BG106437A - Антиконвулсивно и противострахово действащи 4-амино-1-арил-1, 5-дихидро-пирол-2-они и метод за получаването им - Google Patents
Антиконвулсивно и противострахово действащи 4-амино-1-арил-1, 5-дихидро-пирол-2-они и метод за получаването им Download PDFInfo
- Publication number
- BG106437A BG106437A BG06437A BG10643702A BG106437A BG 106437 A BG106437 A BG 106437A BG 06437 A BG06437 A BG 06437A BG 10643702 A BG10643702 A BG 10643702A BG 106437 A BG106437 A BG 106437A
- Authority
- BG
- Bulgaria
- Prior art keywords
- dihydro
- pyrrol
- morpholin
- chlorophenyl
- 2one
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19944332A DE19944332A1 (de) | 1999-09-16 | 1999-09-16 | Antikonvulsiv und anxiolytisch wirkende 4-Amino-1-aryl-1,5-dihydro-pyrrol-2-one und Verfahren zu deren Herstellung |
PCT/EP2000/008572 WO2001019793A1 (de) | 1999-09-16 | 2000-09-02 | Antikonvulsiv und anxiolytisch wirkende 4-amino-1-aryl-1,5-dihydro-pyrrol-2-one und verfahren zu deren darstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
BG106437A true BG106437A (bg) | 2002-09-30 |
Family
ID=7922190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG06437A BG106437A (bg) | 1999-09-16 | 2002-02-26 | Антиконвулсивно и противострахово действащи 4-амино-1-арил-1, 5-дихидро-пирол-2-они и метод за получаването им |
Country Status (20)
Country | Link |
---|---|
US (1) | US6500821B1 (sk) |
EP (1) | EP1212297A1 (sk) |
JP (1) | JP2003509407A (sk) |
KR (1) | KR20020027657A (sk) |
CN (1) | CN1374948A (sk) |
AR (1) | AR025700A1 (sk) |
AU (1) | AU7283000A (sk) |
BG (1) | BG106437A (sk) |
BR (1) | BR0013961A (sk) |
CA (1) | CA2317257A1 (sk) |
CZ (1) | CZ2002915A3 (sk) |
DE (1) | DE19944332A1 (sk) |
EE (1) | EE200200137A (sk) |
HU (1) | HUP0202607A3 (sk) |
IL (1) | IL147808A0 (sk) |
MX (1) | MXPA02001370A (sk) |
NO (1) | NO20021143L (sk) |
SK (1) | SK3782002A3 (sk) |
TR (1) | TR200200678T2 (sk) |
WO (1) | WO2001019793A1 (sk) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106008304B (zh) * | 2016-05-18 | 2018-07-17 | 湖北科技学院 | 一种1,3-二氢吡咯-2-酮类化合物及其合成方法 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH543504A (de) * | 1971-03-25 | 1973-10-31 | Lonza Ag | Verfahren zur Herstellung 1-substituierter 4-Aminopyrrolin-3-one-(2) |
US4511568A (en) | 1982-05-12 | 1985-04-16 | Ici Americas Inc. | CNS-Depressant pyrazolopyridines |
-
1999
- 1999-09-16 DE DE19944332A patent/DE19944332A1/de not_active Withdrawn
-
2000
- 2000-08-30 CA CA002317257A patent/CA2317257A1/en not_active Abandoned
- 2000-08-31 US US09/652,488 patent/US6500821B1/en not_active Expired - Fee Related
- 2000-09-02 AU AU72830/00A patent/AU7283000A/en not_active Abandoned
- 2000-09-02 CN CN00812985A patent/CN1374948A/zh active Pending
- 2000-09-02 EE EEP200200137A patent/EE200200137A/xx unknown
- 2000-09-02 WO PCT/EP2000/008572 patent/WO2001019793A1/de not_active Application Discontinuation
- 2000-09-02 BR BR0013961-0A patent/BR0013961A/pt not_active Application Discontinuation
- 2000-09-02 JP JP2001523373A patent/JP2003509407A/ja active Pending
- 2000-09-02 SK SK378-2002A patent/SK3782002A3/sk unknown
- 2000-09-02 MX MXPA02001370A patent/MXPA02001370A/es unknown
- 2000-09-02 HU HU0202607A patent/HUP0202607A3/hu unknown
- 2000-09-02 EP EP00960584A patent/EP1212297A1/de not_active Withdrawn
- 2000-09-02 IL IL14780800A patent/IL147808A0/xx unknown
- 2000-09-02 CZ CZ2002915A patent/CZ2002915A3/cs unknown
- 2000-09-02 KR KR1020027003491A patent/KR20020027657A/ko not_active Application Discontinuation
