BE900617A - TETRAHYDROPYRANNO [3,4-d] IMIDAZOLE AND TETRAHYDROTHIOPYRANNO [3,4-d] IMIDAZOLE DERIVATIVES. - Google Patents

TETRAHYDROPYRANNO [3,4-d] IMIDAZOLE AND TETRAHYDROTHIOPYRANNO [3,4-d] IMIDAZOLE DERIVATIVES.

Info

Publication number
BE900617A
BE900617A BE0/213676A BE213676A BE900617A BE 900617 A BE900617 A BE 900617A BE 0/213676 A BE0/213676 A BE 0/213676A BE 213676 A BE213676 A BE 213676A BE 900617 A BE900617 A BE 900617A
Authority
BE
Belgium
Prior art keywords
imidazole
tetrahydrothiopyranno
tetrahydropyranno
derivatives
alkyl
Prior art date
Application number
BE0/213676A
Other languages
French (fr)
Inventor
U Scarponi
R Cimaschi
R De Castiglione
G Arcari
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of BE900617A publication Critical patent/BE900617A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

L'invention concerne un nouveau (1 ou 3), 4,6,7-tétrahydropyranno(2,3-d) imidazole et de nouveaux dérivés de (1 ou 3), 4,6,7-tétrahydrothiopyranno [3,4-d]imidazole dotés d'une bonne activité anti-ulcérogène et répondant à la formule générale (I) où n = 1 à 4 ; X = O ou S, R1, R2 et R3 = H, alkyle en C1-C4; R4 et R5 = H, alkyle en C1-C10, cycloalyle en C5-C7, benzyle, ou R4 et R5, ensemble avec N forment un noyau hétérocyclique pentagonal ou hexagonal; C4 = configurations R, S ou RS.The invention relates to a new (1 or 3), 4,6,7-tetrahydropyranno (2,3-d) imidazole and to new derivatives of (1 or 3), 4,6,7-tetrahydrothiopyranno [3,4- d] imidazole with good anti-ulcerogenic activity and corresponding to the general formula (I) where n = 1 to 4; X = O or S, R1, R2 and R3 = H, C1-C4 alkyl; R4 and R5 = H, C1-C10 alkyl, C5-C7 cycloalyl, benzyl, or R4 and R5, together with N form a pentagonal or hexagonal heterocyclic ring; C4 = R, S or RS configurations.

BE0/213676A 1983-12-16 1984-09-18 TETRAHYDROPYRANNO [3,4-d] IMIDAZOLE AND TETRAHYDROTHIOPYRANNO [3,4-d] IMIDAZOLE DERIVATIVES. BE900617A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838333512A GB8333512D0 (en) 1983-12-16 1983-12-16 Tetrahydropyrano derivatives

Publications (1)

Publication Number Publication Date
BE900617A true BE900617A (en) 1985-01-16

Family

ID=10553368

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/213676A BE900617A (en) 1983-12-16 1984-09-18 TETRAHYDROPYRANNO [3,4-d] IMIDAZOLE AND TETRAHYDROTHIOPYRANNO [3,4-d] IMIDAZOLE DERIVATIVES.

Country Status (4)

Country Link
JP (1) JPS60130588A (en)
BE (1) BE900617A (en)
DE (1) DE3434056A1 (en)
GB (2) GB8333512D0 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ731621A (en) * 2009-12-04 2019-01-25 Sunovion Pharmaceuticals Inc Multicyclic compounds and methods of use thereof

Also Published As

Publication number Publication date
JPS60130588A (en) 1985-07-12
GB8333512D0 (en) 1984-01-25
GB2152035B (en) 1987-06-24
GB8422569D0 (en) 1984-10-10
GB2152035A (en) 1985-07-31
DE3434056A1 (en) 1985-06-27

Similar Documents

Publication Publication Date Title
FR2639636B1 (en) NOVEL HETEROCYCLIC COMPOUNDS WITH ANTICONVULSIVE ACTIVITY, PREPARATION METHOD AND THERAPEUTIC COMPOSITIONS CONTAINING THEM
FR2560480B3 (en) COMBINATION OF EARTH WORKING TOOLS WITH A SEEDER
DK158085D0 (en) 2-SUBSTITUTED ERGOLINE DERIVATIVES, PROCEDURE FOR PREPARING IT AND THE USE OF IT AS A MEDICINE
ES8705408A1 (en) 1,5-Benzothiazephine derivatives, processes for preparing the same and pharmaceutical compositions.
ES8500247A1 (en) Triazine derivatives, processes for preparation thereof and pharmaceutical compositions comprising the same.
DE3665711D1 (en) NOVEL GUANIDINOMETHYLBENZOIC ACID DERIVATIVES
DK184985D0 (en) PHENOLATE DERIVATIVES, METHOD OF PREPARING THEREOF, AND PHARMACEUTICAL AGENTS CONTAINING THESE
TNSN87135A1 (en) PROCESS FOR THE PREPARATION OF BICYCLIC AMINOCARBOXYLIC ACID DERIVATIVES
DK540585D0 (en) 5-ALKYL-1-PHENYL-2-PIPERAZINOALKYLPYRASOLIN-3-ON COMPOUNDS, PROCEDURES FOR THE PRODUCTION OF IT, AND INTERMEDIATES FOR USE THEREOF, AND PHARMACEUTICAL PREPARATIONS CONTAINED
BE900617A (en) TETRAHYDROPYRANNO [3,4-d] IMIDAZOLE AND TETRAHYDROTHIOPYRANNO [3,4-d] IMIDAZOLE DERIVATIVES.
ES8705421A1 (en) 4-Amino-2-phenyl quinolines, methods and intermediates for their preparation and medicaments containing them.
GB1304392A (en)
ATE58532T1 (en) (2-AMINO-4-ARYL-THIAZOLE-5-YL)AETHANOL AND THEIR DERIVATIVES WITH DIURETIC ACTIVITY AND PROCESS FOR THEIR PRODUCTION.
FR2451921A1 (en) CEPHALOSPORIN TYPE ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC APPLICATION
DE3855121D1 (en) Anxiolytic piperazine derivatives
ES8307826A1 (en) 2,-3-Di-substituted-5,6-dihydroimidazo [2,1-b] thiazole, its salts, production thereof and anti-inflammatory agent containing the same
FR2372839A1 (en) OXAZOLIDINEDIONE DERIVATIVES FROM VINCA ALKALOIDS, WITH ANTITUMOR ACTIVITY
BE900618A (en) 4,5,6,7-TETRAHYDROBENZIMIDAZOLE DERIVATIVES.
BE903699A (en) NOVEL IMIDAZOPYRIDAZINE DERIVATIVES, THEIR PRODUCTION PROCESS AND PHARMACEUTICAL COMPOSITION CONTAINING THEM.
IE37579L (en) Benzodioxan acetamidines
FR2366292A1 (en) NEW TETRACYCLIC COMPOUNDS DERIVED FROM DIAZEPINE-1,4 WITH BIOLOGICAL ACTIVITY
BE901727A (en) DERIVATIVES OF HEXAHYDROAZEPINO 3, 4-D IMIDAZOLES.
ES8308539A1 (en) Aminosulfenyl chloride derivatives
JPS5538397A (en) Diuretic drug
ES2014041A6 (en) Amine derivatives useful as anti-ulcer agents

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19890930