IT1293764B1 - Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua - Google Patents

Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua

Info

Publication number
IT1293764B1
IT1293764B1 IT97MI001746A ITMI971746A IT1293764B1 IT 1293764 B1 IT1293764 B1 IT 1293764B1 IT 97MI001746 A IT97MI001746 A IT 97MI001746A IT MI971746 A ITMI971746 A IT MI971746A IT 1293764 B1 IT1293764 B1 IT 1293764B1
Authority
IT
Italy
Prior art keywords
water
pharmaceutical compositions
tablets containing
effervescent tablets
effervescent
Prior art date
Application number
IT97MI001746A
Other languages
English (en)
Inventor
Paolo Chiesi
Paolo Ventura
Rosa Mezzadri
Gaetano Brambilla
Daniela Acerbi
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Priority to IT97MI001746A priority Critical patent/IT1293764B1/it
Priority to BRPI9801335-1A priority patent/BR9801335B1/pt
Priority to ES98941377T priority patent/ES2191960T3/es
Priority to HU0003897A priority patent/HU226115B1/hu
Priority to NZ502479A priority patent/NZ502479A/en
Priority to SK92-2000A priority patent/SK284551B6/sk
Priority to DE69811236T priority patent/DE69811236T2/de
Priority to PL338502A priority patent/PL199164B1/pl
Priority to AT98941377T priority patent/ATE232092T1/de
Priority to US09/463,224 priority patent/US6284272B1/en
Priority to EP98941377A priority patent/EP1003486B1/en
Priority to EA200000062A priority patent/EA002608B1/ru
Priority to PT98941377T priority patent/PT1003486E/pt
Priority to CZ20000255A priority patent/CZ296221B6/cs
Priority to AU89777/98A priority patent/AU743186B2/en
Priority to CNB988082624A priority patent/CN1138535C/zh
Priority to JP2000503825A priority patent/JP4801255B2/ja
Priority to KR10-2000-7000710A priority patent/KR100528141B1/ko
Priority to PCT/EP1998/004517 priority patent/WO1999004765A2/en
Priority to TR1999/00675T priority patent/TR199900675T1/xx
Priority to IL13416698A priority patent/IL134166A/xx
Priority to DK98941377T priority patent/DK1003486T3/da
Priority to SI9830384T priority patent/SI1003486T1/xx
Publication of ITMI971746A1 publication Critical patent/ITMI971746A1/it
Publication of IT1293764B1 publication Critical patent/IT1293764B1/it
Application granted granted Critical
Priority to BG103253A priority patent/BG64074B1/bg
Priority to OA9900061A priority patent/OA10999A/en
Priority to NO19991376A priority patent/NO326639B1/no
Priority to HK01100275A priority patent/HK1029525A1/xx
Priority to US09/932,097 priority patent/US6667056B2/en
Priority to US10/726,546 priority patent/US20040151768A1/en
Priority to US12/605,558 priority patent/US20100047184A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT97MI001746A 1997-07-23 1997-07-23 Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua IT1293764B1 (it)

Priority Applications (30)

