BR0008766A - Sistema de vetor de rna de componente múltiplo para expressão de sequências estranhas - Google Patents

Sistema de vetor de rna de componente múltiplo para expressão de sequências estranhas

Info

Publication number
BR0008766A
BR0008766A BR0008766-1A BR0008766A BR0008766A BR 0008766 A BR0008766 A BR 0008766A BR 0008766 A BR0008766 A BR 0008766A BR 0008766 A BR0008766 A BR 0008766A
Authority
BR
Brazil
Prior art keywords
vector system
rna vector
expression
component rna
rnas
Prior art date
Application number
BR0008766-1A
Other languages
English (en)
Inventor
Dennis J Lewandowski
William O Dawson
Thomas H Turpen
Gregory P Poque
Original Assignee
Large Scale Biology Corp
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Large Scale Biology Corp, Univ Florida filed Critical Large Scale Biology Corp
Publication of BR0008766A publication Critical patent/BR0008766A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • C12N15/8203—Virus mediated transformation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"SISTEMA DE VETOR DE RNA DE COMPONENTE MúLTIPLO PARA EXPRESSãO DE SEQuêNCIAS ESTRANHAS". A presente invenção caracteriza um sistema de vetor de RNA de componente múltiplo, que consiste de replicons de RNA derivados de vírus de RNA e vírus auxiliadores. A presente invenção também caracteriza um processo para produção de RNAs estranhos, RNAs de efetuador, proteínas ou peptídeos em plantas usando o sistema de vetor de RNA de componente múltiplo. Além disto, a presente invenção provê um processo para produção sistêmica e estável de RNAs estranhos, RNAs efetuadores proteínas e peptídeos usando o sistema de vetor de RNA de componente múltiplo.
BR0008766-1A 1999-03-09 2000-03-08 Sistema de vetor de rna de componente múltiplo para expressão de sequências estranhas BR0008766A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26557599A 1999-03-09 1999-03-09
PCT/US2000/005929 WO2000053780A2 (en) 1999-03-09 2000-03-08 Multiple component rna vector system for expression of foreign sequences

Publications (1)

Publication Number Publication Date
BR0008766A true BR0008766A (pt) 2002-04-09

Family

ID=23011023

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008766-1A BR0008766A (pt) 1999-03-09 2000-03-08 Sistema de vetor de rna de componente múltiplo para expressão de sequências estranhas

Country Status (11)

Country Link
US (1) US20020138873A1 (pt)
EP (1) EP1165811A2 (pt)
JP (1) JP2002537842A (pt)
KR (1) KR20020013508A (pt)
AU (1) AU3618300A (pt)
BR (1) BR0008766A (pt)
CA (1) CA2372306A1 (pt)
IL (1) IL145221A0 (pt)
MX (1) MXPA01009043A (pt)
NZ (1) NZ514055A (pt)
WO (1) WO2000053780A2 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10049587A1 (de) 2000-10-06 2002-05-02 Icon Genetics Ag Vektorsystem für Pflanzen
WO2005019449A2 (en) * 2003-07-03 2005-03-03 Board Of Trustees Operating Michigan State University Expression of a recombinant transgene
ES2346224T4 (es) * 2003-11-10 2011-06-01 Icon Genetics Gmbh Sistema de expresión de planta derivado de virus de arn.
MXPA06003715A (es) 2003-11-10 2006-06-23 Icon Genetics Ag Sistema de expresion de planta derivado de virus de arn.
EP1564295A1 (en) * 2004-01-23 2005-08-17 Icon Genetics AG RNA virus-derived plant expression system
EP1616959A1 (en) 2004-07-07 2006-01-18 Icon Genetics AG Biological safe transient protein expression in plants
WO2014147235A1 (en) 2013-03-22 2014-09-25 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Kits comprising plus-sense single stranded rna viral vectors and methods for producing polypeptides using the kits
WO2017162266A1 (en) 2016-03-21 2017-09-28 Biontech Rna Pharmaceuticals Gmbh Rna replicon for versatile and efficient gene expression
WO2017162265A1 (en) 2016-03-21 2017-09-28 Biontech Rna Pharmaceuticals Gmbh Trans-replicating rna
WO2018010815A1 (en) 2016-07-15 2018-01-18 Biontech Rna Pharmaceuticals Gmbh Formulation for administration of rna
CN111094549A (zh) 2017-09-13 2020-05-01 生物技术Rna制药有限公司 用于将体细胞重编程的rna复制子
JP7389741B2 (ja) 2017-09-13 2023-11-30 バイオエヌテック セル アンド ジーン セラピーズ ゲーエムベーハー Ｔ細胞受容体または人工ｔ細胞受容体を発現するためのｒｎａレプリコン
EP3737386A1 (en) 2018-01-11 2020-11-18 BioNTech RNA Pharmaceuticals GmbH Formulation for administration of rna
EP3908328A1 (en) 2019-01-10 2021-11-17 BioNTech RNA Pharmaceuticals GmbH Localized administration of rna molecules for therapy
JP2023527910A (ja) 2020-06-04 2023-06-30 バイオエヌテック エスエー 多用途かつ効率的な遺伝子発現のためのｒｎａレプリコン

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1288073C (en) * 1985-03-07 1991-08-27 Paul G. Ahlquist Rna transformation vector
WO1997049814A1 (en) * 1996-06-21 1997-12-31 Plant Genetic Systems, N.V. Gene expression in plants

Also Published As

Publication number Publication date
NZ514055A (en) 2001-09-28
WO2000053780A2 (en) 2000-09-14
US20020138873A1 (en) 2002-09-26
MXPA01009043A (es) 2003-07-21
JP2002537842A (ja) 2002-11-12
AU3618300A (en) 2000-09-28
EP1165811A2 (en) 2002-01-02
IL145221A0 (en) 2002-12-01
KR20020013508A (ko) 2002-02-20
CA2372306A1 (en) 2000-09-14
WO2000053780A3 (en) 2000-12-21

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]