BR0012981A - Sistema para liberação oral de droga hidrodinamicamente balanceado - Google Patents

Sistema para liberação oral de droga hidrodinamicamente balanceado

Info

Publication number
BR0012981A
BR0012981A BR0012981-0A BR0012981A BR0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A BR 0012981 A BR0012981 A BR 0012981A
Authority
BR
Brazil
Prior art keywords
drug
release system
drug release
oral drug
time
Prior art date
Application number
BR0012981-0A
Other languages
English (en)
Inventor
Naresh Talwar
John N Staniforth
Michael J Tobyn
Original Assignee
Ranbaxy Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd filed Critical Ranbaxy Lab Ltd
Publication of BR0012981A publication Critical patent/BR0012981A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007Effervescent

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"SISTEMA PARA LIBERAçãO ORAL DE DROGA HIDRODINAMICAMENTE BALANCEADO". A presente invenção refere-se a um sistema gastro-retentor de liberação oral de droga compreendendo uma matriz de elevada porosidade e, pelo menos, uma droga, açúcar(es) , componentes geradores de gás e, opcionalmente, componentes auxiliares farmaceuticamente aceitáveis. A composição farmacêutica, seja sob a forma de pílulas (forma de dosagem multiparticulada ou unitária), glóbulos, grânulos ou cápsulas é retida no estómago, enquanto a droga é seletivamente liberada a nível gástrico e em partes superiores do intestino delgado por um longo período de tempo.
BR0012981-0A 1999-08-04 2000-08-01 Sistema para liberação oral de droga hidrodinamicamente balanceado BR0012981A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB1999/001386 WO2001010405A1 (en) 1999-08-04 1999-08-04 Hydrodynamically balanced oral drug delivery system
PCT/IB2000/001083 WO2001010419A1 (en) 1999-08-04 2000-08-01 Hydrodynamically balancing oral drug delivery system

Publications (1)

Publication Number Publication Date
BR0012981A true BR0012981A (pt) 2002-06-18

Family

ID=11004886

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012981-0A BR0012981A (pt) 1999-08-04 2000-08-01 Sistema para liberação oral de droga hidrodinamicamente balanceado

Country Status (21)

Country Link
EP (1) EP1206249A4 (pt)
JP (1) JP2003506400A (pt)
CN (1) CN1376059A (pt)
AP (1) AP2002002410A0 (pt)
AU (2) AU5060499A (pt)
BR (1) BR0012981A (pt)
CA (1) CA2378468A1 (pt)
CZ (1) CZ2002415A3 (pt)
EA (1) EA200200126A1 (pt)
HK (1) HK1047226A1 (pt)
HR (1) HRP20020108A2 (pt)
HU (1) HUP0202497A3 (pt)
IL (1) IL147966A0 (pt)
MX (1) MXPA02001272A (pt)
NZ (1) NZ516959A (pt)
OA (1) OA12003A (pt)
PL (1) PL353321A1 (pt)
SK (1) SK1832002A3 (pt)
TR (1) TR200200467T2 (pt)
WO (2) WO2001010405A1 (pt)
ZA (1) ZA200200926B (pt)

