BE884407A - Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments - Google Patents

Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments

Info

Publication number
BE884407A
BE884407A BE1/9900A BE1009900A BE884407A BE 884407 A BE884407 A BE 884407A BE 1/9900 A BE1/9900 A BE 1/9900A BE 1009900 A BE1009900 A BE 1009900A BE 884407 A BE884407 A BE 884407A
Authority
BE
Belgium
Prior art keywords
naphtyridine
medicaments
phenyl
derivatives
alkyl
Prior art date
Application number
BE1/9900A
Other languages
English (en)
French (fr)
Inventor
J Nadelson
R Damon
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE884407A publication Critical patent/BE884407A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BE1/9900A 1979-07-25 1980-07-22 Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments BE884407A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6072979A 1979-07-25 1979-07-25

Publications (1)

Publication Number Publication Date
BE884407A true BE884407A (fr) 1981-01-22

Family

ID=22031390

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/9900A BE884407A (fr) 1979-07-25 1980-07-22 Nouveaux derives de la 6-alkyl-7-phenyl-1,6-naphtyridine-5(6h)-one, leur preparation et leur application comme medicaments

Country Status (15)

Country Link
JP (1) JPS5620588A (es)
AU (1) AU6072080A (es)
BE (1) BE884407A (es)
DE (1) DE3027619A1 (es)
DK (1) DK318280A (es)
ES (1) ES493639A0 (es)
FI (1) FI802318A (es)
FR (1) FR2462438A1 (es)
GB (1) GB2054593A (es)
IL (1) IL60672A0 (es)
IT (1) IT8049312A0 (es)
NL (1) NL8004236A (es)
PT (1) PT71592B (es)
SE (1) SE8005303L (es)
ZA (1) ZA804524B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502831A1 (de) * 1985-01-29 1986-07-31 Gödecke AG, 1000 Berlin 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung
US5466697A (en) * 1994-07-13 1995-11-14 Syntex (U.S.A.) Inc. 8-phenyl-1,6-naphthyridin-5-ones
FR2751969B1 (fr) * 1996-08-01 1998-12-04 Centre Nat Rech Scient Composes activateurs du canal cftr, et compositions pharmaceutiques les contenant
EP2313406B1 (de) * 2008-08-05 2015-02-25 Boehringer Ingelheim International GmbH 4-dimethylaminophenyl-substituierte napththyridine und ihre verwendung als arzneimittel
EP2528915B1 (en) 2010-01-29 2015-10-28 Boehringer Ingelheim International GmbH Substituted naphthyridines and their use as syk kinase inhibitors
CN103827090B (zh) 2011-07-26 2016-04-20 勃林格殷格翰国际有限公司 取代的喹啉及其作为药物的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702600A1 (de) * 1977-01-22 1978-07-27 Thomae Gmbh Dr K Neue aminoalkoxyphenyl-derivate

Also Published As

Publication number Publication date
DK318280A (da) 1981-01-26
PT71592A (en) 1980-08-01
ZA804524B (en) 1982-03-31
FR2462438A1 (fr) 1981-02-13
FI802318A (fi) 1981-01-26
ES8105998A1 (es) 1981-07-01
IL60672A0 (en) 1980-09-16
GB2054593A (en) 1981-02-18
JPS5620588A (en) 1981-02-26
DE3027619A1 (de) 1981-02-19
PT71592B (en) 1981-08-11
IT8049312A0 (it) 1980-07-24
AU6072080A (en) 1981-01-29
SE8005303L (sv) 1981-01-26
NL8004236A (nl) 1981-01-27
ES493639A0 (es) 1981-07-01

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