BR0214075A - Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação - Google Patents

Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação

Info

Publication number
BR0214075A
BR0214075A BR0214075-6A BR0214075A BR0214075A BR 0214075 A BR0214075 A BR 0214075A BR 0214075 A BR0214075 A BR 0214075A BR 0214075 A BR0214075 A BR 0214075A
Authority
BR
Brazil
Prior art keywords
unit dosage
prostaglandin analog
constipation
treat constipation
analog
Prior art date
Application number
BR0214075-6A
Other languages
English (en)
Inventor
Ryuji Ueno
Myra L Patchen
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23293447&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0214075(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Publication of BR0214075A publication Critical patent/BR0214075A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C53/00Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen
    • C07C53/15Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen
    • C07C53/23Saturated compounds having only one carboxyl group bound to an acyclic carbon atom or hydrogen containing halogen containing rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)

Abstract

"DOSAGEM UNITáRIA QUE COMPREENDE UM ANáLOGO DE PROSTAGLANDINA PARA TRATAR CONSTIPAçãO". A presente invenção refere-se a uma dosagem unitária para tratar constipação em um paciente humano. A dosagem unitária da invenção compreende um análogo de prostaglandina halogenado e um excipiente farmaceuticamente adequado. A dosagem unitária alivia constipação sem efeitos colaterais substanciais.
BR0214075-6A 2001-11-14 2002-11-14 Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação BR0214075A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33131601P 2001-11-14 2001-11-14
PCT/JP2002/011862 WO2003041716A1 (en) 2001-11-14 2002-11-14 Dosage unit comprising a prostaglandin analog for treating constipation

Publications (1)

Publication Number Publication Date
BR0214075A true BR0214075A (pt) 2004-09-28

Family

ID=23293447

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214075-6A BR0214075A (pt) 2001-11-14 2002-11-14 Dosagem unitária que compreende um análogo de prostaglandina para tratar constipação

Country Status (15)

