BR0214075A - Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação - Google Patents
Dosagem unitária que compreende um análogo de prostaglandina para tratar constipaçãoInfo
- Publication number
- BR0214075A BR0214075A BR0214075-6A BR0214075A BR0214075A BR 0214075 A BR0214075 A BR 0214075A BR 0214075 A BR0214075 A BR 0214075A BR 0214075 A BR0214075 A BR 0214075A
- Authority
- BR
- Brazil
- Prior art keywords
- unit dosage
- prostaglandin analog
- constipation
- treat constipation
- analog
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C53/00—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
- C07C53/15—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
- C07C53/23—Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen containing rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
Abstract
"DOSAGEM UNITáRIA QUE COMPREENDE UM ANáLOGO DE PROSTAGLANDINA PARA TRATAR CONSTIPAçãO". A presente invenção refere-se a uma dosagem unitária para tratar constipação em um paciente humano. A dosagem unitária da invenção compreende um análogo de prostaglandina halogenado e um excipiente farmaceuticamente adequado. A dosagem unitária alivia constipação sem efeitos colaterais substanciais.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33131601P | 2001-11-14 | 2001-11-14 | |
PCT/JP2002/011862 WO2003041716A1 (en) | 2001-11-14 | 2002-11-14 | Dosage unit comprising a prostaglandin analog for treating constipation |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0214075A true BR0214075A (pt) | 2004-09-28 |
Family
ID=23293447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0214075-6A BR0214075A (pt) | 2001-11-14 | 2002-11-14 | Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação |
Country Status (15)
Country | Link |
---|---|
US (3) | US8097653B2 (pt) |
EP (2) | EP2298314B1 (pt) |
JP (2) | JP4852229B2 (pt) |
AR (3) | AR037524A1 (pt) |
AT (1) | ATE522218T1 (pt) |
BR (1) | BR0214075A (pt) |
CA (1) | CA2464420C (pt) |
CY (1) | CY1115856T1 (pt) |
DK (2) | DK2298314T3 (pt) |
ES (2) | ES2368729T3 (pt) |
HK (1) | HK1155649A1 (pt) |
LU (1) | LU92826I2 (pt) |
PT (2) | PT2298314E (pt) |
TW (1) | TWI331920B (pt) |
WO (1) | WO2003041716A1 (pt) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI331920B (en) | 2001-11-14 | 2010-10-21 | Sucampo Ag | Unit dosage form for relieving or treating constipation in human patients |
AU2003274735B2 (en) * | 2002-10-23 | 2008-12-04 | Sucampo Ag | Prostaglandin compounds for the treatment of obesity |
NZ541110A (en) | 2002-12-27 | 2008-11-28 | Sucampo Ag | Derivatives of prostaglandins for treating abdominal discomfort |
JP5294559B2 (ja) * | 2003-07-03 | 2013-09-18 | スキャンポ・アーゲー | クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物 |
TWI387454B (zh) * | 2004-09-02 | 2013-03-01 | Sucampo Ag | 治療胃腸道疾病之方法及組成物 |
US8524731B2 (en) | 2005-03-07 | 2013-09-03 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
US9662325B2 (en) | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
US9662390B2 (en) * | 2005-03-07 | 2017-05-30 | The University Of Chicago | Use of opioid antagonists to attenuate endothelial cell proliferation and migration |
US8518962B2 (en) | 2005-03-07 | 2013-08-27 | The University Of Chicago | Use of opioid antagonists |
US20060281818A1 (en) | 2005-03-21 | 2006-12-14 | Sucampo Ag, North Carolina State University | Method for treating mucosal disorders |
DK1871380T3 (da) * | 2005-04-12 | 2011-11-21 | Sucampo Ag | Kombineret anvendelse af prostaglandinforbindelse og protonpumpeinhibitor til behandlingen af gastrointestinale lidelser |
