TR200201032T2 - yeni terkip ve stabilizasyon yöntemi. - Google Patents

yeni terkip ve stabilizasyon yöntemi.

Info

Publication number
TR200201032T2
TR200201032T2 TR2002/01032T TR200201032T TR200201032T2 TR 200201032 T2 TR200201032 T2 TR 200201032T2 TR 2002/01032 T TR2002/01032 T TR 2002/01032T TR 200201032 T TR200201032 T TR 200201032T TR 200201032 T2 TR200201032 T2 TR 200201032T2
Authority
TR
Turkey
Prior art keywords
new composition
stabilization method
glyceride
compound
stabilization
Prior art date
Application number
TR2002/01032T
Other languages
English (en)
Inventor
Ueno Ryuji
Habe Tsuyoshi
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22573018&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200201032(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Publication of TR200201032T2 publication Critical patent/TR200201032T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Farmakolojik aktivitesi olan belli bir bisiklik bilesim ile bir gliseridden olusan yeni bir terkip açiklanmaktadir. Bisiklik bilesimin stabilizasyonu, bilesimin bir gliseridde eriritilmesiyle önemli ölçüde iyilestirilebilir.
TR2002/01032T 1999-10-15 2000-10-13 yeni terkip ve stabilizasyon yöntemi. TR200201032T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15954999P 1999-10-15 1999-10-15

Publications (1)

Publication Number Publication Date
TR200201032T2 true TR200201032T2 (tr) 2002-08-21

Family

ID=22573018

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2002/01032T TR200201032T2 (tr) 1999-10-15 2000-10-13 yeni terkip ve stabilizasyon yöntemi.

Country Status (26)

Country Link
US (5) US6583174B1 (tr)
EP (2) EP1220849B1 (tr)
JP (2) JP4332316B2 (tr)
KR (1) KR100830061B1 (tr)
CN (1) CN1268623C (tr)
AR (3) AR026046A1 (tr)
AT (2) ATE402925T2 (tr)
AU (2) AU780342B2 (tr)
BR (1) BRPI0014869B8 (tr)
CA (1) CA2385732C (tr)
CZ (1) CZ303625B6 (tr)
DE (2) DE60010913T2 (tr)
DK (2) DK1426361T4 (tr)
ES (2) ES2309410T5 (tr)
HK (2) HK1045693B (tr)
HU (2) HU229547B1 (tr)
IL (2) IL148803A0 (tr)
MX (1) MXPA02003756A (tr)
NO (1) NO330258B1 (tr)
NZ (1) NZ518020A (tr)
PT (2) PT1220849E (tr)
RU (1) RU2695274C3 (tr)
TR (1) TR200201032T2 (tr)
TW (1) TWI281918B (tr)
WO (1) WO2001027099A2 (tr)
ZA (1) ZA200202312B (tr)

Families Citing this family (30)

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Publication number Priority date Publication date Assignee Title
CZ303625B6 (cs) * 1999-10-15 2013-01-16 Sucampo Ag Stabilní farmaceutický prostredek obsahující bicyklickou slouceninu a acyglycerol, bicyklická sloucenina, zpusob stabilizace bicyklické slouceniny, farmaceutický prostredek obsahující bicyklickou slouceninu
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
AR037524A1 (es) * 2001-11-14 2004-11-17 Sucampo Ag Unidad de dosificacion que comprende un analogo de prostaglandina para el tratamiento de la constipacion
FR2842810B1 (fr) * 2002-07-25 2006-01-27 Inst Nat Sciences Appliq Nouveaux composes gem difluores, leur procedes de preparation et leurs applications.
PT1562604E (pt) * 2002-10-23 2012-04-09 Sucampo Ag Compostos de prostaglandina para o tratamento de obesidade
CA2510051C (en) * 2002-12-27 2016-07-05 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
DE602004030245D1 (de) * 2003-07-03 2011-01-05 Sucampo Ag Pharmazeutische magensaftresistent überzogene zusammensetzung enthaltend prostaglandin-analoga als chloridkanalöffner
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
TWI387454B (zh) 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
EP1871380B1 (en) * 2005-04-12 2011-10-19 Sucampo AG Combined use of prostaglandin compound and proton pump inhibitor for the treatment of gastrointestinal disorders
BRPI0707333B8 (pt) * 2006-01-24 2021-05-25 R Tech Ueno Ltd composição farmacêutica que compreende um composto bicíclico, método de estabilização do composto bicíclico e formulação de cápsula de gelatina mole
US8026393B2 (en) 2006-01-24 2011-09-27 Sucampo Ag Soft-gelatin capsule formulation
CN103804338A (zh) * 2006-02-07 2014-05-21 株式会社·R-技术上野 用于制备***素衍生物的方法
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090030072A1 (en) 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
NZ583203A (en) 2007-07-19 2011-10-28 Sucampo Ag Pharmaceutical composition comprising 11-deoxy-prostaglandin compound and method for stabilizing the compound
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US8569279B2 (en) * 2009-05-27 2013-10-29 Sucampo Ag Method for modulating claudin mediated functions
US20110034424A1 (en) * 2009-06-30 2011-02-10 Sucampo Ag Method for the long term nsaid use
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US8940790B2 (en) 2009-11-03 2015-01-27 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
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US9150537B2 (en) 2011-01-27 2015-10-06 Ono Pharmaceutical Co., Ltd. Bicyclic compound and use thereof for medical purposes
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
WO2016161085A1 (en) 2015-04-01 2016-10-06 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
EP3480191B1 (en) 2016-06-30 2021-09-01 ONO Pharmaceutical Co., Ltd. Method for producing bicyclic compound
JP6957610B2 (ja) 2016-10-06 2021-11-02 スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ 医薬品用途のための多層ビーズ
JPWO2019221215A1 (ja) * 2018-05-18 2021-05-27 ニプロ株式会社 ルビプロストン含有粒子状医薬組成物

