BG30927A3 - Method for obtaining of trans- 4- alpha- phenyl- octahydro- 1h- 2- pyridine - Google Patents

Method for obtaining of trans- 4- alpha- phenyl- octahydro- 1h- 2- pyridine

Info

Publication number
BG30927A3
BG30927A3 BG7841785A BG4178578A BG30927A3 BG 30927 A3 BG30927 A3 BG 30927A3 BG 7841785 A BG7841785 A BG 7841785A BG 4178578 A BG4178578 A BG 4178578A BG 30927 A3 BG30927 A3 BG 30927A3
Authority
BG
Bulgaria
Prior art keywords
octahydro
trans
pyridine
alpha
phenyl
Prior art date
Application number
BG7841785A
Other languages
Bulgarian (bg)
English (en)
Inventor
Zimmerman
Original Assignee
Eli Lilly And Co.,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co.,Us filed Critical Eli Lilly And Co.,Us
Publication of BG30927A3 publication Critical patent/BG30927A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG7841785A 1977-12-27 1978-12-19 Method for obtaining of trans- 4- alpha- phenyl- octahydro- 1h- 2- pyridine BG30927A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86489977A 1977-12-27 1977-12-27

Publications (1)

Publication Number Publication Date
BG30927A3 true BG30927A3 (en) 1981-09-15

Family

ID=25344312

Family Applications (1)

Application Number Title Priority Date Filing Date
BG7841785A BG30927A3 (en) 1977-12-27 1978-12-19 Method for obtaining of trans- 4- alpha- phenyl- octahydro- 1h- 2- pyridine

Country Status (24)

Country Link
EP (1) EP0002937A1 (xx)
JP (1) JPS5498770A (xx)
AR (1) AR221352A1 (xx)
AU (1) AU4286678A (xx)
BE (1) BE872990A (xx)
BG (1) BG30927A3 (xx)
CA (1) CA1105026A (xx)
CS (1) CS203940B2 (xx)
DD (1) DD141156A5 (xx)
DK (1) DK577078A (xx)
ES (1) ES476385A1 (xx)
FI (1) FI783992A (xx)
FR (1) FR2413370A1 (xx)
GB (1) GB2010806A (xx)
GR (1) GR70349B (xx)
IL (1) IL56268A0 (xx)
IT (1) IT1101682B (xx)
LU (1) LU80719A1 (xx)
NZ (1) NZ189230A (xx)
PL (1) PL117572B1 (xx)
PT (1) PT68934A (xx)
RO (1) RO75805A (xx)
SU (1) SU841586A3 (xx)
ZA (1) ZA787156B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415736A (en) * 1981-12-28 1983-11-15 E. I. Du Pont De Nemours & Co. Certain tetrahydropyridine intermediates
US4537963A (en) * 1981-12-28 1985-08-27 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-E]isoquinolines
US4579952A (en) * 1981-12-28 1986-04-01 E. I. Du Pont De Nemours And Company Intermediates for octahydrobenzofuro[3,2-e]isoquinolines
FR2617481B1 (fr) * 1987-07-03 1989-11-10 Roussel Uclaf Nouveaux derives de la tetrahydropyridine, leur procede de preparation et les intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant
US8598164B2 (en) 2010-05-06 2013-12-03 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
SI2670752T1 (sl) 2011-02-02 2016-10-28 Vertex Pharmaceuticals Incorporated Pirolopirazin-spirociklični piperidin amidi kot modulatorji ionskih kanalčkov
EP2675812B1 (en) 2011-02-18 2017-08-30 Vertex Pharmaceuticals Incorporated Chroman - spirocyclic piperidine amides as modulators of ion channels
AU2012229187B2 (en) 2011-03-14 2016-11-10 Vertex Pharmaceuticals Incorporated Morpholine-spirocyclic piperidine amides as modulators of ion channels
KR102306951B1 (ko) * 2013-07-10 2021-10-01 버텍스 파마슈티칼스 인코포레이티드 이온 채널의 조절제로서의 융합된 피페리딘 아미드

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1024149A (en) * 1972-07-20 1978-01-10 E.I. Du Pont De Nemours And Company 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES
AT330179B (de) * 1972-07-20 1976-06-25 Du Pont Verfahren zur herstellung von neuen 4a-aryl- transdecahydroisochinolinderivaten sowie deren optischen isomeren
PT67194B (en) * 1976-11-02 1979-03-23 Lilly Co Eli Process for preparing 4a-aryl-octahydro-1h-2-pyrindines

Also Published As

Publication number Publication date
ZA787156B (en) 1980-08-27
JPS5498770A (en) 1979-08-03
NZ189230A (en) 1981-05-15
ES476385A1 (es) 1979-11-16
PL211919A1 (pl) 1979-09-10
DD141156A5 (de) 1980-04-16
FI783992A (fi) 1979-06-28
FR2413370A1 (fr) 1979-07-27
IL56268A0 (en) 1979-03-12
RO75805A (ro) 1981-02-28
BE872990A (fr) 1979-06-22
CA1105026A (en) 1981-07-14
IT7831268A0 (it) 1978-12-22
LU80719A1 (fr) 1979-04-13
CS203940B2 (en) 1981-03-31
AR221352A1 (es) 1981-01-30
IT1101682B (it) 1985-10-07
PL117572B1 (en) 1981-08-31
GB2010806A (en) 1979-07-04
DK577078A (da) 1979-06-28
PT68934A (en) 1979-01-01
EP0002937A1 (en) 1979-07-11
SU841586A3 (ru) 1981-06-23
AU4286678A (en) 1979-07-05
GR70349B (xx) 1982-09-23

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