BR0108659A - Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo - Google Patents
Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpoInfo
- Publication number
- BR0108659A BR0108659A BR0108659-6A BR0108659A BR0108659A BR 0108659 A BR0108659 A BR 0108659A BR 0108659 A BR0108659 A BR 0108659A BR 0108659 A BR0108659 A BR 0108659A
- Authority
- BR
- Brazil
- Prior art keywords
- breast cancer
- bcmps
- antibody
- composition
- treatment
- Prior art date
Links
- 206010006187 Breast cancer Diseases 0.000 title abstract 9
- 208000026310 Breast neoplasm Diseases 0.000 title abstract 9
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000011282 treatment Methods 0.000 title abstract 5
- 238000003745 diagnosis Methods 0.000 title abstract 3
- 238000011156 evaluation Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 238000012544 monitoring process Methods 0.000 title abstract 3
- 238000004393 prognosis Methods 0.000 title abstract 3
- 206010055113 Breast cancer metastatic Diseases 0.000 title abstract 2
- 239000012472 biological sample Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000001514 detection method Methods 0.000 title abstract 2
- 230000000694 effects Effects 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 238000011321 prophylaxis Methods 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 210000000481 breast Anatomy 0.000 title 1
- 238000009509 drug development Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1045—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants
- A61K51/1051—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against animal or human tumor cells or tumor cell determinants the tumor cell being from breast, e.g. the antibody being herceptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57419—Specifically defined cancers of colon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Hospice & Palliative Care (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Optics & Photonics (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
Abstract
"MéTODOS PARA TRATAMENTO OU PREVENçãO OU PROFILAXIA DE CâNCER DE MAMA, PARA DETECçãO, DIAGNóSTICO E/OU AVALIAçãO OU PROGNóSTICO QUANTO AO CâNCER DE MAMA, PARA MONITORAçãO E/OU ESTIMATIVA DE TRATAMENTO DO CâNCER DE MAMA, PARA IDENTIFICAçãO DA PRESENçA OU AUSêNCIA DE CéLULAS DE CâNCER DE MAMA METASTáTICAS EM UM AMOSTRA BIOLóGICA E PARA AVALIAçãO OU IDENTIFICAçãO DE COMPOSTOS, USOS DE UMA OU MAIS BCMPS, DE UMA COMPOSIçãO, DE UM ANTICORPO, DE áCIDO NUCLEICO E DE UM AGENTE QUE INTERAJA COM OU MODULE A ATIVIDADE DE UMA OU MAIS BCMPS, VACINA, COMPOSIçãO, KIT E ANTICORPO". A presente invenção fornece métodos e composições para a avaliação, diagnóstico e prognóstico de câncer de mama, para monitorar a eficácia de tratamento do câncer de mama e para o desenvolvimento de medicamento.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0004576.5A GB0004576D0 (en) | 2000-02-25 | 2000-02-25 | Proteins |
GB0031341A GB0031341D0 (en) | 2000-12-21 | 2000-12-21 | Protein |
PCT/GB2001/000748 WO2001062784A2 (en) | 2000-02-25 | 2001-02-21 | Use of breast cancer associated membrane proteins (bcmp) for treatment, prophylaxis and diagnosis of breast cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0108659A true BR0108659A (pt) | 2002-11-05 |
Family
ID=26243736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0108659-6A BR0108659A (pt) | 2000-02-25 | 2001-02-21 | Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo |
Country Status (15)
Country | Link |
---|---|
US (3) | US20030130214A1 (pt) |
EP (2) | EP1259604A1 (pt) |
JP (1) | JP2003524017A (pt) |
KR (1) | KR100740761B1 (pt) |
CN (1) | CN100384875C (pt) |
AT (1) | ATE352311T1 (pt) |
AU (3) | AU2001233929C1 (pt) |
BR (1) | BR0108659A (pt) |
CA (1) | CA2399999A1 (pt) |
DE (1) | DE60126248T2 (pt) |
ES (1) | ES2279801T3 (pt) |
HK (1) | HK1056692A1 (pt) |
IL (1) | IL151448A0 (pt) |
NZ (1) | NZ520967A (pt) |
WO (2) | WO2001062914A1 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7054758B2 (en) * | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
GB0125072D0 (en) * | 2001-10-18 | 2001-12-12 | Oxford Glycosciences Uk Ltd | Protein |
AU2003209459A1 (en) * | 2002-03-06 | 2003-09-16 | Hybrigenics | Protein-protein interactions in human tumours involving bcmp-7 and bcmp-11 |
US20040033530A1 (en) * | 2002-04-08 | 2004-02-19 | Awrey Donald E. | High throughput purification, characterization and identification of recombinant proteins |