Application Number Priority Date Filing Date Title
IT97MI001746A IT1293764B1 (it) 1997-07-23 1997-07-23 Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua
BRPI9801335-1A BR9801335B1 (pt) 1997-07-23 1998-03-10 composições farmacêuticas sob forma de comprimidos efervescentes contendo um princìpio ativo instável na presença de água.
PCT/EP1998/004517 WO1999004765A2 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
JP2000503825A JP4801255B2 (ja) 1997-07-23 1998-07-23 沸騰性酸−塩基対を含有する製薬学的組成物
SK92-2000A SK284551B6 (sk) 1997-07-23 1998-07-23 Farmaceutický prípravok vo forme šumivej tablety
DE69811236T DE69811236T2 (de) 1997-07-23 1998-07-23 Ein brause-säure-basepaar enthaltende arzneimittel
PL338502A PL199164B1 (pl) 1997-07-23 1998-07-23 Stała, szybko ropuszczalna kompozycja farmaceutyczna, podawana doustnie
AT98941377T ATE232092T1 (de) 1997-07-23 1998-07-23 Ein brause-säure-basepaar enthaltende arzneimittel
US09/463,224 US6284272B1 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
EP98941377A EP1003486B1 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
EA200000062A EA002608B1 (ru) 1997-07-23 1998-07-23 Фармацевтические композиции, содержащие шипучую кислотно-основную пару
PT98941377T PT1003486E (pt) 1997-07-23 1998-07-23 Composicoes farmaceuticas contendo um par acido-base efervescente
HU0003897A HU226115B1 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
AU89777/98A AU743186B2 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
ES98941377T ES2191960T3 (es) 1997-07-23 1998-07-23 Composiciones farmaceuticas que contienen un par acido-base efervescente.
NZ502479A NZ502479A (en) 1997-07-23 1998-07-23 Effervescent tablet containing an acid component and an alkaline component (sodium glycine carbonate)
CNB988082624A CN1138535C (zh) 1997-07-23 1998-07-23 含有泡腾酸碱对的药物组合物
KR10-2000-7000710A KR100528141B1 (ko) 1997-07-23 1998-07-23 발포 산기 결합을 포함하는 약제조성물
TR1999/00675T TR199900675T1 (xx) 1997-07-23 1998-07-23 Bir efervesan asit-baz �iftini ihtiva eden farmas�tik bile�imler.
IL13416698A IL134166A (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
DK98941377T DK1003486T3 (da) 1997-07-23 1998-07-23 Farmaceutisk præparat indeholdende et bruse-syre-basepar
SI9830384T SI1003486T1 (en) 1997-07-23 1998-07-23 Pharmaceutical compositions containing an effervescent acid-base couple
CZ20000255A CZ296221B6 (cs) 1997-07-23 1998-07-23 Farmaceutický prostredek ve forme sumivé tablety,zahrnující aktivní slozku a efervescentní pár
BG103253A BG64074B1 (bg) 1997-07-23 1999-03-15 Фармацевтични състави, съдържащи ефервесцентна киселина-база двойка
OA9900061A OA10999A (en) 1997-07-23 1999-03-19 Pharmaceutical compositions containing an effervescent acid-base couple
NO19991376A NO326639B1 (no) 1997-07-23 1999-03-22 Farmasoytiske sammensetninger inneholdende et brusende syre-base par
HK01100275A HK1029525A1 (en) 1997-07-23 2001-01-11 Pharmaceutical compositions containing an effervescent acid-base couple
US09/932,097 US6667056B2 (en) 1997-07-23 2001-08-20 Pharmaceutical compositions containing an effervescent acid-base couple
US10/726,546 US20040151768A1 (en) 1997-07-23 2003-12-04 Pharmaceutical compositions containing an effervescent acid-base couple
US12/605,558 US20100047184A1 (en) 1997-07-23 2009-10-26 Pharmaceutical compositions containing an effervescent acid-base couple

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT97MI001746A IT1293764B1 (it) 1997-07-23 1997-07-23 Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua

Publications (2)

Publication Number Publication Date
ITMI971746A1 ITMI971746A1 (it) 1999-01-23
IT1293764B1 true IT1293764B1 (it) 1999-03-10

Family

ID=11377613

Family Applications (1)

Application Number Title Priority Date Filing Date
IT97MI001746A IT1293764B1 (it) 1997-07-23 1997-07-23 Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua

Country Status (27)

Country Link
US (1) US6284272B1 (it)
EP (1) EP1003486B1 (it)
JP (1) JP4801255B2 (it)
KR (1) KR100528141B1 (it)
CN (1) CN1138535C (it)
AT (1) ATE232092T1 (it)
AU (1) AU743186B2 (it)
BG (1) BG64074B1 (it)
BR (1) BR9801335B1 (it)
CZ (1) CZ296221B6 (it)
DE (1) DE69811236T2 (it)
DK (1) DK1003486T3 (it)
EA (1) EA002608B1 (it)
ES (1) ES2191960T3 (it)
HK (1) HK1029525A1 (it)
HU (1) HU226115B1 (it)
IL (1) IL134166A (it)
IT (1) IT1293764B1 (it)
NO (1) NO326639B1 (it)
NZ (1) NZ502479A (it)
OA (1) OA10999A (it)
PL (1) PL199164B1 (it)
PT (1) PT1003486E (it)
SI (1) SI1003486T1 (it)
SK (1) SK284551B6 (it)
TR (1) TR199900675T1 (it)
WO (1) WO1999004765A2 (it)

