BE888811A - 1-(4-chloorbenzhydryl)-4-(2,3-bis-hydroxypropyl)-piperazine, zijn gebruik als anti-hoesmiddel, antihistaminicum sedativum, analgeticum en ontstekingsremmend middel, alsmede farmaceutische preparaten met deze stof - Google Patents
1-(4-chloorbenzhydryl)-4-(2,3-bis-hydroxypropyl)-piperazine, zijn gebruik als anti-hoesmiddel, antihistaminicum sedativum, analgeticum en ontstekingsremmend middel, alsmede farmaceutische preparaten met deze stofInfo
- Publication number
- BE888811A BE888811A BE2/59160A BE2059160A BE888811A BE 888811 A BE888811 A BE 888811A BE 2/59160 A BE2/59160 A BE 2/59160A BE 2059160 A BE2059160 A BE 2059160A BE 888811 A BE888811 A BE 888811A
- Authority
- BE
- Belgium
- Prior art keywords
- inflammative
- preparator
- chlorobenzhydryl
- histaminic
- analgetic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22283/80A IT1140978B (it) | 1980-05-23 | 1980-05-23 | 1-(4-clorobenzidril)-4-(2,3-diidros sipropil)-piperazina, metodi per la sua preparazione e relative composizione farmaceutiche |
Publications (1)
Publication Number | Publication Date |
---|---|
BE888811A true BE888811A (nl) | 1981-08-28 |
Family
ID=11194137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE2/59160A BE888811A (nl) | 1980-05-23 | 1981-05-15 | 1-(4-chloorbenzhydryl)-4-(2,3-bis-hydroxypropyl)-piperazine, zijn gebruik als anti-hoesmiddel, antihistaminicum sedativum, analgeticum en ontstekingsremmend middel, alsmede farmaceutische preparaten met deze stof |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5731678A (nl) |
BE (1) | BE888811A (nl) |
DE (1) | DE3118162C2 (nl) |
ES (1) | ES8203352A1 (nl) |
FR (1) | FR2482965A1 (nl) |
GB (1) | GB2076403B (nl) |
IT (1) | IT1140978B (nl) |
NL (1) | NL8102361A (nl) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3611276A1 (de) * | 1986-04-04 | 1987-11-26 | Unilever Nv | Verpackung mit margarine oder aehnlichem brotaufstrich |
JPH01226575A (ja) * | 1988-02-25 | 1989-09-11 | Mitsubishi Plastics Ind Ltd | もずくの包装体 |
SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE9904673D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE9904674D0 (sv) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE0001209D0 (sv) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
JP4549024B2 (ja) | 2001-05-18 | 2010-09-22 | アストラゼネカ・アクチエボラーグ | 4(フェニル−ピペラジニル−メチル)ベンズアミド誘導体及び疼痛、不安症又は胃腸障害の治療のためのその使用 |
SE0203300D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203302D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203303D0 (sv) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
DK1781631T3 (da) | 2004-08-02 | 2012-05-14 | Astrazeneca Ab | Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf |
HU227074B1 (en) * | 2005-12-08 | 2010-06-28 | Egis Gyogyszergyar Nyrt | An optically active carbamic acid derivative, method for producing the same and use as a pharmaceutical intermediate |
DE602007012725D1 (de) * | 2007-11-21 | 2011-04-07 | Synthon Bv | Verfahren zur Herstellung von N-(Diphenylmethyl)piperazinen |
US7989623B2 (en) | 2007-11-21 | 2011-08-02 | Synthon Bv | Process for making n-(diphenylmethyl)piperazines |
-
1980
- 1980-05-23 IT IT22283/80A patent/IT1140978B/it active
-
1981
- 1981-05-07 DE DE3118162A patent/DE3118162C2/de not_active Expired
- 1981-05-08 FR FR8109273A patent/FR2482965A1/fr active Granted
- 1981-05-13 NL NL8102361A patent/NL8102361A/nl not_active Application Discontinuation
- 1981-05-15 BE BE2/59160A patent/BE888811A/nl not_active IP Right Cessation
- 1981-05-22 ES ES502429A patent/ES8203352A1/es not_active Expired
- 1981-05-22 GB GB8115827A patent/GB2076403B/en not_active Expired
- 1981-05-23 JP JP7856281A patent/JPS5731678A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
GB2076403B (en) | 1983-11-16 |
GB2076403A (en) | 1981-12-02 |
JPS6135189B2 (nl) | 1986-08-12 |
NL8102361A (nl) | 1981-12-16 |
FR2482965B1 (nl) | 1984-11-23 |
ES502429A0 (es) | 1982-04-01 |
IT1140978B (it) | 1986-10-10 |
JPS5731678A (en) | 1982-02-20 |
DE3118162A1 (de) | 1982-02-18 |
DE3118162C2 (de) | 1984-07-26 |
IT8022283A0 (it) | 1980-05-23 |
FR2482965A1 (fr) | 1981-11-27 |
ES8203352A1 (es) | 1982-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: SELVI & C. S.P.A. Effective date: 19930531 |