- 2000-09-02 TR TR2002/00678T patent/TR200200678T2/xx unknown
- 2000-09-15 AR ARP000104877A patent/AR025700A1/es unknown
-
2002
- 2002-02-26 BG BG06437A patent/BG106437A/bg unknown
- 2002-03-07 NO NO20021143A patent/NO20021143L/no unknown
Also Published As
Publication number | Publication date |
---|---|
JP2003509407A (ja) | 2003-03-11 |
TR200200678T2 (tr) | 2002-07-22 |
HUP0202607A2 (hu) | 2002-12-28 |
CA2317257A1 (en) | 2001-03-16 |
US6500821B1 (en) | 2002-12-31 |
NO20021143D0 (no) | 2002-03-07 |
BR0013961A (pt) | 2002-05-21 |
AU7283000A (en) | 2001-04-17 |
HUP0202607A3 (en) | 2003-05-28 |
MXPA02001370A (es) | 2004-09-10 |
CN1374948A (zh) | 2002-10-16 |
KR20020027657A (ko) | 2002-04-13 |
NO20021143L (no) | 2002-03-07 |
EP1212297A1 (de) | 2002-06-12 |
AR025700A1 (es) | 2002-12-11 |
EE200200137A (et) | 2003-04-15 |
SK3782002A3 (en) | 2002-07-02 |
WO2001019793A1 (de) | 2001-03-22 |
CZ2002915A3 (cs) | 2002-06-12 |
DE19944332A1 (de) | 2001-03-22 |
IL147808A0 (en) | 2002-08-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP2023144075A (ja) | 癌治療用ptpn11(shp2)阻害剤としての6-(4-アミノ-3-メチル-2-オキサ-8-アザスピロ[4.5]デカン-8-イル)-3-(2,3-ジクロロフェニル)-2-メチルピリミジン-4(3h)-オン誘導体及び関連化合物 | |
KR100296837B1 (ko) | 5h-티아졸로[3,2-a]피리미딘유도체,이의제조방법및이를포함하는약제학적조성물 | |
EP0858996B1 (en) | Nerve cell protective agents | |
PL214701B1 (pl) | Pochodna piperydyny, kompozycja farmaceutyczna zawierajaca te pochodna oraz zastosowanie lecznicze tej pochodnej | |
SK279977B6 (sk) | 4-amino-2-(4-metylpiperazín-1-yl)-5-(2,3,5--trichl | |
HU179917B (en) | Process for preparing pyridino- and azepino-triazole derivatives | |
NL8502141A (nl) | 5h-2,3-benzodiazepinederivaten, werkwijze voor de bereiding ervan en farmaceutische preparaten met dergelijke verbindingen erin. | |
DE19636769A1 (de) | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung | |
FR2501506A1 (fr) | Compositions pharmaceutiques a action anorexigene contenant des derives de la tetrahydropyridine | |
WO1992014465A1 (de) | Verwendung von anellierten tetrahydropyridinessigsäurederivaten für die behandlung neurologischer erkrankungen | |
KR100444697B1 (ko) | 피리도티아진유도체및이를포함하는약제학적조성물 | |
BG106437A (bg) | Антиконвулсивно и противострахово действащи 4-амино-1-арил-1, 5-дихидро-пирол-2-они и метод за получаването им | |
KR20080077889A (ko) | 약제학적 항암 조성물 | |
AU2018356556A1 (en) | New alcoxyamino derivatives for treating pain and pain related conditions | |
DE3503074A1 (de) | Hydantoinderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten | |
JPH01193264A (ja) | 精神***病の治療に有効な1−((5−((4−置換−1−ピペラジニル)メチル)−ピロール−2−イル又はフラン−2−イル)メチル−2−ピペリジノン類 | |
AU688346B2 (en) | Use of efaxoran and its derivatives for the production of drugs for treating neurodegenerative diseases | |
FR2567886A1 (fr) | Derives 1-(2-pyrimidinyl)-piperazinyliques de 1-pyrrolidine-2-ones et leur application psychogeriatrique | |
US5180726A (en) | 4-[4- or 6-(trifluoromethyl-2-pyridinyl)]-1-piperazinylalkyl substituted lactams | |
SK399A3 (en) | Benzo[g]quinoline derivatives, process for their preparation, pharmaceutical composition containing same and their use | |
KR20010074802A (ko) | 항경련 활성을 갖는 신규한 4-아미노-1-아릴피리딘-2-온및 이의 제조방법 | |
JPH07508517A (ja) | 新規ニコチン酸エステル | |
CZ287351B6 (cs) | 4-Amino-2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorfenyl)pyrimidin, způsob jeho výroby a farmaceutický prostředek | |
KR20230159996A (ko) | 신규 옥사다이아졸 유도체 화합물 및 이를 포함하는 신경염증성 질환 예방 또는 치료용 약학적 조성물 | |
JPS59193874A (ja) | 置換アミノ−ピラゾリン |