BR0114623A - Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas - Google Patents
Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticasInfo
- Publication number
- BR0114623A BR0114623A BR0114623-8A BR0114623A BR0114623A BR 0114623 A BR0114623 A BR 0114623A BR 0114623 A BR0114623 A BR 0114623A BR 0114623 A BR0114623 A BR 0114623A
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- methods
- treating
- syndrome
- septicemia
- Prior art date
Links
- 208000032928 Dyslipidaemia Diseases 0.000 title abstract 5
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 3
- 206010020772 Hypertension Diseases 0.000 title abstract 3
- 208000017170 Lipid metabolism disease Diseases 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 206010033645 Pancreatitis Diseases 0.000 title abstract 3
- 206010040047 Sepsis Diseases 0.000 title abstract 3
- 201000001881 impotence Diseases 0.000 title abstract 3
- 230000004054 inflammatory process Effects 0.000 title abstract 3
- 208000017169 kidney disease Diseases 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 208000013223 septicemia Diseases 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 208000008839 Kidney Neoplasms Diseases 0.000 title abstract 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title abstract 2
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title abstract 2
- 206010038389 Renal cancer Diseases 0.000 title abstract 2
- 208000018914 glucose metabolism disease Diseases 0.000 title abstract 2
- 201000010982 kidney cancer Diseases 0.000 title abstract 2
- 201000008383 nephritis Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- 235000013594 poultry meat Nutrition 0.000 title 2
- 208000001145 Metabolic Syndrome Diseases 0.000 title 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title 1
- 235000013601 eggs Nutrition 0.000 title 1
- 244000144977 poultry Species 0.000 title 1
- 230000001732 thrombotic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 150000003462 sulfoxides Chemical class 0.000 abstract 2
- 241000272525 Anas platyrhynchos Species 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000003529 anticholesteremic agent Substances 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- -1 ether compound Chemical class 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- 229940126904 hypoglycaemic agent Drugs 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 229940075461 other therapeutic product in atc Drugs 0.000 abstract 1
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- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODOS PARA TRATAR OU PREVENIR UMA DOENçA CARDIOVASCULAR, UMA DISLIPIDEMIA, UMA DISLIPOPROTEINEMIA, UM DISTúRBIO DO METABOLISMO DA GLICOSE, TROMBóTICO E ASSOCIADO COM O RECEPTOR ATIVADO DO PROLIFERADOR DE PEROXISSOMA, A DOENçA DE ALZHEIMER, A SìNDROME X OU SìNDROME METABóLICA, A SEPTICEMIA, A OBESIDADE, PANCREATITE, A HIPERTENSãO, DOENçA RENAL, CâNCER, A INFLAMAçãO E A IMPOTêNCIA, EM UM PACIENTE E PARA REDUZIR O TEOR DE GORDURA DA CARNE EM ANIMAL DE CRIAçãO E DE COLESTEROL DE OVOS DE AVES DOMéSTICAS". A presente invenção diz respeito a novos compostos de sulfóxido e bis-sulfóxido, às composições que compreendem os compostos de sulfóxido e bis-sulfóxido, e aos métodos úteis para tratar e prevenir doenças cardiovasculares, dislipidemias, disproteinemias e distúrbios do metabolismo da glicose que compreendem administrar uma composição que compreenda um composto de éter. Os compostos, composições e métodos da invenção também são úteis para tratar e prevenir a Doença de Alzheimer, a Síndrome X, distúrbios relacionados com o receptor ativado do proliferador de peroxissoma, septicemia, distúrbios trombóticos, obesidade, pancreatite, hipertensão, doença renal, câncer, inflamação e impotência. Em certas formas de realização, os compostos, composições e métodos da invenção são úteis na terapia de combinação com outros produtos terapêuticos, tais como agentes hipocolesterolêmicos e hipoglicêmicos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23910500P | 2000-10-11 | 2000-10-11 | |
PCT/US2001/031871 WO2002030882A2 (en) | 2000-10-11 | 2001-10-11 | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
Publications (1)
Publication Number | Publication Date |
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BR0114623A true BR0114623A (pt) | 2005-12-13 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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BR0114623-8A BR0114623A (pt) | 2000-10-11 | 2001-10-11 | Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas |
Country Status (10)
Country | Link |
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US (1) | US6673780B2 (pt) |
EP (1) | EP1366024A2 (pt) |
JP (1) | JP2004531459A (pt) |
CN (1) | CN1479721A (pt) |
AU (1) | AU2002211667A1 (pt) |
BR (1) | BR0114623A (pt) |
CA (1) | CA2425678A1 (pt) |
IL (1) | IL155246A0 (pt) |
MX (1) | MXPA03003024A (pt) |
WO (1) | WO2002030882A2 (pt) |
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2001
- 2001-10-11 US US09/976,899 patent/US6673780B2/en not_active Expired - Fee Related
- 2001-10-11 EP EP01979735A patent/EP1366024A2/en not_active Withdrawn
- 2001-10-11 AU AU2002211667A patent/AU2002211667A1/en not_active Abandoned
- 2001-10-11 BR BR0114623-8A patent/BR0114623A/pt not_active IP Right Cessation
- 2001-10-11 MX MXPA03003024A patent/MXPA03003024A/es unknown
- 2001-10-11 CN CNA018202683A patent/CN1479721A/zh active Pending
- 2001-10-11 IL IL15524601A patent/IL155246A0/xx unknown
- 2001-10-11 JP JP2002534270A patent/JP2004531459A/ja not_active Withdrawn
- 2001-10-11 CA CA002425678A patent/CA2425678A1/en not_active Abandoned
- 2001-10-11 WO PCT/US2001/031871 patent/WO2002030882A2/en not_active Application Discontinuation
Also Published As
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US6673780B2 (en) | 2004-01-06 |
WO2002030882A2 (en) | 2002-04-18 |
MXPA03003024A (es) | 2003-07-14 |
EP1366024A2 (en) | 2003-12-03 |
JP2004531459A (ja) | 2004-10-14 |
CN1479721A (zh) | 2004-03-03 |
AU2002211667A1 (en) | 2002-04-22 |
CA2425678A1 (en) | 2002-04-18 |
IL155246A0 (en) | 2003-11-23 |
WO2002030882A3 (en) | 2003-09-25 |
WO2002030882A9 (en) | 2003-02-20 |
US20030022865A1 (en) | 2003-01-30 |
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