EP2682130A1 (en) | 2006-01-24 | 2014-01-08 | R-Tech Ueno, Ltd. | Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound |
KR101393944B1 (ko) * | 2006-01-24 | 2014-05-12 | 수캄포 아게 | 연질-젤라틴 캡슐 제형물 |
US20090012165A1 (en) | 2007-07-03 | 2009-01-08 | Sucampo Ag | Pharmaceutical combination of nsaid and prostaglandin compound |
US20090030072A1 (en) | 2007-07-03 | 2009-01-29 | Sucampo Ag | Pharmaceutical combination of opioid and prostaglandin compound |
NZ598783A (en) * | 2009-09-18 | 2013-07-26 | Adolor Corp | Use of opioid receptor antagonist for gastrointestinal tract disorders |
WO2014159679A1 (en) | 2013-03-12 | 2014-10-02 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Methods for using lubiprostone to absorb fluid from the subretinal space |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5350141A (en) * | 1976-10-18 | 1978-05-08 | Ono Pharmaceut Co Ltd | Stabilization of prostaglandin and prostaglandin analogues |
GB1581886A (en) | 1977-05-26 | 1980-12-31 | May & Baker Ltd | Prostanol derivatives |
JPH0681728B2 (ja) | 1987-10-02 | 1994-10-19 | 株式会社上野製薬応用研究所 | 下 剤 |
GB2210556B (en) * | 1987-10-02 | 1991-07-17 | Ueno Seiyaku Oyo Kenkyujo Kk | The use of 15-keto-16-halo-prostaglandins in cathartic compositions |
US5317032A (en) | 1987-10-02 | 1994-05-31 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Prostaglandin cathartic |
JP2579193B2 (ja) | 1988-07-19 | 1997-02-05 | 小野薬品工業株式会社 | 16,16−ジフルオロ−15−オキソ−15−デオキシpge誘導体 |
CA2027814C (en) * | 1989-10-20 | 1996-07-30 | Ryuji Ueno | Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds |
CA2030345C (en) * | 1989-11-22 | 1998-12-08 | Ryuji Ueno | Use of 15-keto-prostaglandin compound for improvement of encephalic function |
CA2030344C (en) | 1989-11-22 | 2000-04-18 | Ryuji Ueno | Treatment of pulmonary dysfunction with 15-keto-prostaglandin compounds |
CA2030346C (en) | 1989-11-22 | 2000-04-11 | Ryuji Ueno | Treatment of cardiac dysfunction with 15-keto-prostaglandin compounds |
EP0455448B1 (en) * | 1990-05-01 | 1998-12-09 | R-Tech Ueno Ltd. | Treatment of pancreatic disease with 15-keto-prostaglandin E compounds |
CA2046069C (en) * | 1990-07-10 | 2002-04-09 | Ryuji Ueno | Treatment of inflammatory diseases with 15-keto-prostaglandin compounds |
JP2938579B2 (ja) | 1990-12-15 | 1999-08-23 | 株式会社上野製薬応用研究所 | 消化管壁保護剤 |
DE69213057T2 (de) * | 1991-03-14 | 1997-01-09 | Ueno Seiyaku Oyo Kenkyujo Kk | Stimulierung von Wundheilung mit 15-Keto-prostaglandinverbindungen |
ES2118842T3 (es) * | 1992-02-04 | 1998-10-01 | Eisai Co Ltd | Derivados del acido aminobenzoico. |
CA2150287C (en) * | 1994-06-03 | 2004-08-10 | Ryuji Ueno | Agent for treating hepato-biliary diseases |
JP3183615B2 (ja) * | 1994-06-03 | 2001-07-09 | 株式会社アールテック・ウエノ | 肝・胆道系疾患処置剤 |
JP3187438B2 (ja) * | 1996-06-10 | 2001-07-11 | 株式会社アールテック・ウエノ | エンドセリン拮抗剤 |
DE19717005A1 (de) * | 1997-04-23 | 1998-10-29 | Kennametal Inc | Spannfutter für Rundlaufwerkzeuge |
NZ336960A (en) * | 1997-11-28 | 2001-02-23 | R Tech Ueno Ltd | Use of 15-keto-prostaglandin E compounds for the preparation of medicaments for use as endothelin antagonists |
US6492417B1 (en) | 1997-12-22 | 2002-12-10 | Alcon Manufacturing, Ltd. | 11-deoxy-16-fluoro-PGF2α analogs as FP receptor antagonists |
TR200201032T2 (tr) | 1999-10-15 | 2002-08-21 | Sucampo Ag | yeni terkip ve stabilizasyon yöntemi. |
CA2404767C (en) | 2000-04-06 | 2010-12-07 | Sucampo Ag | Bile secretion promoting composition containing a 15-keto prostaglandin |
US6414016B1 (en) | 2000-09-05 | 2002-07-02 | Sucampo, A.G. | Anti-constipation composition |