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Also Published As

Publication number Publication date
EP1220849B1 (en) 2004-05-19
EP1426361B1 (en) 2008-07-30
CA2385732A1 (en) 2001-04-19
US8097649B1 (en) 2012-01-17
DE60010913T2 (de) 2005-06-09
ZA200202312B (en) 2002-12-24
EP1426361B2 (en) 2015-02-25
CN1268623C (zh) 2006-08-09
DK1220849T3 (da) 2004-09-27
CA2385732C (en) 2009-02-10
IL148803A (en) 2006-07-05
TWI281918B (en) 2007-06-01
DK1426361T4 (en) 2015-03-16
AU780342B2 (en) 2005-03-17
RU2695274C9 (ru) 2020-01-22
WO2001027099A3 (en) 2001-10-25
PT1426361E (pt) 2008-10-08
NO330258B1 (no) 2011-03-14
JP4332316B2 (ja) 2009-09-16
EP1426361A1 (en) 2004-06-09
HUP0203746A3 (en) 2005-02-28
CZ303625B6 (cs) 2013-01-16
IL148803A0 (en) 2002-09-12
HUP1300369A2 (tr) 2003-03-28
ATE267189T1 (de) 2004-06-15
HK1045693A1 (en) 2002-12-06
HU230484B1 (hu) 2016-07-28
US6583174B1 (en) 2003-06-24
AU7685600A (en) 2001-04-23
KR100830061B1 (ko) 2008-05-16
AU2004242503B2 (en) 2007-06-21
AU2004242503C1 (en) 2005-01-27
HK1045693B (zh) 2005-01-21
BR0014869A (pt) 2002-06-25
DE60039727D1 (de) 2008-09-11
CN1379769A (zh) 2002-11-13
RU2695274C3 (ru) 2020-11-09
NO20021736D0 (no) 2002-04-12
BRPI0014869B8 (pt) 2021-05-25
RU2002112984A (ru) 2004-01-20
JP2009235079A (ja) 2009-10-15
HUP0203746A2 (hu) 2003-03-28
NZ518020A (en) 2004-02-27
PT1220849E (pt) 2004-10-29
US7417067B2 (en) 2008-08-26
BRPI0014869B1 (pt) 2017-06-13
ES2309410T3 (es) 2008-12-16
ES2309410T5 (es) 2015-03-17
AU2004242503A1 (en) 2005-01-27
AR109354A2 (es) 2018-11-21
AR089848A2 (es) 2014-09-24
US20040235885A1 (en) 2004-11-25
EP1220849A2 (en) 2002-07-10
HK1066792A1 (en) 2005-04-01
HU229547B1 (en) 2014-01-28
CZ20021037A3 (cs) 2002-09-11
RU2695274C2 (ru) 2019-07-22
WO2001027099A2 (en) 2001-04-19
KR20020068521A (ko) 2002-08-27
DE60010913D1 (de) 2004-06-24
JP2003511445A (ja) 2003-03-25
DK1426361T3 (da) 2008-11-17
MXPA02003756A (es) 2005-09-08
ES2221859T3 (es) 2005-01-16
ATE402925T2 (de) 2008-08-15
US20080255227A1 (en) 2008-10-16
US8088934B2 (en) 2012-01-03
NO20021736L (no) 2002-04-12
US20120095090A1 (en) 2012-04-19
AR026046A1 (es) 2002-12-26

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