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US7776345B2 (en) 2001-07-04 2010-08-17 Sun Pharma Advanced Research Company Ltd Gastric retention controlled drug delivery system
CA2466032A1 (en) * 2001-10-29 2003-05-08 Laure Patricia Ouadji Njiki Methods and dosage forms for improving the bioavailability of therapeutic agents
US20050226926A1 (en) 2002-07-25 2005-10-13 Pfizer Inc Sustained-release tablet composition of pramipexole
AU2004268446A1 (en) * 2003-08-27 2005-03-10 Vecta Ltd. Compositions for treating pathologies that necessitate suppression of gastric acid secretion
TW200533391A (en) 2004-03-25 2005-10-16 Sun Pharmaceutical Ind Ltd Gastric retention drug delivery system
BRPI0513846A (pt) 2004-08-13 2008-05-20 Boehringer Ingelheim Int formulação de comprimido de liberação prolongada contendo pramipexol ou um sal farmaceuticamente aceitável do mesmo, método para a fabricação do mesmo e o uso do mesmo
DE102004042139B4 (de) * 2004-08-31 2009-06-10 Aristocon Verwaltungs- Gmbh Perorale Darreichungsformen zur Erzielung eines Retardierungseffektes nach der Arzneimitteleinnahme mit einer Mahlzeit
EP1690540A1 (en) * 2005-02-15 2006-08-16 Neuro3D Composition comprising ocaperidone
EP1962586B1 (en) 2005-12-22 2017-07-12 Oakwood Laboratories L.L.C. Sublimable sustained release delivery system and method of making same
EP1886665A1 (en) * 2006-08-01 2008-02-13 Boehringer Ingelheim Pharma GmbH & Co. KG Gastro retentive delivery system
WO2008109462A2 (en) * 2007-03-02 2008-09-12 Farnam Companies, Inc. Sustained release pellets comprising wax-like material
WO2010020098A1 (zh) 2008-08-18 2010-02-25 北京天衡药物研究院 胃滞留药物释出***及其制备方法和用途
EP2326310B1 (en) 2008-08-15 2019-05-15 Assertio Therapeutics, Inc. Gastric retentive pharmaceutical compositions for treatment and prevention of cns disorders
CN102307574A (zh) * 2008-10-08 2012-01-04 鲍斯生命科学Pvt有限公司 缓释给药***
EP2283824B1 (en) 2009-07-30 2017-04-19 Special Products Line S.p.A. Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin
JP2013103879A (ja) * 2011-11-10 2013-05-30 Nakanihon Capsule Co Ltd ハードカプセル
KR102241487B1 (ko) 2013-02-20 2021-04-16 주식회사 종근당 제어방출 펠릿으로 된 약제학적 조성물
AU2014228861B2 (en) * 2013-03-15 2018-05-24 Aprecia Pharmaceuticals LLC Rapidly dispersible dosage form of topiramate
CN103462917A (zh) * 2013-09-12 2013-12-25 南京正宽医药科技有限公司 一种用于抗病毒的阿昔洛韦片剂及其制备方法
KR20190033484A (ko) * 2016-06-14 2019-03-29 프레브테크 마이크로비아 인코포레이티드 사료 첨가제를 포함하는 동물 사료 펠릿, 이의 제조 방법 및 사용 방법
US10987311B2 (en) 2017-06-16 2021-04-27 Kashiv Specialty Pharmaceuticals, Llc Extended release compositions comprising pyridostigmine
US10588863B2 (en) 2017-06-16 2020-03-17 Kashiv Biosciences, Llc Extended release compositions comprising pyridostigmine
ES2928071T3 (es) 2017-06-16 2022-11-15 Amneal Complex Products Res Llc Formas de dosificación gastrorretentiva para el suministro sostenido de fármacos
CN107375287B (zh) * 2017-08-22 2019-11-29 安徽省肿瘤医院 一种硫酸阿托品在制备治疗原发性肝癌药物中的用途
CN107349195A (zh) * 2017-08-22 2017-11-17 安徽省肿瘤医院 一种维拉帕米在制备治疗转移性肝癌药物中的用途
CN107441115A (zh) * 2017-08-22 2017-12-08 安徽省肿瘤医院 一种维拉帕米联合碳酸氢钠在制备原发性肝癌治疗药物中的用途
ES2912968T3 (es) 2018-06-18 2022-05-30 Amneal Complex Products Res Llc Composiciones de liberación prolongada que comprenden piridostigmina
CA3065695C (en) 2018-06-27 2021-06-01 Kashiv Biosciences, Llc Self-regulating osmotic gastroretentive drug delivery systems
CA3139217A1 (en) 2019-05-14 2020-11-19 Clexio Biosciences Ltd. Treatment of nocturnal symptoms and morning akinesia in subjects with parkinson's disease
WO2022195476A1 (en) 2021-03-15 2022-09-22 Clexio Biosciences Ltd. Gastroretentive devices for assessment of intragastric conditions

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US5096714A (en) * 1988-06-28 1992-03-17 Hauser-Kuhrts, Inc. Prolonged release drug tablet formulations
WO1991006281A1 (en) * 1989-10-26 1991-05-16 Nippon Shinyaku Co., Ltd. Gastric preparation
MX9300110A (es) * 1992-01-13 1994-07-29 Gerhard Gergely Preparacion farmaceutica en la forma de una tableta de efervescencia o de desintegracion o de un granulado de tipo instanteneo y procedimiento para su preparacion.
GB9322314D0 (en) * 1993-10-29 1993-12-15 Scherer Ltd R P Foam generating capsules
DE4403943A1 (de) * 1994-02-08 1995-08-10 Hexal Pharma Gmbh Orale Azrneimittelzubereitung mit Diclofenac-Natrium
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IT1293764B1 (it) * 1997-07-23 1999-03-10 Chiesi Farma Spa Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua

Also Published As

Publication number Publication date
NZ516959A (en) 2003-10-31
IL147966A0 (en) 2002-09-12
WO2001010419A1 (en) 2001-02-15
CN1376059A (zh) 2002-10-23
AU5060499A (en) 2001-03-05
AP2002002410A0 (en) 2002-03-31
HK1047226A1 (zh) 2003-02-14
HRP20020108A2 (en) 2003-12-31
HUP0202497A3 (en) 2004-05-28
ZA200200926B (en) 2002-11-27
EP1206249A4 (en) 2004-12-22
CZ2002415A3 (cs) 2002-08-14
MXPA02001272A (es) 2002-07-22
TR200200467T2 (tr) 2002-08-21
CA2378468A1 (en) 2001-02-15
EP1206249A1 (en) 2002-05-22
AU774957B2 (en) 2004-07-15
SK1832002A3 (en) 2002-08-06
WO2001010405A1 (en) 2001-02-15
JP2003506400A (ja) 2003-02-18
EA200200126A1 (ru) 2002-10-31
AU6309900A (en) 2001-03-05
HUP0202497A2 (hu) 2002-11-28
PL353321A1 (en) 2003-11-17
OA12003A (en) 2006-04-18

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.