Country Link
US (3) US8097653B2 (pt)
EP (2) EP2298314B1 (pt)
JP (2) JP4852229B2 (pt)
AR (3) AR037524A1 (pt)
AT (1) ATE522218T1 (pt)
BR (1) BR0214075A (pt)
CA (1) CA2464420C (pt)
CY (1) CY1115856T1 (pt)
DK (2) DK2298314T3 (pt)
ES (2) ES2368729T3 (pt)
HK (1) HK1155649A1 (pt)
LU (1) LU92826I2 (pt)
PT (2) PT2298314E (pt)
TW (1) TWI331920B (pt)
WO (1) WO2003041716A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
AU2003274735B2 (en) * 2002-10-23 2008-12-04 Sucampo Ag Prostaglandin compounds for the treatment of obesity
NZ541110A (en) 2002-12-27 2008-11-28 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
JP5294559B2 (ja) * 2003-07-03 2013-09-18 スキャンポ・アーゲー クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物
TWI387454B (zh) * 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US9662390B2 (en) * 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
DK1871380T3 (da) * 2005-04-12 2011-11-21 Sucampo Ag Kombineret anvendelse af prostaglandinforbindelse og protonpumpeinhibitor til behandlingen af gastrointestinale lidelser
EP2682130A1 (en) 2006-01-24 2014-01-08 R-Tech Ueno, Ltd. Pharmaceutical composition comprising a bi-cyclic compound and method for stabilizing the bi-cyclic compound
KR101393944B1 (ko) * 2006-01-24 2014-05-12 수캄포 아게 연질-젤라틴 캡슐 제형물
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
NZ598783A (en) * 2009-09-18 2013-07-26 Adolor Corp Use of opioid receptor antagonist for gastrointestinal tract disorders
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5350141A (en) * 1976-10-18 1978-05-08 Ono Pharmaceut Co Ltd Stabilization of prostaglandin and prostaglandin analogues
GB1581886A (en) 1977-05-26 1980-12-31 May & Baker Ltd Prostanol derivatives
JPH0681728B2 (ja) 1987-10-02 1994-10-19 株式会社上野製薬応用研究所 下 剤
GB2210556B (en) * 1987-10-02 1991-07-17 Ueno Seiyaku Oyo Kenkyujo Kk The use of 15-keto-16-halo-prostaglandins in cathartic compositions
US5317032A (en) 1987-10-02 1994-05-31 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Prostaglandin cathartic
JP2579193B2 (ja) 1988-07-19 1997-02-05 小野薬品工業株式会社 16,16−ジフルオロ−15−オキソ−15−デオキシpge誘導体
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
CA2030345C (en) * 1989-11-22 1998-12-08 Ryuji Ueno Use of 15-keto-prostaglandin compound for improvement of encephalic function
CA2030344C (en) 1989-11-22 2000-04-18 Ryuji Ueno Treatment of pulmonary dysfunction with 15-keto-prostaglandin compounds
CA2030346C (en) 1989-11-22 2000-04-11 Ryuji Ueno Treatment of cardiac dysfunction with 15-keto-prostaglandin compounds
EP0455448B1 (en) * 1990-05-01 1998-12-09 R-Tech Ueno Ltd. Treatment of pancreatic disease with 15-keto-prostaglandin E compounds
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
JP2938579B2 (ja) 1990-12-15 1999-08-23 株式会社上野製薬応用研究所 消化管壁保護剤
DE69213057T2 (de) * 1991-03-14 1997-01-09 Ueno Seiyaku Oyo Kenkyujo Kk Stimulierung von Wundheilung mit 15-Keto-prostaglandinverbindungen
ES2118842T3 (es) * 1992-02-04 1998-10-01 Eisai Co Ltd Derivados del acido aminobenzoico.
CA2150287C (en) * 1994-06-03 2004-08-10 Ryuji Ueno Agent for treating hepato-biliary diseases
JP3183615B2 (ja) * 1994-06-03 2001-07-09 株式会社アールテック・ウエノ 肝・胆道系疾患処置剤
JP3187438B2 (ja) * 1996-06-10 2001-07-11 株式会社アールテック・ウエノ エンドセリン拮抗剤
DE19717005A1 (de) * 1997-04-23 1998-10-29 Kennametal Inc Spannfutter für Rundlaufwerkzeuge
NZ336960A (en) * 1997-11-28 2001-02-23 R Tech Ueno Ltd Use of 15-keto-prostaglandin E compounds for the preparation of medicaments for use as endothelin antagonists
US6492417B1 (en) 1997-12-22 2002-12-10 Alcon Manufacturing, Ltd. 11-deoxy-16-fluoro-PGF2α analogs as FP receptor antagonists
TR200201032T2 (tr) 1999-10-15 2002-08-21 Sucampo Ag yeni terkip ve stabilizasyon yöntemi.
CA2404767C (en) 2000-04-06 2010-12-07 Sucampo Ag Bile secretion promoting composition containing a 15-keto prostaglandin
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
KR100867295B1 (ko) 2001-05-18 2008-11-06 수캄포 아게 하제 조성물
NZ531503A (en) * 2001-08-31 2006-01-27 Sucampo Ag Prostaglandin analogs as chloride channel opener
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
US7732487B2 (en) 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
NZ541110A (en) * 2002-12-27 2008-11-28 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort

Also Published As

Publication number Publication date
EP1443938B1 (en) 2011-08-31
US20120088824A1 (en) 2012-04-12
LU92826I2 (fr) 2015-11-24
TWI331920B (en) 2010-10-21
HK1155649A1 (en) 2012-05-25
PT2298314E (pt) 2014-12-03
PT1443938E (pt) 2011-09-27
US20130143958A1 (en) 2013-06-06
DK1443938T3 (da) 2011-09-26
AR037524A1 (es) 2004-11-17
AR117404A2 (es) 2021-08-04
ES2368729T3 (es) 2011-11-21
JP4852229B2 (ja) 2012-01-11
TW200300091A (en) 2003-05-16
JP2005513014A (ja) 2005-05-12
CA2464420A1 (en) 2003-05-22
US8389542B2 (en) 2013-03-05
EP2298314A1 (en) 2011-03-23
JP2011201905A (ja) 2011-10-13
WO2003041716A1 (en) 2003-05-22
AR098997A2 (es) 2016-06-22
US8097653B2 (en) 2012-01-17
DK2298314T3 (en) 2014-12-01
US20030119898A1 (en) 2003-06-26
ATE522218T1 (de) 2011-09-15
CY1115856T1 (el) 2017-01-25
ES2524369T3 (es) 2014-12-05
EP2298314B1 (en) 2014-09-03
EP1443938A1 (en) 2004-08-11
CA2464420C (en) 2011-12-13

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]