BR0214521A - Compostos orgânicos - Google Patents

Compostos orgânicos

Info

Publication number
BR0214521A
BR0214521A BR0214521-9A BR0214521A BR0214521A BR 0214521 A BR0214521 A BR 0214521A BR 0214521 A BR0214521 A BR 0214521A BR 0214521 A BR0214521 A BR 0214521A
Authority
BR
Brazil
Prior art keywords
organic compounds
pleuromutilin
microspheres
antibiotic
question
Prior art date
Application number
BR0214521-9A
Other languages
English (en)
Other versions
BR0214521B1 (pt
Inventor
Susanne Chr Wieland-Berghausen
Ferenc Jozsef Rakoczi
Brigitte Monika Cron-Eckhardt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0214521A publication Critical patent/BR0214521A/pt
Publication of BR0214521B1 publication Critical patent/BR0214521B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/20—Shaping or working-up of animal feeding-stuffs by moulding, e.g. making cakes or briquettes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/25—Shaping or working-up of animal feeding-stuffs by extrusion
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K40/00—Shaping or working-up of animal feeding-stuffs
    • A23K40/30—Shaping or working-up of animal feeding-stuffs by encapsulating; by coating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A23K50/60—Feeding-stuffs specially adapted for particular animals for weanlings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

"COMPOSTOS ORGâNICOS". é descrito o fornecimento de péletes de ração animal, que compreendem, como antibiótico, um derivado de pleuromutilina em forma estabilizada, a saber, na forma de microesférulas. Os derivados de pleuromutilina em questão possuem a fórmula geral I em que R~ 1~ é etila ou vinila, existe uma dupla ligação ou uma ligação simples entre os átomos de carbono 1 e 2, Ra e Rb são, cada um independentemente do outro, hidrogênio ou halogênio, e T é um radical orgânico de cadeia curta ou cadeia longa.
BRPI0214521-9B1A 2001-11-28 2002-11-27 Microesferas contendo derivados de pleuromutilina estabilizados, seu uso e péletes de ração animal BR0214521B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01128276 2001-11-28
EP01128276.1 2001-11-28
PCT/EP2002/013388 WO2003045354A1 (en) 2001-11-28 2002-11-27 Micropherules containing a pleuromutilin derivative

Publications (2)

Publication Number Publication Date
BR0214521A true BR0214521A (pt) 2004-10-26
BR0214521B1 BR0214521B1 (pt) 2014-05-27

Family

ID=8179384

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0214521-9B1A BR0214521B1 (pt) 2001-11-28 2002-11-27 Microesferas contendo derivados de pleuromutilina estabilizados, seu uso e péletes de ração animal

Country Status (21)

Country Link
US (1) US8236851B2 (pt)
EP (1) EP1450767B1 (pt)
JP (1) JP4537708B2 (pt)
KR (1) KR100965017B1 (pt)
CN (1) CN100348185C (pt)
AR (1) AR038367A1 (pt)
AT (1) ATE363270T1 (pt)
AU (1) AU2002356740B2 (pt)
BR (1) BR0214521B1 (pt)
CA (1) CA2466671C (pt)
CO (1) CO5390081A1 (pt)
CY (1) CY1106745T1 (pt)
DE (1) DE60220436T2 (pt)
DK (1) DK1450767T3 (pt)
ES (1) ES2284980T3 (pt)
MX (1) MXPA04005186A (pt)
NZ (1) NZ533085A (pt)
PT (1) PT1450767E (pt)
RU (1) RU2296004C2 (pt)
WO (1) WO2003045354A1 (pt)
ZA (1) ZA200403801B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101690717B (zh) * 2009-09-30 2013-03-06 北京大北农动物保健科技有限责任公司 一种兽用沃尼妙林及其盐的预混剂及制备方法
US20110269657A1 (en) * 2010-04-28 2011-11-03 Jiten Odhavji Dihora Delivery particles
CZ308210B6 (cs) * 2011-11-02 2020-03-04 Veterinární A Farmaceutická Univerzita Brno Farmaceutická kompozice ve formě pelet majících velikost částic v rozmezí od 0,1 do 10 mm pro perorální podání vodním živočichům a způsob její výroby
CN102512376A (zh) * 2011-11-29 2012-06-27 河南牧翔动物药业有限公司 一种沃尼妙林凝胶微球及其制备方法
CN102579364B (zh) * 2012-03-05 2013-10-09 河北科技大学 沃尼妙林/沃尼妙林盐的缓控释微球及其制备方法
CN103948567B (zh) * 2014-04-17 2015-10-14 江苏省家禽科学研究所 一种泰妙菌素微囊制剂的制备方法
CN108926536A (zh) * 2017-05-22 2018-12-04 北京科百大科技有限责任公司 一种稳定的盐酸沃尼妙林组合物的制备方法
CN108484424A (zh) * 2018-04-08 2018-09-04 中国农业科学院兰州畜牧与兽药研究所 侧链含有季铵盐基团的截短侧耳素类衍生物及其用途
KR102098289B1 (ko) * 2018-04-11 2020-04-07 경북대학교 산학협력단 발네물린을 유효성분으로 함유하는 골 질환 예방 또는 치료용 조성물

