BR0112295A - Método para a fabricação de um artigo moldado tendo um núcleo, dispositivo para a fabricação de um artigo moldado tendo um núcleo, artigo moldado e agregado de artigos moldados - Google Patents

Método para a fabricação de um artigo moldado tendo um núcleo, dispositivo para a fabricação de um artigo moldado tendo um núcleo, artigo moldado e agregado de artigos moldados

Info

Publication number
BR0112295A
BR0112295A BR0112295-9A BR0112295A BR0112295A BR 0112295 A BR0112295 A BR 0112295A BR 0112295 A BR0112295 A BR 0112295A BR 0112295 A BR0112295 A BR 0112295A
Authority
BR
Brazil
Prior art keywords
molded article
core
manufacturing
molding material
puncture member
Prior art date
Application number
BR0112295-9A
Other languages
English (en)
Other versions
BR0112295B1 (pt
Inventor
Yoshiya Kondo
Yukinao Watanabe
Yuichi Ozeki
Original Assignee
Sanwa Kagaku Kenkyusho Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanwa Kagaku Kenkyusho Co filed Critical Sanwa Kagaku Kenkyusho Co
Priority claimed from US10/317,360 external-priority patent/US7811488B2/en
Publication of BR0112295A publication Critical patent/BR0112295A/pt
Publication of BR0112295B1 publication Critical patent/BR0112295B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/02—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space
    • B30B11/08—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using a ram exerting pressure on the material in a moulding space co-operating with moulds carried by a turntable
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Mechanical Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Casting Or Compression Moulding Of Plastics Or The Like (AREA)
  • Press-Shaping Or Shaping Using Conveyers (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)

Abstract

"MéTODO PARA A FABRICAçãO DE UM ARTIGO MOLDADO TENDO UM NúCLEO, DISPOSITIVO PARA A FABRICAçãO DE UM ARTIGO MOLDADO TENDO UM NúCLEO, ARTIGO MOLDADO E AGREGADO DE ARTIGOS MOLDADOS". A presente invenção se refere à fabricação, de uma forma eficiente, de um artigo moldado tendo um núcleo e, ao mesmo tempo, a partir de um material de moldagem tal como um grânulo em pó. Com esta finalidade, um método para a fabricação do artigo moldado tendo um núcleo foi desenvolvido, cujo método utiliza um dispositivo de moldagem por compressão, o qual compreende uma matriz de moldagem, membros de punção superior e inferior, onde pelo menos o membro de punção superior, preferivelmente ambos os membros de punção superior e inferior, têm uma construção dupla consistindo de um membro de punção central e um membro de punção externo circundando a periferia externa do membro de punção central, ambos o membro de punção central e o membro de punção externo sendo capazes de desempenhar movimentos de deslocamento bem como operações de compressão. Este método inclui etapas de alimentação separada do material de moldagem para o núcleo e do material de moldagem para a camada externa, uma etapa de moldagem por compressão do material de moldagem para o núcleo e/ou do material de moldagem para a camada externa, e uma etapa de moldagem por compressão final do artigo moldado tendo um núcleo. A invenção também proporciona uma máquina rotativa para a moldagem por compressão, usada para a execução do método. A invenção também proporciona várias características para um artigo moldado tendo um núcleo fabricados pelo método de fabricação acima mencionado. O núcleo pode incluir uma grande quantidade de microcápsulas que são moldes incompletos, ou uma pluralidade de núcleos.
BRPI0112295-9A 2000-06-20 2001-06-20 mÉtodo para a fabricaÇço de um artigo moldado tendo um nécleo, dispositivo para a fabricaÇço de um artigo moldado tendo um nécleo, artigo moldado e agregado de artigos moldados. BR0112295B1 (pt)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP2000183996 2000-06-20
JP2000387052 2000-12-20
JP2001042787 2001-02-20
JP2001074413 2001-03-15
JP2001098571 2001-03-30
JP2001125690 2001-04-24
PCT/JP2001/005296 WO2001098067A1 (fr) 2000-06-20 2001-06-20 Article moule a noyau, procede de production de cet article et dispositif permettant de le produire
US10/317,360 US7811488B2 (en) 2000-06-20 2002-12-12 Method for manufacturing molded article with core

Publications (2)

Publication Number Publication Date
BR0112295A true BR0112295A (pt) 2003-09-02
BR0112295B1 BR0112295B1 (pt) 2011-06-14

Family

ID=32966894

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0112295-9A BR0112295B1 (pt) 2000-06-20 2001-06-20 mÉtodo para a fabricaÇço de um artigo moldado tendo um nécleo, dispositivo para a fabricaÇço de um artigo moldado tendo um nécleo, artigo moldado e agregado de artigos moldados.

