BE882621A - Inhibiteurs de beta-lactamase et procede pour les preparer - Google Patents

Inhibiteurs de beta-lactamase et procede pour les preparer

Info

Publication number: BE882621A
Authority: BE; Belgium
Prior art keywords: beta; preparing; lactamase inhibitors; lactamase; inhibitors
Prior art date: 1979-04-06

Application number

BE0/200106A

Other languages

English (en)

Inventor

P Lombardi

G Franceshi

F Arcamone

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-04-06

Filing date

1980-04-03

Publication date

1980-10-03

1980-04-03 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1980-10-03 Publication of BE882621A publication Critical patent/BE882621A/fr

Links

239000003781 beta lactamase inhibitor Substances 0.000 title 1
229940126813 beta-lactamase inhibitor Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Hydrogenated Pyridines (AREA)
Cephalosporin Compounds (AREA)

BE0/200106A 1979-04-06 1980-04-03 Inhibiteurs de beta-lactamase et procede pour les preparer BE882621A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB7912168		1979-04-06

Publications (1)

Publication Number	Publication Date
BE882621A true BE882621A (fr)	1980-10-03

Family

ID=10504396

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE0/200106A BE882621A (fr)	1979-04-06	1980-04-03	Inhibiteurs de beta-lactamase et procede pour les preparer

Country Status (24)

Country	Link
US (1)	US4269771A (fr)
JP (1)	JPS55139385A (fr)
AT (1)	AT369371B (fr)
AU (1)	AU536673B2 (fr)
BE (1)	BE882621A (fr)
CA (1)	CA1148143A (fr)
CH (1)	CH645645A5 (fr)
CS (1)	CS219273B2 (fr)
DE (1)	DE3012975A1 (fr)
DK (1)	DK144180A (fr)
FI (1)	FI801080A (fr)
FR (1)	FR2453162A1 (fr)
GB (1)	GB2048857B (fr)
GR (1)	GR66673B (fr)
HU (1)	HU182118B (fr)
IE (1)	IE49656B1 (fr)
IL (1)	IL59760A (fr)
IT (1)	IT1196407B (fr)
LU (1)	LU82320A1 (fr)
NL (1)	NL8001919A (fr)
SE (1)	SE8002600L (fr)
SU (1)	SU1152524A3 (fr)
YU (1)	YU93880A (fr)
ZA (1)	ZA802000B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4500457A (en) *	1977-05-09	1985-02-19	Ciba-Geigy Corporation	Process for preparing thia-aza compounds with a beta-lactam ring
AT365594B (de) *	1978-11-24	1982-01-25	Erba Farmitalia	Verfahren zur herstellung von neuen 7-oxo-4-thia1-aza-bicyclo-(3,2,0)heptanderivaten
JPS5625110A (en) *	1978-12-18	1981-03-10	Bristol Myers Co	Antibacterial
US4347183A (en) *	1981-02-02	1982-08-31	Schering Corporation	Process for the synthesis of penems and carbapenems
SU1389680A3 (ru) *	1981-12-11	1988-04-15	Фармиталия Карло Эрба С.П.А. (Фирма)	Способ получени оптически активных пенемов или их солей с щелочными металлами
NO831160L (no) *	1982-04-08	1983-10-10	Erba Farmitalia	Fremstilling av substituerte penem-derivater
GB8321677D0 (en) *	1983-08-11	1983-09-14	Erba Farmitalia	Preparation of penems
US6720445B2 (en)	2000-12-21	2004-04-13	Beacon Laboratories, Inc.	Acetyloxymethyl esters and methods for using the same

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3905965A (en) *	1969-10-17	1975-09-16	Roussel Uclaf	Process of total synthesis of cephalosporin derivatives and intermediates
US4053468A (en) *	1976-02-25	1977-10-11	Smithkline Corporation	Process for preparing 7-oxo cephalosporins and 6-oxo penicillins
LU77306A1 (fr) *	1977-05-09	1979-01-18
EP0000636A1 (fr) *	1977-07-13	1979-02-07	Glaxo Group Limited	Composés dérivés pénème, procédés pour leur préparation, leur utilisation dans les compositions pharmaceutiques et les azétidinones utilisées dans leur préparation
US4168314A (en) *	1977-11-17	1979-09-18	Merck & Co., Inc.	6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
US4155912A (en) *	1977-12-14	1979-05-22	Bristol-Myers Company	2-Methylpenem-3-carboxylic acid antibiotics
EP0003415A3 (fr) *	1978-01-20	1979-08-22	Glaxo Group Limited	Composés bêta-lactames, procédés pour leur préparation, compositions pharmaceutiques les contenant et les intermédiaires pour leur préparation
GB2014574A (en) *	1978-02-16	1979-08-30	Glaxo Group Ltd	Lactam Compounds
JPS5559193A (en) *	1978-09-20	1980-05-02	Glaxo Group Ltd	Bblactam compound

