BE900618A - 4,5,6,7-TETRAHYDROBENZIMIDAZOLE DERIVATIVES. - Google Patents

4,5,6,7-TETRAHYDROBENZIMIDAZOLE DERIVATIVES.

Info

Publication number
BE900618A
BE900618A BE0/213677A BE213677A BE900618A BE 900618 A BE900618 A BE 900618A BE 0/213677 A BE0/213677 A BE 0/213677A BE 213677 A BE213677 A BE 213677A BE 900618 A BE900618 A BE 900618A
Authority
BE
Belgium
Prior art keywords
substituted
tetrahydrobenzimidazole derivatives
tetrahydrobenzimidazole
derivatives
new
Prior art date
Application number
BE0/213677A
Other languages
French (fr)
Inventor
U Scarponi
R Cimaschi
L Rusconi
R De Castiglione
G Arcari
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE900618A publication Critical patent/BE900618A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Nouveaux dérivés de 4,5,6,7-tétrahydrobenzimidazole de formule générale I ou n = 0 ou 1 ; R1 = alkyle en C1-C6, cycloalkyle en C3-C7, phényle substitué ou non; R2 et R3 = H ou groupes de R1, benzyle substitué ou non; ou R2 et R3 avec N = noyau hétérocyclique pentagonal, hexagonal ou heptagonal. Les nouveaux produits de l'invention sont dotés d'une bonne activité anti-ulcérogène.New 4,5,6,7-tetrahydrobenzimidazole derivatives of general formula I or n = 0 or 1; R1 = C1-C6 alkyl, C3-C7 cycloalkyl, substituted or unsubstituted phenyl; R2 and R3 = H or groups of R1, substituted or unsubstituted benzyl; or R2 and R3 with N = pentagonal, hexagonal or heptagonal heterocyclic ring. The new products of the invention have good anti-ulcerogenic activity.

BE0/213677A 1983-12-16 1984-09-18 4,5,6,7-TETRAHYDROBENZIMIDAZOLE DERIVATIVES. BE900618A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838333513A GB8333513D0 (en) 1983-12-16 1983-12-16 Tetrahydrobenzimidazole derivatives

Publications (1)

Publication Number Publication Date
BE900618A true BE900618A (en) 1985-01-16

Family

ID=10553369

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213677A BE900618A (en) 1983-12-16 1984-09-18 4,5,6,7-TETRAHYDROBENZIMIDAZOLE DERIVATIVES.

Country Status (4)

Country Link
JP (1) JPS60130570A (en)
BE (1) BE900618A (en)
DE (1) DE3434055A1 (en)
GB (2) GB8333513D0 (en)

Also Published As

Publication number Publication date
DE3434055A1 (en) 1985-06-27
GB8422570D0 (en) 1984-10-10
GB8333513D0 (en) 1984-01-25
JPS60130570A (en) 1985-07-12
GB2152036B (en) 1987-04-01
GB2152036A (en) 1985-07-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19890930