BR0111188A - Inibidores de adesão de célula mediada por alfal beta2 - Google Patents
Inibidores de adesão de célula mediada por alfal beta2Info
- Publication number
- BR0111188A BR0111188A BR0111188-4A BR0111188A BR0111188A BR 0111188 A BR0111188 A BR 0111188A BR 0111188 A BR0111188 A BR 0111188A BR 0111188 A BR0111188 A BR 0111188A
- Authority
- BR
- Brazil
- Prior art keywords
- cell adhesion
- mediated cell
- adhesion inhibitors
- beta
- alpha2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Abstract
"INIBIDORES DE ADESãO DE CéLULA MEDIADA POR ALFA~ L~BETA~ 2~". A presente invenção refere-se a pequenas moléculas de acordo com a fórmula (I) que são potentes inibidores de adesão de célula mediada por <244>~ L~<225>~ 2~ e que podem ser úteis para o tratamento de doenças inflamatórias.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20796800P | 2000-05-31 | 2000-05-31 | |
PCT/US2001/012323 WO2001092253A2 (en) | 2000-05-31 | 2001-04-17 | Inhibitors of alpha l beta 2 mediated cell adhesion |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0111188A true BR0111188A (pt) | 2003-06-10 |
Family
ID=22772705
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0111188-4A BR0111188A (pt) | 2000-05-31 | 2001-04-17 | Inibidores de adesão de célula mediada por alfal beta2 |
Country Status (19)
Country | Link |
---|---|
US (1) | US6699888B2 (pt) |
EP (1) | EP1284973B1 (pt) |
JP (1) | JP3924531B2 (pt) |
KR (1) | KR100527290B1 (pt) |
CN (1) | CN1209358C (pt) |
AT (1) | ATE365729T1 (pt) |
AU (2) | AU2001253538B2 (pt) |
BR (1) | BR0111188A (pt) |
CA (1) | CA2411671C (pt) |
CY (1) | CY1106843T1 (pt) |
DE (1) | DE60129132T2 (pt) |
DK (1) | DK1284973T3 (pt) |
ES (1) | ES2284641T3 (pt) |
HK (1) | HK1051370A1 (pt) |
IL (1) | IL152961A0 (pt) |
MX (1) | MXPA02011858A (pt) |
NZ (1) | NZ522852A (pt) |
PT (1) | PT1284973E (pt) |
WO (1) | WO2001092253A2 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004007444A2 (en) | 2002-07-11 | 2004-01-22 | Vicuron Pharmaceuticals, Inc. | N-hydroxyamide derivatives possessing antibacterial activity |
FR2850652B1 (fr) * | 2003-01-31 | 2008-05-30 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
US7354933B2 (en) | 2003-01-31 | 2008-04-08 | Aventis Pharma Sa | Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors |
WO2006082834A1 (ja) * | 2005-02-02 | 2006-08-10 | Kowa Co., Ltd. | ケラチノサイト増殖に起因する疾患の予防・治療剤 |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
AU2012241184B2 (en) * | 2006-03-27 | 2016-01-07 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
AU2013205325B2 (en) * | 2006-03-27 | 2016-03-24 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
AU2016201061B2 (en) * | 2006-03-27 | 2017-03-02 | The Regents Of The University Of California | Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases |
DK2368550T3 (da) | 2006-03-27 | 2013-09-30 | Univ California | Androgenreceptormodulator til behandlingen af prostatakræft og androgenreceptor-associerede sygdomme |
EP2439196A1 (en) | 2006-03-29 | 2012-04-11 | The Regents of The University of California | Diarylthiohydantoin compounds for use in a method for the treatment of a hyperproliferative disorder |
UY31432A1 (es) * | 2007-10-26 | 2009-05-29 | Compuestos de diarilhidantoina | |
MX2011011964A (es) | 2009-05-12 | 2012-02-23 | Janssen Pharmaceuticals Inc | Derivados de 1,2,3-triazolo[4,3-a]piridina y su uso para el tratamiento o prevencion de trastornos neurologicos y psiquiatricos. |
SG10201501202TA (en) | 2010-02-16 | 2015-04-29 | Aragon Pharmaceuticals Inc | Androgen Receptor Modulators And Uses Thereof |
