156524A1 (en) | 2009-11-26 |
CA2486989A1 (en) | 2003-12-31 |
WO2004000828A1 (en) | 2003-12-31 |
NO20050294L (no) | 2005-02-04 |
NZ536600A (en) | 2007-08-31 |
AU2003243091A1 (en) | 2004-01-06 |
RS111204A (en) | 2006-12-15 |
NZ552282A (en) | 2008-07-31 |
EA200600975A1 (ru) | 2006-10-27 |
EA200500054A1 (ru) | 2005-06-30 |
NZ552283A (en) | 2008-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: BIOVITRUM AB (PUBL) (SE) Free format text: ALTERADO DE: BIOVITRUM AB |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: C07D 207/12, C07D 211/40, C07D 211/46, C07D 215/46, C07D 217/22, C07D 401/04, C07D 406/12, C07D 471/04, C07D 495/04, A61K 31/40, A61K 31/4025, A61K 31/4353, A61K 31/4465, A61K 31/4523, A61K 31/496, A61K 31/551, A61P 25/00, A61P 3/04, A61P 3/10, A61P 3/00, A61P 43/00 Ipc: C07D 401/04 (2011.01), C07D 495/04 (2011.01), C07D |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 8A. ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 8A ANUIDADE. |