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US20040151768A1 (en) * 1997-07-23 2004-08-05 Chiesi Farmaceutici S.P.A. Pharmaceutical compositions containing an effervescent acid-base couple
FR2786395A1 (fr) * 1998-12-01 2000-06-02 Virbac Sa Compositions seches solubles en presence d'eau et evitant la reaction de maillard a l'etat sec, leur preparation et leurs applications
WO2001001992A1 (en) * 1999-07-02 2001-01-11 Sca Lohnherstellungs Ag A solid formulation of glucosamine sulphate
AU5060499A (en) * 1999-08-04 2001-03-05 Ranbaxy Laboratories Limited Hydrodynamically balanced oral drug delivery system
IN190018B (it) * 1999-09-28 2003-05-31 Panacea Biotec Ltd
GB0006897D0 (en) * 2000-03-23 2000-05-10 Smithkline Beecham Plc Medicaments
DK1309315T3 (da) * 2000-08-18 2006-10-09 Pharmacia Corp Hurtigt disintegrerende oral valdecoxib-formulering
CN1638739A (zh) * 2000-08-18 2005-07-13 法玛西雅厄普约翰美国公司 治疗成瘾性障碍的化合物
US6531153B2 (en) * 2001-05-29 2003-03-11 Drugtech Corporation Composition with sustained release of levodopa and carbidopa
US6762153B2 (en) * 2001-10-18 2004-07-13 Rohm And Haas Company Delivery system for cyclopropenes
US20030091627A1 (en) * 2001-10-31 2003-05-15 Vinay Sharma Rate-controlled delivery of macrolides
KR100456273B1 (ko) * 2001-11-16 2004-11-10 김용년 산과 반응하여 일정 속도로 이산화탄소를 발생시킬 수있는 고상 제제 및 그의 제조 방법
US7488496B2 (en) * 2002-03-06 2009-02-10 Christer Rosen Effervescent compositions comprising bisphosphonates and methods related thereto
ES2448501T3 (es) 2002-03-06 2014-03-14 Effrx Pharmaceuticals Sa Composiciones efervescentes que comprenden bisfosfonatos
BG730Y1 (bg) * 2003-03-20 2005-04-30 Владимир НАЙДЕНОВ Ефервесцентна лекарствена форма
CN100445263C (zh) * 2003-04-24 2008-12-24 四川大学 甘氨酸钠碳酸盐的微波合成方法
FR2876911B1 (fr) * 2004-10-21 2007-04-13 Pierre Fabre Medicament Sa Complexe comprenant du piroxicam, une cyclodextrine et de l'arginine
JP5091661B2 (ja) 2004-04-01 2012-12-05 ピエール ファーブル メディカモン 超臨界ｃｏ２と錯体相互作用剤を用いる方法によって得られる包接錯体
JP2008500288A (ja) * 2004-05-28 2008-01-10 イメイジノット ピーティーワイ エルティーディー 経口治療用化合物の供給系
US8216610B2 (en) * 2004-05-28 2012-07-10 Imaginot Pty Ltd. Oral paracetamol formulations
WO2007002516A2 (en) * 2005-06-23 2007-01-04 Spherics, Inc. Improved dosage forms for movement disorder treatment
CN100341488C (zh) * 2005-11-22 2007-10-10 瑞普（保定）生物药业有限公司 一种饮水免疫泡腾片及其制备方法
EP3449928A1 (en) * 2005-11-28 2019-03-06 Imaginot Pty Ltd. Oral therapeutic compound delivery system
US20080131492A1 (en) * 2006-06-23 2008-06-05 Spherics, Inc. Dosage forms for movement disorder treatment
US20100316712A1 (en) * 2006-12-22 2010-12-16 Combinatorx, Incorporated Pharmaceutical compositions for treatment of parkinson's disease and related disorders
EP2155159B1 (en) * 2007-05-08 2019-07-10 Hercules LLC Robust rapid disintegration tablet formulation
US8377474B2 (en) 2007-12-28 2013-02-19 Impax Laboratories, Inc. Controlled release formulations of levodopa and uses thereof
US9629806B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
US9629809B2 (en) 2008-07-21 2017-04-25 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
AU2011228758A1 (en) * 2010-03-13 2012-11-08 Eastpond Laboratories Limited Fat-binding compositions
CN101836951B (zh) * 2010-05-20 2013-06-05 山东达因海洋生物制药股份有限公司 一种含盐酸氨溴索的口服溶液及其制备方法
CN102322123B (zh) * 2011-06-30 2013-09-18 德清艺玛工艺装饰有限公司 一种仿大理石泡沫装饰材料
CN102398378A (zh) * 2011-11-03 2012-04-04 北京华禧联合科技发展有限公司 镀铬冲模在硫酸氢氯吡格雷片制备过程中的应用
CA2894272A1 (en) * 2012-12-14 2014-06-19 Si Group, Inc. High content sodium ibuprofen granules, their preparation and their use in preparing non-effervescent solid dosage forms
EP3782614A1 (en) 2013-10-07 2021-02-24 Impax Laboratories, LLC Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
US10987313B2 (en) 2013-10-07 2021-04-27 Impax Laboratories, Llc Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof
EP2870961B1 (en) * 2013-11-06 2018-07-18 Sanovel Ilac Sanayi ve Ticaret A.S. Effervescent formulations of pramipexole
EP3758754A1 (en) 2018-03-02 2021-01-06 Chiesi Farmaceutici S.p.A. A pharmaceutical formulation for intraduodenal administration comprising melevodopa and carbidopa
US11986449B2 (en) 2020-12-22 2024-05-21 Amneal Pharmaceuticals Llc Levodopa dosing regimen