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA923384A (en) 1970-02-03 1973-03-27 Abe Jinnosuke Process for preparing a micro capsule
US3919290A (en) * 1972-10-03 1975-11-11 Sandoz Ltd Substituted 14-desoxy-mutilins
US3987194A (en) * 1975-05-12 1976-10-19 E. R. Squibb & Sons, Inc. Use of pleuromutilin derivatives for the treatment of swine dysentery
US4086359A (en) * 1975-09-30 1978-04-25 E. R. Squibb & Sons, Inc. Derivatives of pleuromutilin and compositions
JPS58148816A (ja) * 1982-02-27 1983-09-05 Nippon Zenyaku Kogyo Kk 低刺激性チアムリン注射剤
DE3560511D1 (en) 1984-02-17 1987-10-01 Sandoz Ag Pleuromutilin derivatives, process for their preparation and their use
DE3422782A1 (de) 1984-06-20 1986-01-02 Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim Zinkbacitracin enthaltender futtermittelzusatz
JPH072638B2 (ja) 1986-07-28 1995-01-18 日本化薬株式会社 経口投与用製剤
US5460817A (en) * 1988-01-19 1995-10-24 Allied Colloids Ltd. Particulate composition comprising a core of matrix polymer with active ingredient distributed therein
JP2854034B2 (ja) * 1989-09-13 1999-02-03 ノバルティス アクチエンゲゼルシャフト 粒状動物用医薬組成物
JPH041132A (ja) * 1990-04-18 1992-01-06 Sds Biotech Kk 魚類の細菌性疾患の予防・治療剤
AT400674B (de) * 1991-07-24 1996-02-26 Biochemie Gmbh Pharmazeutische pleuromutilin-zubereitung
DE4308282C2 (de) * 1993-03-16 1994-12-22 Beiersdorf Ag Vorzugsweise in Form von Mikrosphärulen vorliegende galenische Matrices
IT1265290B1 (it) * 1993-12-17 1996-10-31 Dox Al Italia Spa Miscele ad elevato contenuto di sostanze attive idonee ad essere distribuite in modo omogeneo nei mangimi per animali.
GB9406094D0 (en) * 1994-03-28 1994-05-18 Univ Nottingham And University Polymer microspheres and a method of production thereof
ATE228773T1 (de) 1994-10-20 2002-12-15 Chevita Tierarzneimittel Ges M Verfahren zur herstellung von futtermitteln, die pharmakologisch wirksame substanzen enthalten
US5614222A (en) * 1994-10-25 1997-03-25 Kaplan; Milton R. Stable aqueous drug suspensions and methods for preparation thereof
GB9500863D0 (en) * 1995-01-17 1995-03-08 Grampian Pharm Ltd Medicated animal foodstuffs
US5607697A (en) * 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
GB9614017D0 (en) 1996-07-04 1996-09-04 Biochemie Gmbh Organic compounds
KR100516418B1 (ko) * 1996-07-04 2005-12-20 바이오케미 게젤샤프트 엠베하 플루로뮤틸린유도체의수의학적용도
KR100302314B1 (ko) * 1998-05-12 2002-04-24 김종인 세파클로르의서방성매트릭스제형
TWI260220B (en) 1999-11-22 2006-08-21 Novartis Ag A pharmaceutical composition for the transdermal treatment of bacterial infections in animals
TWI228048B (en) * 1999-12-09 2005-02-21 Novartis Ag New formulation

Also Published As

Publication number Publication date
JP4537708B2 (ja) 2010-09-08
WO2003045354A8 (en) 2004-08-26
ES2284980T3 (es) 2007-11-16
KR100965017B1 (ko) 2010-06-21
NZ533085A (en) 2005-10-28
DE60220436D1 (de) 2007-07-12
DK1450767T3 (da) 2007-08-13
CO5390081A1 (es) 2004-04-30
AU2002356740A1 (en) 2003-06-10
US20050070486A1 (en) 2005-03-31
CN1592608A (zh) 2005-03-09
RU2004119815A (ru) 2006-01-10
PT1450767E (pt) 2007-09-05
BR0214521B1 (pt) 2014-05-27
WO2003045354A1 (en) 2003-06-05
CY1106745T1 (el) 2012-05-23
ZA200403801B (en) 2006-05-31
KR20040058334A (ko) 2004-07-03
MXPA04005186A (es) 2004-08-11
EP1450767B1 (en) 2007-05-30
CA2466671C (en) 2011-03-29
JP2005523243A (ja) 2005-08-04
US8236851B2 (en) 2012-08-07
AR038367A1 (es) 2005-01-12
CN100348185C (zh) 2007-11-14
EP1450767A1 (en) 2004-09-01
CA2466671A1 (en) 2003-06-05
ATE363270T1 (de) 2007-06-15
RU2296004C2 (ru) 2007-03-27
DE60220436T2 (de) 2008-01-31
AU2002356740B2 (en) 2006-06-15

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/05/2014, OBSERVADAS AS CONDICOES LEGAIS.

B25C Requirement related to requested transfer of rights

Free format text: A FIM DE ATENDER A TRANSFERENCIA REQUERIDA ATRAVES DA PETICAO NO 20150005906 DE 23/03/2015 , E NECESSARIO REAPRESENTAR O DOCUMENTO DE CESSAO COM AS ASSINATURAS NOTARIZADAS E A DEVIDA LEGALIZACAO CONSULAR.

B25B Requested transfer of rights rejected
B25C Requirement related to requested transfer of rights
B25C Requirement related to requested transfer of rights
B15K Others concerning applications: alteration of classification

Ipc: A61K 9/16 (2006.01), A23K 20/195 (2016.01), A23K 4

B25A Requested transfer of rights approved
B25D Requested change of name of applicant approved
B25G Requested change of headquarter approved