BE901725A - Nouveaux diazephioindoles, leur preparation et leur utilisation comme medicaments. - Google Patents

Nouveaux diazephioindoles, leur preparation et leur utilisation comme medicaments.

Info

Publication number
BE901725A
BE901725A BE1/11188A BE1011188A BE901725A BE 901725 A BE901725 A BE 901725A BE 1/11188 A BE1/11188 A BE 1/11188A BE 1011188 A BE1011188 A BE 1011188A BE 901725 A BE901725 A BE 901725A
Authority
BE
Belgium
Prior art keywords
preparation
diazephioindoles
medicaments
novel
alkyl
Prior art date
Application number
BE1/11188A
Other languages
English (en)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE901725A publication Critical patent/BE901725A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)

Abstract

Procédé de préparation de 2, 3, 4, 5-tétrahydro-1H-(1,4)diazépino (1,7-a) indoles et leurs sels d'addition avec des acides, dans lesquels: R1 R2 représent H, Hal, CF3, alkyle en C1-C4 R3= H, alkyle en C1-C4, cycloalkyle en C3-C6, alcényle en C3-C5 ou alcynyle en C3-C5. Ces composés peuvent etre utilisés comme médicaments, surtout pour leurs activités anti-dépressives.
BE1/11188A 1984-02-22 1985-02-13 Nouveaux diazephioindoles, leur preparation et leur utilisation comme medicaments. BE901725A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH86384 1984-02-22

Publications (1)

Publication Number Publication Date
BE901725A true BE901725A (fr) 1985-08-13

Family

ID=4196936

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/11188A BE901725A (fr) 1984-02-22 1985-02-13 Nouveaux diazephioindoles, leur preparation et leur utilisation comme medicaments.

Country Status (23)

Country Link
US (1) US4673674A (fr)
JP (1) JPS60202887A (fr)
AT (1) AT388379B (fr)
BE (1) BE901725A (fr)
CA (1) CA1271193A (fr)
DE (1) DE3505017A1 (fr)
DK (1) DK78385A (fr)
ES (2) ES8706681A1 (fr)
FI (1) FI79316C (fr)
FR (1) FR2609715B1 (fr)
GB (1) GB2154584B (fr)
GR (1) GR850443B (fr)
HU (1) HU193083B (fr)
IL (1) IL74388A (fr)
IT (1) IT1199949B (fr)
LU (1) LU85778A1 (fr)
MY (1) MY100083A (fr)
NL (1) NL8500370A (fr)
PH (1) PH22247A (fr)
PL (2) PL146274B1 (fr)
PT (1) PT79990B (fr)
SE (1) SE8500822L (fr)
ZA (1) ZA851373B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3635071A1 (de) * 1986-10-15 1988-04-28 Autoflug Gmbh Rueckenlehnenverriegelung fuer einen mit sicherheitsgurten ausgeruesteten fahrzeugsitz
NZ521389A (en) * 2000-03-14 2005-06-24 Upjohn Co 2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indole compounds
MX2007016403A (es) * 2005-06-27 2008-03-07 Glaxosmithkline Biolog Sa Composicion inmunogenica.
HU230880B1 (hu) * 2015-04-15 2018-11-29 Richter Gedeon Nyrt Indol származékok

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1593146A (en) * 1976-11-05 1981-07-15 Beecham Group Ltd Octahydro-quinolizinyl benzamide derivatives
US4210590A (en) * 1978-01-06 1980-07-01 Mcneil Laboratories, Incorporated Reduction of indole compounds to indoline compounds
CH649553A5 (de) * 1982-05-06 1985-05-31 Sandoz Ag Azepinoindole und verfahren zu deren herstellung.

Also Published As

Publication number Publication date
FR2609715A1 (fr) 1988-07-22
IL74388A (en) 1988-12-30
FI850702A0 (fi) 1985-02-20
NL8500370A (nl) 1985-09-16
HU193083B (en) 1987-08-28
ZA851373B (en) 1986-09-24
PH22247A (en) 1988-07-01
IT8547704A1 (it) 1986-08-20
GR850443B (fr) 1985-06-19
PT79990A (en) 1985-03-01
PL144329B1 (en) 1988-05-31
PL252065A1 (en) 1985-12-03
FI79316B (fi) 1989-08-31
AT388379B (de) 1989-06-12
US4673674A (en) 1987-06-16
GB2154584A (en) 1985-09-11
GB2154584B (en) 1987-09-30
ES8706681A1 (es) 1987-06-16
ATA52285A (de) 1988-11-15
IL74388A0 (en) 1985-05-31
ES540559A0 (es) 1987-06-16
FR2609715B1 (fr) 1989-05-26
ES555042A0 (es) 1987-07-16
GB8504179D0 (en) 1985-03-20
HUT38642A (en) 1986-06-30
IT1199949B (it) 1989-01-05
LU85778A1 (fr) 1985-12-11
SE8500822D0 (sv) 1985-02-20
PT79990B (en) 1987-01-13
MY100083A (en) 1989-08-18
SE8500822L (sv) 1985-08-23
CA1271193A (fr) 1990-07-03
DK78385A (da) 1985-08-23
FI850702L (fi) 1985-08-23
DE3505017A1 (de) 1985-08-22
ES8707204A1 (es) 1987-07-16
IT8547704A0 (it) 1985-02-20
PL146274B1 (en) 1989-01-31
DK78385D0 (da) 1985-02-20
JPS60202887A (ja) 1985-10-14
FI79316C (fi) 1989-12-11

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