GB0208331D0 (en) * | 2002-04-11 | 2002-05-22 | Oxford Glycosciences Uk Ltd | Proteins |
FR2846426B1 (fr) * | 2002-10-28 | 2004-12-10 | Bio Merieux | Procede de dosage du ngf pour le diagnostic in vitro du cancer du sein et utilisation en therapie |
EP1567545B1 (en) * | 2002-12-06 | 2010-05-05 | Zhi Cheng Xiao | Peptides and their use in the treatment of central nervous system damage |
US20080254445A1 (en) * | 2003-09-22 | 2008-10-16 | Kyogo Itoh | Prognosis in Cancer Patients Vaccinated with a Cancer Antigen Peptide-Associated Agent |
EP1693069B1 (en) | 2003-10-10 | 2013-07-24 | Chugai Seiyaku Kabushiki Kaisha | Remedy for solid tumor |
JP2007520217A (ja) * | 2004-01-27 | 2007-07-26 | コンピュゲン ユーエスエイ,インク. | 新規ヌクレオチドおよびアミノ酸配列、ならびにそれを用いた乳癌診断のためのアッセイおよび使用方法 |
KR100763902B1 (ko) * | 2004-02-20 | 2007-10-05 | 삼성전자주식회사 | 유방암 특이적 단백질, 그를 코딩하는 유전자, 및 상기단백질 또는 유전자를 이용한 유방암의 진단 방법 |
WO2008104803A2 (en) * | 2007-02-26 | 2008-09-04 | Oxford Genome Sciences (Uk) Limited | Proteins |
KR101398079B1 (ko) | 2011-10-10 | 2014-05-27 | 재단법인 의약바이오컨버젼스연구단 | 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법 |
CN104447975A (zh) * | 2014-11-18 | 2015-03-25 | 深圳市人口和计划生育科学研究所 | 一种提取人肿瘤细胞膜蛋白的方法 |
WO2017011375A1 (en) * | 2015-07-10 | 2017-01-19 | University Of Iowa Reseaarch Foundation | Bst-2 as a therapeutic target and a predictive/prognostic bio-signature for breast cancer growth and metastasis |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002508652A (ja) * | 1996-08-23 | 2002-03-19 | ヒューマン ジノーム サイエンシーズ,インコーポレイテッド | 新規なヒト増殖因子 |
DE19813839A1 (de) * | 1998-03-20 | 1999-09-23 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Brusttumorgewebe |
PL354093A1 (en) * | 1999-06-30 | 2003-12-29 | Corixa Corporationcorixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
-
2001
- 2001-02-21 ES ES01905965T patent/ES2279801T3/es not_active Expired - Lifetime
- 2001-02-21 AU AU2001233929A patent/AU2001233929C1/en not_active Ceased
- 2001-02-21 CN CNB018084885A patent/CN100384875C/zh not_active Expired - Fee Related
- 2001-02-21 AU AU2001233913A patent/AU2001233913A1/en not_active Abandoned
- 2001-02-21 NZ NZ520967A patent/NZ520967A/en unknown
- 2001-02-21 DE DE60126248T patent/DE60126248T2/de not_active Expired - Fee Related
- 2001-02-21 AU AU3392901A patent/AU3392901A/xx active Pending
- 2001-02-21 WO PCT/GB2001/000729 patent/WO2001062914A1/en not_active Application Discontinuation
- 2001-02-21 EP EP01905949A patent/EP1259604A1/en not_active Withdrawn
- 2001-02-21 AT AT01905965T patent/ATE352311T1/de not_active IP Right Cessation
- 2001-02-21 EP EP01905965A patent/EP1257285B1/en not_active Expired - Lifetime
- 2001-02-21 CA CA002399999A patent/CA2399999A1/en not_active Abandoned
- 2001-02-21 IL IL15144801A patent/IL151448A0/xx unknown
- 2001-02-21 BR BR0108659-6A patent/BR0108659A/pt not_active IP Right Cessation
- 2001-02-21 KR KR1020027011130A patent/KR100740761B1/ko not_active IP Right Cessation
- 2001-02-21 JP JP2001562565A patent/JP2003524017A/ja active Pending
- 2001-02-21 WO PCT/GB2001/000748 patent/WO2001062784A2/en active IP Right Grant
- 2001-02-23 US US09/791,392 patent/US20030130214A1/en not_active Abandoned
-
2002
- 2002-08-23 US US10/227,616 patent/US20030099662A1/en not_active Abandoned
-
2003
- 2003-12-16 HK HK03109173.7A patent/HK1056692A1/xx not_active IP Right Cessation
-
2006
- 2006-08-24 US US11/509,841 patent/US20070212368A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE60126248T2 (de) | 2007-07-05 |
JP2003524017A (ja) | 2003-08-12 |
NZ520967A (en) | 2004-04-30 |
CN100384875C (zh) | 2008-04-30 |
ATE352311T1 (de) | 2007-02-15 |
US20030130214A1 (en) | 2003-07-10 |
AU2001233913A1 (en) | 2001-09-03 |
AU2001233929C1 (en) | 2006-03-02 |
DE60126248D1 (de) | 2007-03-15 |
EP1257285B1 (en) | 2007-01-24 |
US20070212368A1 (en) | 2007-09-13 |
AU3392901A (en) | 2001-09-03 |
WO2001062784A3 (en) | 2002-01-31 |
CA2399999A1 (en) | 2001-08-30 |
KR20030007440A (ko) | 2003-01-23 |
WO2001062784A2 (en) | 2001-08-30 |
IL151448A0 (en) | 2003-04-10 |
EP1259604A1 (en) | 2002-11-27 |
KR100740761B1 (ko) | 2007-07-19 |
AU2001233929B2 (en) | 2005-09-08 |
HK1056692A1 (en) | 2004-02-27 |
CN1426307A (zh) | 2003-06-25 |
EP1257285A2 (en) | 2002-11-20 |
WO2001062914A1 (en) | 2001-08-30 |
ES2279801T3 (es) | 2007-09-01 |