1979
- 1979-11-13 US US06/093,603 patent/US4269771A/en not_active Expired - Lifetime
1980
- 1980-04-01 AT AT0177480A patent/AT369371B/de not_active IP Right Cessation
- 1980-04-01 GB GB8010920A patent/GB2048857B/en not_active Expired
- 1980-04-01 LU LU82320A patent/LU82320A1/fr unknown
- 1980-04-01 NL NL8001919A patent/NL8001919A/nl not_active Application Discontinuation
- 1980-04-01 IT IT21099/80A patent/IT1196407B/it active
- 1980-04-01 AU AU57015/80A patent/AU536673B2/en not_active Ceased
- 1980-04-02 CS CS802289A patent/CS219273B2/cs unknown
- 1980-04-02 CH CH261580A patent/CH645645A5/de not_active IP Right Cessation
- 1980-04-02 IE IE668/80A patent/IE49656B1/en unknown
- 1980-04-02 JP JP4403280A patent/JPS55139385A/ja active Pending
- 1980-04-02 GR GR61611A patent/GR66673B/el unknown
- 1980-04-02 CA CA000349137A patent/CA1148143A/fr not_active Expired
- 1980-04-02 DE DE19803012975 patent/DE3012975A1/de not_active Withdrawn
- 1980-04-02 DK DK144180A patent/DK144180A/da not_active Application Discontinuation
- 1980-04-03 BE BE0/200106A patent/BE882621A/fr not_active IP Right Cessation
- 1980-04-03 FI FI801080A patent/FI801080A/fi not_active Application Discontinuation
- 1980-04-03 SE SE8002600A patent/SE8002600L/xx not_active Application Discontinuation
- 1980-04-03 ZA ZA00802000A patent/ZA802000B/xx unknown
- 1980-04-03 IL IL59760A patent/IL59760A/xx unknown
- 1980-04-03 HU HU80810A patent/HU182118B/hu unknown
- 1980-04-04 SU SU802903400A patent/SU1152524A3/ru active
- 1980-04-04 FR FR8007730A patent/FR2453162A1/fr active Pending
- 1980-04-04 YU YU00938/80A patent/YU93880A/xx unknown

Also Published As

Publication number	Publication date
SU1152524A3 (en)	1985-04-23
FR2453162A1 (fr)	1980-10-31
DK144180A (da)	1980-10-07
YU93880A (en)	1983-02-28
GB2048857A (en)	1980-12-17
IT8021099A0 (it)	1980-04-01
ZA802000B (en)	1981-04-29
IL59760A0 (en)	1980-06-30
SE8002600L (sv)	1980-10-07
JPS55139385A (en)	1980-10-31
ATA177480A (de)	1982-05-15
LU82320A1 (fr)	1980-07-02
IT1196407B (it)	1988-11-16
IL59760A (en)	1983-07-31
FI801080A (fi)	1980-10-07
NL8001919A (nl)	1980-10-08
CA1148143A (fr)	1983-06-14
GB2048857B (en)	1983-05-25
AT369371B (de)	1982-12-27
IE49656B1 (en)	1985-11-13
GR66673B (fr)	1981-04-08
AU536673B2 (en)	1984-05-17
CH645645A5 (de)	1984-10-15
AU5701580A (en)	1980-10-09
DE3012975A1 (de)	1980-10-23
US4269771A (en)	1981-05-26
HU182118B (en)	1983-12-28
CS219273B2 (en)	1983-03-25
IE800668L (en)	1980-10-06

Legal Events

Date

Code

Title

Description

1986-10-31

RE

Patent lapsed

Owner name: FARMITALIA CARLO ERBA S.P.A.

Effective date: 19860430

Publication	Publication Date	Title
FR2472562B1 (fr)	1988-01-22	Procede pour preparer des acides hydroxyalkylaminosulfoniques
BE883058A (fr)	1980-08-18	Procede et machine pour fabriquer des gateaux
RO82279A (fr)	1984-05-12	Aerosol procede et installation pour le preparer
RO77272A (fr)	1981-08-17	Procede pour preparer o-methaliloxyphenole
BE867935A (fr)	1978-12-08	Procede pour preparer des hydrocarbylsulfonates alcalino-terreux surbasiques
FR2532415B1 (fr)	1987-03-27	Procede et interferometre pour mesurer des distances courtes
BE882621A (fr)	1980-10-03	Inhibiteurs de beta-lactamase et procede pour les preparer
BE854699A (fr)	1977-09-16	9-(2-0-acyl-beta -d-arabinofurannosyl)adenines et procede pour les preparer
FR2543958B1 (fr)	1986-12-26	Composes 2-thiacephem et procede pour les preparer
FR2549046B1 (fr)	1987-10-09	6-desoxyanthracyclines et procede pour les preparer
RO82358A (fr)	1984-03-15	Procede pour preparer 1-(p-methoxybenzoyl)-3-hydroxy-2-pyrolidinone
BE863700A (fr)	1978-05-29	Azetidinones et procede pour les preparer
BE864415A (fr)	1978-08-28	Diaryldithiophosphates metalliques et procede pour les preparer
BE896217A (fr)	1983-07-18	Liposomes et procede pour les preparer
BE848349A (fr)	1977-05-16	Antibiotiques et procede pour les preparer,
BE852187A (fr)	1977-09-07	Nouvelles cephalosporines et procede pour les preparer
BE854698A (fr)	1977-09-16	9-(5-0-acyl-beta -d-arabinofurannosyl)adenines et procede pour les preparer
BE871957A (fr)	1979-03-01	13,14-didehydro-prostaglandines et procede pour les preparer
FR2457284B1 (fr)	1985-12-27	1a-hydroxy-25-ceto-27-nor-cholecalciferol et procede pour le preparer
RO77032A (fr)	1981-08-30	Procede pour preparer 3-amino-5-tert-butylisoxazole
RO79971A (fr)	1983-02-01	Procede pour preparer 11,17,21-trihydroxypregna-4-en-3,20-dione
BE885319R (fr)	1981-03-19	2-vinyl-chromones substituees et procede pour les preparer
FR2467843B1 (fr)	1986-04-25	Procede pour preparer les derives carbamyle d'a-hydroxy-acides et les a-hydroxy-acides correspondants
FR2346369A1 (fr)	1977-10-28	Thioesters de la doxorubicine et procede pour les preparer
BE867678A (fr)	1978-11-30	Procede pour preparer de l'o-cinnamylphenol