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ATE76747T1 (de) * 1986-06-10 1992-06-15 Chiesi Farma Spa Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
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DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
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JP3170139B2 (ja) * 1994-04-08 2001-05-28 エスエス製薬株式会社 発泡性錠剤
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Also Published As

Publication number Publication date
US6284272B1 (en) 2001-09-04
SI1003486T1 (en) 2003-08-31
HUP0003897A3 (en) 2006-06-28
HK1029525A1 (en) 2001-04-06
PL338502A1 (en) 2000-11-06
PL199164B1 (pl) 2008-08-29
OA10999A (en) 2001-11-07
AU8977798A (en) 1999-02-16
IL134166A (en) 2005-08-31
CZ296221B6 (cs) 2006-02-15
KR100528141B1 (ko) 2005-11-15
BG103253A (en) 1999-09-30
EA200000062A1 (ru) 2000-10-30
WO1999004765A3 (en) 1999-06-10
HUP0003897A2 (hu) 2001-08-28
DK1003486T3 (da) 2003-05-19
NZ502479A (en) 2002-02-01
NO326639B1 (no) 2009-01-26
SK284551B6 (sk) 2005-06-02
EP1003486B1 (en) 2003-02-05
NO991376D0 (no) 1999-03-22
BR9801335A (pt) 1999-05-04
SK922000A3 (en) 2000-07-11
ES2191960T3 (es) 2003-09-16
NO991376L (no) 1999-05-25
IL134166A0 (en) 2001-04-30
BR9801335B1 (pt) 2010-09-21
BG64074B1 (bg) 2003-12-31
TR199900675T1 (xx) 1999-11-22
AU743186B2 (en) 2002-01-17
EA002608B1 (ru) 2002-06-27
ITMI971746A1 (it) 1999-01-23
CN1138535C (zh) 2004-02-18
KR20010022140A (ko) 2001-03-15
CN1267215A (zh) 2000-09-20
HU226115B1 (en) 2008-04-28
PT1003486E (pt) 2003-06-30
JP4801255B2 (ja) 2011-10-26
EP1003486A2 (en) 2000-05-31
JP2001510789A (ja) 2001-08-07
WO1999004765A2 (en) 1999-02-04
DE69811236T2 (de) 2003-10-30
ATE232092T1 (de) 2003-02-15
CZ2000255A3 (cs) 2000-07-12
DE69811236D1 (de) 2003-03-13

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