TWI302100B (en) | 2001-05-02 | 2008-10-21 | Sucampo Ag | Composition for treating drug-induced constipation |
KR100867295B1 (ko) | 2001-05-18 | 2008-11-06 | 수캄포 아게 | 하제 조성물 |
NZ531503A (en) * | 2001-08-31 | 2006-01-27 | Sucampo Ag | Prostaglandin analogs as chloride channel opener |
TWI331920B (en) | 2001-11-14 | 2010-10-21 | Sucampo Ag | Unit dosage form for relieving or treating constipation in human patients |
US7732487B2 (en) | 2001-11-19 | 2010-06-08 | Sucampo Ag | Method for treating a disease or condition responsive to opening of C1C-2 channel |
NZ541110A (en) * | 2002-12-27 | 2008-11-28 | Sucampo Ag | Derivatives of prostaglandins for treating abdominal discomfort |
-
2002
- 2002-11-13 TW TW091133227A patent/TWI331920B/zh not_active IP Right Cessation
- 2002-11-13 AR ARP020104349A patent/AR037524A1/es not_active Application Discontinuation
- 2002-11-14 PT PT100102110T patent/PT2298314E/pt unknown
- 2002-11-14 CA CA2464420A patent/CA2464420C/en not_active Expired - Lifetime
- 2002-11-14 EP EP10010211.0A patent/EP2298314B1/en not_active Expired - Lifetime
- 2002-11-14 PT PT02780083T patent/PT1443938E/pt unknown
- 2002-11-14 BR BR0214075-6A patent/BR0214075A/pt not_active Application Discontinuation
- 2002-11-14 JP JP2003543603A patent/JP4852229B2/ja not_active Expired - Lifetime
- 2002-11-14 DK DK10010211.0T patent/DK2298314T3/en active
- 2002-11-14 AT AT02780083T patent/ATE522218T1/de active
- 2002-11-14 EP EP02780083A patent/EP1443938B1/en not_active Expired - Lifetime
- 2002-11-14 DK DK02780083.8T patent/DK1443938T3/da active
- 2002-11-14 US US10/293,516 patent/US8097653B2/en not_active Expired - Lifetime
- 2002-11-14 ES ES02780083T patent/ES2368729T3/es not_active Expired - Lifetime
- 2002-11-14 WO PCT/JP2002/011862 patent/WO2003041716A1/en active Application Filing
- 2002-11-14 ES ES10010211.0T patent/ES2524369T3/es not_active Expired - Lifetime
-
2011
- 2011-05-25 JP JP2011117231A patent/JP2011201905A/ja active Pending
- 2011-09-21 HK HK11109944.5A patent/HK1155649A1/xx not_active IP Right Cessation
- 2011-12-20 US US13/330,942 patent/US8389542B2/en not_active Expired - Lifetime
-
2013
- 2013-01-30 US US13/754,138 patent/US20130143958A1/en not_active Abandoned
-
2014
- 2014-11-28 CY CY20141100997T patent/CY1115856T1/el unknown
- 2014-12-30 AR ARP140104956A patent/AR098997A2/es unknown
-
2015
- 2015-09-11 LU LU92826C patent/LU92826I2/xx unknown
-
2019
- 2019-03-21 AR ARP190100714A patent/AR117404A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1443938B1 (en) | 2011-08-31 |
US20120088824A1 (en) | 2012-04-12 |
LU92826I2 (fr) | 2015-11-24 |
TWI331920B (en) | 2010-10-21 |
HK1155649A1 (en) | 2012-05-25 |
PT2298314E (pt) | 2014-12-03 |
PT1443938E (pt) | 2011-09-27 |
US20130143958A1 (en) | 2013-06-06 |
DK1443938T3 (da) | 2011-09-26 |
AR037524A1 (es) | 2004-11-17 |
AR117404A2 (es) | 2021-08-04 |
ES2368729T3 (es) | 2011-11-21 |
JP4852229B2 (ja) | 2012-01-11 |
TW200300091A (en) | 2003-05-16 |
JP2005513014A (ja) | 2005-05-12 |
CA2464420A1 (en) | 2003-05-22 |
US8389542B2 (en) | 2013-03-05 |
EP2298314A1 (en) | 2011-03-23 |
JP2011201905A (ja) | 2011-10-13 |
WO2003041716A1 (en) | 2003-05-22 |
AR098997A2 (es) | 2016-06-22 |
US8097653B2 (en) | 2012-01-17 |
DK2298314T3 (en) | 2014-12-01 |
US20030119898A1 (en) | 2003-06-26 |
ATE522218T1 (de) | 2011-09-15 |
CY1115856T1 (el) | 2017-01-25 |
ES2524369T3 (es) | 2014-12-05 |
EP2298314B1 (en) | 2014-09-03 |
EP1443938A1 (en) | 2004-08-11 |
CA2464420C (en) | 2011-12-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B12B | Appeal against refusal [chapter 12.2 patent gazette] |