US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
ES2836424T3 (es) | 2012-09-26 | 2021-06-25 | Aragon Pharmaceuticals Inc | Antiandrógenos para tratar el cáncer de próstata no metastásico y resistente a la castración |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
EP3697398A1 (en) | 2017-10-16 | 2020-08-26 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0091596B1 (de) | 1982-04-08 | 1991-09-11 | Shell Internationale Researchmaatschappij B.V. | Neue Hydantoine, ihre Herstellung und Verwendung |
DE19540027A1 (de) * | 1995-10-27 | 1997-04-30 | Gruenenthal Gmbh | Substituierte Imidazolidin-2,4-dion-Verbindungen als pharmazeutische Wirkstoffe |
US6350763B1 (en) * | 1999-07-21 | 2002-02-26 | Boehringer Ingelheim Pharmaceuticals, Inc. | Small molecules useful in the treatment of inflammation disease |
-
2001
- 2001-04-17 WO PCT/US2001/012323 patent/WO2001092253A2/en active IP Right Grant
- 2001-04-17 US US10/296,907 patent/US6699888B2/en not_active Expired - Fee Related
- 2001-04-17 ES ES01927050T patent/ES2284641T3/es not_active Expired - Lifetime
- 2001-04-17 DE DE60129132T patent/DE60129132T2/de not_active Expired - Fee Related
- 2001-04-17 BR BR0111188-4A patent/BR0111188A/pt not_active IP Right Cessation
- 2001-04-17 IL IL15296101A patent/IL152961A0/xx unknown
- 2001-04-17 AU AU2001253538A patent/AU2001253538B2/en not_active Ceased
- 2001-04-17 JP JP2002500866A patent/JP3924531B2/ja not_active Expired - Fee Related
- 2001-04-17 NZ NZ522852A patent/NZ522852A/en unknown
- 2001-04-17 MX MXPA02011858A patent/MXPA02011858A/es active IP Right Grant
- 2001-04-17 AT AT01927050T patent/ATE365729T1/de not_active IP Right Cessation
- 2001-04-17 CN CNB018104630A patent/CN1209358C/zh not_active Expired - Fee Related
- 2001-04-17 PT PT01927050T patent/PT1284973E/pt unknown
- 2001-04-17 AU AU5353801A patent/AU5353801A/xx active Pending
- 2001-04-17 EP EP01927050A patent/EP1284973B1/en not_active Expired - Lifetime
- 2001-04-17 DK DK01927050T patent/DK1284973T3/da active
- 2001-04-17 CA CA002411671A patent/CA2411671C/en not_active Expired - Fee Related
- 2001-04-17 KR KR10-2002-7014945A patent/KR100527290B1/ko not_active IP Right Cessation
-
2003
- 2003-05-23 HK HK03103658A patent/HK1051370A1/xx not_active IP Right Cessation
-
2007
- 2007-09-04 CY CY20071101143T patent/CY1106843T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1209358C (zh) | 2005-07-06 |
WO2001092253A3 (en) | 2002-05-23 |
HK1051370A1 (en) | 2003-08-01 |
CN1432007A (zh) | 2003-07-23 |
ES2284641T3 (es) | 2007-11-16 |
DK1284973T3 (da) | 2007-10-08 |
CA2411671A1 (en) | 2001-12-06 |
JP2003535087A (ja) | 2003-11-25 |
AU2001253538B2 (en) | 2004-03-04 |
KR20030015235A (ko) | 2003-02-20 |
MXPA02011858A (es) | 2004-07-30 |
CY1106843T1 (el) | 2012-05-23 |
CA2411671C (en) | 2007-06-05 |
ATE365729T1 (de) | 2007-07-15 |
JP3924531B2 (ja) | 2007-06-06 |
DE60129132D1 (de) | 2007-08-09 |
PT1284973E (pt) | 2007-08-17 |
DE60129132T2 (de) | 2008-02-28 |
NZ522852A (en) | 2004-09-24 |
EP1284973A2 (en) | 2003-02-26 |
EP1284973B1 (en) | 2007-06-27 |
AU5353801A (en) | 2001-12-11 |
KR100527290B1 (ko) | 2005-11-09 |
IL152961A0 (en) | 2003-06-24 |
US6699888B2 (en) | 2004-03-02 |
WO2001092253A2 (en) | 2001-12-06 |
US20030225138A1 (en) | 2003-12-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: MITSUBISHI TANABE PHARMA CORPORATION (JP) Free format text: ALTERADO DE: TANABE SEIYAKU CO., LTD. |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A E 10A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2138 DE 27/12/2011. |