Country Status (6)

Country Link
EP (1) EP1302304B1 (pt)
CN (1) CN1315638C (pt)
AU (1) AU2001274575A1 (pt)
BR (1) BR0112295B1 (pt)
CA (1) CA2412173C (pt)
WO (1) WO2001098067A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100463775B1 (ko) * 2000-12-04 2004-12-29 가부시키가이샤 무라타 세이사쿠쇼 분말 공급 장치 및 분말 성형 장치
KR20030096365A (ko) 2001-05-07 2003-12-24 가부시키가이샤 기쿠수이세이사쿠쇼 회전식 압축 성형기
EP1698448B1 (en) * 2003-11-14 2017-01-18 Sanwa Kagaku Kenkyusho Co., Ltd. Method of manufacturing nucleated molding
WO2005097041A1 (ja) * 2004-04-09 2005-10-20 Sanwa Kagaku Kenkyusho Co., Ltd. 有核成型品とその製造方法
KR101172926B1 (ko) * 2004-08-26 2012-08-10 가부시키가이샤산와카가쿠켄큐쇼 공이 및 그것을 이용한 회전식 압축 성형기
CN101291656B (zh) 2005-08-18 2012-11-07 帝人制药株式会社 具有准确的用量分割功能的制剂
GB0702974D0 (en) * 2007-02-15 2007-03-28 Jagotec Ag Method and apparatus for producing a tablet
KR20120034643A (ko) * 2009-05-20 2012-04-12 다이닛본 스미토모 세이야꾸 가부시끼가이샤 유핵형 구강 내 붕괴 정
CN102740893B (zh) * 2009-12-11 2014-07-23 大日本住友制药株式会社 压制包衣的口腔崩解片剂
EP2764989A4 (en) * 2011-10-04 2016-01-20 Sanwa Kagaku Kenkyusho Co POWDER FILLING DEVICE WITH COLLECTING MECHANISM OF EXCESSIVE POWDER AND TURNING PRESSING MACHINE
US20150093488A1 (en) * 2012-03-12 2015-04-02 Nienstedt Gmbh Device for forming portions of food in multiple receptacles
US20160136091A1 (en) 2013-07-19 2016-05-19 Sanwa Kagaku Kenkyusho Co., Ltd. Orally Disintegrating Tablet
EP3043779B1 (en) * 2013-09-13 2018-05-16 R.P. Scherer Technologies, LLC Encased-pellet tablets
US10064827B2 (en) 2013-12-11 2018-09-04 Roland SAUR-BROSCH Method for the production of a molding
CN104589691B (zh) * 2014-12-22 2016-04-06 泉州众志金刚石工具有限公司 一种金刚石刀头的自动流水线装坯机
DE102015105936B4 (de) * 2015-04-17 2017-07-13 Fette Compacting Gmbh Rotor für eine Rundläuferpresse
TWI690333B (zh) * 2015-06-29 2020-04-11 日商大賽璐股份有限公司 易服用性固態製劑（有核錠）之製造方法及易服用性固態製劑
CN109435315B (zh) * 2018-11-09 2023-06-23 苏州益顺华智能装备有限公司 一种全自动胶饼机
TWI698237B (zh) * 2018-11-22 2020-07-11 陳慧如 多層錠膠體複合成錠方法及製品
CN114425879A (zh) * 2020-10-28 2022-05-03 上海复星星泰医药科技有限公司 一种用于制备包芯片的压片机、包芯片及其制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB743222A (en) * 1953-05-27 1956-01-11 Thomas Kerfoot & Co Ltd Improvements in the formation of compressed tablets
GB839502A (en) * 1957-01-09 1960-06-29 Kilian And Company G M B H Method of and apparatus for manufacturing coated tablets
DE1210513B (de) * 1962-03-22 1966-02-10 Wilhelm Fette Praez Swerkzeug Verfahren zum Pressen oben offener Huellen aus Huellmasse fuer das Herstellen von Tabletten
JPS52126577A (en) 1976-04-16 1977-10-24 Kikusui Seisakusho Ltd Lower pounder device in rotary type powder compression forming machine
GB1598458A (en) 1977-04-01 1981-09-23 Hoechst Uk Ltd Tableting of microcapsules
JPS5548653A (en) 1978-10-03 1980-04-07 Kikusui Seisakusho:Kk Nucleus centering test method for rotary nucleated tablet machine
JPS5939499A (ja) * 1982-08-28 1984-03-03 Tokyo Shiyouketsu Kinzoku Kk 圧粉体の成形方法
JPS6160298A (ja) 1984-08-30 1986-03-27 Kikusui Seisakusho:Kk 回転式有核錠剤機の核錠供給位置自動調節装置
US4710384A (en) 1986-07-28 1987-12-01 Avner Rotman Sustained release tablets made from microcapsules
JPH0726074Y2 (ja) * 1989-03-16 1995-06-14 株式会社菊水製作所 ダブル有核錠剤の製造装置
JPH02243158A (ja) 1989-03-16 1990-09-27 Kikusui Seisakusho:Kk ダブル有核錠剤及びその製造方法
US5071607A (en) * 1990-01-31 1991-12-10 Alza Corporatino Method and apparatus for forming a hole in a drug dispensing device
JPH0536619A (ja) 1991-07-25 1993-02-12 Canon Inc 半導体表面処理方法及び装置
JP2838477B2 (ja) * 1994-02-04 1998-12-16 株式会社ヨシツカ精機 段付成形品の粉末成形方法および装置
JPH0952847A (ja) * 1995-08-10 1997-02-25 Sando Yakuhin Kk 徐放性製剤
JP2802054B2 (ja) * 1996-02-06 1998-09-21 株式会社菊水製作所 回転式有核錠剤機
JP2931303B1 (ja) * 1998-08-25 1999-08-09 株式会社菊水製作所 回転式有核錠剤機