US20030099662A1 (en) | 2003-05-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0108659A (pt) | Métodos para tratamento ou prevenção ou profilaxia de câncer de mama, para detecção, diagnóstico e/ou avaliação ou prognóstico quanto ao câncer de mama, para monitoração e/ou estimativa de tratamento do câncer de mama, para identificação da presença ou ausência de células de câncer de mama metastáticas em um amostra biológica e para avaliação ou identificação de compostos, usos de uma ou mais bcmps, de uma composição, de um anticorpo, de ácido nucleico e de um agente que interaja com ou module a atividade de uma ou mais bcmps, vacina, composição, kit e anticorpo | |
Sonoda et al. | Colorectal cancer screening with odour material by canine scent detection | |
Zhang et al. | Total antioxidant capacity and total oxidant status in saliva of periodontitis patients in relation to bacterial load | |
Dunkel et al. | Reproducibility of microbial mutagenicity assays: II. Testing of carcinogens and noncarcinogens in Salmonella typhimurium and Escherichia coli | |
BR9814821A (pt) | Ensaio de analìtico usando marcas em partìculas | |
BRPI0612169A2 (pt) | métodos prognósticos, métodos de detecção, de distinção, de identificação, de determinação e de monitoramento relacionados com cáncer de pulmão, métodos para amplificação de um ácido nucléico que codifica c-met humano , biomarcadores de cáncer de pulmão, agentes de imagem de cáncer de pulmão, polinucleotìdeos, agente s de ligação de antìgeno, conjuntos, meios legìveis em computador e kits e/ou artigos de fabricação | |
Meisel et al. | The performance of BRCA1 immunohistochemistry for detecting germline, somatic, and epigenetic BRCA1 loss in high-grade serous ovarian cancer | |
BRPI0602594A (pt) | dispositivo e método para determinação rápida da eficácia de processos de esterilização ou desinfecção | |
BR0210579A (pt) | Anticorpos, cadeias pesadas e leves, composição farmacêutica e métodos de detecção do nìvel de opgl em amostra biológia e de tratamento | |
BRPI0410283A (pt) | métodos de análise de uma região de ácido nucleico marcadora, de detecção ou monitoração de uma população clonal de células em um mamìfero, de diagnóstico e/ou de monitoração de uma condição de doença de mamìfero e de enriquecimento de uma população de moléculas de ácido nucleico em uma amostra biológica | |
Siemund et al. | Establishing aluminium contact allergy | |
TR199902828T2 (xx) | Lizofosfolipidlerin de�i�mi� konsantrasyonlar� ile birle�tirilmi� kanser belirleme y�ntemi. | |
CA3047060A1 (en) | Methods of determining colorectal cancer status in an individual | |
WO2008070663A3 (en) | Companion diagnostic assays for cancer therapy | |
BRPI0809958B8 (pt) | conjunto de esferas para a detecção de uma cepa de hpv e/ou para diferenciação entre duas ou mais cepas de hpv, método para a preparação do referido conjunto de esferas, método para o diagnóstico de infecção por hpv, método para determinação do risco de um indivíduo humano desenvolver uma doença associada a uma ou mais cepas de hpv e par de iniciadores para amplificação de oligonucleotídeo direcionado ao hpv oncogênico | |
Kandárová et al. | Evaluation of the medical devices benchmark materials in the controlled human patch testing and in the RhE in vitro skin irritation protocol | |
BRPI0608429A2 (pt) | método e kit para prognóstico ou avaliação da eficácia do tratamento de um tumor sólido em um paciente de interesse; e método para a identificação de marcadores que sejam prognósticos de um tumor sólido | |
Hegde et al. | Relating tooth‐and blood‐lead levels in children residing near a zinc–lead smelter in India | |
ATE553112T1 (de) | Ttk in der diagnose und als therapeutisches target bei krebs | |
Richards-Rios et al. | Changes in the faecal microbiome of pied tamarins (Saguinus bicolor) associated with chronic, recurrent diarrhoea and weight loss | |
BR9910372A (pt) | Processos para detectar tecido canceroso, e, para realizar um procedimento cirúrgico para remover uma lesão cancerosa de um tecido | |
DE69221040D1 (de) | Aktivätsmessungen des amylin | |
Chappell et al. | Adenovirus 36 antibody detection: Improving the standard serum neutralization assay | |
BR0115689A (pt) | Análise de expressão de inibidor de diferenciação de ácidos nucléicos e polipeptìdeos úteis na diagnose e tratamento de câncer da próstata | |
BR0115728A (pt) | Análise da expressão de ácidos nucléicos kiaa e polipeptìdeos úteis no diagnóstico e tratamento de cáncer de próstata |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 11A ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |