BR0308166A - Compostos de derivados de 8-azaprostaglandina e drogas contendo os compostos como o ingrediente ativo - Google Patents
Compostos de derivados de 8-azaprostaglandina e drogas contendo os compostos como o ingrediente ativoInfo
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- BR0308166A BR0308166A BR0308166-4A BR0308166A BR0308166A BR 0308166 A BR0308166 A BR 0308166A BR 0308166 A BR0308166 A BR 0308166A BR 0308166 A BR0308166 A BR 0308166A
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Abstract
"COMPOSTOS DE DERIVADOS DE 8-AZAPROSTAGLANDINA E DROGAS CONTENDO OS COMPOSTOS COMO O INGREDIENTE ATIVO". A 8-azaprostaglandina representada pela seguinte fórmula geral (I), seus sais farmacologicamente aceitáveis ou os clatratos de ciclodextrina da mesma: (I), em que cada símbolo é como definido na descrição. Por causa de ligarem-se fortemente ao subtipo de receptor de PGE EP~ 2~, os compostos representados pela fórmula geral (I) são úteis na prevenção e/ou no tratamento de doenças imunes, doenças alérgicas, morte de célula do nervo, paramenia, nascimento prematuro, aborto, calvície, neuropatia retinal, tal como o glaucoma, disfunção erétil, artrite, lesão pulmonar, fibrose pulmonar, enfisema pulmonar, bronquite, doença pulmonar obstrutiva crónica, lesão hepática, hepatite aguda, cirrose, choque, nefrite, insuficiência renal, doenças circulatórias, síndrome da resposta inflamatória sistêmica, sepse, síndrome de hematófago, síndrome de ativação de macrófagos, doença de Still, doença de Kawasaki, queimadura, granuloma sistêmico, colite ulcerativa, doença de Crohn, hipercitocinemia na diálise, falência múltipla dos órgãos, doenças ósseas e assim por diante.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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JP2002058487 | 2002-03-05 | ||
JP2002216567 | 2002-07-25 | ||
JP2003013447 | 2003-01-22 | ||
PCT/JP2003/002478 WO2003074483A1 (fr) | 2002-03-05 | 2003-03-04 | Composes derives de 8 azaprostaglandine et medicaments contenant ceux-ci comme principe actif |
Publications (1)
Publication Number | Publication Date |
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BR0308166A true BR0308166A (pt) | 2005-01-18 |
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BR0308166-4A BR0308166A (pt) | 2002-03-05 | 2003-03-04 | Compostos de derivados de 8-azaprostaglandina e drogas contendo os compostos como o ingrediente ativo |
Country Status (16)
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US (3) | US7402605B2 (pt) |
EP (1) | EP1481976B1 (pt) |
JP (2) | JP4547912B2 (pt) |
KR (1) | KR100704215B1 (pt) |
CN (1) | CN1653046A (pt) |
AU (1) | AU2003211574A1 (pt) |
BR (1) | BR0308166A (pt) |
CA (1) | CA2477715A1 (pt) |
IL (1) | IL163866A0 (pt) |
MX (1) | MXPA04008596A (pt) |
NO (1) | NO20043702L (pt) |
NZ (1) | NZ535024A (pt) |
PL (1) | PL372084A1 (pt) |
RU (1) | RU2306309C2 (pt) |
TW (1) | TW200305425A (pt) |
WO (1) | WO2003074483A1 (pt) |
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KR20160048054A (ko) | 2013-07-19 | 2016-05-03 | 카이맨 케미칼 컴파니 인코포레이티드 | 골 성장의 촉진을 위한 방법, 시스템 및 조성물 |
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2003
- 2003-03-04 IL IL16386603A patent/IL163866A0/xx unknown
- 2003-03-04 JP JP2003572953A patent/JP4547912B2/ja not_active Expired - Fee Related
- 2003-03-04 US US10/506,536 patent/US7402605B2/en not_active Expired - Fee Related
- 2003-03-04 RU RU2004129584/04A patent/RU2306309C2/ru not_active IP Right Cessation
- 2003-03-04 CA CA002477715A patent/CA2477715A1/en not_active Abandoned
- 2003-03-04 TW TW092104500A patent/TW200305425A/zh unknown
- 2003-03-04 EP EP03743585A patent/EP1481976B1/en not_active Expired - Lifetime
- 2003-03-04 PL PL03372084A patent/PL372084A1/xx not_active Application Discontinuation
- 2003-03-04 WO PCT/JP2003/002478 patent/WO2003074483A1/ja active Application Filing
- 2003-03-04 MX MXPA04008596A patent/MXPA04008596A/es not_active Application Discontinuation
- 2003-03-04 KR KR1020047013858A patent/KR100704215B1/ko not_active IP Right Cessation
- 2003-03-04 CN CNA03810251XA patent/CN1653046A/zh active Pending
- 2003-03-04 BR BR0308166-4A patent/BR0308166A/pt not_active IP Right Cessation
- 2003-03-04 NZ NZ535024A patent/NZ535024A/en unknown
- 2003-03-04 AU AU2003211574A patent/AU2003211574A1/en not_active Abandoned
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2004
- 2004-09-03 NO NO20043702A patent/NO20043702L/no not_active Application Discontinuation
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2008
- 2008-06-13 US US12/139,260 patent/US7683094B2/en not_active Expired - Fee Related
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2009
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Also Published As
Publication number | Publication date |
---|---|
RU2306309C2 (ru) | 2007-09-20 |
KR100704215B1 (ko) | 2007-04-10 |
MXPA04008596A (es) | 2004-12-06 |
IL163866A0 (en) | 2005-12-18 |
US20050124577A1 (en) | 2005-06-09 |
TW200305425A (en) | 2003-11-01 |
US20090042885A1 (en) | 2009-02-12 |
RU2004129584A (ru) | 2005-05-27 |
US7683094B2 (en) | 2010-03-23 |
EP1481976A4 (en) | 2006-01-18 |
PL372084A1 (en) | 2005-07-11 |
JP4547912B2 (ja) | 2010-09-22 |
KR20040095264A (ko) | 2004-11-12 |
US7402605B2 (en) | 2008-07-22 |
AU2003211574A1 (en) | 2003-09-16 |
WO2003074483A1 (fr) | 2003-09-12 |
JP2010077142A (ja) | 2010-04-08 |
EP1481976A1 (en) | 2004-12-01 |
EP1481976B1 (en) | 2012-11-07 |
CA2477715A1 (en) | 2003-09-12 |
CN1653046A (zh) | 2005-08-10 |
US8026273B2 (en) | 2011-09-27 |
NO20043702L (no) | 2004-12-03 |
US20100113388A1 (en) | 2010-05-06 |
JPWO2003074483A1 (ja) | 2005-06-30 |
NZ535024A (en) | 2006-10-27 |
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