Also Published As

Publication number Publication date
AU2001274575A1 (en) 2002-01-02
CN1315638C (zh) 2007-05-16
EP1302304A1 (en) 2003-04-16
EP1302304B1 (en) 2011-12-14
CA2412173C (en) 2010-08-17
WO2001098067A1 (fr) 2001-12-27
BR0112295B1 (pt) 2011-06-14
CN1437531A (zh) 2003-08-20
EP1302304A4 (en) 2005-12-28
CA2412173A1 (en) 2002-12-06

Similar Documents

Publication Publication Date Title
BR0112295A (pt) Método para a fabricação de um artigo moldado tendo um núcleo, dispositivo para a fabricação de um artigo moldado tendo um núcleo, artigo moldado e agregado de artigos moldados
SE9903011D0 (sv) Sätt att framställa en plastprodukt och ett härför utnyttjat plastproduktformande arrangemang
BRPI0411548A (pt) stent polimérico e método de fabricação
WO2007029845A3 (en) Method and device for manufacturing structure having pattern, and method for manufacturing mold
ATE287223T1 (de) Schuhsohlenanordnung
WO2003095708A3 (en) Methods of and apparatus for molding structures
WO2009135521A3 (de) Fasern zur verwendung bei der herstellung eines schichtweise aufgebauten formkörpers
EP1052075A3 (en) Mold and molding machine for making ophthalmic devices
WO2007090904A8 (es) Aparato y procedimiento para fabricación de cuerpos huecos bimaterial por sobremoldeo de inyección
DE602006005491D1 (de) Kerne und mikrokapseln für die parenterale verabreichung und herstellungsverfahren dafür
MX2009004253A (es) Herramienta compuesta para el moldeado de piezas cilindricas.
DE602005021167D1 (de) Identifikationseinrichtung sowie Verfahren zu deren Herstellung
FI20031634A0 (fi) Menetelmä ruiskuvalettujen muovituotteiden valmistamiseksi sekä integroitu jatkojalostusmenetelmä
HUE031024T2 (en) A method for producing masonry units and a method for producing masonry units
FR2888852B1 (fr) Matiere a mouler et son procede de production
WO2008054319A3 (en) Device at collapsible core, preferably at injection moulding tool for plastic material, silicone, rubber and similar material
MXPA02012640A (es) Piezas moldeadas que tienen nucleo y metodos y aparato para fabricarlas.
DE60234844D1 (de) Wärmesschrumpfbare harzfilmrolle auf polystyrolbasis und herstellungsverfahren dafür sowie wärmeschrumpfbares etikett
BR0317756A (pt) Método para formação de artigos de material sintético, e, instalação para a formação de artigos de componentes múltiplos ou de componente único de grande espessura de material sintético
KR20050026092A (ko) 다층 플라스틱 제품 사출 성형 방법 및 그 다층 플라스틱제품
PL1658395T3 (pl) Sposób wytwarzania wytworów formowanych o właściwościach termoregulacyjnych
FR2804364B1 (fr) Procede de fabrication d'une piece en matiere plastique comportant un film decoratif, et piece ainsi obtenue
FR2860445B1 (fr) Procede de fabrication d'un moule et moule obtenu.
BRPI0418713A (pt) máquina para moldagem de painéis de concreto sobre uma base alongada de moldagem e molde segmentado de concreto
DK1372933T3 (da) Fremgangsmåde til fremstilling af en formdel i et formværktöj

Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 20/06/2001, OBSERVADAS AS CONDICOES LEGAIS.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 20A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2624 DE 20-04-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.