BR0114617A - Composto, composição farmacêutica, métodos para tratar ou previnir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas - Google Patents
Composto, composição farmacêutica, métodos para tratar ou previnir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticasInfo
- Publication number
- BR0114617A BR0114617A BR0114617-3A BR0114617A BR0114617A BR 0114617 A BR0114617 A BR 0114617A BR 0114617 A BR0114617 A BR 0114617A BR 0114617 A BR0114617 A BR 0114617A
- Authority
- BR
- Brazil
- Prior art keywords
- disease
- methods
- syndrome
- septicemia
- impotence
- Prior art date
Links
- 208000032928 Dyslipidaemia Diseases 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 5
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 3
- 206010020772 Hypertension Diseases 0.000 title abstract 3
- 208000008839 Kidney Neoplasms Diseases 0.000 title abstract 3
- 208000017170 Lipid metabolism disease Diseases 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 206010033645 Pancreatitis Diseases 0.000 title abstract 3
- 206010038389 Renal cancer Diseases 0.000 title abstract 3
- 206010040047 Sepsis Diseases 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 201000001881 impotence Diseases 0.000 title abstract 3
- 230000004054 inflammatory process Effects 0.000 title abstract 3
- 201000010982 kidney cancer Diseases 0.000 title abstract 3
- 208000017169 kidney disease Diseases 0.000 title abstract 3
- 201000008383 nephritis Diseases 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 208000013223 septicemia Diseases 0.000 title abstract 3
- 208000024827 Alzheimer disease Diseases 0.000 title abstract 2
- 102000003728 Peroxisome Proliferator-Activated Receptors Human genes 0.000 title abstract 2
- 108090000029 Peroxisome Proliferator-Activated Receptors Proteins 0.000 title abstract 2
- 208000018914 glucose metabolism disease Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000011580 syndromic disease Diseases 0.000 title abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 2
- 208000001145 Metabolic Syndrome Diseases 0.000 title 1
- 241001465754 Metazoa Species 0.000 title 1
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title 1
- 235000012000 cholesterol Nutrition 0.000 title 1
- 235000013601 eggs Nutrition 0.000 title 1
- 235000013372 meat Nutrition 0.000 title 1
- 244000144977 poultry Species 0.000 title 1
- 230000001732 thrombotic effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 150000002170 ethers Chemical class 0.000 abstract 2
- 241000272525 Anas platyrhynchos Species 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 239000003529 anticholesteremic agent Substances 0.000 abstract 1
- 239000003472 antidiabetic agent Substances 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- -1 ether compound Chemical class 0.000 abstract 1
- 230000000871 hypocholesterolemic effect Effects 0.000 abstract 1
- 229940126904 hypoglycaemic agent Drugs 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 229940075461 other therapeutic product in atc Drugs 0.000 abstract 1
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- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
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- C07F9/06—Phosphorus compounds without P—C bonds
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Abstract
"COMPOSTO, COMPOSIçãO FARMACêUTICA, MéTODOS PARA TRATAR OU PREVENIR UMA DOENçA CARDIOVASCULAR, UMA DISLIPIDEMIA, UMA DISLIPOPROTEINEMIA, UM DISTúRBIO DO METABOLISMO DA GLICOSE, TROMBóTICO E ASSOCIADO COM O RECEPTOR ATIVADO DO PROLIFERADOR DE PEROXISSOMA, A DOENçA DE ALZHEIMER, A SìNDROME X OU SìNDROME METABóLICA, A SEPTICEMIA, A OBESIDADE, PANCREATITE, A HIPERTENSãO, DOENçA RENAL, CâNCER, A INFLAMAçãO E A IMPOTêNCIA, EM UM PACIENTE E PARA REDUZIR O TEOR DE GORDURA DA CARNE EM ANIMAL DE CRIAçãO E DE COLESTEROL DE OVOS DE AVES DOMéSTICAS". A presente invenção diz respeito a novos compostos de éter, composições que compreendem os compostos de éter e métodos úteis para tratar e prevenir doenças cardiovasculares, dislipidemias, disproteinemias e distúrbios do metabolismo da glicose que compreendem administrar uma composição que compreenda um composto de éter. Os compostos, composições e métodos da invenção também são úteis para tratar e prevenir a doença de Alzheimer, síndrome X, distúrbios relacionados com o receptor ativado do proliferador de peroxissoma, septicemia, distúrbios trombóticos, obesidade, pancreatite, hipertensão, doença renal, câncer, inflamação e impotência. Em certas formas de realização, os compostos, composições e métodos da invenção são úteis na terapia de combinação com outros produtos terapêuticos tais como agentes hipocolesterolêmicos e hipoglicêmicos.
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US (1) | US6713507B2 (pt) |
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IL155215A0 (en) | 2003-11-23 |
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CA2425121A1 (en) | 2002-04-18 |
MXPA03003021A (es) | 2003-07-14 |
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CN1894195A (zh) | 2007-01-10 |
US20030018013A1 (en) | 2003-01-23 |
EP1351916A2 (en) | 2003-10-15 |
WO2002030863A3 (en) | 2003-07-31 |
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